1LB4A

Traf6 apo structure
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
159
structure length
155
Chain Sequence
QCNGIYIWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTAQRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPELLAFQRPTIKGFGYVTFMHLEALRQRTFIKDDTLLVRCEVSTRFDLE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Distinct molecular mechanism for initiating TRAF6 signalling.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords TNF receptor-associated factor 6
total genus 27
structure length 155
sequence length 159
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2002-04-02
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.210.10 Mainly Beta Sandwich Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A 1lb4A00
3HQHA 5H9MA 1YY6A 1FLLA 4GWMA 1D0AA 2GKWA 1QSCA 2XXNA 1CA4A 2F1ZA 1RF3A 4GHUA 2F1XA 2F1WA 1LB4A 2A25A 3HQMA 2CR2A 3IVBA 2FOPA 3IVQA 3IVVA 4I7DA 4KG9A 3HSVA 1FLKA 1KZZA 3HQIA 4I7BA 1ZMSA 3MQRA 4JJQA 5E1TA 3ZJBA 1LB5A 1LB6A 4YSIA 4C9ZA 1CZYA 1YZEA 2FOOA 4CA1A 4Z8MA 4GJHA 1D0JA 2AN6A 4I7CA 4K8UA 4X3GA 1K2FA 4M4EA 1D00A 1F3VB 4GWNA 1CA9A 4O1VA 2F1YA 3MQSC 1L0AA 1CZZA 3HU6A 1D01A 3HQLA 2FOJA
chains in the Genus database with same CATH superfamily
3HQHA 5H9MA 1YY6A 1FLLA 4GWMA 1D0AA 2GKWA 1QSCA 2XXNA 1CA4A 2F1ZA 1RF3A 4GHUA 2F1XA 2F1WA 1LB4A 2A25A 3HQMA 2CR2A 3IVBA 2FOPA 3IVQA 3IVVA 4I7DA 4KG9A 3HSVA 1FLKA 1KZZA 3HQIA 4I7BA 1ZMSA 3MQRA 4JJQA 5E1TA 3ZJBA 1LB5A 1LB6A 4YSIA 4C9ZA 1CZYA 1YZEA 2FOOA 4CA1A 4Z8MA 4GJHA 1D0JA 2AN6A 4I7CA 4K8UA 4X3GA 1K2FA 4M4EA 1D00A 1F3VB 4GWNA 1CA9A 4O1VA 2F1YA 3MQSC 1L0AA 1CZZA 3HU6A 1D01A 3HQLA 2FOJA
chains in the Genus database with same CATH topology
3HQHA 5H9MA 1YY6A 1FLLA 4GWMA 1D0AA 2GKWA 1QSCA 2XXNA 1CA4A 2F1ZA 1RF3A 4GHUA 2F1XA 2F1WA 1LB4A 2A25A 3HQMA 2CR2A 3IVBA 2FOPA 3IVQA 3IVVA 4I7DA 4KG9A 3HSVA 1FLKA 1KZZA 3HQIA 4I7BA 1ZMSA 3MQRA 4JJQA 5E1TA 3ZJBA 1LB5A 1LB6A 4YSIA 4C9ZA 1CZYA 1YZEA 2FOOA 4CA1A 4Z8MA 4GJHA 1D0JA 2AN6A 4I7CA 4K8UA 4X3GA 1K2FA 4M4EA 1D00A 1F3VB 4GWNA 1CA9A 4O1VA 2F1YA 3MQSC 1L0AA 1CZZA 3HU6A 1D01A 3HQLA 2FOJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HQH A;  5H9M A;  1YY6 A;  1FLL A;  4GWM A;  1D0A A;  2GKW A;  1QSC A;  2XXN A;  1CA4 A;  2F1Z A;  1RF3 A;  4GHU A;  2F1X A;  2F1W A;  1LB4 A;  2A25 A;  3HQM A;  2CR2 A;  3IVB A;  2FOP A;  3IVQ A;  3IVV A;  4I7D A;  4KG9 A;  3HSV A;  1FLK A;  1KZZ A;  3HQI A;  4I7B A;  1ZMS A;  3MQR A;  4JJQ A;  5E1T A;  3ZJB A;  1LB5 A;  1LB6 A;  4YSI A;  4C9Z A;  1CZY A;  1YZE A;  2FOO A;  4CA1 A;  4Z8M A;  4GJH A;  1D0J A;  2AN6 A;  4I7C A;  4K8U A;  4X3G A;  1K2F A;  4M4E A;  1D00 A;  1F3V B;  4GWN A;  1CA9 A;  4O1V A;  2F1Y A;  3MQS C;  1L0A A;  1CZZ A;  3HU6 A;  1D01 A;  3HQL A;  2FOJ A; 
#chains in the Genus database with same CATH topology
 3HQH A;  5H9M A;  1YY6 A;  1FLL A;  4GWM A;  1D0A A;  2GKW A;  1QSC A;  2XXN A;  1CA4 A;  2F1Z A;  1RF3 A;  4GHU A;  2F1X A;  2F1W A;  1LB4 A;  2A25 A;  3HQM A;  2CR2 A;  3IVB A;  2FOP A;  3IVQ A;  3IVV A;  4I7D A;  4KG9 A;  3HSV A;  1FLK A;  1KZZ A;  3HQI A;  4I7B A;  1ZMS A;  3MQR A;  4JJQ A;  5E1T A;  3ZJB A;  1LB5 A;  1LB6 A;  4YSI A;  4C9Z A;  1CZY A;  1YZE A;  2FOO A;  4CA1 A;  4Z8M A;  4GJH A;  1D0J A;  2AN6 A;  4I7C A;  4K8U A;  4X3G A;  1K2F A;  4M4E A;  1D00 A;  1F3V B;  4GWN A;  1CA9 A;  4O1V A;  2F1Y A;  3MQS C;  1L0A A;  1CZZ A;  3HU6 A;  1D01 A;  3HQL A;  2FOJ A; 
#chains in the Genus database with same CATH homology
 3HQH A;  5H9M A;  1YY6 A;  1FLL A;  4GWM A;  1D0A A;  2GKW A;  1QSC A;  2XXN A;  1CA4 A;  2F1Z A;  1RF3 A;  4GHU A;  2F1X A;  2F1W A;  1LB4 A;  2A25 A;  3HQM A;  2CR2 A;  3IVB A;  2FOP A;  3IVQ A;  3IVV A;  4I7D A;  4KG9 A;  3HSV A;  1FLK A;  1KZZ A;  3HQI A;  4I7B A;  1ZMS A;  3MQR A;  4JJQ A;  5E1T A;  3ZJB A;  1LB5 A;  1LB6 A;  4YSI A;  4C9Z A;  1CZY A;  1YZE A;  2FOO A;  4CA1 A;  4Z8M A;  4GJH A;  1D0J A;  2AN6 A;  4I7C A;  4K8U A;  4X3G A;  1K2F A;  4M4E A;  1D00 A;  1F3V B;  4GWN A;  1CA9 A;  4O1V A;  2F1Y A;  3MQS C;  1L0A A;  1CZZ A;  3HU6 A;  1D01 A;  3HQL A;  2FOJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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