1DPZ | Genus

Total Genus 111

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	111
sequence length	345
structure length	345
Chain Sequence	MKVAVLPGDGIGPEVTEAALKVLRALDEAEGLGLAYEVFPFGGAAIDAFGEPFPEPTRKGVEEAEAVLLGSVGGPKWDGLPRKIRPETGLLSLRKSQDLFANLRPAKVFPGLERLSPLKEEIARGVDVLIVRELTGGIYFGEPRGMSEAEAWNTERYSKPEVERVARVAFELARKRRKHVVSVDKANVLEVGEFWRKTVEEVGRGYPDVALEHQYVDAMAMHLVRSPARFDVVVTGNIFGDILSDLASVLPGSLGLLPSASLGRGTPVFEPVHGSAPDIAGKGIANPTAAILSAAMMLEHAFGLVELARKVEDAVAKALLETPPPDLGGSAGTEAFTATVEAFTA

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Crystal structures of 3-isopropylmalate dehydrogenases with mutations at the C-terminus: crystallographic analyses of structure-stability relationships. pubmed doi rcsb
molecule keywords	3-ISOPROPYLMALATE DEHYDROGENASE
molecule tags	Oxidoreductase
source organism	Thermus thermophilus
total genus	111
structure length	345
sequence length	345
chains with identical sequence	B
ec nomenclature	ec 1.1.1.85: 3-isopropylmalate dehydrogenase.
pdb deposition date	1999-12-29

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.40.718.10	Alpha Beta	3-Layer(aba) Sandwich	Isopropylmalate Dehydrogenase	Isopropylmalate Dehydrogenase	1dpzA00

