1GTP | Genus

Total Genus 63

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	63
sequence length	221
structure length	221
Chain Sequence	PSLSKEAALVHEALVARGLETPLRPPVHEMDNETRKSLIAGHMTEIMQLLNLDLADDSLMETPHRIAKMYVDEIFSGLDYANFPKITLIENKMKVDEMVTVRDITLTSTCEHHFVTIDGKATVAYIPKDSVIGLSKINRIVQFFAQRPQVQERLTQQILIALQTLLGTNNVAVSIDAVHYCVKARGIRDATSATTTTSLGGLFKSSQNTRHEFLRAVRHHN

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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reading 221 atoms

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221 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Atomic structure of GTP cyclohydrolase I. pubmed doi rcsb
molecule keywords	GTP CYCLOHYDROLASE I
molecule tags	Hydrolase
source organism	Escherichia coli
total genus	63
structure length	221
sequence length	221
chains with identical sequence	B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T
ec nomenclature	ec 3.5.4.16: GTP cyclohydrolase I.
pdb deposition date	1995-09-16

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01227	GTP_cyclohydroI	GTP cyclohydrolase I

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.286.10	Mainly Alpha	Orthogonal Bundle	GTP Cyclohydrolase I; Chain A, domain 1	GTP Cyclohydrolase I; Chain A, domain 1	1gtpA01
3.30.1130.10	Alpha Beta	2-Layer Sandwich	GTP Cyclohydrolase I, domain 2	GTP Cyclohydrolase I, domain 2	1gtpA02

2NM2A 1IS7A 1Z9WA 3BP1A 4FGCA 1N3RA 1A8RA 5FARA 1N3SA 1A9CA 1RSDA 1RRIA 4UQFA 3S19A 1RRYA 1NBUA 4DU6A 2DHNA 1FBXA 1WM9A 3RZPA 1NBUC 2NM3A 1NBUB 4GHMA 1N3TA 1FB1A 4F8BA 3UXVA 1WUQA 1IS8A 1RSIA 1RS4A 3V9OA 3R2EA 1DHNA 1U68A 1RS2A 4AEYA 1WURA 1RRWA 2O90A 2CG8A 1GTPA 1SQLA 5F3MA 1WPLA 3O1KA 1B9LA 3UXJA 4IQIA 3RJ4A
chains in the Genus database with same CATH superfamily

3B0BC 2PN0A 2O01G 2WSCG 1NBUC 4JA3A 3LW5K 2WSEG 2CG8A 3UXJA 4E45B 4IQIA 2NM2A 1IS7A 1Z9WA 4FGCA 1A9CA 3S19A 1RRYA 2WSFG 2LO0A 4QPMA 1NBUA 4DU6A 2DHNA 3RZPA 2NM3A 1N3TA 1FB1A 3VEJA 3R2EA 1RS2A 4AEYA 1WURA 1RRWA 5F3MA 4NE6B 3O1KA 4NE5B 3BMBA 5FARA 5DMZA 1RSDA 1RRIA 2KR1A 2WSCK 4GHMA 3UXVA 1RSIA 3V9OA 1TFEA 2WSEK 1DHNA 1U68A 4E44B 2O90A 1SQLA 1WPLA 4NE3B 1AIPC 3RJ4A 3BP1A 1N3RA 4Q7JA 2P11A 1A8RA 1EFUB 4DRBJ 1N3SA 4R8QA 2WSFK 4UQFA 1EL6A 1FBXA 1WM9A 1NBUB 4F8BA 1WUQA 1IS8A 4DRAE 1RS4A 2LNZA 1GTPA 3LW5G 1B9LA
chains in the Genus database with same CATH topology

2NM2A 4NE5B 1IS7A 3B0BC 1Z9WA 3BP1A 4FGCA 1N3RA 4Q7JA 3BMBA 2P11A 1A8RA 1EFUB 4DRBJ 5FARA 1N3SA 1A9CA 4R8QA 5DMZA 1RSDA 2PN0A 1RRIA 2KR1A 4UQFA 3S19A 1RRYA 1EL6A 2LO0A 4QPMA 1NBUA 4DU6A 2DHNA 1FBXA 1WM9A 3RZPA 1NBUC 2NM3A 4JA3A 1NBUB 4GHMA 1N3TA 1FB1A 4F8BA 3UXVA 1WUQA 1IS8A 3VEJA 4DRAE 1RSIA 1RS4A 3V9OA 1TFEA 2LNZA 3R2EA 1DHNA 1U68A 1RS2A 4AEYA 1WURA 4E44B 1RRWA 2O90A 2CG8A 1GTPA 4NE6B 1SQLA 5F3MA 1WPLA 4NE3B 1B9LA 3O1KA 1AIPC 3UXJA 4E45B 4IQIA 3RJ4A
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 2NM2 A;  1IS7 A;  1Z9W A;  3BP1 A;  4FGC A;  1N3R A;  1A8R A;  5FAR A;  1N3S A;  1A9C A;  1RSD A;  1RRI A;  4UQF A;  3S19 A;  1RRY A;  1NBU A;  4DU6 A;  2DHN A;  1FBX A;  1WM9 A;  3RZP A;  1NBU C;  2NM3 A;  1NBU B;  4GHM A;  1N3T A;  1FB1 A;  4F8B A;  3UXV A;  1WUQ A;  1IS8 A;  1RSI A;  1RS4 A;  3V9O A;  3R2E A;  1DHN A;  1U68 A;  1RS2 A;  4AEY A;  1WUR A;  1RRW A;  2O90 A;  2CG8 A;  1GTP A;  1SQL A;  5F3M A;  1WPL A;  3O1K A;  1B9L A;  3UXJ A;  4IQI A;  3RJ4 A; 
#chains in the Genus database with same CATH topology
 3B0B C;  2PN0 A;  2O01 G;  2WSC G;  1NBU C;  4JA3 A;  3LW5 K;  2WSE G;  2CG8 A;  3UXJ A;  4E45 B;  4IQI A;  2NM2 A;  1IS7 A;  1Z9W A;  4FGC A;  1A9C A;  3S19 A;  1RRY A;  2WSF G;  2LO0 A;  4QPM A;  1NBU A;  4DU6 A;  2DHN A;  3RZP A;  2NM3 A;  1N3T A;  1FB1 A;  3VEJ A;  3R2E A;  1RS2 A;  4AEY A;  1WUR A;  1RRW A;  5F3M A;  4NE6 B;  3O1K A;  4NE5 B;  3BMB A;  5FAR A;  5DMZ A;  1RSD A;  1RRI A;  2KR1 A;  2WSC K;  4GHM A;  3UXV A;  1RSI A;  3V9O A;  1TFE A;  2WSE K;  1DHN A;  1U68 A;  4E44 B;  2O90 A;  1SQL A;  1WPL A;  4NE3 B;  1AIP C;  3RJ4 A;  3BP1 A;  1N3R A;  4Q7J A;  2P11 A;  1A8R A;  1EFU B;  4DRB J;  1N3S A;  4R8Q A;  2WSF K;  4UQF A;  1EL6 A;  1FBX A;  1WM9 A;  1NBU B;  4F8B A;  1WUQ A;  1IS8 A;  4DRA E;  1RS4 A;  2LNZ A;  1GTP A;  3LW5 G;  1B9L A; 
#chains in the Genus database with same CATH homology
 2NM2 A;  4NE5 B;  1IS7 A;  3B0B C;  1Z9W A;  3BP1 A;  4FGC A;  1N3R A;  4Q7J A;  3BMB A;  2P11 A;  1A8R A;  1EFU B;  4DRB J;  5FAR A;  1N3S A;  1A9C A;  4R8Q A;  5DMZ A;  1RSD A;  2PN0 A;  1RRI A;  2KR1 A;  4UQF A;  3S19 A;  1RRY A;  1EL6 A;  2LO0 A;  4QPM A;  1NBU A;  4DU6 A;  2DHN A;  1FBX A;  1WM9 A;  3RZP A;  1NBU C;  2NM3 A;  4JA3 A;  1NBU B;  4GHM A;  1N3T A;  1FB1 A;  4F8B A;  3UXV A;  1WUQ A;  1IS8 A;  3VEJ A;  4DRA E;  1RSI A;  1RS4 A;  3V9O A;  1TFE A;  2LNZ A;  3R2E A;  1DHN A;  1U68 A;  1RS2 A;  4AEY A;  1WUR A;  4E44 B;  1RRW A;  2O90 A;  2CG8 A;  1GTP A;  4NE6 B;  1SQL A;  5F3M A;  1WPL A;  4NE3 B;  1B9L A;  3O1K A;  1AIP C;  3UXJ A;  4E45 B;  4IQI A;  3RJ4 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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1GTPA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations