1GJJA

N-terminal constant region of the nuclear envelope protein lap2
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
Knots found
sequence length
153
structure length
93
Chain Sequence
MPEFLEDPSVLTKDKLKSELVANNVTLPAGEQRKDVYVQLYLQHLTARNRDVTELTNEDLLDQLVKYGVNPGPIVGTTRKLYEKKLLKLREQG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of the constant region of nuclear envelope protein LAP2 reveals two LEM-domain structures: one binds BAF and the other binds DNA.
pubmed doi rcsb
molecule keywords LAP2
molecule tags Membrane protein
source organism Homo sapiens
total genus 42
structure length 93
sequence length 153
other databases KnotProt 2.0: Artifct S 7.4 51 +3.
ec nomenclature
pdb deposition date 2001-06-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03020 LEM LEM domain
A PF08198 Thymopoietin Thymopoietin protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.720.40 Mainly Alpha Orthogonal Bundle Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 1gjjA00
1GJJA 2ODGC 1H9EA 1H9FA 1JEIA 2ODCI
chains in the Genus database with same CATH superfamily
2W51A 1E7LA 2G80A 1E7DA 2MPHA 2RNNA 2QNCA 3QKJA 2LD7A 2HJQA 2WQGA 2LC3A 2KVEA 1V66A 2KVDA 1Y02A 1JEQA 1A62A 2QNFA 1A63A 1YNSA 1KHCA 2KW9A 3FLGA 1GJJA 2ODGC 3LLRA 1EN7A 1H9FA 1JEIA 2DK4A 2JVWA 1ZBHA 1H1JS 2KVUA 1A8VA 4UZWA 3L0OA 1H9EA 1JJRA 2A8VA 2RNOA 4BITA 1ZS9A 5CIUA 2KFVA 1GL9B 2ODCI 1GKUB
chains in the Genus database with same CATH topology
2W51A 1E7LA 2G80A 1E7DA 2MPHA 2QNCA 2LD7A 2HJQA 2LC3A 1Y02A 2QNFA 1A62A 1A63A 1YNSA 1GJJA 2ODGC 1EN7A 1H9FA 1JEIA 2DK4A 1A8VA 1H9EA 3L0OA 2A8VA 1ZS9A 2KFVA 1GL9B 2ODCI 1GKUB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GJJ A;  2ODG C;  1H9E A;  1H9F A;  1JEI A;  2ODC I; 
#chains in the Genus database with same CATH topology
 2W51 A;  1E7L A;  2G80 A;  1E7D A;  2MPH A;  2RNN A;  2QNC A;  3QKJ A;  2LD7 A;  2HJQ A;  2WQG A;  2LC3 A;  2KVE A;  1V66 A;  2KVD A;  1Y02 A;  1JEQ A;  1A62 A;  2QNF A;  1A63 A;  1YNS A;  1KHC A;  2KW9 A;  3FLG A;  1GJJ A;  2ODG C;  3LLR A;  1EN7 A;  1H9F A;  1JEI A;  2DK4 A;  2JVW A;  1ZBH A;  1H1J S;  2KVU A;  1A8V A;  4UZW A;  3L0O A;  1H9E A;  1JJR A;  2A8V A;  2RNO A;  4BIT A;  1ZS9 A;  5CIU A;  2KFV A;  1GL9 B;  2ODC I;  1GKU B; 
#chains in the Genus database with same CATH homology
 2W51 A;  1E7L A;  2G80 A;  1E7D A;  2MPH A;  2QNC A;  2LD7 A;  2HJQ A;  2LC3 A;  1Y02 A;  2QNF A;  1A62 A;  1A63 A;  1YNS A;  1GJJ A;  2ODG C;  1EN7 A;  1H9F A;  1JEI A;  2DK4 A;  1A8V A;  1H9E A;  3L0O A;  2A8V A;  1ZS9 A;  2KFV A;  1GL9 B;  2ODC I;  1GKU B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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