8ICDA 1CW1A 5J32A 1HJ6A 2Y42A 1U7NA 5DE1A 1WPWA 3VMKA 5HN5A 4AJRA 2D4VA 1DR8A 1T0LA 4UMYA 3AH3A 1OSIA 1CNZA 1XAAA 4L06A 5ICDA 4AJSA 3UF6A 5K11A 1GC9A 1R8KA 3WZVA 5J34A 5GRFB 1PS6A 2QFWA 5HN3A 5L58A 3R8WA 3TSNA 2IV0A 5GRFA 2Y41A 4I3KA 2D1CA 4ATYA 1IDFA 1CM7A 3MASB 1BL5A 3TY3A 5GREB 1CW4A 1PS7A 2Y40A 3MARA 3UDUA 3VL4A 2E5MA 4XRXA 1IPDA 3MASA 4AJAA 5GREA 5HN4A 3VL3A 3LXYA 4BNPA 1IKAA 1OSJA 6ICDA 1LWDA 1DPZA 1CW7A 2QFYA 2ZTWA 5GRIB 3DMSA 1VLCA 4L04A 4WUOA 3WZYA 1AI3A 5LGEA 5HN6A 4AJ3A 1G2UA 3UDOA 2QFXA 5GRLB 5GRIA 3LCBC 3MAPA 3U9EA 1SJSA 3BLVB 3VL7A 5J33A 1TYOA 3TNGA 4AJBA 3FMXX 1HEXA 3VKZA 3INMA 3BLXA 4AOVA 1XABA 1ZORA 1V53A 4F7IA 1GROA 4XXVA 1AI2A 5GRLA 1GRPA 1PB1A 2HI1A 3US8A 4AOUA 3BLVA 2UXQA 4AJCA 2UXRA 1IDDA 4UMXA 1XADA 3ASJA 5I96A 2QFVA 1XKDA 1X0LA 4JA8A 2E0CA 4ICDA 3VMLA 5I95A 1IDCA 3VL2A 1XGVA 3WZWA 4IWHA 1IDMA 1P8FA 1PB3A 1V94A 3U1HA 2Y3ZA 3BLXB 4I3LA 5GRHA 1GC8A 7ICDA 4HCXA 9ICDA 5L57A 1HQSA 1V5BA 1IDEA 4YB4A 1A05A 2AYQA 3VL6A 3WZXA 3TY4A 3ICDA 1VI1A 1ISOA 1W0DA 2G4OA 1DR0A 2DHTA 3FLKA 1YCOA 5K10A 4JQPA 1YXOA 5GRHB 1WALA 1T09A 4AOYA 4L03A 3VMJA 4XS3A 4P69C 4Y1PA 4KZOA 1XACA 1PTMA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 8ICD A;  1CW1 A;  5J32 A;  1HJ6 A;  2Y42 A;  1U7N A;  5DE1 A;  1WPW A;  3VMK A;  5HN5 A;  4AJR A;  2D4V A;  1DR8 A;  1T0L A;  4UMY A;  3AH3 A;  1OSI A;  1CNZ A;  1XAA A;  4L06 A;  5ICD A;  4AJS A;  3UF6 A;  5K11 A;  1GC9 A;  1R8K A;  3WZV A;  5J34 A;  5GRF B;  1PS6 A;  2QFW A;  5HN3 A;  5L58 A;  3R8W A;  3TSN A;  2IV0 A;  5GRF A;  2Y41 A;  4I3K A;  2D1C A;  4ATY A;  1IDF A;  1CM7 A;  3MAS B;  1BL5 A;  3TY3 A;  5GRE B;  1CW4 A;  1PS7 A;  2Y40 A;  3MAR A;  3UDU A;  3VL4 A;  2E5M A;  4XRX A;  1IPD A;  3MAS A;  4AJA A;  5GRE A;  5HN4 A;  3VL3 A;  3LXY A;  4BNP A;  1IKA A;  1OSJ A;  6ICD A;  1LWD A;  1DPZ A;  1CW7 A;  2QFY A;  2ZTW A;  5GRI B;  3DMS A;  1VLC A;  4L04 A;  4WUO A;  3WZY A;  1AI3 A;  5LGE A;  5HN6 A;  4AJ3 A;  1G2U A;  3UDO A;  2QFX A;  5GRL B;  5GRI A;  3LCB C;  3MAP A;  3U9E A;  1SJS A;  3BLV B;  3VL7 A;  5J33 A;  1TYO A;  3TNG A;  4AJB A;  3FMX X;  1HEX A;  3VKZ A;  3INM A;  3BLX A;  4AOV A;  1XAB A;  1ZOR A;  1V53 A;  4F7I A;  1GRO A;  4XXV A;  1AI2 A;  5GRL A;  1GRP A;  1PB1 A;  2HI1 A;  3US8 A;  4AOU A;  3BLV A;  2UXQ A;  4AJC A;  2UXR A;  1IDD A;  4UMX A;  1XAD A;  3ASJ A;  5I96 A;  2QFV A;  1XKD A;  1X0L A;  4JA8 A;  2E0C A;  4ICD A;  3VML A;  5I95 A;  1IDC A;  3VL2 A;  1XGV A;  3WZW A;  4IWH A;  1IDM A;  1P8F A;  1PB3 A;  1V94 A;  3U1H A;  2Y3Z A;  3BLX B;  4I3L A;  5GRH A;  1GC8 A;  7ICD A;  4HCX A;  9ICD A;  5L57 A;  1HQS A;  1V5B A;  1IDE A;  4YB4 A;  1A05 A;  2AYQ A;  3VL6 A;  3WZX A;  3TY4 A;  3ICD A;  1VI1 A;  1ISO A;  1W0D A;  2G4O A;  1DR0 A;  2DHT A;  3FLK A;  1YCO A;  5K10 A;  4JQP A;  1YXO A;  5GRH B;  1WAL A;  1T09 A;  4AOY A;  4L03 A;  3VMJ A;  4XS3 A;  4P69 C;  4Y1P A;  4KZO A;  1XAC A;  1PTM A; 
#chains in the Genus database with same CATH topology
