1F3VB

Crystal structure of the complex between the n-terminal domain of tradd and the traf domain of traf2
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
171
structure length
171
Chain Sequence
KDLAMADLEQKVLEMEASTYDGVFIWKISDFPRKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQNNREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDLTGL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title A novel mechanism of TRAF signaling revealed by structural and functional analyses of the TRADD-TRAF2 interaction.
pubmed doi rcsb
molecule tags Apoptosis
source organism Homo sapiens
molecule keywords TUMOR NECROSIS FACTOR RECEPTOR TYPE 1 ASSOCIATED DEATH DOMAI
total genus 35
structure length 171
sequence length 171
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2000-06-06
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.210.10 Mainly Beta Sandwich Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A 1f3vB00
1KZZA 1FLKA 4CA1A 1CZYA 1D0AA 3HQMA 4YSIA 3MQRA 4I7BA 2XXNA 1L0AA 3IVBA 5H9MA 2A25A 4GHUA 2FOOA 4I7DA 2AN6A 1CA9A 2F1ZA 2F1XA 4I7CA 1FLLA 1D0JA 1F3VB 1LB4A 1CA4A 1YZEA 2FOJA 3IVVA 3HQHA 3MQSC 4X3GA 2FOPA 3ZJBA 1LB5A 1QSCA 5E1TA 4GWNA 4GWMA 1RF3A 1YY6A 1D01A 3HQIA 2F1WA 4M4EA 1CZZA 1K2FA 1ZMSA 2GKWA 3HQLA 4GJHA 4C9ZA 4KG9A 1D00A 4K8UA 4JJQA 3IVQA 2CR2A 4O1VA 4Z8MA 3HU6A 3HSVA 1LB6A 2F1YA
chains in the Genus database with same CATH superfamily
1KZZA 1FLKA 4CA1A 1CZYA 1D0AA 3HQMA 4YSIA 3MQRA 4I7BA 2XXNA 1L0AA 3IVBA 5H9MA 2A25A 4GHUA 2FOOA 4I7DA 2AN6A 1CA9A 2F1ZA 2F1XA 4I7CA 1FLLA 1D0JA 1F3VB 1LB4A 1CA4A 1YZEA 2FOJA 3IVVA 3HQHA 3MQSC 4X3GA 2FOPA 3ZJBA 1LB5A 1QSCA 5E1TA 4GWNA 4GWMA 1RF3A 1YY6A 1D01A 3HQIA 2F1WA 4M4EA 1CZZA 1K2FA 1ZMSA 2GKWA 3HQLA 4GJHA 4C9ZA 4KG9A 1D00A 4K8UA 4JJQA 3IVQA 2CR2A 4O1VA 4Z8MA 3HU6A 3HSVA 1LB6A 2F1YA
chains in the Genus database with same CATH topology
1KZZA 1FLKA 4CA1A 1CZYA 1D0AA 3HQMA 4YSIA 3MQRA 4I7BA 2XXNA 1L0AA 3IVBA 5H9MA 2A25A 4GHUA 2FOOA 4I7DA 2AN6A 1CA9A 2F1ZA 2F1XA 4I7CA 1FLLA 1D0JA 1F3VB 1LB4A 1CA4A 1YZEA 2FOJA 3IVVA 3HQHA 3MQSC 4X3GA 2FOPA 3ZJBA 1LB5A 1QSCA 5E1TA 4GWNA 4GWMA 1RF3A 1YY6A 1D01A 3HQIA 2F1WA 4M4EA 1CZZA 1K2FA 1ZMSA 2GKWA 3HQLA 4GJHA 4C9ZA 4KG9A 1D00A 4K8UA 4JJQA 3IVQA 2CR2A 4O1VA 4Z8MA 3HU6A 3HSVA 1LB6A 2F1YA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KZZ A;  1FLK A;  4CA1 A;  1CZY A;  1D0A A;  3HQM A;  4YSI A;  3MQR A;  4I7B A;  2XXN A;  1L0A A;  3IVB A;  5H9M A;  2A25 A;  4GHU A;  2FOO A;  4I7D A;  2AN6 A;  1CA9 A;  2F1Z A;  2F1X A;  4I7C A;  1FLL A;  1D0J A;  1F3V B;  1LB4 A;  1CA4 A;  1YZE A;  2FOJ A;  3IVV A;  3HQH A;  3MQS C;  4X3G A;  2FOP A;  3ZJB A;  1LB5 A;  1QSC A;  5E1T A;  4GWN A;  4GWM A;  1RF3 A;  1YY6 A;  1D01 A;  3HQI A;  2F1W A;  4M4E A;  1CZZ A;  1K2F A;  1ZMS A;  2GKW A;  3HQL A;  4GJH A;  4C9Z A;  4KG9 A;  1D00 A;  4K8U A;  4JJQ A;  3IVQ A;  2CR2 A;  4O1V A;  4Z8M A;  3HU6 A;  3HSV A;  1LB6 A;  2F1Y A; 
#chains in the Genus database with same CATH topology
 1KZZ A;  1FLK A;  4CA1 A;  1CZY A;  1D0A A;  3HQM A;  4YSI A;  3MQR A;  4I7B A;  2XXN A;  1L0A A;  3IVB A;  5H9M A;  2A25 A;  4GHU A;  2FOO A;  4I7D A;  2AN6 A;  1CA9 A;  2F1Z A;  2F1X A;  4I7C A;  1FLL A;  1D0J A;  1F3V B;  1LB4 A;  1CA4 A;  1YZE A;  2FOJ A;  3IVV A;  3HQH A;  3MQS C;  4X3G A;  2FOP A;  3ZJB A;  1LB5 A;  1QSC A;  5E1T A;  4GWN A;  4GWM A;  1RF3 A;  1YY6 A;  1D01 A;  3HQI A;  2F1W A;  4M4E A;  1CZZ A;  1K2F A;  1ZMS A;  2GKW A;  3HQL A;  4GJH A;  4C9Z A;  4KG9 A;  1D00 A;  4K8U A;  4JJQ A;  3IVQ A;  2CR2 A;  4O1V A;  4Z8M A;  3HU6 A;  3HSV A;  1LB6 A;  2F1Y A; 
#chains in the Genus database with same CATH homology
 1KZZ A;  1FLK A;  4CA1 A;  1CZY A;  1D0A A;  3HQM A;  4YSI A;  3MQR A;  4I7B A;  2XXN A;  1L0A A;  3IVB A;  5H9M A;  2A25 A;  4GHU A;  2FOO A;  4I7D A;  2AN6 A;  1CA9 A;  2F1Z A;  2F1X A;  4I7C A;  1FLL A;  1D0J A;  1F3V B;  1LB4 A;  1CA4 A;  1YZE A;  2FOJ A;  3IVV A;  3HQH A;  3MQS C;  4X3G A;  2FOP A;  3ZJB A;  1LB5 A;  1QSC A;  5E1T A;  4GWN A;  4GWM A;  1RF3 A;  1YY6 A;  1D01 A;  3HQI A;  2F1W A;  4M4E A;  1CZZ A;  1K2F A;  1ZMS A;  2GKW A;  3HQL A;  4GJH A;  4C9Z A;  4KG9 A;  1D00 A;  4K8U A;  4JJQ A;  3IVQ A;  2CR2 A;  4O1V A;  4Z8M A;  3HU6 A;  3HSV A;  1LB6 A;  2F1Y A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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