4I7CA

Siah1 mutant bound to synthetic peptide (ace)klrpv(23p)mvrpwvr
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
192
structure length
188
Chain Sequence
ANSVLFPCKYASSGCEITLPHTEKADHEELCEFRPYSCPCPGASCKWQGSLDAVMPHLMHQHKSICTLQGEDIVFLATDINLPGAVDWVMMQSCFGFHFMLVLEKQEKQQFFAIVQLIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHEGIATAIMNSDCLVFDTSIAQLFAENGNLGINVTISMC
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-based design of covalent siah inhibitors.
pubmed doi rcsb
molecule tags Ligase/ligase inhibitor
source organism Homo sapiens
molecule keywords E3 ubiquitin-protein ligase SIAH1
total genus 45
structure length 188
sequence length 192
chains with identical sequence C
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2012-11-30
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.210.10 Mainly Beta Sandwich Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A 4i7cA02
3.30.40.10 Alpha Beta 2-Layer Sandwich Herpes Virus-1 Zinc/RING finger domain, C3HC4 (zinc finger) 4i7cA01
2VP7A 2HYED 2M85A 2ZETC 4WZ0A 4UP0A 4A0CD 2OXQC 2FOJA 1WEQA 3LQHA 1HYIA 1YZEA 3SOWA 2JMJA 2F1XA 1G25A 2K16A 2PUYA 4I7CA 4UI9B 2E6RA 4QF2A 5G05B 4P5OB 3U5OA 2C2LA 4KG9A 2ECNA 2YHNA 1WEOA 4YBSA 1RF3A 2FOOA 5TDWA 1WGMA 2MNZA 4XI1A 2LGLA 2BAYA 2DX8A 4R2YA 1D0JA 2F1ZA 3O34A 3T6RA 5H1TA 2LXPC 4GHUA 3HU6A 3ZPVE 1LDKC 1Z60A 4V3KC 4BHWA 4WZ3B 2K1JA 3C5KA 5D1MB 4A4BA 3HCSA 3GL6A 1WEEA 5G04B 3ZJBA 4QF3A 2JRJA 4N4FA 2LGVA 5H1UA 3L1ZB 4AYCA 4AYCB 3ZVYA 5B77A 2KU3A 2ECJA 2H0DA 2H0DB 2K4DA 2G45A 2F1WA 3N9LA 2LXHC 2C2VS 1WEMA 2MA5A 3LQIA 3MHSA 2ECTA 2YU4A 3PUQA 2YSMA 4ZQLA 3M99A 1K2FA 1D01A 3N9MA 4YADA 4GNGA 4GB0A 2VNFA 1WEVA 3RPGC 1X4JA 5JG6A 5KH7A 2F6JA 1BORA 4R7EA 3HQLA 3N9QA 3I2DA 2MD8C 2VJFA 2VJFB 5LKTA 4LLBA 2MD7B 5DINA 5B75A 4BBQA 1WIMA 2MA6A 1CA4A 2FOPA 4GNDA 3LRQA 1FBVA 3PHDA 4LK9A 4A49A 2XEUA 3HQHA 4CCGX 3KV6A 3DPLR 3GV4A 2Y1NA 2YREA 2L43A 3IVQA 2EA6A 2MNYA 3N9NA 5D1LB 2CR2A 4X3GA 2YQMA 4IC2A 5TBNA 2VPGA 2I50A 3ASLA 2VPBA 4GJHA 5H1VA 5FB1A 4YSIA 2G43A 5AIUA 4W4UA 3N9PA 3EB6A 3RPGB 2IDAA 1E4UA 3HTKC 4YABA 1WEWA 2K17A 2YQLA 4K8UA 5KH3A 2AN6A 1HYJA 4B86C 3MQSC 2LV9A 4FJCA 1CZYA 4PTBA 2PNXA 1WE9A 1XWHA 5LKXA 1FP0A 4AUQB 3PURA 5B78A 4O64A 5TRBA 4MVTA 3U5NA 1Z6UA 1N87A 2KR4A 3RTRB 4ZDTA 3VK6A 2ECWA 1MM2A 1F62A 2KWJA 1RMDA 5AITA 2ECIA 4LJNA 2EGPA 1WENA 1VD4A 5LKZA 3DQVR 4I7DA 1MM3A 5FB0A 5E1TA 3L1XA 5FEYA 3MQRA 2FUIA 2LN0A 5DKAA 5C11A 4CA1A 3IHPA 3HCUA 4R8PK 4YBMA 3EB5A 2L75A 2MUMA 1X4UA 4ZUXU 2JMDA 2F42A 4YAXA 2HDPA 2YURA 1WESA 4UP5A 2CT2A 2D8SA 5D1KB 3KQIA 1ZMSA 5EYAF 2YT5A 2YUCA 5KH9A 1CA9A 2Y43A 4F52B 2KE1A 1D00A 4GNFA 5I3LA 3ZVZB 1LB4A 2YYRA 3O37A 2L0BA 5C13A 3C6WA 4V3LC 5B79A 4I7BA 2F6NA 4A4CA 3O7AA 4GWMA 3LQJA 3QZVA 1VFYA 4MSXA 4N3WA 4WZ2A 3IVVA 2KYUA 3MHHA 2G6QA 3ZTGA 4C9ZA 2KFTA 4YATA 2Y1MA 4FO9A 5B76A 3ZYQA 2MIQA 1YY6A 1V87A 2KGGA 3HSVA 2KIZA 4O1VA 4YBTA 2LGKA 2UZGA 3N9OA 4Q6FA 2NAAA 5G0FA 2RI7A 1D0AA 1X4IA 4LADB 4Z8MA 3SHBA 2CKLB 2CKLA 5LCWB 3SOXA 3O36A 3HQIA 2LRIC 3O33A 2LQ6A 4GWNA 4L58A 3L11A 4WA6A 3ZNIA 3FL2A 2KWNA 3NG2A 5FERA 4TKPB 3SOUA 2E6SA 1IYMA 1FLKA 4B7YC 3ZPV1 1WFKA 3U5MA 1Z2QA 1LB6A 2EODA 4LKAA 1LB5A 1U6GB 3KNVA 5TABA 2ECGA 4YC9A 3KV5A 2M6MA 1CHCA 4AVXA 1JOCA 2M1RA 2JMIA 4S3OB 2KWOA 3IVBA 2GKWA 2CSYA 1F3VB 2YSJA 2F1YA 3HCTA 1WILA 3HQMA 2CSZA 2YW8A 1FLLA 5J3XA 2VPEA 2XXNA 2VJEA 2VJEB 4PPEA 2RSDA 3M63A 4JJQA 2MT5A 1LDJB 4L7XA 4NN2A 1DVPA 3T7LA 2FSAA 4M4EA 1VYXA 1WEPA 2M3HA 1CZZA 2FUUA 3V43A 2QIZA 1KZZA 2L80A 4IC3A 1WEUA 2L5UA 2XB1A 5TDRA 2LGGA 2QJ0A 1JM7A 1JM7B 5B8DA 1ZBDB 2ECVA 2YHOA 1QSCA 4S3OC 2KGIA 2KWKA 4FIPA 5H9MA 4GNEA 1T1HA 2VPDA 2KREA 4FK5A 3U5PA 1L0AA 4AP4A 3M62A 3O35A 2A25A 3O70A 5LKUA 2QICA 2LDRA
chains in the Genus database with same CATH superfamily
2VP7A 2HYED 3LVRE 3FAOA 2M85A 2ZETC 4WZ0A 4UP0A 4A0CD 2OXQC 2FOJA 1WEQA 3LQHA 1HYIA 1YZEA 3SOWA 2JMJA 2JUNA 4H9DA 1DCQA 2F1XA 1G25A 2OWAA 2K16A 2E61A 2PUYA 4I7CA 4UI9B 2E6RA 2B0OE 4QF2A 5G05B 4P5OB 3U5OA 2JM3A 2C2LA 2DJAA 4KG9A 2ECNA 2YHNA 1WEOA 4YBSA 1RF3A 2FOOA 5TDWA 1WGMA 2MNZA 4XI1A 3SUBA 2LGLA 2BAYA 2DX8A 4R2YA 5SVYA 1D0JA 2F1ZA 3O34A 3T6RA 5H1TA 2LXPC 4GHUA 3HU6A 3ZPVE 1LDKC 1Z60A 4V3KC 4BHWA 4WZ3B 2K1JA 3C5KA 5D1MB 4A4BA 3HCSA 3GL6A 1WEEA 5G04B 3ZJBA 4QF3A 2JRJA 4N4FA 2LGVA 5H1UA 3L1ZB 4AYCA 4AYCB 3DWDA 3ZVYA 5B77A 2KU3A 2ECJA 2H0DA 2H0DB 2K4DA 4F1PA 2G45A 2F1WA 2KKXA 3N9LA 2LXHC 2L7PA 2C2VS 1WEMA 2MA5A 3H7HA 3LQIA 3MHSA 2ECTA 2YU4A 3PUQA 2YSMA 2IQJA 4ZQLA 3M99A 1K2FA 1D01A 3N9MA 4YADA 4GNGA 4GB0A 2VNFA 1WEVA 3RPGC 1X4JA 5JG6A 2YVRA 5KH7A 2F6JA 3FANA 1BORA 4R7EA 3HQLA 3N9QA 2CSVA 3I2DA 2MD8C 2VJFA 2VJFB 5LKTA 4LLBA 2MD7B 5DINA 5B75A 4BBQA 1WIMA 2MA6A 1CA4A 2FOPA 3DDTA 4GNDA 3LRQA 1FBVA 3PHDA 4LK9A 2D8UA 4A49A 2XEUA 3HQHA 2LAUA 4CCGX 3KV6A 3DPLR 3GV4A 2Y1NA 2YREA 2EGMA 2L43A 3IVQA 2EA6A 2MNYA 3N9NA 5D1LB 2CR2A 4X3GA 2YQMA 4IC2A 5TBNA 2VPGA 2I50A 3ASLA 2VPBA 4GJHA 5H1VA 5FB1A 4YSIA 5SVXA 2G43A 5AIUA 3M7KA 4W4UA 3N9PA 3EB6A 3RPGB 2IDAA 1E4UA 3HTKC 4YABA 1WEWA 2K17A 2YQLA 4K8UA 5KH3A 2AN6A 1HYJA 4Z0RA 4B86C 3MQSC 2LV9A 4FJCA 1CZYA 4PTBA 2PNXA 1WE9A 1XWHA 4OGEA 5LKXA 1FP0A 2DSMA 4AUQB 3PURA 2P57A 5B78A 4O64A 5TRBA 4MVTA 3U5NA 4O62A 1Z6UA 1N87A 2KR4A 3RTRB 2CONA 4ZDTA 3VK6A 2ECWA 1MM2A 2EXUA 1F62A 2KWJA 1RMDA 5AITA 2ECIA 4LJNA 2EGPA 1WENA 2MKEA 1VD4A 5LKZA 3DQVR 4I7DA 3LVQE 1MM3A 4Z0OA 5FB0A 3O47A 5E1TA 3L1XA 5FEYA 3LDYA 3MQRA 2FUIA 2LN0A 5DKAA 5C11A 4CA1A 4OGCA 3IHPA 3HCUA 4R8PK 4YBMA 3EB5A 4QQ4A 2L75A 2MUMA 1X4UA 4ZUXU 2JMDA 2F42A 4YAXA 2HDPA 2YURA 1WESA 4UP5A 2CT2A 2D8SA 5D1KB 3KQIA 1ZMSA 2FD4A 5EYAF 2YT5A 3KDEC 2YUCA 5KH9A 1CA9A 2RR4A 