1GJJA

N-terminal constant region of the nuclear envelope protein lap2
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
Knots found
sequence length
153
structure length
93
Chain Sequence
MPEFLEDPSVLTKDKLKSELVANNVTLPAGEQRKDVYVQLYLQHLTARNRDVTELTNEDLLDQLVKYGVNPGPIVGTTRKLYEKKLLKLREQG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of the constant region of nuclear envelope protein LAP2 reveals two LEM-domain structures: one binds BAF and the other binds DNA.
pubmed doi rcsb
molecule tags Membrane protein
source organism Homo sapiens
molecule keywords LAP2
total genus 42
structure length 93
sequence length 153
other databases KnotProt 2.0: Artifct S 7.4 51 +3.
ec nomenclature
pdb deposition date 2001-06-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03020 LEM LEM domain
A PF08198 Thymopoietin Thymopoietin protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.720.40 Mainly Alpha Orthogonal Bundle Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 1gjjA00
1H9EA 2ODGC 1GJJA 2ODCI 1JEIA 1H9FA
chains in the Genus database with same CATH superfamily
4UZWA 2G80A 2KFVA 2JVWA 2KW9A 2LC3A 1GKUB 1A63A 1GL9B 2W51A 2RNOA 1E7LA 3FLGA 2QNCA 2KVDA 3QKJA 1ZS9A 2ODGC 1Y02A 1GJJA 5CIUA 1JEQA 2DK4A 1E7DA 1ZBHA 2A8VA 2MPHA 1JEIA 2LD7A 1V66A 1YNSA 1A62A 1H9EA 2WQGA 3LLRA 2KVUA 2QNFA 3L0OA 1JJRA 2ODCI 2HJQA 2KVEA 2RNNA 4BITA 1H1JS 1KHCA 1H9FA 1A8VA 1EN7A
chains in the Genus database with same CATH topology
2G80A 2KFVA 2LC3A 1GKUB 1A63A 1GL9B 2W51A 1E7LA 2QNCA 1ZS9A 2ODGC 1Y02A 1GJJA 2DK4A 1E7DA 2A8VA 2MPHA 1JEIA 2LD7A 1YNSA 1A62A 1H9EA 2QNFA 3L0OA 2ODCI 2HJQA 1H9FA 1A8VA 1EN7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1H9E A;  2ODG C;  1GJJ A;  2ODC I;  1JEI A;  1H9F A; 
#chains in the Genus database with same CATH topology
 4UZW A;  2G80 A;  2KFV A;  2JVW A;  2KW9 A;  2LC3 A;  1GKU B;  1A63 A;  1GL9 B;  2W51 A;  2RNO A;  1E7L A;  3FLG A;  2QNC A;  2KVD A;  3QKJ A;  1ZS9 A;  2ODG C;  1Y02 A;  1GJJ A;  5CIU A;  1JEQ A;  2DK4 A;  1E7D A;  1ZBH A;  2A8V A;  2MPH A;  1JEI A;  2LD7 A;  1V66 A;  1YNS A;  1A62 A;  1H9E A;  2WQG A;  3LLR A;  2KVU A;  2QNF A;  3L0O A;  1JJR A;  2ODC I;  2HJQ A;  2KVE A;  2RNN A;  4BIT A;  1H1J S;  1KHC A;  1H9F A;  1A8V A;  1EN7 A; 
#chains in the Genus database with same CATH homology
 2G80 A;  2KFV A;  2LC3 A;  1GKU B;  1A63 A;  1GL9 B;  2W51 A;  1E7L A;  2QNC A;  1ZS9 A;  2ODG C;  1Y02 A;  1GJJ A;  2DK4 A;  1E7D A;  2A8V A;  2MPH A;  1JEI A;  2LD7 A;  1YNS A;  1A62 A;  1H9E A;  2QNF A;  3L0O A;  2ODC I;  2HJQ A;  1H9F A;  1A8V A;  1EN7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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