1K2FA

Siah, seven in absentia homolog
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
190
structure length
190
Chain Sequence
SVLFPCKYASSGCEITLPHTEKAEHEELCEFRPYSCPCPGASCKWQGSLDAVMPHLMHQHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGFHFMLVLEKQEKYDGHQQFFAIVQLIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHEGIATAIMNSDCLVFDTSIAQLFAENGNLGINVTISMC
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Siah ubiquitin ligase is structurally related to TRAF and modulates TNF-alpha signaling.
pubmed doi rcsb
molecule keywords siah-1A protein
molecule tags Ligase, protein binding
source organism Mus musculus
total genus 39
structure length 190
sequence length 190
chains with identical sequence B
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2001-09-26
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.210.10 Mainly Beta Sandwich Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A 1k2fA01
3.30.40.10 Alpha Beta 2-Layer Sandwich Herpes Virus-1 Zinc/RING finger domain, C3HC4 (zinc finger) 1k2fA02
2LGVA 3MHHA 3L1ZB 1FP0A 2LN0A 2K4DA 1WESA 2M3HA 2KWOA 3ZPV1 2F6NA 2JMJA 3FL2A 1FLLA 2XB1A 3LQIA 2G43A 3MQRA 1T1HA 1BORA 3N9PA 3GV4A 4QF2A 2FUUA 2CKLB 4UP5A 5TABA 2CKLA 4GB0A 5FEYA 3RPGB 3KV5A 4AP4A 2KU3A 1WEVA 4V3LC 2MNYA 5G04B 4A4CA 2BAYA 4AUQB 1CZZA 4NN2A 3O35A 3N9NA 2EODA 5H1VA 1Z2QA 4YABA 4B7YC 5B8DA 3QZVA 2DX8A 2LV9A 2UZGA 4WA6A 1V87A 1WEMA 3DPLR 4W4UA 4GJHA 4KG9A 4LADB 4WZ0A 5H1TA 3L11A 3L1XA 2C2VS 1WFKA 1LDKC 4GNGA 5B75A 1FLKA 4UP0A 3HCTA 2EA6A 1K2FA 3IVBA 4QF3A 4GWMA 2GKWA 3VK6A 3U5NA 4YBMA 4ZUXU 2F42A 4UI9B 3MQSC 3RTRB 3V43A 2JMDA 1ZBDB 3IVQA 2YT5A 2L0BA 4XI1A 3PHDA 1KZZA 2F1WA 2FOJA 1VYXA 2CT2A 4JJQA 2MD8C 4CCGX 5EYAF 3N9QA 3IVVA 2MA6A 4Z8MA 1F62A 2E6SA 3O37A 2YHNA 5D1LB 2LDRA 2ECIA 5AITA 3U5OA 4CA1A 2E6RA 4BBQA 3ZPVE 3T7LA 4N4FA 2LGGA 1LDJB 4YATA 4S3OC 4B86C 3IHPA 2D8SA 2KGIA 2F6JA 2MUMA 4V3KC 1DVPA 2JRJA 3LRQA 3SOUA 2ECNA 4AVXA 2LXHC 2YSMA 4F52B 4PPEA 4FK5A 2KWNA 4BHWA 1L0AA 4A0CD 2AN6A 4YAXA 1WIMA 5DINA 1U6GB 1WEQA 2JMIA 1WE9A 2YW8A 3N9MA 2YREA 1QSCA 5KH9A 5TRBA 2VPGA 5TDWA 3HTKC 2MA5A 1FBVA 1WEOA 1CA4A 2F1XA 2VP7A 4YSIA 5LKZA 1WILA 2YYRA 4X3GA 1ZMSA 2YUCA 4GNDA 1E4UA 2NAAA 2XEUA 5TDRA 2CR2A 1VD4A 2RSDA 2QIZA 2KWKA 3DQVR 4R8PK 1YY6A 2FOOA 3EB5A 1WENA 1WGMA 2G6QA 2CSYA 2FSAA 5KH3A 3SHBA 2VPBA 4FJCA 2LGLA 4GHUA 3MHSA 5D1MB 3HQMA 2VJFA 2KGGA 3ZNIA 2L43A 1RF3A 4A4BA 1MM2A 1N87A 4YBSA 1WEEA 2CSZA 1JM7B 1LB5A 3KNVA 4YC9A 1JM7A 2MNZA 3ZVYA 4S3OB 5LKTA 2YURA 2KWJA 4YBTA 3HCUA 3SOXA 5AIUA 1Z6UA 3C6WA 3O34A 1CZYA 2LQ6A 3HQLA 2Y1NA 5I3LA 3O36A 5H1UA 5LKXA 1D01A 4GWNA 3ASLA 2EGPA 2C2LA 2L5UA 2Y43A 1IYMA 4GNFA 3N9LA 2KIZA 2HDPA 2F1YA 4P5OB 3N9OA 3HQHA 5B78A 3O70A 2M1RA 4FO9A 4R2YA 4A49A 4L58A 2MIQA 1D0AA 2QICA 2YQMA 3GL6A 2LXPC 2K17A 3HCSA 1HYJA 1X4JA 4YADA 4N3WA 2H0DB 4GNEA 2ECJA 2KREA 2MD7B 4I7CA 4I7BA 2H0DA 3M99A 5KH7A 3C5KA 2FOPA 2K1JA 3ZYQA 4M4EA 3KV6A 3LQJA 2ECTA 3M62A 1D0JA 4ZQLA 1Z60A 5B76A 1CHCA 3O7AA 4O1VA 5H9MA 3HU6A 1VFYA 2G45A 5FB1A 2XXNA 2M6MA 2MT5A 2ECVA 2OXQC 2A25A 2ECGA 2RI7A 1F3VB 3ZJBA 2YHOA 4LJNA 2VNFA 2L75A 3EB6A 5E1TA 1HYIA 2VJFB 1XWHA 4C9ZA 4ZDTA 5FB0A 2KE1A 2PUYA 1YZEA 2I50A 2QJ0A 2Y1MA 4L7XA 3LQHA 5LCWB 5TBNA 1X4IA 5LKUA 5B79A 3U5MA 3HQIA 5DKAA 2KR4A 2ECWA 2VJEB 1LB6A 4MSXA 3T6RA 5G05B 2VJEA 5D1KB 4FIPA 2KFTA 4IC3A 5B77A 3U5PA 4PTBA 1CA9A 1G25A 1WEUA 3ZVZB 4AYCB 2LGKA 3NG2A 2YU4A 4I7DA 4R7EA 5G0FA 3RPGC 4AYCA 4WZ2A 5FERA 2YQLA 2IDAA 2HYED 4MVTA 2FUIA 3PURA 4LK9A 1JOCA 4O64A 4TKPB 2L80A 2KYUA 4IC2A 4Q6FA 5J3XA 3I2DA 2YSJA 3HSVA 1LB4A 2K16A 1X4UA 3KQIA 4LKAA 2VPEA 2PNXA 3PUQA 4LLBA 1WEWA 2LRIC 2VPDA 5C11A 5C13A 5JG6A 2F1ZA 1WEPA 3M63A 4WZ3B 1D00A 1MM3A 2ZETC 3ZTGA 4K8UA 2M85A 1RMDA 3SOWA 3O33A
chains in the Genus database with same CATH superfamily
2LGVA 3MHHA 3L1ZB 1FP0A 2LN0A 2K4DA 4O62A 4Z0OA 1WESA 2OWAA 2M3HA 2E61A 2KWOA 3ZPV1 2F6NA 2JMJA 3FL2A 1FLLA 2XB1A 3LQIA 2G43A 3MQRA 1T1HA 1BORA 5SVYA 3N9PA 2XOYA 3GV4A 4QF2A 2FUUA 2CKLB 4UP5A 5TABA 2CKLA 1DCQA 4GB0A 5FEYA 2CONA 3RPGB 3KV5A 1MBMA 3E2DA 4AP4A 2KU3A 1WEVA 4V3LC 2MNYA 5G04B 4A4CA 2BAYA 4AUQB 1CZZA 2JM3A 5SVIA 4NN2A 3O35A 3N9NA 2EODA 5H1VA 1Z2QA 3SUBA 2D8UA 4YABA 4B7YC 5B8DA 3QZVA 2DX8A 2LV9A 2UZGA 4WA6A 1V87A 1WEMA 3DPLR 4W4UA 4GJHA 4KG9A 4LADB 3T9KA 4WZ0A 5H1TA 3L11A 3L1XA 2C2VS 1WFKA 1LDKC 4GNGA 5B75A 1FLKA 4UP0A 3HCTA 2EA6A 1K2FA 3IVBA 5K3QA 4QF3A 4GWMA 2GKWA 3VK6A 3U5NA 4YBMA 2CRWA 4ZUXU 2F42A 4UI9B 3MQSC 3RTRB 3V43A 2JMDA 1ZBDB 3IVQA 2YT5A 2L0BA 4XI1A 3PHDA 1KZZA 2F1WA 2FOJA 1VYXA 2CT2A 4JJQA 2MD8C 4CCGX 5EYAF 3N9QA 3IVVA 3M7KA 2MA6A 4Z8MA 1F62A 2EGMA 2E6SA 3O37A 2YHNA 5D1LB 2LDRA 2ECIA 3PLWA 3DDTA 5AITA 3U5OA 4CA1A 2E6RA 4BBQA 3ZPVE 3T7LA 4N4FA 2LGGA 1LDJB 4YATA 4H9DA 4S3OC 4B86C 3IHPA 2D8SA 2KGIA 2DSMA 2F6JA 2MUMA 3Q1DA 4V3KC 1DVPA 2JRJA 3LRQA 3SOUA 2ECNA 4AVXA 2LXHC 2YSMA 4F52B 4PPEA 4Z0RA 4FK5A 2KWNA 4BHWA 1L0AA 4A0CD 2AN6A 4YAXA 1WIMA 5DINA 1U6GB 1WEQA 2JMIA 1WE9A 2YW8A 3N9MA 2YVRA 2YREA 1QSCA 5KH9A 5TRBA 2VPGA 5TDWA 3HTKC 2MA5A 1FBVA 1WEOA 1CA4A 2F1XA 2CSVA 2VP7A 4YSIA 5LKZA 1WILA 2YYRA 4X3GA 1ZMSA 5SVIB 2YUCA 4GNDA 1E4UA 2NAAA 2XEUA 5TDRA 2CR2A 2XOCA 1VD4A 2RSDA 2QIZA 4OGEA 2KWKA 3FJUB 3DQVR 5SVXA 4R8PK 1YY6A 2FOOA 3EB5A 3FAOA 1WENA 1WGMA 2G6QA 2P57A 2CSYA 2FSAA 5KH3A 3SHBA 2VPBA 4FJCA 2LGLA 4GHUA 3MHSA 5D1MB 3HQMA 2VJFA 2KGGA 3ZNIA 2L43A 1RF3A 4A4BA 1MM2A 2IQJA 1N87A 4YBSA 1WEEA 2CSZA 1JM7B 3KDEC 1LB5A 3KNVA 4YC9A 1JM7A 2MNZA 3ZVYA 4S3OB 5LKTA 2KKXA 2YURA 2KWJA 2EXUA 4YBTA 3HCUA 3SOXA 5AIUA 1Z6UA 3C6WA 3O34A 1CZYA 2LQ6A 3HQLA 2Y1NA 5I3LA 3O36A 5H1UA 5LKXA 1D01A 4GWNA 3ASLA 2EGPA 2C2LA 2L5UA 2M13A 3LJUX 2Y43A 1IYMA 4GNFA 3N9LA 2KIZA 2HDPA 2F1YA 4P5OB 3N9OA 3HQHA 5B78A 3O70A 2M1RA 4FO9A 4R2YA 2JUNA 4L58A 2MIQA 4A49A 1D0AA 2QICA 2YQMA 3GL6A 2LXPC 2K17A 2MKEA 3HCSA 1HYJA 1X4JA 4YADA 4N3WA 2H0DB 4GNEA 2ECJA 2KREA 2MD7B 4I7CA 4I7BA 2H0DA 3M99A 5KH7A 3C5KA 2FOPA 2K1JA 2B0OE 3ZYQA 2XOZA 4M4EA 3KV6A 3LQJA 2ECTA 3M62A 1D0JA 2LAUA 4ZQLA 3JUEA 4F1PA 1Z60A 5B76A 1CHCA 3O7AA 4O1VA 5H9MA 3HU6A 1VFYA 2G45A 4OGCA 5FB1A 2XXNA 2M6MA 2MT5A 2ECVA 2OXQC 2A25A 2ECGA 3LVQE 2RI7A 1F3VB 3ZJBA 2YHOA 4LJNA 2VNFA 2L75A 2FFWA 3EB6A 5E1TA 1HYIA 2VJFB 1XWHA 4C9ZA 4ZDTA 5FB0A 2KE1A 2PUYA 1YZEA 2I50A 2DJAA 2QJ0A 2Y1MA 4L7XA 3LQHA 5LCWB 5TBNA 1X4IA 5LKUA 5B79A 3U5MA 3HQIA 5DKAA 2KR4A 2ECWA 2VJEB 1LB6A 4MSXA 3H7HA 3T6RA 2XP0A 5G05B 2VJEA 5D1KB 4FIPA 2KFTA 4IC3A 5B77A 3U5PA 4PTBA 1CA9A 3FEHA 1G25A 1WEUA 3FM8C 3ZVZB 4AYCB 2LGKA 3NG2A 2KKYA 2YU4A 4I7DA 4R7EA 5G0FA 3RPGC 4AYCA 4WZ2A 5FERA 2YQLA 2IDAA 2HYED 4MVTA 2FUIA 2RR4A 3PURA 4LK9A 1JOCA 4O64A 4TKPB 3LDYA 2L80A 2KYUA 4IC2A 2CRRA 4Q6FA 5J3XA 2L7PA 2FD4A 3I2DA 3LVRE 2YSJA 3O47A 3HSVA 1LB4A 2K16A 1X4UA 3KQIA 3MDBC 4LKAA 2VPEA 2PNXA 3PUQA 4LLBA 1WEWA 2LRIC 2VPDA 5C11A 5C13A 5JG6A 2F1ZA 1WEPA 3M63A 4QQ4A 4WZ3B 1D00A 1MM3A 2ZETC 3FANA 3ZTGA 4K8UA 2M85A 1RMDA 3SOWA 3DWDA 3O33A
chains in the Genus database with same CATH topology
2LGVA 3MHHA 3L1ZB 1FP0A 2LN0A 2K4DA 1WESA 2M3HA 2KWOA 3ZPV1 2F6NA 2JMJA 3FL2A 1FLLA 2XB1A 3LQIA 2G43A 3MQRA 1T1HA 1BORA 3N9PA 3GV4A 4QF2A 2FUUA 2CKLB 4UP5A 5TABA 2CKLA 4GB0A 5FEYA 3RPGB 3KV5A 4AP4A 2KU3A 1WEVA 4V3LC 2MNYA 5G04B 4A4CA 2BAYA 4AUQB 1CZZA 4NN2A 3O35A 3N9NA 2EODA 5H1VA 1Z2QA 4YABA 4B7YC 5B8DA 3QZVA 2DX8A 2LV9A 2UZGA 4WA6A 1V87A 1WEMA 3DPLR 4W4UA 4GJHA 4KG9A 4LADB 4WZ0A 5H1TA 3L11A 3L1XA 2C2VS 1WFKA 1LDKC 4GNGA 5B75A 1FLKA 4UP0A 3HCTA 2EA6A 1K2FA 3IVBA 4QF3A 4GWMA 2GKWA 3VK6A 3U5NA 4YBMA 4ZUXU 2F42A 4UI9B 3MQSC 3RTRB 3V43A 2JMDA 1ZBDB 3IVQA 2YT5A 2L0BA 4XI1A 3PHDA 1KZZA 2F1WA 2FOJA 1VYXA 2CT2A 4JJQA 2MD8C 4CCGX 5EYAF 3N9QA 3IVVA 2MA6A 4Z8MA 1F62A 2E6SA 3O37A 2YHNA 5D1LB 2LDRA 2ECIA 5AITA 3U5OA 4CA1A 2E6RA 4BBQA 3ZPVE 3T7LA 4N4FA 2LGGA 1LDJB 4YATA 4S3OC 4B86C 3IHPA 2D8SA 2KGIA 2F6JA 2MUMA 4V3KC 1DVPA 2JRJA 3LRQA 3SOUA 2ECNA 4AVXA 2LXHC 2YSMA 4F52B 4PPEA 4FK5A 2KWNA 4BHWA 1L0AA 4A0CD 2AN6A 4YAXA 1WIMA 5DINA 1U6GB 1WEQA 2JMIA 1WE9A 2YW8A 3N9MA 2YREA 1QSCA 5KH9A 5TRBA 2VPGA 5TDWA 3HTKC 2MA5A 1FBVA 1WEOA 1CA4A 2F1XA 2VP7A 4YSIA 5LKZA 1WILA 2YYRA 4X3GA 1ZMSA 2YUCA 4GNDA 1E4UA 2NAAA 2XEUA 5TDRA 2CR2A 1VD4A 2RSDA 2QIZA 2KWKA 3DQVR 4R8PK 1YY6A 2FOOA 3EB5A 1WENA 1WGMA 2G6QA 2CSYA 2FSAA 5KH3A 3SHBA 2VPBA 4FJCA 2LGLA 4GHUA 3MHSA 5D1MB 3HQMA 2VJFA 2KGGA 3ZNIA 2L43A 1RF3A 4A4BA 1MM2A 1N87A 4YBSA 1WEEA 2CSZA 1JM7B 1LB5A 3KNVA 4YC9A 1JM7A 2MNZA 3ZVYA 4S3OB 5LKTA 2YURA 2KWJA 4YBTA 3HCUA 3SOXA 5AIUA 1Z6UA 3C6WA 3O34A 1CZYA 2LQ6A 3HQLA 2Y1NA 5I3LA 3O36A 5H1UA 5LKXA 1D01A 4GWNA 3ASLA 2EGPA 2C2LA 2L5UA 2Y43A 1IYMA 4GNFA 3N9LA 2KIZA 2HDPA 2F1YA 4P5OB 3N9OA 3HQHA 5B78A 3O70A 2M1RA 4FO9A 4R2YA 4A49A 4L58A 2MIQA 1D0AA 2QICA 2YQMA 3GL6A 2LXPC 2K17A 3HCSA 1HYJA 1X4JA 4YADA 4N3WA 2H0DB 4GNEA 2ECJA 2KREA 2MD7B 4I7CA 4I7BA 2H0DA 3M99A 5KH7A 3C5KA 2FOPA 2K1JA 3ZYQA 4M4EA 3KV6A 3LQJA 2ECTA 3M62A 1D0JA 4ZQLA 1Z60A 5B76A 1CHCA 3O7AA 4O1VA 5H9MA 3HU6A 1VFYA 2G45A 5FB1A 2XXNA 2M6MA 2MT5A 2ECVA 2OXQC 2A25A 2ECGA 2RI7A 1F3VB 3ZJBA 2YHOA 4LJNA 2VNFA 2L75A 3EB6A 5E1TA 1HYIA 2VJFB 1XWHA 4C9ZA 4ZDTA 5FB0A 2KE1A 2PUYA 1YZEA 2I50A 2QJ0A 2Y1MA 4L7XA 3LQHA 5LCWB 5TBNA 1X4IA 5LKUA 5B79A 3U5MA 3HQIA 5DKAA 2KR4A 2ECWA 2VJEB 1LB6A 4MSXA 3T6RA 5G05B 2VJEA 5D1KB 4FIPA 2KFTA 4IC3A 5B77A 3U5PA 4PTBA 1CA9A 1G25A 1WEUA 3ZVZB 4AYCB 2LGKA 3NG2A 2YU4A 4I7DA 4R7EA 5G0FA 3RPGC 4AYCA 4WZ2A 5FERA 2YQLA 2IDAA 2HYED 4MVTA 2FUIA 3PURA 4LK9A 1JOCA 4O64A 4TKPB 2L80A 2KYUA 4IC2A 4Q6FA 5J3XA 3I2DA 2YSJA 3HSVA 1LB4A 2K16A 1X4UA 3KQIA 4LKAA 2VPEA 2PNXA 3PUQA 4LLBA 1WEWA 2LRIC 2VPDA 5C11A 5C13A 5JG6A 2F1ZA 1WEPA 3M63A 4WZ3B 1D00A 1MM3A 2ZETC 3ZTGA 4K8UA 2M85A 1RMDA 3SOWA 3O33A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2LGV A;  3MHH A;  3L1Z B;  1FP0 A;  2LN0 A;  2K4D A;  1WES A;  2M3H A;  2KWO A;  3ZPV 1;  2F6N A;  2JMJ A;  3FL2 A;  1FLL A;  2XB1 A;  3LQI A;  2G43 A;  3MQR A;  1T1H A;  1BOR A;  3N9P A;  3GV4 A;  4QF2 A;  2FUU A;  2CKL B;  4UP5 A;  5TAB A;  2CKL A;  4GB0 A;  5FEY A;  3RPG B;  3KV5 A;  4AP4 A;  2KU3 A;  1WEV A;  4V3L C;  2MNY A;  5G04 B;  4A4C A;  2BAY A;  4AUQ B;  1CZZ A;  4NN2 A;  3O35 A;  3N9N A;  2EOD A;  5H1V A;  1Z2Q A;  4YAB A;  4B7Y C;  5B8D A;  3QZV A;  2DX8 A;  2LV9 A;  2UZG A;  4WA6 A;  1V87 A;  1WEM A;  3DPL R;  4W4U A;  4GJH A;  4KG9 A;  4LAD B;  4WZ0 A;  5H1T A;  3L11 A;  3L1X A;  2C2V S;  1WFK A;  1LDK C;  4GNG A;  5B75 A;  1FLK A;  4UP0 A;  3HCT A;  2EA6 A;  1K2F A;  3IVB A;  4QF3 A;  4GWM A;  2GKW A;  3VK6 A;  3U5N A;  4YBM A;  4ZUX U;  2F42 A;  4UI9 B;  3MQS C;  3RTR B;  3V43 A;  2JMD A;  1ZBD B;  3IVQ A;  2YT5 A;  2L0B A;  4XI1 A;  3PHD A;  1KZZ A;  2F1W A;  2FOJ A;  1VYX A;  2CT2 A;  4JJQ A;  2MD8 C;  4CCG X;  5EYA F;  3N9Q A;  3IVV A;  2MA6 A;  4Z8M A;  1F62 A;  2E6S A;  3O37 A;  2YHN A;  5D1L B;  2LDR A;  2ECI A;  5AIT A;  3U5O A;  4CA1 A;  2E6R A;  4BBQ A;  3ZPV E;  3T7L A;  4N4F A;  2LGG A;  1LDJ B;  4YAT A;  4S3O C;  4B86 C;  3IHP A;  2D8S A;  2KGI A;  2F6J A;  2MUM A;  4V3K C;  1DVP A;  2JRJ A;  3LRQ A;  3SOU A;  2ECN A;  4AVX A;  2LXH C;  2YSM A;  4F52 B;  4PPE A;  4FK5 A;  2KWN A;  4BHW A;  1L0A A;  4A0C D;  2AN6 A;  4YAX A;  1WIM A;  5DIN A;  1U6G B;  1WEQ A;  2JMI A;  1WE9 A;  2YW8 A;  3N9M A;  2YRE A;  1QSC A;  5KH9 A;  5TRB A;  2VPG A;  5TDW A;  3HTK C;  2MA5 A;  1FBV A;  1WEO A;  1CA4 A;  2F1X A;  2VP7 A;  4YSI A;  5LKZ A;  1WIL A;  2YYR A;  4X3G A;  1ZMS A;  2YUC A;  4GND A;  1E4U A;  2NAA A;  2XEU A;  5TDR A;  2CR2 A;  1VD4 A;  2RSD A;  2QIZ A;  2KWK A;  3DQV R;  4R8P K;  1YY6 A;  2FOO A;  3EB5 A;  1WEN A;  1WGM A;  2G6Q A;  2CSY A;  2FSA A;  5KH3 A;  3SHB A;  2VPB A;  4FJC A;  2LGL A;  4GHU A;  3MHS A;  5D1M B;  3HQM A;  2VJF A;  2KGG A;  3ZNI A;  2L43 A;  1RF3 A;  4A4B A;  1MM2 A;  1N87 A;  4YBS A;  1WEE A;  2CSZ A;  1JM7 B;  1LB5 A;  3KNV A;  4YC9 A;  1JM7 A;  2MNZ A;  3ZVY A;  4S3O B;  5LKT A;  2YUR A;  2KWJ A;  4YBT A;  3HCU A;  3SOX A;  5AIU A;  1Z6U A;  3C6W A;  3O34 A;  1CZY A;  2LQ6 A;  3HQL A;  2Y1N A;  5I3L A;  3O36 A;  5H1U A;  5LKX A;  1D01 A;  4GWN A;  3ASL A;  2EGP A;  2C2L A;  2L5U A;  2Y43 A;  1IYM A;  4GNF A;  3N9L A;  2KIZ A;  2HDP A;  2F1Y A;  4P5O B;  3N9O A;  3HQH A;  5B78 A;  3O70 A;  2M1R A;  4FO9 A;  4R2Y A;  4A49 A;  4L58 A;  2MIQ A;  1D0A A;  2QIC A;  2YQM A;  3GL6 A;  2LXP C;  2K17 A;  3HCS A;  1HYJ A;  1X4J A;  4YAD A;  4N3W A;  2H0D B;  4GNE A;  2ECJ A;  2KRE A;  2MD7 B;  4I7C A;  4I7B A;  2H0D A;  3M99 A;  5KH7 A;  3C5K A;  2FOP A;  2K1J A;  3ZYQ A;  4M4E A;  3KV6 A;  3LQJ A;  2ECT A;  3M62 A;  1D0J A;  4ZQL A;  1Z60 A;  5B76 A;  1CHC A;  3O7A A;  4O1V A;  5H9M A;  3HU6 A;  1VFY A;  2G45 A;  5FB1 A;  2XXN A;  2M6M A;  2MT5 A;  2ECV A;  2OXQ C;  2A25 A;  2ECG A;  2RI7 A;  1F3V B;  3ZJB A;  2YHO A;  4LJN A;  2VNF A;  2L75 A;  3EB6 A;  5E1T A;  1HYI A;  2VJF B;  1XWH A;  4C9Z A;  4ZDT A;  5FB0 A;  2KE1 A;  2PUY A;  1YZE A;  2I50 A;  2QJ0 A;  2Y1M A;  4L7X A;  3LQH A;  5LCW B;  5TBN A;  1X4I A;  5LKU A;  5B79 A;  3U5M A;  3HQI A;  5DKA A;  2KR4 A;  2ECW A;  2VJE B;  1LB6 A;  4MSX A;  3T6R A;  5G05 B;  2VJE A;  5D1K B;  4FIP A;  2KFT A;  4IC3 A;  5B77 A;  3U5P A;  4PTB A;  1CA9 A;  1G25 A;  1WEU A;  3ZVZ B;  4AYC B;  2LGK A;  3NG2 A;  2YU4 A;  4I7D A;  4R7E A;  5G0F A;  3RPG C;  4AYC A;  4WZ2 A;  5FER A;  2YQL A;  2IDA A;  2HYE D;  4MVT A;  2FUI A;  3PUR A;  4LK9 A;  1JOC A;  4O64 A;  4TKP B;  2L80 A;  2KYU A;  4IC2 A;  4Q6F A;  5J3X A;  3I2D A;  2YSJ A;  3HSV A;  1LB4 A;  2K16 A;  1X4U A;  3KQI A;  4LKA A;  2VPE A;  2PNX A;  3PUQ A;  4LLB A;  1WEW A;  2LRI C;  2VPD A;  5C11 A;  5C13 A;  5JG6 A;  2F1Z A;  1WEP A;  3M63 A;  4WZ3 B;  1D00 A;  1MM3 A;  2ZET C;  3ZTG A;  4K8U A;  2M85 A;  1RMD A;  3SOW A;  3O33 A; 
#chains in the Genus database with same CATH topology
 2LGV A;  3MHH A;  3L1Z B;  1FP0 A;  2LN0 A;  2K4D A;  4O62 A;  4Z0O A;  1WES A;  2OWA A;  2M3H A;  2E61 A;  2KWO A;  3ZPV 1;  2F6N A;  2JMJ A;  3FL2 A;  1FLL A;  2XB1 A;  3LQI A;  2G43 A;  3MQR A;  1T1H A;  1BOR A;  5SVY A;  3N9P A;  2XOY A;  3GV4 A;  4QF2 A;  2FUU A;  2CKL B;  4UP5 A;  5TAB A;  2CKL A;  1DCQ A;  4GB0 A;  5FEY A;  2CON A;  3RPG B;  3KV5 A;  1MBM A;  3E2D A;  4AP4 A;  2KU3 A;  1WEV A;  4V3L C;  2MNY A;  5G04 B;  4A4C A;  2BAY A;  4AUQ B;  1CZZ A;  2JM3 A;  5SVI A;  4NN2 A;  3O35 A;  3N9N A;  2EOD A;  5H1V A;  1Z2Q A;  3SUB A;  2D8U A;  4YAB A;  4B7Y C;  5B8D A;  3QZV A;  2DX8 A;  2LV9 A;  2UZG A;  4WA6 A;  1V87 A;  1WEM A;  3DPL R;  4W4U A;  4GJH A;  4KG9 A;  4LAD B;  3T9K A;  4WZ0 A;  5H1T A;  3L11 A;  3L1X A;  2C2V S;  1WFK A;  1LDK C;  4GNG A;  5B75 A;  1FLK A;  4UP0 A;  3HCT A;  2EA6 A;  1K2F A;  3IVB A;  5K3Q A;  4QF3 A;  4GWM A;  2GKW A;  3VK6 A;  3U5N A;  4YBM A;  2CRW A;  4ZUX U;  2F42 A;  4UI9 B;  3MQS C;  3RTR B;  3V43 A;  2JMD A;  1ZBD B;  3IVQ A;  2YT5 A;  2L0B A;  4XI1 A;  3PHD A;  1KZZ A;  2F1W A;  2FOJ A;  1VYX A;  2CT2 A;  4JJQ A;  2MD8 C;  4CCG X;  5EYA F;  3N9Q A;  3IVV A;  3M7K A;  2MA6 A;  4Z8M A;  1F62 A;  2EGM A;  2E6S A;  3O37 A;  2YHN A;  5D1L B;  2LDR A;  2ECI A;  3PLW A;  3DDT A;  5AIT A;  3U5O A;  4CA1 A;  2E6R A;  4BBQ A;  3ZPV E;  3T7L A;  4N4F A;  2LGG A;  1LDJ B;  4YAT A;  4H9D A;  4S3O C;  4B86 C;  3IHP A;  2D8S A;  2KGI A;  2DSM A;  2F6J A;  2MUM A;  3Q1D A;  4V3K C;  1DVP A;  2JRJ A;  3LRQ A;  3SOU A;  2ECN A;  4AVX A;  2LXH C;  2YSM A;  4F52 B;  4PPE A;  4Z0R A;  4FK5 A;  2KWN A;  4BHW A;  1L0A A;  4A0C D;  2AN6 A;  4YAX A;  1WIM A;  5DIN A;  1U6G B;  1WEQ A;  2JMI A;  1WE9 A;  2YW8 A;  3N9M A;  2YVR A;  2YRE A;  1QSC A;  5KH9 A;  5TRB A;  2VPG A;  5TDW A;  3HTK C;  2MA5 A;  1FBV A;  1WEO A;  1CA4 A;  2F1X A;  2CSV A;  2VP7 A;  4YSI A;  5LKZ A;  1WIL A;  2YYR A;  4X3G A;  1ZMS A;  5SVI B;  2YUC A;  4GND A;  1E4U A;  2NAA A;  2XEU A;  5TDR A;  2CR2 A;  2XOC A;  1VD4 A;  2RSD A;  2QIZ A;  4OGE A;  2KWK A;  3FJU B;  3DQV R;  5SVX A;  4R8P K;  1YY6 A;  2FOO A;  3EB5 A;  3FAO A;  1WEN A;  1WGM A;  2G6Q A;  2P57 A;  2CSY A;  2FSA A;  5KH3 A;  3SHB A;  2VPB A;  4FJC A;  2LGL A;  4GHU A;  3MHS A;  5D1M B;  3HQM A;  2VJF A;  2KGG A;  3ZNI A;  2L43 A;  1RF3 A;  4A4B A;  1MM2 A;  2IQJ A;  1N87 A;  4YBS A;  1WEE A;  2CSZ A;  1JM7 B;  3KDE C;  1LB5 A;  3KNV A;  4YC9 A;  1JM7 A;  2MNZ A;  3ZVY A;  4S3O B;  5LKT A;  2KKX A;  2YUR A;  2KWJ A;  2EXU A;  4YBT A;  3HCU A;  3SOX A;  5AIU A;  1Z6U A;  3C6W A;  3O34 A;  1CZY A;  2LQ6 A;  3HQL A;  2Y1N A;  5I3L A;  3O36 A;  5H1U A;  5LKX A;  1D01 A;  4GWN A;  3ASL A;  2EGP A;  2C2L A;  2L5U A;  2M13 A;  3LJU X;  2Y43 A;  1IYM A;  4GNF A;  3N9L A;  2KIZ A;  2HDP A;  2F1Y A;  4P5O B;  3N9O A;  3HQH A;  5B78 A;  3O70 A;  2M1R A;  4FO9 A;  4R2Y A;  2JUN A;  4L58 A;  2MIQ A;  4A49 A;  1D0A A;  2QIC A;  2YQM A;  3GL6 A;  2LXP C;  2K17 A;  2MKE A;  3HCS A;  1HYJ A;  1X4J A;  4YAD A;  4N3W A;  2H0D B;  4GNE A;  2ECJ A;  2KRE A;  2MD7 B;  4I7C A;  4I7B A;  2H0D A;  3M99 A;  5KH7 A;  3C5K A;  2FOP A;  2K1J A;  2B0O E;  