1GJHA

Human bcl-2, isoform 2
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
164
structure length
164
Chain Sequence
HAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDDVEENRTEAPEGTESEVVHLTLRQAGDDFSRRYRRDFAEMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYGPSMR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of the antiapoptotic protein bcl-2.
pubmed doi rcsb
molecule tags Apoptosis
source organism Homo sapiens
molecule keywords PROTEIN (APOPTOSIS REGULATOR BCL-2 WITH PUTATIVE FLEXIBLE LO
total genus 38
structure length 164
sequence length 164
ec nomenclature
pdb deposition date 2001-05-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00452 Bcl-2 Apoptosis regulator proteins, Bcl-2 family
A PF02180 BH4 Bcl-2 homology region 4
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.437.10 Mainly Alpha Orthogonal Bundle Apoptosis Regulator Bcl-x Blc2-like 1gjhA00
4ZIGA 3KZ0A 3KJ1A 4HW4A 2VOFA 2NLAA 4BDUA 1Q59A 2ABOA 1YSGA 2RODA 2O2NA 2V6QA 1YSIA 2ME8A 2VOHA 2O22A 2O2FA 4WMRA 5IF4A 1PQ1A 5KU9A 4OQ5A 2LR1A 1R2DA 1DDBA 3PK1A 1G5MA 2W3LA 4BPJA 3WIYA 2WH6A 2O2MA 3IIGA 1R2GA 2K7WA 5FDOA 2KBWA 1R2EA 2XPXA 4YJ4A 5FMIA 3KJ0A 1MAZA 3D7VA 2YV6A 1LXLA 4MI8A 4ZIIA 4QVXA 3QBRA 2VOGA 5JSBA 3IIHA 1O0LA 4OQ6A 2BIDA 4BD6A 4BD7A 2M5BA 4YK9A 3KJ2A 4BPIA 5C3FA 1F16A 4BD8A 2B48A 4S0PA 1YSNA 1TY4A 3MK8A 1WSXA 2O21A 4ZIHA 2ROCA 4QNQA 4B4SA 2A5YA 4ZEQA 4U2UA 4ZBFA 3IHDA 3MQPA 1R2HA 2IMSA 4ZBIA 3IHEA 4HW3A 1AF3A 2IMTA 2VM6A 3CVAX 1BXLA 5KTGA 1GJHA 4HW2A 3DVUA 2JM6B 4BD2A 3IHCA 1ZY3A 1R2IA 2XA0A 5FC4A 4S0OA 4K5BC 3I1HA 2MHSA 2KUAA 1K3KA 3ILCA 1MK3A 2MEJA 2VOIA 4OYDA 4ZIFA 1YSWA 4G35A 1PQ0A 2NL9A 5FDRA 1OHUA 3WIXA 3BL2A 2BZWA 5C6HA 3IO9A 2JCNA 4U2VA 4ZIEA 2PQKA 5IEZA 1G5JA
chains in the Genus database with same CATH superfamily
4ZIGA 3KZ0A 3KJ1A 4HW4A 2VOFA 2NLAA 4BDUA 1Q59A 2ABOA 1YSGA 2RODA 4UF1A 2O2NA 2V6QA 1YSIA 2ME8A 2VOHA 2O22A 4D2MA 4LQKA 2O2FA 4WMRA 5IF4A 1PQ1A 5KU9A 4OQ5A 2LR1A 1R2DA 4BBCA 1DDBA 3PK1A 1G5MA 2W3LA 4BPJA 3WIYA 2WH6A 2O2MA 3IIGA 1R2GA 2JBXA 2K36A 2K7WA 5FDOA 2KBWA 1R2EA 2XPXA 4YJ4A 3JRVA 4D2LA 5FMIA 3KJ0A 1MAZA 3D7VA 2YV6A 1LXLA 4MI8A 2O42A 4ZIIA 4QVXA 3QBRA 2VOGA 5JSBA 3IIHA 1O0LA 4OQ6A 2BIDA 4BBDA 4BD6A 4BD7A 2M5BA 2I39A 4YK9A 3KJ2A 4BPIA 5C3FA 1F16A 4BD8A 2VVYA 2B48A 4S0PA 1YSNA 1TY4A 3MK8A 1WSXA 2O21A 4ZIHA 2JBYA 2ROCA 4QNQA 4B4SA 2A5YA 4ZEQA 4U2UA 4UF3A 4ZBFA 3IHDA 3MQPA 1R2HA 2IMSA 4ZBIA 3IHEA 4HW3A 1AF3A 2IMTA 2VM6A 3CVAX 1BXLA 5KTGA 1GJHA 4HW2A 3DVUA 2JM6B 4BD2A 1ZY3A 3IHCA 1R2IA 2XA0A 5FC4A 4S0OA 4K5BC 3I1HA 2MHSA 2KUAA 4M0SA 1K3KA 2VOIA 1MK3A 2MEJA 3ILCA 4OYDA 4ZIFA 1YSWA 4G35A 1PQ0A 2NL9A 2VTYA 5FDRA 1OHUA 3WIXA 3BL2A 4BBBA 2BZWA 4UF2A 2VVXA 5C6HA 3IO9A 2UXEA 2JCNA 4U2VA 4ZIEA 2PQKA 5IEZA 2VVWA 1G5JA
