1PQ0A

Crystal structure of mouse bcl-xl
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
195
structure length
144
Chain Sequence
SQSNRELVVDFLSYKLSQKGYSWSQFSDIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLYG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structure of a Bcl-xl/Bim fragment complex: Implications for Bim function
pubmed doi rcsb
molecule tags Apoptosis
source organism Mus musculus
molecule keywords Apoptosis regulator Bcl-X
total genus 57
structure length 144
sequence length 195
ec nomenclature
pdb deposition date 2003-06-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00452 Bcl-2 Apoptosis regulator proteins, Bcl-2 family
A PF02180 BH4 Bcl-2 homology region 4
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.437.10 Mainly Alpha Orthogonal Bundle Apoptosis Regulator Bcl-x Blc2-like 1pq0A00
2BIDA 4ZBFA 2NLAA 2O2MA 4K5BC 1OHUA 2VOGA 1MK3A 3IHCA 4BD7A 3IIGA 2O2NA 2O2FA 1BXLA 5FDOA 4ZBIA 1R2EA 2KUAA 2PQKA 1G5MA 1Q59A 2VOFA 3ILCA 1O0LA 1AF3A 5KTGA 4ZEQA 2KBWA 2MHSA 3KZ0A 3QBRA 4ZIEA 5IF4A 2VM6A 4ZIFA 5C6HA 1DDBA 3MQPA 1YSGA 3BL2A 2A5YA 3IHEA 5KU9A 4ZIGA 2MEJA 3IHDA 1TY4A 2WH6A 2W3LA 2ME8A 2XA0A 2O22A 4QNQA 1PQ1A 1YSIA 4OQ6A 4BDUA 3KJ1A 4BPJA 1F16A 4U2VA 2LR1A 2JM6B 1K3KA 4WMRA 2IMSA 4BD2A 4BPIA 4OQ5A 2K7WA 1R2DA 4YJ4A 4S0PA 3IIHA 1YSNA 4U2UA 4S0OA 1R2HA 2XPXA 4MI8A 4B4SA 4ZIHA 2M5BA 3D7VA 3WIYA 4HW2A 3PK1A 5IEZA 2YV6A 3KJ2A 1R2GA 1MAZA 5FC4A 5C3FA 3WIXA 2B48A 5FMIA 4HW3A 2ABOA 1R2IA 2NL9A 2VOIA 3CVAX 2ROCA 4QVXA 3DVUA 2O21A 3MK8A 1PQ0A 3KJ0A 1YSWA 2JCNA 4BD6A 4BD8A 1LXLA 4OYDA 2BZWA 2VOHA 4HW4A 2RODA 5FDRA 1G5JA 1ZY3A 3I1HA 4G35A 2IMTA 5JSBA 4ZIIA 4YK9A 2V6QA 1WSXA 1GJHA 3IO9A
chains in the Genus database with same CATH superfamily