3ZYQ A;  2XOZ A;  4M4E A;  3KV6 A;  3LQJ A;  2ECT A;  3M62 A;  1D0J A;  2LAU A;  4ZQL A;  3JUE A;  4F1P A;  1Z60 A;  5B76 A;  1CHC A;  3O7A A;  4O1V A;  5H9M A;  3HU6 A;  1VFY A;  2G45 A;  4OGC A;  5FB1 A;  2XXN A;  2M6M A;  2MT5 A;  2ECV A;  2OXQ C;  2A25 A;  2ECG A;  3LVQ E;  2RI7 A;  1F3V B;  3ZJB A;  2YHO A;  4LJN A;  2VNF A;  2L75 A;  2FFW A;  3EB6 A;  5E1T A;  1HYI A;  2VJF B;  1XWH A;  4C9Z A;  4ZDT A;  5FB0 A;  2KE1 A;  2PUY A;  1YZE A;  2I50 A;  2DJA A;  2QJ0 A;  2Y1M A;  4L7X A;  3LQH A;  5LCW B;  5TBN A;  1X4I A;  5LKU A;  5B79 A;  3U5M A;  3HQI A;  5DKA A;  2KR4 A;  2ECW A;  2VJE B;  1LB6 A;  4MSX A;  3H7H A;  3T6R A;  2XP0 A;  5G05 B;  2VJE A;  5D1K B;  4FIP A;  2KFT A;  4IC3 A;  5B77 A;  3U5P A;  4PTB A;  1CA9 A;  3FEH A;  1G25 A;  1WEU A;  3FM8 C;  3ZVZ B;  4AYC B;  2LGK A;  3NG2 A;  2KKY A;  2YU4 A;  4I7D A;  4R7E A;  5G0F A;  3RPG C;  4AYC A;  4WZ2 A;  5FER A;  2YQL A;  2IDA A;  2HYE D;  4MVT A;  2FUI A;  2RR4 A;  3PUR A;  4LK9 A;  1JOC A;  4O64 A;  4TKP B;  3LDY A;  2L80 A;  2KYU A;  4IC2 A;  2CRR A;  4Q6F A;  5J3X A;  2L7P A;  2FD4 A;  3I2D A;  3LVR E;  2YSJ A;  3O47 A;  3HSV A;  1LB4 A;  2K16 A;  1X4U A;  3KQI A;  3MDB C;  4LKA A;  2VPE A;  2PNX A;  3PUQ A;  4LLB A;  1WEW A;  2LRI C;  2VPD A;  5C11 A;  5C13 A;  5JG6 A;  2F1Z A;  1WEP A;  3M63 A;  4QQ4 A;  4WZ3 B;  1D00 A;  1MM3 A;  2ZET C;  3FAN A;  3ZTG A;  4K8U A;  2M85 A;  1RMD A;  3SOW A;  3DWD A;  3O33 A; 
#chains in the Genus database with same CATH homology
 2LGV A;  3MHH A;  3L1Z B;  1FP0 A;  2LN0 A;  2K4D A;  1WES A;  2M3H A;  2KWO A;  3ZPV 1;  2F6N A;  2JMJ A;  3FL2 A;  1FLL A;  2XB1 A;  3LQI A;  2G43 A;  3MQR A;  1T1H A;  1BOR A;  3N9P A;  3GV4 A;  4QF2 A;  2FUU A;  2CKL B;  4UP5 A;  5TAB A;  2CKL A;  4GB0 A;  5FEY A;  3RPG B;  3KV5 A;  4AP4 A;  2KU3 A;  1WEV A;  4V3L C;  2MNY A;  5G04 B;  4A4C A;  2BAY A;  4AUQ B;  1CZZ A;  4NN2 A;  3O35 A;  3N9N A;  2EOD A;  5H1V A;  1Z2Q A;  4YAB A;  4B7Y C;  5B8D A;  3QZV A;  2DX8 A;  2LV9 A;  2UZG A;  4WA6 A;  1V87 A;  1WEM A;  3DPL R;  4W4U A;  4GJH A;  4KG9 A;  4LAD B;  4WZ0 A;  5H1T A;  3L11 A;  3L1X A;  2C2V S;  1WFK A;  1LDK C;  4GNG A;  5B75 A;  1FLK A;  4UP0 A;  3HCT A;  2EA6 A;  1K2F A;  3IVB A;  4QF3 A;  4GWM A;  2GKW A;  3VK6 A;  3U5N A;  4YBM A;  4ZUX U;  2F42 A;  4UI9 B;  3MQS C;  3RTR B;  3V43 A;  2JMD A;  1ZBD B;  3IVQ A;  2YT5 A;  2L0B A;  4XI1 A;  3PHD A;  1KZZ A;  2F1W A;  2FOJ A;  1VYX A;  2CT2 A;  4JJQ A;  2MD8 C;  4CCG X;  5EYA F;  3N9Q A;  3IVV A;  2MA6 A;  4Z8M A;  1F62 A;  2E6S A;  3O37 A;  2YHN A;  5D1L B;  2LDR A;  2ECI A;  5AIT A;  3U5O A;  4CA1 A;  2E6R A;  4BBQ A;  3ZPV E;  3T7L A;  4N4F A;  2LGG A;  1LDJ B;  4YAT A;  4S3O C;  4B86 C;  3IHP A;  2D8S A;  2KGI A;  2F6J A;  2MUM A;  4V3K C;  1DVP A;  2JRJ A;  3LRQ A;  3SOU A;  2ECN A;  4AVX A;  2LXH C;  2YSM A;  4F52 B;  4PPE A;  4FK5 A;  2KWN A;  4BHW A;  1L0A A;  4A0C D;  2AN6 A;  4YAX A;  1WIM A;  5DIN A;  1U6G B;  1WEQ A;  2JMI A;  1WE9 A;  2YW8 A;  3N9M A;  2YRE A;  1QSC A;  5KH9 A;  5TRB A;  2VPG A;  5TDW A;  3HTK C;  2MA5 A;  1FBV A;  1WEO A;  1CA4 A;  2F1X A;  2VP7 A;  4YSI A;  5LKZ A;  1WIL A;  2YYR A;  4X3G A;  1ZMS A;  2YUC A;  4GND A;  1E4U A;  2NAA A;  2XEU A;  5TDR A;  2CR2 A;  1VD4 A;  2RSD A;  2QIZ A;  2KWK A;  3DQV R;  4R8P K;  1YY6 A;  2FOO A;  3EB5 A;  1WEN A;  1WGM A;  2G6Q A;  2CSY A;  2FSA A;  5KH3 A;  3SHB A;  2VPB A;  4FJC A;  2LGL A;  4GHU A;  3MHS A;  5D1M B;  3HQM A;  2VJF A;  2KGG A;  3ZNI A;  2L43 A;  1RF3 A;  4A4B A;  1MM2 A;  1N87 A;  4YBS A;  1WEE A;  2CSZ A;  1JM7 B;  1LB5 A;  3KNV A;  4YC9 A;  1JM7 A;  2MNZ A;  3ZVY A;  4S3O B;  5LKT A;  2YUR A;  2KWJ A;  4YBT A;  3HCU A;  3SOX A;  5AIU A;  1Z6U A;  3C6W A;  3O34 A;  1CZY A;  2LQ6 A;  3HQL A;  2Y1N A;  5I3L A;  3O36 A;  5H1U A;  5LKX A;  1D01 A;  4GWN A;  3ASL A;  2EGP A;  2C2L A;  2L5U A;  2Y43 A;  1IYM A;  4GNF A;  3N9L A;  2KIZ A;  2HDP A;  2F1Y A;  4P5O B;  3N9O A;  3HQH A;  5B78 A;  3O70 A;  2M1R A;  4FO9 A;  4R2Y A;  4A49 A;  4L58 A;  2MIQ A;  1D0A A;  2QIC A;  2YQM A;  3GL6 A;  2LXP C;  2K17 A;  3HCS A;  1HYJ A;  1X4J A;  4YAD A;  4N3W A;  2H0D B;  4GNE A;  2ECJ A;  2KRE A;  2MD7 B;  4I7C A;  4I7B A;  2H0D A;  3M99 A;  5KH7 A;  3C5K A;  2FOP A;  2K1J A;  3ZYQ A;  4M4E A;  3KV6 A;  3LQJ A;  2ECT A;  3M62 A;  1D0J A;  4ZQL A;  1Z60 A;  5B76 A;  1CHC A;  3O7A A;  4O1V A;  5H9M A;  3HU6 A;  1VFY A;  2G45 A;  5FB1 A;  2XXN A;  2M6M A;  2MT5 A;  2ECV A;  2OXQ C;  2A25 A;  2ECG A;  2RI7 A;  1F3V B;  3ZJB A;  2YHO A;  4LJN A;  2VNF A;  2L75 A;  3EB6 A;  5E1T A;  1HYI A;  2VJF B;  1XWH A;  4C9Z A;  4ZDT A;  5FB0 A;  2KE1 A;  2PUY A;  1YZE A;  2I50 A;  2QJ0 A;  2Y1M A;  4L7X A;  3LQH A;  5LCW B;  5TBN A;  1X4I A;  5LKU A;  5B79 A;  3U5M A;  3HQI A;  5DKA A;  2KR4 A;  2ECW A;  2VJE B;  1LB6 A;  4MSX A;  3T6R A;  5G05 B;  2VJE A;  5D1K B;  4FIP A;  2KFT A;  4IC3 A;  5B77 A;  3U5P A;  4PTB A;  1CA9 A;  1G25 A;  1WEU A;  3ZVZ B;  4AYC B;  2LGK A;  3NG2 A;  2YU4 A;  4I7D A;  4R7E A;  5G0F A;  3RPG C;  4AYC A;  4WZ2 A;  5FER A;  2YQL A;  2IDA A;  2HYE D;  4MVT A;  2FUI A;  3PUR A;  4LK9 A;  1JOC A;  4O64 A;  4TKP B;  2L80 A;  2KYU A;  4IC2 A;  4Q6F A;  5J3X A;  3I2D A;  2YSJ A;  3HSV A;  1LB4 A;  2K16 A;  1X4U A;  3KQI A;  4LKA A;  2VPE A;  2PNX A;  3PUQ A;  4LLB A;  1WEW A;  2LRI C;  2VPD A;  5C11 A;  5C13 A;  5JG6 A;  2F1Z A;  1WEP A;  3M63 A;  4WZ3 B;  1D00 A;  1MM3 A;  2ZET C;  3ZTG A;  4K8U A;  2M85 A;  1RMD A;  3SOW A;  3O33 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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