1F3VB

Crystal structure of the complex between the n-terminal domain of tradd and the traf domain of traf2
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
171
structure length
171
Chain Sequence
KDLAMADLEQKVLEMEASTYDGVFIWKISDFPRKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQNNREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDLTGL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Apoptosis
source organism Homo sapiens
publication title A novel mechanism of TRAF signaling revealed by structural and functional analyses of the TRADD-TRAF2 interaction.
pubmed doi rcsb
molecule keywords TUMOR NECROSIS FACTOR RECEPTOR TYPE 1 ASSOCIATED DEATH DOMAI
total genus 35
structure length 171
sequence length 171
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2000-06-06
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.210.10 Mainly Beta Sandwich Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A 1f3vB00
2CR2A 4YSIA 2FOJA 4CA1A 1D00A 4GHUA 2F1WA 2F1YA 3HSVA 2FOOA 2XXNA 1CA9A 1F3VB 4X3GA 1FLKA 3HQIA 3HQHA 4C9ZA 1LB4A 2F1ZA 1CA4A 3MQSC 1D0AA 1QSCA 2AN6A 3HU6A 1KZZA 4GWMA 4M4EA 4Z8MA 1LB5A 2GKWA 4JJQA 4KG9A 1K2FA 1CZYA 4I7DA 3HQMA 3HQLA 1L0AA 4I7CA 3IVBA 1YY6A 1FLLA 2F1XA 3MQRA 5H9MA 1D01A 2A25A 3IVVA 3ZJBA 1YZEA 1LB6A 4K8UA 1ZMSA 4I7BA 1RF3A 4O1VA 1D0JA 5E1TA 1CZZA 2FOPA 4GWNA 4GJHA 3IVQA
chains in the Genus database with same CATH superfamily
2CR2A 4YSIA 2FOJA 4CA1A 1D00A 4GHUA 2F1WA 2F1YA 3HSVA 2FOOA 2XXNA 1CA9A 1F3VB 4X3GA 1FLKA 3HQIA 3HQHA 4C9ZA 1LB4A 2F1ZA 1CA4A 3MQSC 1D0AA 1QSCA 2AN6A 3HU6A 1KZZA 4GWMA 4M4EA 4Z8MA 1LB5A 2GKWA 4JJQA 4KG9A 1K2FA 1CZYA 4I7DA 3HQMA 3HQLA 1L0AA 4I7CA 3IVBA 1YY6A 1FLLA 2F1XA 3MQRA 5H9MA 1D01A 2A25A 3IVVA 3ZJBA 1YZEA 1LB6A 4K8UA 1ZMSA 4I7BA 1RF3A 4O1VA 1D0JA 5E1TA 1CZZA 2FOPA 4GWNA 4GJHA 3IVQA
chains in the Genus database with same CATH topology
2CR2A 4YSIA 2FOJA 4CA1A 1D00A 4GHUA 2F1WA 2F1YA 3HSVA 2FOOA 2XXNA 1CA9A 1F3VB 4X3GA 1FLKA 3HQIA 3HQHA 4C9ZA 1LB4A 2F1ZA 1CA4A 3MQSC 1D0AA 1QSCA 2AN6A 3HU6A 1KZZA 4GWMA 4M4EA 4Z8MA 1LB5A 2GKWA 4JJQA 4KG9A 1K2FA 1CZYA 4I7DA 3HQMA 3HQLA 1L0AA 4I7CA 3IVBA 1YY6A 1FLLA 2F1XA 3MQRA 5H9MA 1D01A 2A25A 3IVVA 3ZJBA 1YZEA 1LB6A 4K8UA 1ZMSA 4I7BA 1RF3A 4O1VA 1D0JA 5E1TA 1CZZA 2FOPA 4GWNA 4GJHA 3IVQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2CR2 A;  4YSI A;  2FOJ A;  4CA1 A;  1D00 A;  4GHU A;  2F1W A;  2F1Y A;  3HSV A;  2FOO A;  2XXN A;  1CA9 A;  1F3V B;  4X3G A;  1FLK A;  3HQI A;  3HQH A;  4C9Z A;  1LB4 A;  2F1Z A;  1CA4 A;  3MQS C;  1D0A A;  1QSC A;  2AN6 A;  3HU6 A;  1KZZ A;  4GWM A;  4M4E A;  4Z8M A;  1LB5 A;  2GKW A;  4JJQ A;  4KG9 A;  1K2F A;  1CZY A;  4I7D A;  3HQM A;  3HQL A;  1L0A A;  4I7C A;  3IVB A;  1YY6 A;  1FLL A;  2F1X A;  3MQR A;  5H9M A;  1D01 A;  2A25 A;  3IVV A;  3ZJB A;  1YZE A;  1LB6 A;  4K8U A;  1ZMS A;  4I7B A;  1RF3 A;  4O1V A;  1D0J A;  5E1T A;  1CZZ A;  2FOP A;  4GWN A;  4GJH A;  3IVQ A; 
#chains in the Genus database with same CATH topology
 2CR2 A;  4YSI A;  2FOJ A;  4CA1 A;  1D00 A;  4GHU A;  2F1W A;  2F1Y A;  3HSV A;  2FOO A;  2XXN A;  1CA9 A;  1F3V B;  4X3G A;  1FLK A;  3HQI A;  3HQH A;  4C9Z A;  1LB4 A;  2F1Z A;  1CA4 A;  3MQS C;  1D0A A;  1QSC A;  2AN6 A;  3HU6 A;  1KZZ A;  4GWM A;  4M4E A;  4Z8M A;  1LB5 A;  2GKW A;  4JJQ A;  4KG9 A;  1K2F A;  1CZY A;  4I7D A;  3HQM A;  3HQL A;  1L0A A;  4I7C A;  3IVB A;  1YY6 A;  1FLL A;  2F1X A;  3MQR A;  5H9M A;  1D01 A;  2A25 A;  3IVV A;  3ZJB A;  1YZE A;  1LB6 A;  4K8U A;  1ZMS A;  4I7B A;  1RF3 A;  4O1V A;  1D0J A;  5E1T A;  1CZZ A;  2FOP A;  4GWN A;  4GJH A;  3IVQ A; 
#chains in the Genus database with same CATH homology
 2CR2 A;  4YSI A;  2FOJ A;  4CA1 A;  1D00 A;  4GHU A;  2F1W A;  2F1Y A;  3HSV A;  2FOO A;  2XXN A;  1CA9 A;  1F3V B;  4X3G A;  1FLK A;  3HQI A;  3HQH A;  4C9Z A;  1LB4 A;  2F1Z A;  1CA4 A;  3MQS C;  1D0A A;  1QSC A;  2AN6 A;  3HU6 A;  1KZZ A;  4GWM A;  4M4E A;  4Z8M A;  1LB5 A;  2GKW A;  4JJQ A;  4KG9 A;  1K2F A;  1CZY A;  4I7D A;  3HQM A;  3HQL A;  1L0A A;  4I7C A;  3IVB A;  1YY6 A;  1FLL A;  2F1X A;  3MQR A;  5H9M A;  1D01 A;  2A25 A;  3IVV A;  3ZJB A;  1YZE A;  1LB6 A;  4K8U A;  1ZMS A;  4I7B A;  1RF3 A;  4O1V A;  1D0J A;  5E1T A;  1CZZ A;  2FOP A;  4GWN A;  4GJH A;  3IVQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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