2Y43A 4F52B 2KE1A 1D00A 4GNFA 5I3LA 3ZVZB 1LB4A 2XP0A 2YYRA 3O37A 3FEHA 2L0BA 5C13A 2XOZA 3C6WA 4V3LC 5B79A 4I7BA 2F6NA 4A4CA 3O7AA 4GWMA 3LQJA 3QZVA 3Q1DA 1VFYA 4MSXA 4N3WA 4WZ2A 3IVVA 2KYUA 3MHHA 2G6QA 3ZTGA 4C9ZA 2KFTA 4YATA 2Y1MA 4FO9A 5B76A 3ZYQA 2MIQA 1YY6A 1V87A 2KGGA 3HSVA 2KIZA 5K3QA 4O1VA 4YBTA 2LGKA 2UZGA 2FFWA 3N9OA 2KKYA 4Q6FA 2NAAA 5G0FA 2RI7A 1D0AA 1X4IA 4LADB 4Z8MA 2XOCA 3SHBA 2CRWA 2CKLB 2CKLA 5LCWB 3SOXA 3O36A 3HQIA 2LRIC 3E2DA 3MDBC 3O33A 2LQ6A 4GWNA 4L58A 3L11A 4WA6A 3ZNIA 3FL2A 2KWNA 2CRRA 3NG2A 5FERA 4TKPB 3SOUA 2E6SA 1IYMA 1FLKA 3FM8C 4B7YC 3ZPV1 1WFKA 3U5MA 1Z2QA 1LB6A 2EODA 4LKAA 3JUEA 1LB5A 1U6GB 3KNVA 5TABA 2ECGA 4YC9A 3KV5A 2M6MA 1CHCA 4AVXA 1JOCA 2M1RA 2JMIA 4S3OB 2XOYA 2KWOA 3IVBA 2GKWA 2CSYA 1F3VB 2YSJA 2F1YA 3HCTA 1WILA 3HQMA 2CSZA 2YW8A 1MBMA 1FLLA 5J3XA 2VPEA 2XXNA 2VJEA 2VJEB 4PPEA 2RSDA 3M63A 4JJQA 2MT5A 3LJUX 1LDJB 4L7XA 4NN2A 1DVPA 3T7LA 2FSAA 4M4EA 1VYXA 1WEPA 2M3HA 1CZZA 2FUUA 3FJUB 3V43A 2QIZA 1KZZA 2L80A 5SVIA 5SVIB 2M13A 4IC3A 1WEUA 2L5UA 2XB1A 5TDRA 2LGGA 3PLWA 2QJ0A 1JM7A 1JM7B 5B8DA 1ZBDB 2ECVA 2YHOA 1QSCA 4S3OC 2KGIA 2KWKA 4FIPA 5H9MA 4GNEA 1T1HA 2VPDA 2KREA 4FK5A 3U5PA 3T9KA 1L0AA 4AP4A 3M62A 3O35A 2A25A 3O70A 5LKUA 2QICA 2LDRA
chains in the Genus database with same CATH topology
2VP7A 2HYED 2M85A 2ZETC 4WZ0A 4UP0A 4A0CD 2OXQC 2FOJA 1WEQA 3LQHA 1HYIA 1YZEA 3SOWA 2JMJA 2F1XA 1G25A 2K16A 2PUYA 4I7CA 4UI9B 2E6RA 4QF2A 5G05B 4P5OB 3U5OA 2C2LA 4KG9A 2ECNA 2YHNA 1WEOA 4YBSA 1RF3A 2FOOA 5TDWA 1WGMA 2MNZA 4XI1A 2LGLA 2BAYA 2DX8A 4R2YA 1D0JA 2F1ZA 3O34A 3T6RA 5H1TA 2LXPC 4GHUA 3HU6A 3ZPVE 1LDKC 1Z60A 4V3KC 4BHWA 4WZ3B 2K1JA 3C5KA 5D1MB 4A4BA 3HCSA 3GL6A 1WEEA 5G04B 3ZJBA 4QF3A 2JRJA 4N4FA 2LGVA 5H1UA 3L1ZB 4AYCA 4AYCB 3ZVYA 5B77A 2KU3A 2ECJA 2H0DA 2H0DB 2K4DA 2G45A 2F1WA 3N9LA 2LXHC 2C2VS 1WEMA 2MA5A 3LQIA 3MHSA 2ECTA 2YU4A 3PUQA 2YSMA 4ZQLA 3M99A 1K2FA 1D01A 3N9MA 4YADA 4GNGA 4GB0A 2VNFA 1WEVA 3RPGC 1X4JA 5JG6A 5KH7A 2F6JA 1BORA 4R7EA 3HQLA 3N9QA 3I2DA 2MD8C 2VJFA 2VJFB 5LKTA 4LLBA 2MD7B 5DINA 5B75A 4BBQA 1WIMA 2MA6A 1CA4A 2FOPA 4GNDA 3LRQA 1FBVA 3PHDA 4LK9A 4A49A 2XEUA 3HQHA 4CCGX 3KV6A 3DPLR 3GV4A 2Y1NA 2YREA 2L43A 3IVQA 2EA6A 2MNYA 3N9NA 5D1LB 2CR2A 4X3GA 2YQMA 4IC2A 5TBNA 2VPGA 2I50A 3ASLA 2VPBA 4GJHA 5H1VA 5FB1A 4YSIA 2G43A 5AIUA 4W4UA 3N9PA 3EB6A 3RPGB 2IDAA 1E4UA 3HTKC 4YABA 1WEWA 2K17A 2YQLA 4K8UA 5KH3A 2AN6A 1HYJA 4B86C 3MQSC 2LV9A 4FJCA 1CZYA 4PTBA 2PNXA 1WE9A 1XWHA 5LKXA 1FP0A 4AUQB 3PURA 5B78A 4O64A 5TRBA 4MVTA 3U5NA 1Z6UA 1N87A 2KR4A 3RTRB 4ZDTA 3VK6A 2ECWA 1MM2A 1F62A 2KWJA 1RMDA 5AITA 2ECIA 4LJNA 2EGPA 1WENA 1VD4A 5LKZA 3DQVR 4I7DA 1MM3A 5FB0A 5E1TA 3L1XA 5FEYA 3MQRA 2FUIA 2LN0A 5DKAA 5C11A 4CA1A 3IHPA 3HCUA 4R8PK 4YBMA 3EB5A 2L75A 2MUMA 1X4UA 4ZUXU 2JMDA 2F42A 4YAXA 2HDPA 2YURA 1WESA 4UP5A 2CT2A 2D8SA 5D1KB 3KQIA 1ZMSA 5EYAF 2YT5A 2YUCA 5KH9A 1CA9A 2Y43A 4F52B 2KE1A 1D00A 4GNFA 5I3LA 3ZVZB 1LB4A 2YYRA 3O37A 2L0BA 5C13A 3C6WA 4V3LC 5B79A 4I7BA 2F6NA 4A4CA 3O7AA 4GWMA 3LQJA 3QZVA 1VFYA 4MSXA 4N3WA 4WZ2A 3IVVA 2KYUA 3MHHA 2G6QA 3ZTGA 4C9ZA 2KFTA 4YATA 2Y1MA 4FO9A 5B76A 3ZYQA 2MIQA 1YY6A 1V87A 2KGGA 3HSVA 2KIZA 4O1VA 4YBTA 2LGKA 2UZGA 3N9OA 4Q6FA 2NAAA 5G0FA 2RI7A 1D0AA 1X4IA 4LADB 4Z8MA 3SHBA 2CKLB 2CKLA 5LCWB 3SOXA 3O36A 3HQIA 2LRIC 3O33A 2LQ6A 4GWNA 4L58A 3L11A 4WA6A 3ZNIA 3FL2A 2KWNA 3NG2A 5FERA 4TKPB 3SOUA 2E6SA 1IYMA 1FLKA 4B7YC 3ZPV1 1WFKA 3U5MA 1Z2QA 1LB6A 2EODA 4LKAA 1LB5A 1U6GB 3KNVA 5TABA 2ECGA 4YC9A 3KV5A 2M6MA 1CHCA 4AVXA 1JOCA 2M1RA 2JMIA 4S3OB 2KWOA 3IVBA 2GKWA 2CSYA 1F3VB 2YSJA 2F1YA 3HCTA 1WILA 3HQMA 2CSZA 2YW8A 1FLLA 5J3XA 2VPEA 2XXNA 2VJEA 2VJEB 4PPEA 2RSDA 3M63A 4JJQA 2MT5A 1LDJB 4L7XA 4NN2A 1DVPA 3T7LA 2FSAA 4M4EA 1VYXA 1WEPA 2M3HA 1CZZA 2FUUA 3V43A 2QIZA 1KZZA 2L80A 4IC3A 1WEUA 2L5UA 2XB1A 5TDRA 2LGGA 2QJ0A 1JM7A 1JM7B 5B8DA 1ZBDB 2ECVA 2YHOA 1QSCA 4S3OC 2KGIA 2KWKA 4FIPA 5H9MA 4GNEA 1T1HA 2VPDA 2KREA 4FK5A 3U5PA 1L0AA 4AP4A 3M62A 3O35A 2A25A 3O70A 5LKUA 2QICA 2LDRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2VP7 A;  2HYE D;  2M85 A;  2ZET C;  4WZ0 A;  4UP0 A;  4A0C D;  2OXQ C;  2FOJ A;  1WEQ A;  3LQH A;  1HYI A;  1YZE A;  3SOW A;  2JMJ A;  2F1X A;  1G25 A;  2K16 A;  2PUY A;  4I7C A;  4UI9 B;  2E6R A;  4QF2 A;  5G05 B;  4P5O B;  3U5O A;  2C2L A;  4KG9 A;  2ECN A;  2YHN A;  1WEO A;  4YBS A;  1RF3 A;  2FOO A;  5TDW A;  1WGM A;  2MNZ A;  4XI1 A;  2LGL A;  2BAY A;  2DX8 A;  4R2Y A;  1D0J A;  2F1Z A;  3O34 A;  3T6R A;  5H1T A;  2LXP C;  4GHU A;  3HU6 A;  3ZPV E;  1LDK C;  1Z60 A;  4V3K C;  4BHW A;  4WZ3 B;  2K1J A;  3C5K A;  5D1M B;  4A4B A;  3HCS A;  3GL6 A;  1WEE A;  5G04 B;  3ZJB A;  4QF3 A;  2JRJ A;  4N4F A;  2LGV A;  5H1U A;  3L1Z B;  4AYC A;  4AYC B;  3ZVY A;  5B77 A;  2KU3 A;  2ECJ A;  2H0D A;  2H0D B;  2K4D A;  2G45 A;  2F1W A;  3N9L A;  2LXH C;  2C2V S;  1WEM A;  2MA5 A;  3LQI A;  3MHS A;  2ECT A;  2YU4 A;  3PUQ A;  2YSM A;  4ZQL A;  3M99 A;  1K2F A;  1D01 A;  3N9M A;  4YAD A;  4GNG A;  4GB0 A;  2VNF A;  1WEV A;  3RPG C;  1X4J A;  5JG6 A;  5KH7 A;  2F6J A;  1BOR A;  4R7E A;  3HQL A;  3N9Q A;  3I2D A;  2MD8 C;  2VJF A;  2VJF B;  5LKT A;  4LLB A;  2MD7 B;  5DIN A;  5B75 A;  4BBQ A;  1WIM A;  2MA6 A;  1CA4 A;  2FOP A;  4GND A;  3LRQ A;  1FBV A;  3PHD A;  4LK9 A;  4A49 A;  2XEU A;  3HQH A;  4CCG X;  3KV6 A;  3DPL R;  3GV4 A;  2Y1N A;  2YRE A;  2L43 A;  3IVQ A;  2EA6 A;  2MNY A;  3N9N A;  5D1L B;  2CR2 A;  4X3G A;  2YQM A;  4IC2 A;  5TBN A;  2VPG A;  2I50 A;  3ASL A;  2VPB A;  4GJH A;  5H1V A;  5FB1 A;  4YSI A;  2G43 A;  5AIU A;  4W4U A;  3N9P A;  3EB6 A;  3RPG B;  2IDA A;  1E4U A;  3HTK C;  4YAB A;  1WEW A;  2K17 A;  2YQL A;  4K8U A;  5KH3 A;  2AN6 A;  1HYJ A;  4B86 C;  3MQS C;  2LV9 A;  4FJC A;  1CZY A;  4PTB A;  2PNX A;  1WE9 A;  1XWH A;  5LKX A;  1FP0 A;  4AUQ B;  3PUR A;  5B78 A;  4O64 A;  5TRB A;  4MVT A;  3U5N A;  1Z6U A;  1N87 A;  2KR4 A;  3RTR B;  4ZDT A;  3VK6 A;  2ECW A;  1MM2 A;  1F62 A;  2KWJ A;  1RMD A;  5AIT A;  2ECI A;  4LJN A;  2EGP A;  1WEN A;  1VD4 A;  5LKZ A;  3DQV R;  4I7D A;  1MM3 A;  5FB0 A;  5E1T A;  3L1X A;  5FEY A;  3MQR A;  2FUI A;  2LN0 A;  5DKA A;  5C11 A;  4CA1 A;  3IHP A;  3HCU A;  4R8P K;  4YBM A;  3EB5 A;  2L75 A;  2MUM A;  1X4U A;  4ZUX U;  2JMD A;  2F42 A;  4YAX A;  2HDP A;  2YUR A;  1WES A;  4UP5 A;  2CT2 A;  2D8S A;  5D1K B;  3KQI A;  1ZMS A;  5EYA F;  2YT5 A;  2YUC A;  5KH9 A;  1CA9 A;  2Y43 A;  4F52 B;  2KE1 A;  1D00 A;  4GNF A;  5I3L A;  3ZVZ B;  1LB4 A;  2YYR A;  3O37 A;  2L0B A;  5C13 A;  3C6W A;  4V3L C;  5B79 A;  4I7B A;  2F6N A;  4A4C A;  3O7A A;  4GWM A;  3LQJ A;  3QZV A;  1VFY A;  4MSX A;  4N3W A;  4WZ2 A;  3IVV A;  2KYU A;  3MHH A;  2G6Q A;  3ZTG A;  4C9Z A;  2KFT A;  4YAT A;  2Y1M A;  4FO9 A;  5B76 A;  3ZYQ A;  2MIQ A;  1YY6 A;  1V87 A;  2KGG A;  3HSV A;  2KIZ A;  4O1V A;  4YBT A;  2LGK A;  2UZG A;  3N9O A;  4Q6F A;  2NAA A;  5G0F A;  2RI7 A;  1D0A A;  1X4I A;  4LAD B;  4Z8M A;  3SHB A;  2CKL B;  2CKL A;  5LCW B;  3SOX A;  3O36 A;  3HQI A;  2LRI C;  3O33 A;  2LQ6 A;  4GWN A;  4L58 A;  3L11 A;  4WA6 A;  3ZNI A;  3FL2 A;  2KWN A;  3NG2 A;  5FER A;  4TKP B;  3SOU A;  2E6S A;  1IYM A;  1FLK A;  4B7Y C;  3ZPV 1;  1WFK A;  3U5M A;  1Z2Q A;  1LB6 A;  2EOD A;  4LKA A;  1LB5 A;  1U6G B;  3KNV A;  5TAB A;  2ECG A;  4YC9 A;  3KV5 A;  2M6M A;  1CHC A;  4AVX A;  1JOC A;  2M1R A;  2JMI A;  4S3O B;  2KWO A;  3IVB A;  2GKW A;  2CSY A;  1F3V B;  2YSJ A;  2F1Y A;  3HCT A;  1WIL A;  3HQM A;  2CSZ A;  2YW8 A;  1FLL A;  5J3X A;  2VPE A;  2XXN A;  2VJE A;  2VJE B;  4PPE A;  2RSD A;  3M63 A;  4JJQ A;  2MT5 A;  1LDJ B;  4L7X A;  4NN2 A;  1DVP A;  3T7L A;  2FSA A;  4M4E A;  1VYX A;  1WEP A;  2M3H A;  1CZZ A;  2FUU A;  3V43 A;  2QIZ A;  1KZZ A;  2L80 A;  4IC3 A;  1WEU A;  2L5U A;  2XB1 A;  5TDR A;  2LGG A;  2QJ0 A;  1JM7 A;  1JM7 B;  5B8D A;  1ZBD B;  2ECV A;  2YHO A;  1QSC A;  4S3O C;  2KGI A;  2KWK A;  4FIP A;  5H9M A;  4GNE A;  1T1H A;  2VPD A;  2KRE A;  4FK5 A;  3U5P A;  1L0A A;  4AP4 A;  3M62 A;  3O35 A;  2A25 A;  3O70 A;  5LKU A;  2QIC A;  2LDR A; 
#chains in the Genus database with same CATH topology
 2VP7 A;  2HYE D;  3LVR E;  3FAO A;  2M85 A;  2ZET C;  4WZ0 A;  4UP0 A;  4A0C D;  2OXQ C;  2FOJ A;  1WEQ A;  3LQH A;  1HYI A;  1YZE A;  3SOW A;  2JMJ A;  2JUN A;  4H9D A;  1DCQ A;  2F1X A;  1G25 A;  2OWA A;  2K16 A;  2E61 A;  2PUY A;  4I7C A;  4UI9 B;  2E6R A;  2B0O E;  4QF2 A;  5G05 B;  4P5O B;  3U5O A;  2JM3 A;  2C2L A;  2DJA A;  4KG9 A;  2ECN A;  2YHN A;  1WEO A;  4YBS A;  1RF3 A;  2FOO A;  5TDW A;  1WGM A;  2MNZ A;  4XI1 A;  3SUB A;  2LGL A;  2BAY A;  2DX8 A;  4R2Y A;  5SVY A;  1D0J A;  2F1Z A;  3O34 A;  3T6R A;  5H1T A;  2LXP C;  4GHU A;  3HU6 A;  3ZPV E;  1LDK C;  1Z60 A;  4V3K C;  4BHW A;  4WZ3 B;  2K1J A;  3C5K A;  5D1M B;  4A4B A;  3HCS A;  3GL6 A;  1WEE A;  5G04 B;  3ZJB A;  4QF3 A;  2JRJ A;  4N4F A;  2LGV A;  5H1U A;  3L1Z B;  4AYC A;  4AYC B;  3DWD A;  3ZVY A;  5B77 A;  2KU3 A;  2ECJ A;  2H0D A;  2H0D B;  2K4D A;  4F1P A;  2G45 A;  2F1W A;  2KKX A;  3N9L A;  2LXH C;  2L7P A;  2C2V S;  1WEM A;  2MA5 A;  3H7H A;  3LQI A;  3MHS A;  2ECT A;  2YU4 A;  3PUQ A;  2YSM A;  2IQJ A;  4ZQL A;  3M99 A;  1K2F A;  1D01 A;  3N9M A;  4YAD A;  4GNG A;  4GB0 A;  2VNF A;  1WEV A;  3RPG C;  1X4J A;  5JG6 A;  2YVR A;  5KH7 A;  2F6J A;  3FAN A;  1BOR A;  4R7E A;  3HQL A;  3N9Q A;  2CSV A;  3I2D A;  2MD8 C;  2VJF A;  2VJF B;  5LKT A;  4LLB A;  2MD7 B;  5DIN A;  5B75 A;  4BBQ A;  1WIM A;  2MA6 A;  1CA4 A;  2FOP A;  3DDT A;  4GND A;  3LRQ A;  1FBV A;  3PHD A;  4LK9 A;  2D8U A;  4A49 A;  2XEU A;  3HQH A;  2LAU A;  4CCG X;  3KV6 A;  3DPL R;  3GV4 A;  2Y1N A;  2YRE A;  2EGM A;  2L43 A;  3IVQ A;  2EA6 A;  2MNY A;  3N9N A;  5D1L B;  2CR2 A;  4X3G A;  2YQM A;  4IC2 A;  5TBN A;  2VPG A;  2I50 A;  3ASL A;  2VPB A;  4GJH A;  5H1V A;  5FB1 A;  4YSI A;  5SVX A;  2G43 A;  5AIU A;  3M7K A;  4W4U A;  3N9P A;  3EB6 A;  3RPG B;  2IDA A;  1E4U A;  3HTK C;  4YAB A;  1WEW A;  2K17 A;  2YQL A;  4K8U A;  5KH3 A;  2AN6 A;  1HYJ A;  4Z0R A;  4B86 C;  3MQS C;  2LV9 A;  4FJC A;  1CZY A;  4PTB A;  2PNX A;  1WE9 A;  1XWH A;  4OGE A;  5LKX A;  1FP0 A;  2DSM A;  4AUQ B;  3PUR A;  2P57 A;  5B78 A;  4O64 A;  5TRB A;  4MVT A;  3U5N A;  4O62 A;  1Z6U A;  1N87 A;  2KR4 A;  3RTR B;  2CON A;  4ZDT A;  3VK6 A;  2ECW A;  1MM2 A;  2EXU A;  1F62 A;  2KWJ A;  1RMD A;  5AIT A;  2ECI A;  4LJN A;  2EGP A;  1WEN A;  2MKE A;  1VD4 A;  5LKZ A;  3DQV R;  4I7D A;  3LVQ E;  1MM3 A;  4Z0O A;  5FB0 A;  3O47 A;  5E1T A;  3L1X A;  5FEY A;  3LDY A;  3MQR A;  2FUI A;  2LN0 A;  5DKA A;  5C11 A;  4CA1 A;  4OGC A;  3IHP A;  3HCU A;  4R8P K;  4YBM A;  3EB5 A;  4QQ4 A;  2L75 A;  2MUM A;  1X4U A;  4ZUX U;  2JMD A;  2F42 A;  4YAX A;  2HDP A;  2YUR A;  1WES A;  4UP5 A;  2CT2 A;  2D8S A;  5D1K B;  3KQI A;  1ZMS A;  2FD4 A;  5EYA F;  2YT5 A;  3KDE C;  2YUC A;  5KH9 A;  1CA9 A;  2RR4 A;  2Y43 A;  4F52 B;  2KE1 A;  1D00 A;  4GNF A;  5I3L A;  3ZVZ B;  1LB4 A;  2XP0 A;  2YYR A;  3O37 A;  3FEH A;  2L0B A;  5C13 A;  2XOZ A;  3C6W A;  4V3L C;  5B79 A;  4I7B A;  2F6N A;  4A4C A;  3O7A A;  4GWM A;  3LQJ A;  3QZV A;  3Q1D A;  1VFY A;  4MSX A;  4N3W A;  4WZ2 A;  3IVV A;  2KYU A;  3MHH A;  2G6Q A;  3ZTG A;  4C9Z A;  2KFT A;  4YAT A;  2Y1M A;  4FO9 A;  5B76 A;  3ZYQ A;  2MIQ A;  1YY6 A;  1V87 A;  2KGG A;  3HSV A;  2KIZ A;  5K3Q A;  4O1V A;  4YBT A;  2LGK A;  2UZG A;  2FFW A;  3N9O A;  2KKY A;  4Q6F A;  2NAA A;  5G0F A;  2RI7 A;  1D0A A;  1X4I A;  4LAD B;  4Z8M A;  2XOC A;  3SHB A;  2CRW A;  2CKL B;  2CKL A;  5LCW B;  3SOX A;  3O36 A;  3HQI A;  2LRI C;  3E2D A;  3MDB C;  3O33 A;  2LQ6 A;  4GWN A;  4L58 A;  3L11 A;  4WA6 A;  3ZNI A;  3FL2 A;  2KWN A;  2CRR A;  3NG2 A;  5FER A;  4TKP B;  3SOU A;  2E6S A;  1IYM A;  1FLK A;  3FM8 C;  4B7Y C;  3ZPV 1;  1WFK A;  3U5M A;  1Z2Q A;  1LB6 A;  2EOD A;  4LKA A;  3JUE A;  1LB5 A;  1U6G B;  3KNV A;  5TAB A;  2ECG A;  4YC9 A;  3KV5 A;  2M6M A;  1CHC A;  4AVX A;  1JOC A;  2M1R A;  2JMI A;  4S3O B;  2XOY A;  2KWO A;  3IVB A;  2GKW A;  2CSY A;  1F3V B;  2YSJ A;  2F1Y A;  3HCT A;  1WIL A;  3HQM A;  2CSZ A;  2YW8 A;  1MBM A;  1FLL A;  5J3X A;  2VPE A;  2XXN A;  2VJE A;  2VJE B;  4PPE A;  2RSD A;  3M63 A;  4JJQ A;  2MT5 A;  3LJU X;  1LDJ B;  4L7X A;  4NN2 A;  1DVP A;  3T7L A;  2FSA A;  4M4E A;  1VYX A;  1WEP A;  2M3H A;  1CZZ A;  2FUU A;  3FJU B;  3V43 A;  2QIZ A;  1KZZ A;  2L80 A;  5SVI A;  5SVI B;  2M13 A;  4IC3 A;  1WEU A;  2L5U A;  2XB1 A;  5TDR A;  2LGG A;  3PLW A;  2QJ0 A;  1JM7 A;  1JM7 B;  5B8D A;  1ZBD B;  2ECV A;  2YHO A;  1QSC A;  4S3O C;  2KGI A;  2KWK A;  4FIP A;  5H9M A;  4GNE A;  1T1H A;  2VPD A;  2KRE A;  4FK5 A;  3U5P A;  3T9K A;  1L0A A;  4AP4 A;  3M62 A;  3O35 A;  2A25 A;  3O70 A;  5LKU A;  2QIC A;  2LDR A; 
#chains in the Genus database with same CATH homology
 2VP7 A;  2HYE D;  2M85 A;  2ZET C;  4WZ0 A;  4UP0 A;  4A0C D;  2OXQ C;  2FOJ A;  1WEQ A;  3LQH A;  1HYI A;  1YZE A;  3SOW A;  2JMJ A;  2F1X A;  1G25 A;  2K16 A;  2PUY A;  4I7C A;  4UI9 B;  2E6R A;  4QF2 A;  5G05 B;  4P5O B;  3U5O A;  2C2L A;  4KG9 A;  2ECN A;  2YHN A;  1WEO A;  4YBS A;  1RF3 A;  2FOO A;  5TDW A;  1WGM A;  2MNZ A;  4XI1 A;  2LGL A;  2BAY A;  2DX8 A;  4R2Y A;  1D0J A;  2F1Z A;  3O34 A;  3T6R A;  5H1T A;  2LXP C;  4GHU A;  3HU6 A;  3ZPV E;  1LDK C;  1Z60 A;  4V3K C;  4BHW A;  4WZ3 B;  2K1J A;  3C5K A;  5D1M B;  4A4B A;  3HCS A;  3GL6 A;  1WEE A;  5G04 B;  3ZJB A;  4QF3 A;  2JRJ A;  4N4F A;  2LGV A;  5H1U A;  3L1Z B;  4AYC A;  4AYC B;  3ZVY A;  5B77 A;  2KU3 A;  2ECJ A;  2H0D A;  2H0D B;  2K4D A;  2G45 A;  2F1W A;  3N9L A;  2LXH C;  2C2V S;  1WEM A;  2MA5 A;  3LQI A;  3MHS A;  2ECT A;  2YU4 A;  3PUQ A;  2YSM A;  4ZQL A;  3M99 A;  1K2F A;  1D01 A;  3N9M A;  4YAD A;  4GNG A;  4GB0 A;  2VNF A;  1WEV A;  3RPG C;  1X4J A;  5JG6 A;  5KH7 A;  2F6J A;  1BOR A;  4R7E A;  3HQL A;  3N9Q A;  3I2D A;  2MD8 C;  2VJF A;  2VJF B;  5LKT A;  4LLB A;  2MD7 B;  5DIN A;  5B75 A;  4BBQ A;  1WIM A;  2MA6 A;  1CA4 A;  2FOP A;  4GND A;  3LRQ A;  1FBV A;  3PHD A;  4LK9 A;  4A49 A;  2XEU A;  3HQH A;  4CCG X;  3KV6 A;  3DPL R;  3GV4 A;  2Y1N A;  2YRE A;  2L43 A;  3IVQ A;  2EA6 A;  2MNY A;  3N9N A;  5D1L B;  2CR2 A;  4X3G A;  2YQM A;  4IC2 A;  5TBN A;  2VPG A;  2I50 A;  3ASL A;  2VPB A;  4GJH A;  5H1V A;  5FB1 A;  4YSI A;  2G43 A;  5AIU A;  4W4U A;  3N9P A;  3EB6 A;  3RPG B;  2IDA A;  1E4U A;  3HTK C;  4YAB A;  1WEW A;  2K17 A;  2YQL A;  4K8U A;  5KH3 A;  2AN6 A;  1HYJ A;  4B86 C;  3MQS C;  2LV9 A;  4FJC A;  1CZY A;  4PTB A;  2PNX A;  1WE9 A;  1XWH A;  5LKX A;  1FP0 A;  4AUQ B;  3PUR A;  5B78 A;  4O64 A;  5TRB A;  4MVT A;  3U5N A;  1Z6U A;  1N87 A;  2KR4 A;  3RTR B;  4ZDT A;  3VK6 A;  2ECW A;  1MM2 A;  1F62 A;  2KWJ A;  1RMD A;  5AIT A;  2ECI A;  4LJN A;  2EGP A;  1WEN A;  1VD4 A;  5LKZ A;  3DQV R;  4I7D A;  1MM3 A;  5FB0 A;  5E1T A;  3L1X A;  5FEY A;  3MQR A;  2FUI A;  2LN0 A;  5DKA A;  5C11 A;  4CA1 A;  3IHP A;  3HCU A;  4R8P K;  4YBM A;  3EB5 A;  2L75 A;  2MUM A;  1X4U A;  4ZUX U;  2JMD A;  2F42 A;  4YAX A;  2HDP A;  2YUR A;  1WES A;  4UP5 A;  2CT2 A;  2D8S A;  5D1K B;  3KQI A;  1ZMS A;  5EYA F;  2YT5 A;  2YUC A;  5KH9 A;  1CA9 A;  2Y43 A;  4F52 B;  2KE1 A;  1D00 A;  4GNF A;  5I3L A;  3ZVZ B;  1LB4 A;  2YYR A;  3O37 A;  2L0B A;  5C13 A;  3C6W A;  4V3L C;  5B79 A;  4I7B A;  2F6N A;  4A4C A;  3O7A A;  4GWM A;  3LQJ A;  3QZV A;  1VFY A;  4MSX A;  4N3W A;  4WZ2 A;  3IVV A;  2KYU A;  3MHH A;  2G6Q A;  3ZTG A;  4C9Z A;  2KFT A;  4YAT A;  2Y1M A;  4FO9 A;  5B76 A;  3ZYQ A;  2MIQ A;  1YY6 A;  1V87 A;  2KGG A;  3HSV A;  2KIZ A;  4O1V A;  4YBT A;  2LGK A;  2UZG A;  3N9O A;  4Q6F A;  2NAA A;  5G0F A;  2RI7 A;  1D0A A;  1X4I A;  4LAD B;  4Z8M A;  3SHB A;  2CKL B;  2CKL A;  5LCW B;  3SOX A;  3O36 A;  3HQI A;  2LRI C;  3O33 A;  2LQ6 A;  4GWN A;  4L58 A;  3L11 A;  4WA6 A;  3ZNI A;  3FL2 A;  2KWN A;  3NG2 A;  5FER A;  4TKP B;  3SOU A;  2E6S A;  1IYM A;  1FLK A;  4B7Y C;  3ZPV 1;  1WFK A;  3U5M A;  1Z2Q A;  1LB6 A;  2EOD A;  4LKA A;  1LB5 A;  1U6G B;  3KNV A;  5TAB A;  2ECG A;  4YC9 A;  3KV5 A;  2M6M A;  1CHC A;  4AVX A;  1JOC A;  2M1R A;  2JMI A;  4S3O B;  2KWO A;  3IVB A;  2GKW A;  2CSY A;  1F3V B;  2YSJ A;  2F1Y A;  3HCT A;  1WIL A;  3HQM A;  2CSZ A;  2YW8 A;  1FLL A;  5J3X A;  2VPE A;  2XXN A;  2VJE A;  2VJE B;  4PPE A;  2RSD A;  3M63 A;  4JJQ A;  2MT5 A;  1LDJ B;  4L7X A;  4NN2 A;  1DVP A;  3T7L A;  2FSA A;  4M4E A;  1VYX A;  1WEP A;  2M3H A;  1CZZ A;  2FUU A;  3V43 A;  2QIZ A;  1KZZ A;  2L80 A;  4IC3 A;  1WEU A;  2L5U A;  2XB1 A;  5TDR A;  2LGG A;  2QJ0 A;  1JM7 A;  1JM7 B;  5B8D A;  1ZBD B;  2ECV A;  2YHO A;  1QSC A;  4S3O C;  2KGI A;  2KWK A;  4FIP A;  5H9M A;  4GNE A;  1T1H A;  2VPD A;  2KRE A;  4FK5 A;  3U5P A;  1L0A A;  4AP4 A;  3M62 A;  3O35 A;  2A25 A;  3O70 A;  5LKU A;  2QIC A;  2LDR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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