1LB4A

Traf6 apo structure
Total Genus 27

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
159
structure length
155
Chain Sequence
QCNGIYIWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTAQRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPELLAFQRPTIKGFGYVTFMHLEALRQRTFIKDDTLLVRCEVSTRFDLE
2040608010012014014012010080604020
0510152025Genus Matrix

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
molecule tags Signaling protein
source organism Homo sapiens
publication title Distinct molecular mechanism for initiating TRAF6 signalling.
pubmed doi rcsb
molecule keywords TNF receptor-associated factor 6
total genus 27
structure length 155
sequence length 159
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2002-04-02
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.210.10 Mainly Beta Sandwich Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A 1lb4A00
4K8UA 4YSIA 4I7DA 1D00A 1D0JA 1CZZA 4JJQA 3ZJBA 4C9ZA 2FOOA 3HQMA 4GHUA 4O1VA 1LB4A 1K2FA 3MQSC 2A25A 1YY6A 2CR2A 1CZYA 3MQRA 1ZMSA 3HQIA 5E1TA 1FLKA 3HU6A 1YZEA 2F1YA 2F1ZA 3IVQA 1LB5A 1FLLA 4GWNA 3HQHA 1CA4A 3HQLA 1F3VB 1L0AA 1CA9A 2XXNA 1D0AA 4GWMA 1QSCA 3HSVA 4I7CA 3IVBA 4Z8MA 1RF3A 4X3GA 4CA1A 4M4EA 4GJHA 1KZZA 2AN6A 1D01A 4KG9A 2FOPA 5H9MA 3IVVA 4I7BA 2F1XA 1LB6A 2FOJA 2GKWA 2F1WA
chains in the Genus database with same CATH superfamily
4K8UA 4YSIA 4I7DA 1D00A 1D0JA 1CZZA 4JJQA 3ZJBA 4C9ZA 2FOOA 3HQMA 4GHUA 4O1VA 1LB4A 1K2FA 3MQSC 2A25A 1YY6A 2CR2A 1CZYA 3MQRA 1ZMSA 3HQIA 5E1TA 1FLKA 3HU6A 1YZEA 2F1YA 2F1ZA 3IVQA 1LB5A 1FLLA 4GWNA 3HQHA 1CA4A 3HQLA 1F3VB 1L0AA 1CA9A 2XXNA 1D0AA 4GWMA 1QSCA 3HSVA 4I7CA 3IVBA 4Z8MA 1RF3A 4X3GA 4CA1A 4M4EA 4GJHA 1KZZA 2AN6A 1D01A 4KG9A 2FOPA 5H9MA 3IVVA 4I7BA 2F1XA 1LB6A 2FOJA 2GKWA 2F1WA
chains in the Genus database with same CATH topology
4K8UA 4YSIA 4I7DA 1D00A 1D0JA 1CZZA 4JJQA 3ZJBA 4C9ZA 2FOOA 3HQMA 4GHUA 4O1VA 1LB4A 1K2FA 3MQSC 2A25A 1YY6A 2CR2A 1CZYA 3MQRA 1ZMSA 3HQIA 5E1TA 1FLKA 3HU6A 1YZEA 2F1YA 2F1ZA 3IVQA 1LB5A 1FLLA 4GWNA 3HQHA 1CA4A 3HQLA 1F3VB 1L0AA 1CA9A 2XXNA 1D0AA 4GWMA 1QSCA 3HSVA 4I7CA 3IVBA 4Z8MA 1RF3A 4X3GA 4CA1A 4M4EA 4GJHA 1KZZA 2AN6A 1D01A 4KG9A 2FOPA 5H9MA 3IVVA 4I7BA 2F1XA 1LB6A 2FOJA 2GKWA 2F1WA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 4K8U A;  4YSI A;  4I7D A;  1D00 A;  1D0J A;  1CZZ A;  4JJQ A;  3ZJB A;  4C9Z A;  2FOO A;  3HQM A;  4GHU A;  4O1V A;  1LB4 A;  1K2F A;  3MQS C;  2A25 A;  1YY6 A;  2CR2 A;  1CZY A;  3MQR A;  1ZMS A;  3HQI A;  5E1T A;  1FLK A;  3HU6 A;  1YZE A;  2F1Y A;  2F1Z A;  3IVQ A;  1LB5 A;  1FLL A;  4GWN A;  3HQH A;  1CA4 A;  3HQL A;  1F3V B;  1L0A A;  1CA9 A;  2XXN A;  1D0A A;  4GWM A;  1QSC A;  3HSV A;  4I7C A;  3IVB A;  4Z8M A;  1RF3 A;  4X3G A;  4CA1 A;  4M4E A;  4GJH A;  1KZZ A;  2AN6 A;  1D01 A;  4KG9 A;  2FOP A;  5H9M A;  3IVV A;  4I7B A;  2F1X A;  1LB6 A;  2FOJ A;  2GKW A;  2F1W A; 
#chains in the Genus database with same CATH topology
 4K8U A;  4YSI A;  4I7D A;  1D00 A;  1D0J A;  1CZZ A;  4JJQ A;  3ZJB A;  4C9Z A;  2FOO A;  3HQM A;  4GHU A;  4O1V A;  1LB4 A;  1K2F A;  3MQS C;  2A25 A;  1YY6 A;  2CR2 A;  1CZY A;  3MQR A;  1ZMS A;  3HQI A;  5E1T A;  1FLK A;  3HU6 A;  1YZE A;  2F1Y A;  2F1Z A;  3IVQ A;  1LB5 A;  1FLL A;  4GWN A;  3HQH A;  1CA4 A;  3HQL A;  1F3V B;  1L0A A;  1CA9 A;  2XXN A;  1D0A A;  4GWM A;  1QSC A;  3HSV A;  4I7C A;  3IVB A;  4Z8M A;  1RF3 A;  4X3G A;  4CA1 A;  4M4E A;  4GJH A;  1KZZ A;  2AN6 A;  1D01 A;  4KG9 A;  2FOP A;  5H9M A;  3IVV A;  4I7B A;  2F1X A;  1LB6 A;  2FOJ A;  2GKW A;  2F1W A; 
#chains in the Genus database with same CATH homology
 4K8U A;  4YSI A;  4I7D A;  1D00 A;  1D0J A;  1CZZ A;  4JJQ A;  3ZJB A;  4C9Z A;  2FOO A;  3HQM A;  4GHU A;  4O1V A;  1LB4 A;  1K2F A;  3MQS C;  2A25 A;  1YY6 A;  2CR2 A;  1CZY A;  3MQR A;  1ZMS A;  3HQI A;  5E1T A;  1FLK A;  3HU6 A;  1YZE A;  2F1Y A;  2F1Z A;  3IVQ A;  1LB5 A;  1FLL A;  4GWN A;  3HQH A;  1CA4 A;  3HQL A;  1F3V B;  1L0A A;  1CA9 A;  2XXN A;  1D0A A;  4GWM A;  1QSC A;  3HSV A;  4I7C A;  3IVB A;  4Z8M A;  1RF3 A;  4X3G A;  4CA1 A;  4M4E A;  4GJH A;  1KZZ A;  2AN6 A;  1D01 A;  4KG9 A;  2FOP A;  5H9M A;  3IVV A;  4I7B A;  2F1X A;  1LB6 A;  2FOJ A;  2GKW A;  2F1W A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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