chains in the Genus database with same CATH topology
4ZIGA 3KZ0A 3KJ1A 4HW4A 2VOFA 2NLAA 4BDUA 1Q59A 2ABOA 1YSGA 2RODA 2O2NA 2V6QA 1YSIA 2ME8A 2VOHA 2O22A 2O2FA 4WMRA 5IF4A 1PQ1A 5KU9A 4OQ5A 2LR1A 1R2DA 1DDBA 3PK1A 1G5MA 2W3LA 4BPJA 3WIYA 2WH6A 2O2MA 3IIGA 1R2GA 2K7WA 5FDOA 2KBWA 1R2EA 2XPXA 4YJ4A 5FMIA 3KJ0A 1MAZA 3D7VA 2YV6A 1LXLA 4MI8A 4ZIIA 4QVXA 3QBRA 2VOGA 5JSBA 3IIHA 1O0LA 4OQ6A 2BIDA 4BD6A 4BD7A 2M5BA 4YK9A 3KJ2A 4BPIA 5C3FA 1F16A 4BD8A 2B48A 4S0PA 1YSNA 1TY4A 3MK8A 1WSXA 2O21A 4ZIHA 2ROCA 4QNQA 4B4SA 2A5YA 4ZEQA 4U2UA 4ZBFA 3IHDA 3MQPA 1R2HA 2IMSA 4ZBIA 3IHEA 4HW3A 1AF3A 2IMTA 2VM6A 3CVAX 1BXLA 5KTGA 1GJHA 4HW2A 3DVUA 2JM6B 4BD2A 3IHCA 1ZY3A 1R2IA 2XA0A 5FC4A 4S0OA 4K5BC 3I1HA 2MHSA 2KUAA 1K3KA 3ILCA 1MK3A 2MEJA 2VOIA 4OYDA 4ZIFA 1YSWA 4G35A 1PQ0A 2NL9A 5FDRA 1OHUA 3WIXA 3BL2A 2BZWA 5C6HA 3IO9A 2JCNA 4U2VA 4ZIEA 2PQKA 5IEZA 1G5JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ZIG A;  3KZ0 A;  3KJ1 A;  4HW4 A;  2VOF A;  2NLA A;  4BDU A;  1Q59 A;  2ABO A;  1YSG A;  2ROD A;  2O2N A;  2V6Q A;  1YSI A;  2ME8 A;  2VOH A;  2O22 A;  2O2F A;  4WMR A;  5IF4 A;  1PQ1 A;  5KU9 A;  4OQ5 A;  2LR1 A;  1R2D A;  1DDB A;  3PK1 A;  1G5M A;  2W3L A;  4BPJ A;  3WIY A;  2WH6 A;  2O2M A;  3IIG A;  1R2G A;  2K7W A;  5FDO A;  2KBW A;  1R2E A;  2XPX A;  4YJ4 A;  5FMI A;  3KJ0 A;  1MAZ A;  3D7V A;  2YV6 A;  1LXL A;  4MI8 A;  4ZII A;  4QVX A;  3QBR A;  2VOG A;  5JSB A;  3IIH A;  1O0L A;  4OQ6 A;  2BID A;  4BD6 A;  4BD7 A;  2M5B A;  4YK9 A;  3KJ2 A;  4BPI A;  5C3F A;  1F16 A;  4BD8 A;  2B48 A;  4S0P A;  1YSN A;  1TY4 A;  3MK8 A;  1WSX A;  2O21 A;  4ZIH A;  2ROC A;  4QNQ A;  4B4S A;  2A5Y A;  4ZEQ A;  4U2U A;  4ZBF A;  3IHD A;  3MQP A;  1R2H A;  2IMS A;  4ZBI A;  3IHE A;  4HW3 A;  1AF3 A;  2IMT A;  2VM6 A;  3CVA X;  1BXL A;  5KTG A;  1GJH A;  4HW2 A;  3DVU A;  2JM6 B;  4BD2 A;  3IHC A;  1ZY3 A;  1R2I A;  2XA0 A;  5FC4 A;  4S0O A;  4K5B C;  3I1H A;  2MHS A;  2KUA A;  1K3K A;  3ILC A;  1MK3 A;  2MEJ A;  2VOI A;  4OYD A;  4ZIF A;  1YSW A;  4G35 A;  1PQ0 A;  2NL9 A;  5FDR A;  1OHU A;  3WIX A;  3BL2 A;  2BZW A;  5C6H A;  3IO9 A;  2JCN A;  4U2V A;  4ZIE A;  2PQK A;  5IEZ A;  1G5J A; 
#chains in the Genus database with same CATH topology
 4ZIG A;  3KZ0 A;  3KJ1 A;  4HW4 A;  2VOF A;  2NLA A;  4BDU A;  1Q59 A;  2ABO A;  1YSG A;  2ROD A;  4UF1 A;  2O2N A;  2V6Q A;  1YSI A;  2ME8 A;  2VOH A;  2O22 A;  4D2M A;  4LQK A;  2O2F A;  4WMR A;  5IF4 A;  1PQ1 A;  5KU9 A;  4OQ5 A;  2LR1 A;  1R2D A;  4BBC A;  1DDB A;  3PK1 A;  1G5M A;  2W3L A;  4BPJ A;  3WIY A;  2WH6 A;  2O2M A;  3IIG A;  1R2G A;  2JBX A;  2K36 A;  2K7W A;  5FDO A;  2KBW A;  1R2E A;  2XPX A;  4YJ4 A;  3JRV A;  4D2L A;  5FMI A;  3KJ0 A;  1MAZ A;  3D7V A;  2YV6 A;  1LXL A;  4MI8 A;  2O42 A;  4ZII A;  4QVX A;  3QBR A;  2VOG A;  5JSB A;  3IIH A;  1O0L A;  4OQ6 A;  2BID A;  4BBD A;  4BD6 A;  4BD7 A;  2M5B A;  2I39 A;  4YK9 A;  3KJ2 A;  4BPI A;  5C3F A;  1F16 A;  4BD8 A;  2VVY A;  2B48 A;  4S0P A;  1YSN A;  1TY4 A;  3MK8 A;  1WSX A;  2O21 A;  4ZIH A;  2JBY A;  2ROC A;  4QNQ A;  4B4S A;  2A5Y A;  4ZEQ A;  4U2U A;  4UF3 A;  4ZBF A;  3IHD A;  3MQP A;  1R2H A;  2IMS A;  4ZBI A;  3IHE A;  4HW3 A;  1AF3 A;  2IMT A;  2VM6 A;  3CVA X;  1BXL A;  5KTG A;  1GJH A;  4HW2 A;  3DVU A;  2JM6 B;  4BD2 A;  1ZY3 A;  3IHC A;  1R2I A;  2XA0 A;  5FC4 A;  4S0O A;  4K5B C;  3I1H A;  2MHS A;  2KUA A;  4M0S A;  1K3K A;  2VOI A;  1MK3 A;  2MEJ A;  3ILC A;  4OYD A;  4ZIF A;  1YSW A;  4G35 A;  1PQ0 A;  2NL9 A;  2VTY A;  5FDR A;  1OHU A;  3WIX A;  3BL2 A;  4BBB A;  2BZW A;  4UF2 A;  2VVX A;  5C6H A;  3IO9 A;  2UXE A;  2JCN A;  4U2V A;  4ZIE A;  2PQK A;  5IEZ A;  2VVW A;  1G5J A; 
#chains in the Genus database with same CATH homology
 4ZIG A;  3KZ0 A;  3KJ1 A;  4HW4 A;  2VOF A;  2NLA A;  4BDU A;  1Q59 A;  2ABO A;  1YSG A;  2ROD A;  2O2N A;  2V6Q A;  1YSI A;  2ME8 A;  2VOH A;  2O22 A;  2O2F A;  4WMR A;  5IF4 A;  1PQ1 A;  5KU9 A;  4OQ5 A;  2LR1 A;  1R2D A;  1DDB A;  3PK1 A;  1G5M A;  2W3L A;  4BPJ A;  3WIY A;  2WH6 A;  2O2M A;  3IIG A;  1R2G A;  2K7W A;  5FDO A;  2KBW A;  1R2E A;  2XPX A;  4YJ4 A;  5FMI A;  3KJ0 A;  1MAZ A;  3D7V A;  2YV6 A;  1LXL A;  4MI8 A;  4ZII A;  4QVX A;  3QBR A;  2VOG A;  5JSB A;  3IIH A;  1O0L A;  4OQ6 A;  2BID A;  4BD6 A;  4BD7 A;  2M5B A;  4YK9 A;  3KJ2 A;  4BPI A;  5C3F A;  1F16 A;  4BD8 A;  2B48 A;  4S0P A;  1YSN A;  1TY4 A;  3MK8 A;  1WSX A;  2O21 A;  4ZIH A;  2ROC A;  4QNQ A;  4B4S A;  2A5Y A;  4ZEQ A;  4U2U A;  4ZBF A;  3IHD A;  3MQP A;  1R2H A;  2IMS A;  4ZBI A;  3IHE A;  4HW3 A;  1AF3 A;  2IMT A;  2VM6 A;  3CVA X;  1BXL A;  5KTG A;  1GJH A;  4HW2 A;  3DVU A;  2JM6 B;  4BD2 A;  3IHC A;  1ZY3 A;  1R2I A;  2XA0 A;  5FC4 A;  4S0O A;  4K5B C;  3I1H A;  2MHS A;  2KUA A;  1K3K A;  3ILC A;  1MK3 A;  2MEJ A;  2VOI A;  4OYD A;  4ZIF A;  1YSW A;  4G35 A;  1PQ0 A;  2NL9 A;  5FDR A;  1OHU A;  3WIX A;  3BL2 A;  2BZW A;  5C6H A;  3IO9 A;  2JCN A;  4U2V A;  4ZIE A;  2PQK A;  5IEZ A;  1G5J A; 
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similar chains in the pdb database (?% sequence similarity)

 
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