 8ICD A;  1CW1 A;  5J32 A;  1HJ6 A;  2Y42 A;  1U7N A;  5DE1 A;  1WPW A;  3VMK A;  5HN5 A;  4AJR A;  2D4V A;  1DR8 A;  1T0L A;  4UMY A;  3AH3 A;  1OSI A;  1CNZ A;  1XAA A;  4L06 A;  5ICD A;  4AJS A;  3UF6 A;  5K11 A;  1GC9 A;  1R8K A;  3WZV A;  5J34 A;  5GRF B;  1PS6 A;  2QFW A;  5HN3 A;  5L58 A;  3R8W A;  3TSN A;  2IV0 A;  5GRF A;  2Y41 A;  4I3K A;  2D1C A;  4ATY A;  1IDF A;  1CM7 A;  3MAS B;  1BL5 A;  3TY3 A;  5GRE B;  1CW4 A;  1PS7 A;  2Y40 A;  3MAR A;  3UDU A;  3VL4 A;  2E5M A;  4XRX A;  1IPD A;  3MAS A;  4AJA A;  5GRE A;  5HN4 A;  3VL3 A;  3LXY A;  4BNP A;  1IKA A;  1OSJ A;  6ICD A;  1LWD A;  1DPZ A;  1CW7 A;  2QFY A;  2ZTW A;  5GRI B;  3DMS A;  1VLC A;  4L04 A;  4WUO A;  3WZY A;  1AI3 A;  5LGE A;  5HN6 A;  4AJ3 A;  1G2U A;  3UDO A;  2QFX A;  5GRL B;  5GRI A;  3LCB C;  3MAP A;  3U9E A;  1SJS A;  3BLV B;  3VL7 A;  5J33 A;  1TYO A;  3TNG A;  4AJB A;  3FMX X;  1HEX A;  3VKZ A;  3INM A;  3BLX A;  4AOV A;  1XAB A;  1ZOR A;  1V53 A;  4F7I A;  1GRO A;  4XXV A;  1AI2 A;  5GRL A;  1GRP A;  1PB1 A;  2HI1 A;  3US8 A;  4AOU A;  3BLV A;  2UXQ A;  4AJC A;  2UXR A;  1IDD A;  4UMX A;  1XAD A;  3ASJ A;  5I96 A;  2QFV A;  1XKD A;  1X0L A;  4JA8 A;  2E0C A;  4ICD A;  3VML A;  5I95 A;  1IDC A;  3VL2 A;  1XGV A;  3WZW A;  4IWH A;  1IDM A;  1P8F A;  1PB3 A;  1V94 A;  3U1H A;  2Y3Z A;  3BLX B;  4I3L A;  5GRH A;  1GC8 A;  7ICD A;  4HCX A;  9ICD A;  5L57 A;  1HQS A;  1V5B A;  1IDE A;  4YB4 A;  1A05 A;  2AYQ A;  3VL6 A;  3WZX A;  3TY4 A;  3ICD A;  1VI1 A;  1ISO A;  1W0D A;  2G4O A;  1DR0 A;  2DHT A;  3FLK A;  1YCO A;  5K10 A;  4JQP A;  1YXO A;  5GRH B;  1WAL A;  1T09 A;  4AOY A;  4L03 A;  3VMJ A;  4XS3 A;  4P69 C;  4Y1P A;  4KZO A;  1XAC A;  1PTM A; 
#chains in the Genus database with same CATH homology
 8ICD A;  1CW1 A;  5J32 A;  1HJ6 A;  2Y42 A;  1U7N A;  5DE1 A;  1WPW A;  3VMK A;  5HN5 A;  4AJR A;  2D4V A;  1DR8 A;  1T0L A;  4UMY A;  3AH3 A;  1OSI A;  1CNZ A;  1XAA A;  4L06 A;  5ICD A;  4AJS A;  3UF6 A;  5K11 A;  1GC9 A;  1R8K A;  3WZV A;  5J34 A;  5GRF B;  1PS6 A;  2QFW A;  5HN3 A;  5L58 A;  3R8W A;  3TSN A;  2IV0 A;  5GRF A;  2Y41 A;  4I3K A;  2D1C A;  4ATY A;  1IDF A;  1CM7 A;  3MAS B;  1BL5 A;  3TY3 A;  5GRE B;  1CW4 A;  1PS7 A;  2Y40 A;  3MAR A;  3UDU A;  3VL4 A;  2E5M A;  4XRX A;  1IPD A;  3MAS A;  4AJA A;  5GRE A;  5HN4 A;  3VL3 A;  3LXY A;  4BNP A;  1IKA A;  1OSJ A;  6ICD A;  1LWD A;  1DPZ A;  1CW7 A;  2QFY A;  2ZTW A;  5GRI B;  3DMS A;  1VLC A;  4L04 A;  4WUO A;  3WZY A;  1AI3 A;  5LGE A;  5HN6 A;  4AJ3 A;  1G2U A;  3UDO A;  2QFX A;  5GRL B;  5GRI A;  3LCB C;  3MAP A;  3U9E A;  1SJS A;  3BLV B;  3VL7 A;  5J33 A;  1TYO A;  3TNG A;  4AJB A;  3FMX X;  1HEX A;  3VKZ A;  3INM A;  3BLX A;  4AOV A;  1XAB A;  1ZOR A;  1V53 A;  4F7I A;  1GRO A;  4XXV A;  1AI2 A;  5GRL A;  1GRP A;  1PB1 A;  2HI1 A;  3US8 A;  4AOU A;  3BLV A;  2UXQ A;  4AJC A;  2UXR A;  1IDD A;  4UMX A;  1XAD A;  3ASJ A;  5I96 A;  2QFV A;  1XKD A;  1X0L A;  4JA8 A;  2E0C A;  4ICD A;  3VML A;  5I95 A;  1IDC A;  3VL2 A;  1XGV A;  3WZW A;  4IWH A;  1IDM A;  1P8F A;  1PB3 A;  1V94 A;  3U1H A;  2Y3Z A;  3BLX B;  4I3L A;  5GRH A;  1GC8 A;  7ICD A;  4HCX A;  9ICD A;  5L57 A;  1HQS A;  1V5B A;  1IDE A;  4YB4 A;  1A05 A;  2AYQ A;  3VL6 A;  3WZX A;  3TY4 A;  3ICD A;  1VI1 A;  1ISO A;  1W0D A;  2G4O A;  1DR0 A;  2DHT A;  3FLK A;  1YCO A;  5K10 A;  4JQP A;  1YXO A;  5GRH B;  1WAL A;  1T09 A;  4AOY A;  4L03 A;  3VMJ A;  4XS3 A;  4P69 C;  4Y1P A;  4KZO A;  1XAC A;  1PTM A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

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1DPZA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN