1GJJA

N-terminal constant region of the nuclear envelope protein lap2
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
Knots found
sequence length
153
structure length
93
Chain Sequence
MPEFLEDPSVLTKDKLKSELVANNVTLPAGEQRKDVYVQLYLQHLTARNRDVTELTNEDLLDQLVKYGVNPGPIVGTTRKLYEKKLLKLREQG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of the constant region of nuclear envelope protein LAP2 reveals two LEM-domain structures: one binds BAF and the other binds DNA.
pubmed doi rcsb
molecule tags Membrane protein
source organism Homo sapiens
molecule keywords LAP2
total genus 42
structure length 93
sequence length 153
other databases KnotProt 2.0: Artifct S 7.4 51 +3.
ec nomenclature
pdb deposition date 2001-06-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03020 LEM LEM domain
A PF08198 Thymopoietin Thymopoietin protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.720.40 Mainly Alpha Orthogonal Bundle Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 1gjjA00
2ODGC 2ODCI 1JEIA 1H9FA 1GJJA 1H9EA
chains in the Genus database with same CATH superfamily
2A8VA 2QNCA 2W51A 1JEIA 1H9FA 1KHCA 2JVWA 2G80A 3L0OA 1A63A 1GJJA 1H9EA 2ODGC 4BITA 2LD7A 2HJQA 1GL9B 2KVUA 1ZBHA 1E7DA 1E7LA 2KFVA 1JEQA 2LC3A 2WQGA 1JJRA 2RNOA 2ODCI 1H1JS 2KW9A 2KVEA 3FLGA 1GKUB 2RNNA 2MPHA 2KVDA 1EN7A 1V66A 1ZS9A 2QNFA 4UZWA 1Y02A 3QKJA 1YNSA 1A8VA 1A62A 3LLRA 5CIUA 2DK4A
chains in the Genus database with same CATH topology
2A8VA 2QNCA 2W51A 1JEIA 1H9FA 3L0OA 2G80A 1A63A 1GJJA 1H9EA 2ODGC 2LD7A 2HJQA 1GL9B 1E7DA 1E7LA 2KFVA 2LC3A 2ODCI 1GKUB 2MPHA 1EN7A 1ZS9A 2QNFA 1Y02A 1YNSA 1A8VA 1A62A 2DK4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ODG C;  2ODC I;  1JEI A;  1H9F A;  1GJJ A;  1H9E A; 
#chains in the Genus database with same CATH topology
 2A8V A;  2QNC A;  2W51 A;  1JEI A;  1H9F A;  1KHC A;  2JVW A;  2G80 A;  3L0O A;  1A63 A;  1GJJ A;  1H9E A;  2ODG C;  4BIT A;  2LD7 A;  2HJQ A;  1GL9 B;  2KVU A;  1ZBH A;  1E7D A;  1E7L A;  2KFV A;  1JEQ A;  2LC3 A;  2WQG A;  1JJR A;  2RNO A;  2ODC I;  1H1J S;  2KW9 A;  2KVE A;  3FLG A;  1GKU B;  2RNN A;  2MPH A;  2KVD A;  1EN7 A;  1V66 A;  1ZS9 A;  2QNF A;  4UZW A;  1Y02 A;  3QKJ A;  1YNS A;  1A8V A;  1A62 A;  3LLR A;  5CIU A;  2DK4 A; 
#chains in the Genus database with same CATH homology
 2A8V A;  2QNC A;  2W51 A;  1JEI A;  1H9F A;  3L0O A;  2G80 A;  1A63 A;  1GJJ A;  1H9E A;  2ODG C;  2LD7 A;  2HJQ A;  1GL9 B;  1E7D A;  1E7L A;  2KFV A;  2LC3 A;  2ODC I;  1GKU B;  2MPH A;  1EN7 A;  1ZS9 A;  2QNF A;  1Y02 A;  1YNS A;  1A8V A;  1A62 A;  2DK4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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