1CZZA

Structure of tnf receptor associated factor 2 in complex with a 17-residue cd40 peptide
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
187
structure length
187
Chain Sequence
EALSSKVQQLERSIGLKDLAMADLEQKVLEMEASTYDGVFIWKISDFPRKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQNNREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDLTGL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The structural basis for the recognition of diverse receptor sequences by TRAF2.
pubmed doi rcsb
molecule tags Apoptosis
source organism Homo sapiens
molecule keywords TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED PROTEIN 2
total genus 46
structure length 187
sequence length 187
chains with identical sequence B, C
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 1999-09-07
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.210.10 Mainly Beta Sandwich Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A 1czzA00
1KZZA 3MQRA 3ZJBA 1CA4A 5E1TA 3HQMA 1LB5A 1F3VB 4GJHA 4I7BA 2CR2A 4GHUA 4Z8MA 4X3GA 4CA1A 2F1ZA 2FOOA 1FLKA 1CA9A 4I7DA 1D00A 3HQIA 3MQSC 4GWMA 4I7CA 1D01A 1QSCA 1ZMSA 4KG9A 4YSIA 2XXNA 3HQHA 5H9MA 1LB6A 4K8UA 2GKWA 3IVBA 1CZZA 2A25A 2AN6A 4O1VA 1K2FA 1YY6A 3HSVA 2F1XA 2F1YA 3HQLA 3IVVA 1FLLA 1D0JA 1D0AA 2FOPA 1L0AA 2FOJA 4JJQA 4GWNA 4M4EA 4C9ZA 1YZEA 1RF3A 3HU6A 3IVQA 1CZYA 1LB4A 2F1WA
chains in the Genus database with same CATH superfamily
1KZZA 3MQRA 3ZJBA 1CA4A 5E1TA 3HQMA 1LB5A 1F3VB 4GJHA 4I7BA 2CR2A 4GHUA 4Z8MA 4X3GA 4CA1A 2F1ZA 2FOOA 1FLKA 1CA9A 4I7DA 1D00A 3HQIA 3MQSC 4GWMA 4I7CA 1D01A 1QSCA 1ZMSA 4KG9A 4YSIA 2XXNA 3HQHA 5H9MA 1LB6A 4K8UA 2GKWA 3IVBA 1CZZA 2A25A 2AN6A 4O1VA 1K2FA 1YY6A 3HSVA 2F1XA 2F1YA 3HQLA 3IVVA 1FLLA 1D0JA 1D0AA 2FOPA 1L0AA 2FOJA 4JJQA 4GWNA 4M4EA 4C9ZA 1YZEA 1RF3A 3HU6A 3IVQA 1CZYA 1LB4A 2F1WA
chains in the Genus database with same CATH topology
1KZZA 3MQRA 3ZJBA 1CA4A 5E1TA 3HQMA 1LB5A 1F3VB 4GJHA 4I7BA 2CR2A 4GHUA 4Z8MA 4X3GA 4CA1A 2F1ZA 2FOOA 1FLKA 1CA9A 4I7DA 1D00A 3HQIA 3MQSC 4GWMA 4I7CA 1D01A 1QSCA 1ZMSA 4KG9A 4YSIA 2XXNA 3HQHA 5H9MA 1LB6A 4K8UA 2GKWA 3IVBA 1CZZA 2A25A 2AN6A 4O1VA 1K2FA 1YY6A 3HSVA 2F1XA 2F1YA 3HQLA 3IVVA 1FLLA 1D0JA 1D0AA 2FOPA 1L0AA 2FOJA 4JJQA 4GWNA 4M4EA 4C9ZA 1YZEA 1RF3A 3HU6A 3IVQA 1CZYA 1LB4A 2F1WA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KZZ A;  3MQR A;  3ZJB A;  1CA4 A;  5E1T A;  3HQM A;  1LB5 A;  1F3V B;  4GJH A;  4I7B A;  2CR2 A;  4GHU A;  4Z8M A;  4X3G A;  4CA1 A;  2F1Z A;  2FOO A;  1FLK A;  1CA9 A;  4I7D A;  1D00 A;  3HQI A;  3MQS C;  4GWM A;  4I7C A;  1D01 A;  1QSC A;  1ZMS A;  4KG9 A;  4YSI A;  2XXN A;  3HQH A;  5H9M A;  1LB6 A;  4K8U A;  2GKW A;  3IVB A;  1CZZ A;  2A25 A;  2AN6 A;  4O1V A;  1K2F A;  1YY6 A;  3HSV A;  2F1X A;  2F1Y A;  3HQL A;  3IVV A;  1FLL A;  1D0J A;  1D0A A;  2FOP A;  1L0A A;  2FOJ A;  4JJQ A;  4GWN A;  4M4E A;  4C9Z A;  1YZE A;  1RF3 A;  3HU6 A;  3IVQ A;  1CZY A;  1LB4 A;  2F1W A; 
#chains in the Genus database with same CATH topology
 1KZZ A;  3MQR A;  3ZJB A;  1CA4 A;  5E1T A;  3HQM A;  1LB5 A;  1F3V B;  4GJH A;  4I7B A;  2CR2 A;  4GHU A;  4Z8M A;  4X3G A;  4CA1 A;  2F1Z A;  2FOO A;  1FLK A;  1CA9 A;  4I7D A;  1D00 A;  3HQI A;  3MQS C;  4GWM A;  4I7C A;  1D01 A;  1QSC A;  1ZMS A;  4KG9 A;  4YSI A;  2XXN A;  3HQH A;  5H9M A;  1LB6 A;  4K8U A;  2GKW A;  3IVB A;  1CZZ A;  2A25 A;  2AN6 A;  4O1V A;  1K2F A;  1YY6 A;  3HSV A;  2F1X A;  2F1Y A;  3HQL A;  3IVV A;  1FLL A;  1D0J A;  1D0A A;  2FOP A;  1L0A A;  2FOJ A;  4JJQ A;  4GWN A;  4M4E A;  4C9Z A;  1YZE A;  1RF3 A;  3HU6 A;  3IVQ A;  1CZY A;  1LB4 A;  2F1W A; 
#chains in the Genus database with same CATH homology
 1KZZ A;  3MQR A;  3ZJB A;  1CA4 A;  5E1T A;  3HQM A;  1LB5 A;  1F3V B;  4GJH A;  4I7B A;  2CR2 A;  4GHU A;  4Z8M A;  4X3G A;  4CA1 A;  2F1Z A;  2FOO A;  1FLK A;  1CA9 A;  4I7D A;  1D00 A;  3HQI A;  3MQS C;  4GWM A;  4I7C A;  1D01 A;  1QSC A;  1ZMS A;  4KG9 A;  4YSI A;  2XXN A;  3HQH A;  5H9M A;  1LB6 A;  4K8U A;  2GKW A;  3IVB A;  1CZZ A;  2A25 A;  2AN6 A;  4O1V A;  1K2F A;  1YY6 A;  3HSV A;  2F1X A;  2F1Y A;  3HQL A;  3IVV A;  1FLL A;  1D0J A;  1D0A A;  2FOP A;  1L0A A;  2FOJ A;  4JJQ A;  4GWN A;  4M4E A;  4C9Z A;  1YZE A;  1RF3 A;  3HU6 A;  3IVQ A;  1CZY A;  1LB4 A;  2F1W A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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