2BIDA 4ZBFA 2NLAA 2O2MA 2VVYA 1OHUA 4K5BC 2VOGA 1MK3A 2I39A 3IHCA 4BD7A 3IIGA 2O2NA 2O2FA 1BXLA 4UF1A 5FDOA 4ZBIA 1R2EA 2KUAA 2VTYA 4LQKA 2VVWA 2PQKA 1G5MA 1Q59A 2VOFA 3ILCA 1O0LA 2UXEA 1AF3A 5KTGA 4ZEQA 2KBWA 2MHSA 3KZ0A 3QBRA 4ZIEA 5IF4A 2VM6A 4ZIFA 5C6HA 4M0SA 4UF2A 1DDBA 3MQPA 1YSGA 3BL2A 2A5YA 3IHEA 5KU9A 4ZIGA 2MEJA 3IHDA 1TY4A 2WH6A 2W3LA 2ME8A 2XA0A 2O22A 4QNQA 1PQ1A 1YSIA 4OQ6A 4BDUA 3KJ1A 4BPJA 1F16A 4U2VA 2LR1A 2JM6B 1K3KA 2O42A 4WMRA 4UF3A 2IMSA 4BD2A 4BPIA 4OQ5A 2K7WA 1R2DA 4YJ4A 4S0PA 3IIHA 1YSNA 4U2UA 4S0OA 4D2LA 3JRVA 1R2HA 2XPXA 4D2MA 4MI8A 4B4SA 4ZIHA 2M5BA 3D7VA 3WIYA 4HW2A 3PK1A 5IEZA 2YV6A 3KJ2A 1R2GA 1MAZA 5FC4A 5C3FA 2K36A 3WIXA 2B48A 5FMIA 2JBYA 4HW3A 2ABOA 1R2IA 2NL9A 2VOIA 4BBBA 3CVAX 2ROCA 4QVXA 3DVUA 2O21A 3MK8A 1PQ0A 3KJ0A 4BBDA 1YSWA 2JCNA 4BD6A 2VVXA 1LXLA 4BD8A 4OYDA 2JBXA 2BZWA 2VOHA 4HW4A 2RODA 5FDRA 1G5JA 1ZY3A 3I1HA 4BBCA 4G35A 2IMTA 5JSBA 4ZIIA 4YK9A 2V6QA 1WSXA 1GJHA 3IO9A
chains in the Genus database with same CATH topology
2BIDA 4ZBFA 2NLAA 2O2MA 4K5BC 1OHUA 2VOGA 1MK3A 3IHCA 4BD7A 3IIGA 2O2NA 2O2FA 1BXLA 5FDOA 4ZBIA 1R2EA 2KUAA 2PQKA 1G5MA 1Q59A 2VOFA 3ILCA 1O0LA 1AF3A 5KTGA 4ZEQA 2KBWA 2MHSA 3KZ0A 3QBRA 4ZIEA 5IF4A 2VM6A 4ZIFA 5C6HA 1DDBA 3MQPA 1YSGA 3BL2A 2A5YA 3IHEA 5KU9A 4ZIGA 2MEJA 3IHDA 1TY4A 2WH6A 2W3LA 2ME8A 2XA0A 2O22A 4QNQA 1PQ1A 1YSIA 4OQ6A 4BDUA 3KJ1A 4BPJA 1F16A 4U2VA 2LR1A 2JM6B 1K3KA 4WMRA 2IMSA 4BD2A 4BPIA 4OQ5A 2K7WA 1R2DA 4YJ4A 4S0PA 3IIHA 1YSNA 4U2UA 4S0OA 1R2HA 2XPXA 4MI8A 4B4SA 4ZIHA 2M5BA 3D7VA 3WIYA 4HW2A 3PK1A 5IEZA 2YV6A 3KJ2A 1R2GA 1MAZA 5FC4A 5C3FA 3WIXA 2B48A 5FMIA 4HW3A 2ABOA 1R2IA 2NL9A 2VOIA 3CVAX 2ROCA 4QVXA 3DVUA 2O21A 3MK8A 1PQ0A 3KJ0A 1YSWA 2JCNA 4BD6A 4BD8A 1LXLA 4OYDA 2BZWA 2VOHA 4HW4A 2RODA 5FDRA 1G5JA 1ZY3A 3I1HA 4G35A 2IMTA 5JSBA 4ZIIA 4YK9A 2V6QA 1WSXA 1GJHA 3IO9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BID A;  4ZBF A;  2NLA A;  2O2M A;  4K5B C;  1OHU A;  2VOG A;  1MK3 A;  3IHC A;  4BD7 A;  3IIG A;  2O2N A;  2O2F A;  1BXL A;  5FDO A;  4ZBI A;  1R2E A;  2KUA A;  2PQK A;  1G5M A;  1Q59 A;  2VOF A;  3ILC A;  1O0L A;  1AF3 A;  5KTG A;  4ZEQ A;  2KBW A;  2MHS A;  3KZ0 A;  3QBR A;  4ZIE A;  5IF4 A;  2VM6 A;  4ZIF A;  5C6H A;  1DDB A;  3MQP A;  1YSG A;  3BL2 