1CA4A

Structure of tnf receptor associated factor 2 (traf2)
Total Genus 41
204060801001201401600510152025303540
Genus TraceResidueGenus

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
168
structure length
168
Chain Sequence
AMADLEQKVLEMEASTYDGVFIWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQNNREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDLTGL

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
molecule tags Tnf signaling
source organism Homo sapiens
publication title Structural basis for self-association and receptor recognition of human TRAF2.
pubmed doi rcsb
molecule keywords PROTEIN (TNF RECEPTOR ASSOCIATED FACTOR 2)
total genus 41
structure length 168
sequence length 168
chains with identical sequence B, C, D, E, F
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 1999-02-23
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.210.10 Mainly Beta Sandwich Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A 1ca4A00
1CA9A 1CZZA 2CR2A 4JJQA 1KZZA 1ZMSA 3IVQA 4CA1A 1L0AA 1RF3A 1F3VB 2F1ZA 2FOPA 3HQIA 4I7BA 1FLLA 2GKWA 5H9MA 4K8UA 2XXNA 2F1YA 3MQRA 1D0JA 2F1WA 1FLKA 2A25A 3IVVA 1K2FA 1YZEA 3HQMA 3HU6A 3HQLA 4O1VA 3HSVA 4M4EA 4X3GA 1LB5A 3MQSC 1LB4A 2FOJA 4GJHA 4GWNA 2FOOA 4Z8MA 1CA4A 4I7DA 1D00A 3HQHA 3IVBA 4I7CA 4KG9A 1QSCA 5E1TA 1D01A 4GHUA 1D0AA 4GWMA 3ZJBA 1YY6A 1LB6A 2AN6A 2F1XA 1CZYA 4YSIA 4C9ZA
chains in the Genus database with same CATH superfamily
1CA9A 1CZZA 2CR2A 4JJQA 1KZZA 1ZMSA 3IVQA 4CA1A 1L0AA 1RF3A 1F3VB 2F1ZA 2FOPA 3HQIA 4I7BA 1FLLA 2GKWA 5H9MA 4K8UA 2XXNA 2F1YA 3MQRA 1D0JA 2F1WA 1FLKA 2A25A 3IVVA 1K2FA 1YZEA 3HQMA 3HU6A 3HQLA 4O1VA 3HSVA 4M4EA 4X3GA 1LB5A 3MQSC 1LB4A 2FOJA 4GJHA 4GWNA 2FOOA 4Z8MA 1CA4A 4I7DA 1D00A 3HQHA 3IVBA 4I7CA 4KG9A 1QSCA 5E1TA 1D01A 4GHUA 1D0AA 4GWMA 3ZJBA 1YY6A 1LB6A 2AN6A 2F1XA 1CZYA 4YSIA 4C9ZA
chains in the Genus database with same CATH topology
1CA9A 1CZZA 2CR2A 4JJQA 1KZZA 1ZMSA 3IVQA 4CA1A 1L0AA 1RF3A 1F3VB 2F1ZA 2FOPA 3HQIA 4I7BA 1FLLA 2GKWA 5H9MA 4K8UA 2XXNA 2F1YA 3MQRA 1D0JA 2F1WA 1FLKA 2A25A 3IVVA 1K2FA 1YZEA 3HQMA 3HU6A 3HQLA 4O1VA 3HSVA 4M4EA 4X3GA 1LB5A 3MQSC 1LB4A 2FOJA 4GJHA 4GWNA 2FOOA 4Z8MA 1CA4A 4I7DA 1D00A 3HQHA 3IVBA 4I7CA 4KG9A 1QSCA 5E1TA 1D01A 4GHUA 1D0AA 4GWMA 3ZJBA 1YY6A 1LB6A 2AN6A 2F1XA 1CZYA 4YSIA 4C9ZA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 1CA9 A;  1CZZ A;  2CR2 A;  4JJQ A;  1KZZ A;  1ZMS A;  3IVQ A;  4CA1 A;  1L0A A;  1RF3 A;  1F3V B;  2F1Z A;  2FOP A;  3HQI A;  4I7B A;  1FLL A;  2GKW A;  5H9M A;  4K8U A;  2XXN A;  2F1Y A;  3MQR A;  1D0J A;  2F1W A;  1FLK A;  2A25 A;  3IVV A;  1K2F A;  1YZE A;  3HQM A;  3HU6 A;  3HQL A;  4O1V A;  3HSV A;  4M4E A;  4X3G A;  1LB5 A;  3MQS C;  1LB4 A;  2FOJ A;  4GJH A;  4GWN A;  2FOO A;  4Z8M A;  1CA4 A;  4I7D A;  1D00 A;  3HQH A;  3IVB A;  4I7C A;  4KG9 A;  1QSC A;  5E1T A;  1D01 A;  4GHU A;  1D0A A;  4GWM A;  3ZJB A;  1YY6 A;  1LB6 A;  2AN6 A;  2F1X A;  1CZY A;  4YSI A;  4C9Z A; 
#chains in the Genus database with same CATH topology
 1CA9 A;  1CZZ A;  2CR2 A;  4JJQ A;  1KZZ A;  1ZMS A;  3IVQ A;  4CA1 A;  1L0A A;  1RF3 A;  1F3V B;  2F1Z A;  2FOP A;  3HQI A;  4I7B A;  1FLL A;  2GKW A;  5H9M A;  4K8U A;  2XXN A;  2F1Y A;  3MQR A;  1D0J A;  2F1W A;  1FLK A;  2A25 A;  3IVV A;  1K2F A;  1YZE A;  3HQM A;  3HU6 A;  3HQL A;  4O1V A;  3HSV A;  4M4E A;  4X3G A;  1LB5 A;  3MQS C;  1LB4 A;  2FOJ A;  4GJH A;  4GWN A;  2FOO A;  4Z8M A;  1CA4 A;  4I7D A;  1D00 A;  3HQH A;  3IVB A;  4I7C A;  4KG9 A;  1QSC A;  5E1T A;  1D01 A;  4GHU A;  1D0A A;  4GWM A;  3ZJB A;  1YY6 A;  1LB6 A;  2AN6 A;  2F1X A;  1CZY A;  4YSI A;  4C9Z A; 
#chains in the Genus database with same CATH homology
 1CA9 A;  1CZZ A;  2CR2 A;  4JJQ A;  1KZZ A;  1ZMS A;  3IVQ A;  4CA1 A;  1L0A A;  1RF3 A;  1F3V B;  2F1Z A;  2FOP A;  3HQI A;  4I7B A;  1FLL A;  2GKW A;  5H9M A;  4K8U A;  2XXN A;  2F1Y A;  3MQR A;  1D0J A;  2F1W A;  1FLK A;  2A25 A;  3IVV A;  1K2F A;  1YZE A;  3HQM A;  3HU6 A;  3HQL A;  4O1V A;  3HSV A;  4M4E A;  4X3G A;  1LB5 A;  3MQS C;  1LB4 A;  2FOJ A;  4GJH A;  4GWN A;  2FOO A;  4Z8M A;  1CA4 A;  4I7D A;  1D00 A;  3HQH A;  3IVB A;  4I7C A;  4KG9 A;  1QSC A;  5E1T A;  1D01 A;  4GHU A;  1D0A A;  4GWM A;  3ZJB A;  1YY6 A;  1LB6 A;  2AN6 A;  2F1X A;  1CZY A;  4YSI A;  4C9Z A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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