|
8
|
99
|
1bveA |
Hiv-1 protease-dmp323 complex in solution, nmr, 28 structures |
|
84
|
330
|
5isjA |
Endothiapepsin in complex with chiral chlorinated primary amine fragment |
|
87
|
330
|
5is4A |
Endothiapepsin in complex with chiral brominated primary amine fragment |
|
85
|
330
|
5iskA |
Endothiapepsin in complex with fluorinated primary amine fragment |
|
83
|
330
|
5j25A |
Endothiapepsin in complex with fragment 158 |
|
96
|
389
|
3uqpA |
Crystal structure of bace1 with its inhibitor |
|
96
|
388
|
3u6aA |
Rational design and synthesis of aminopiperazinones as beta secretase (bace) inhibitors |
|
96
|
391
|
3uqxA |
Crystal structure of bace1 with its inhibitor |
|
89
|
389
|
3uqrA |
Crystal structure of bace1 with its inhibitor |
|
95
|
390
|
3uquA |
Crystal structure of bace1 with its inhibitor |
|
16
|
99
|
3s85A |
Discovery of new hiv protease inhibitors with potential for convenient dosing and reduced side effects: a-790742 and a-792611. |
|
18
|
99
|
3sacA |
Crystal structure of wild-type hiv-1 protease in complex with af80 |
|
18
|
99
|
3sa4A |
Crystal structure of wild-type hiv-1 protease in complex with af72 |
|
18
|
99
|
3saaA |
Crystal structure of wild-type hiv-1 protease in complex with af77 |
|
18
|
99
|
3sa7A |
Crystal structure of wild-type hiv-1 protease in complex with af55 |
|
19
|
99
|
3sa5A |
Crystal structure of wild-type hiv-1 protease in complex with af69 |
|
18
|
99
|
3sa8A |
Crystal structure of wild-type hiv-1 protease in complex with kb83 |
|
18
|
99
|
3sa6A |
Crystal structure of wild-type hiv-1 protease in complex with af71 |
|
18
|
99
|
3sa3A |
Crystal structure of wild-type hiv-1 protease in complex with ag23 |
|
88
|
323
|
1apwE |
Crystallographic analysis of transition state mimics bound to penicillopepsin: difluorostatine-and difluorostatone-containing peptides |
|
85
|
323
|
1aptE |
Crystallographic analysis of a pepstatin analogue binding to the aspartyl proteinase penicillopepsin at 1.8 angstroms resolution |
|
88
|
339
|
5sxnA |
Structure-based design of a new series of n-piperidin-3-ylpyrimidine-5-carboxamides as renin inhibitors |
|
89
|
336
|
5koqA |
Discovery of tak-272: a novel, potent and orally active renin in-hibitor |
|
17
|
99
|
5kqzA |
Protease e35d-cap2 |
|
86
|
337
|
5kosA |
Discovery of tak-272: a novel, potent and orally active renin in-hibitor |
|
19
|
99
|
5kr0A |
Protease e35d-apv |
|
90
|
387
|
5kr8A |
(4~{s},6~{s})-4-[2,4-bis(fluoranyl)phenyl]-6-(3,5-dimethyl-1,2-oxazol-4-yl)-4-methyl-5,6-dihydro-1,3-thiazin-2-amine (compound 5) bound to bace1 |
|
16
|
99
|
5kr1A |
Protease pr5-drv |
|
17
|
99
|
5kqxA |
Protease e35d-sqv |
|
18
|
99
|
5jfpA |
Hiv-1 wild type protease with grl-097-13a (a adamantane p1-ligand with bis-thf in p2 and isobutylamine in p1') |
|
92
|
375
|
5jodA |
Structure of proplasmepsin iv from plasmodium falciparum |
|
18
|
99
|
5jfuA |
Hiv-1 wild type protease with grl-007-14a (a adamantane p1-ligand with bis-thf in p2 and benzylamine in p1') |
|
18
|
99
|
5ivtA |
Crystal structure of hiv protease complexed with [(1s)-1-[(s)-(4-chlorophenyl)-(3,5-difluorophenyl)methyl]-2-[[5-fluoro-4-[2-[(2r,5s)-5-(2,2,2-trifluoroethylcarbamoyloxymethyl)morpholin-4-ium-2-yl]ethyl]pyridin-1-ium-3-yl]amino]-2-oxo-ethyl]ammonium |
|
18
|
99
|
5ivrA |
Crystal structure of hiv protease complexed with methyl n-[(1s)-1-[[2-[(3s)-3-[(4-aminophenyl)methylamino]-4-hydroxy-butyl]phenyl]carbamoyl]-2,2-diphenyl-ethyl]carbamate |
|
16
|
99
|
5ivqA |
Crystal structure of hiv protease complexed with methyl n-[(1s)-1-benzhydryl-2-(3-morpholin-4-ium-2-ylpropylamino)-2-oxo-ethyl]carbamate |
|
74
|
323
|
5i70A |
Crystal structure of plasmepsin iv |
|
90
|
387
|
5ie1A |
Crystal structure of bace1 in complex with 3-(2-amino-6-(o-tolyl)quinolin-3-yl)-n-(3,3-dimethylbutyl)propanamide |
|
100
|
389
|
5i3xA |
Crystal structure of bace1 in complex with aminoquinoline inhibitor 6 |
|
92
|
388
|
5i3wA |
Crystal structure of bace1 in complex with 2-aminooxazoline-3-azaxanthene inhibitor 2 |
|
94
|
387
|
5i3yA |
Crystal structure of bace1 in complex with aminoquinoline inhibitor 9 |
|
16
|
99
|
5hvpA |
Crystallographic analysis of a complex between human immunodeficiency virus type 1 protease and acetyl-pepstatin at 2.0-angstroms resolution |
|
104
|
390
|
5hu0A |
Bace1 in complex with 4-(3-(furan-2-carboxamido)phenyl)-1-methyl-5-oxo-4-phenylimidazolidin-2-iminium |
|
107
|
391
|
5htzA |
Bace1 in complex with (s)-5-(3-chloro-5-(5-(prop-1-yn-1-yl)pyridin-3-yl)thiophen-2-yl)-2,5-dimethyl-1,2,4-thiadiazinan-3-iminium 1,1-dioxide |
|
102
|
391
|
5hu1A |
Bace1 in complex with (r)-n-(3-(3-amino-2,5-dimethyl-1,1-dioxido-5,6-dihydro-2h-1,2,4-thiadiazin-5-yl)-4-fluorophenyl)-5-fluoropicolinamide |
|
102
|
390
|
5ezxA |
Crystal structure of bace-1 in complex with {(1r,2r)-2-[(r)-2-amino-4-(4-difluoromethoxy-phenyl)-4,5-dihydro-oxazol-4-yl]-cyclopropyl}-(5-chloro-pyridin-3-yl)-methanone |
|
14
|
99
|
7upjA |
Hiv-1 protease/u101935 complex |
|
17
|
99
|
9hvpA |
Design, activity and 2.8 angstroms crystal structure of a c2 symmetric inhibitor complexed to hiv-1 protease |
|
12
|
99
|
8hvpA |
Structure at 2.5-angstroms resolution of chemically synthesized human immunodeficiency virus type 1 protease complexed with a hydroxyethylene*-based inhibitor |
|
14
|
99
|
7hvpA |
X-ray crystallographic structure of a complex between a synthetic protease of human immunodeficiency virus 1 and a substrate-based hydroxyethylamine inhibitor |
|
16
|
99
|
6upjA |
Hiv-2 protease/u99294 complex |