A;  2A5Y A;  3IHE A;  5KU9 A;  4ZIG A;  2MEJ A;  3IHD A;  1TY4 A;  2WH6 A;  2W3L A;  2ME8 A;  2XA0 A;  2O22 A;  4QNQ A;  1PQ1 A;  1YSI A;  4OQ6 A;  4BDU A;  3KJ1 A;  4BPJ A;  1F16 A;  4U2V A;  2LR1 A;  2JM6 B;  1K3K A;  4WMR A;  2IMS A;  4BD2 A;  4BPI A;  4OQ5 A;  2K7W A;  1R2D A;  4YJ4 A;  4S0P A;  3IIH A;  1YSN A;  4U2U A;  4S0O A;  1R2H A;  2XPX A;  4MI8 A;  4B4S A;  4ZIH A;  2M5B A;  3D7V A;  3WIY A;  4HW2 A;  3PK1 A;  5IEZ A;  2YV6 A;  3KJ2 A;  1R2G A;  1MAZ A;  5FC4 A;  5C3F A;  3WIX A;  2B48 A;  5FMI A;  4HW3 A;  2ABO A;  1R2I A;  2NL9 A;  2VOI A;  3CVA X;  2ROC A;  4QVX A;  3DVU A;  2O21 A;  3MK8 A;  1PQ0 A;  3KJ0 A;  1YSW A;  2JCN A;  4BD6 A;  4BD8 A;  1LXL A;  4OYD A;  2BZW A;  2VOH A;  4HW4 A;  2ROD A;  5FDR A;  1G5J A;  1ZY3 A;  3I1H A;  4G35 A;  2IMT A;  5JSB A;  4ZII A;  4YK9 A;  2V6Q A;  1WSX A;  1GJH A;  3IO9 A; 
#chains in the Genus database with same CATH topology
 2BID A;  4ZBF A;  2NLA A;  2O2M A;  2VVY A;  1OHU A;  4K5B C;  2VOG A;  1MK3 A;  2I39 A;  3IHC A;  4BD7 A;  3IIG A;  2O2N A;  2O2F A;  1BXL A;  4UF1 A;  5FDO A;  4ZBI A;  1R2E A;  2KUA A;  2VTY A;  4LQK A;  2VVW A;  2PQK A;  1G5M A;  1Q59 A;  2VOF A;  3ILC A;  1O0L A;  2UXE A;  1AF3 A;  5KTG A;  4ZEQ A;  2KBW A;  2MHS A;  3KZ0 A;  3QBR A;  4ZIE A;  5IF4 A;  2VM6 A;  4ZIF A;  5C6H A;  4M0S A;  4UF2 A;  1DDB A;  3MQP A;  1YSG A;  3BL2 A;  2A5Y A;  3IHE A;  5KU9 A;  4ZIG A;  2MEJ A;  3IHD A;  1TY4 A;  2WH6 A;  2W3L A;  2ME8 A;  2XA0 A;  2O22 A;  4QNQ A;  1PQ1 A;  1YSI A;  4OQ6 A;  4BDU A;  3KJ1 A;  4BPJ A;  1F16 A;  4U2V A;  2LR1 A;  2JM6 B;  1K3K A;  2O42 A;  4WMR A;  4UF3 A;  2IMS A;  4BD2 A;  4BPI A;  4OQ5 A;  2K7W A;  1R2D A;  4YJ4 A;  4S0P A;  3IIH A;  1YSN A;  4U2U A;  4S0O A;  4D2L A;  3JRV A;  1R2H A;  2XPX A;  4D2M A;  4MI8 A;  4B4S A;  4ZIH A;  2M5B A;  3D7V A;  3WIY A;  4HW2 A;  3PK1 A;  5IEZ A;  2YV6 A;  3KJ2 A;  1R2G A;  1MAZ A;  5FC4 A;  5C3F A;  2K36 A;  3WIX A;  2B48 A;  5FMI A;  2JBY A;  4HW3 A;  2ABO A;  1R2I A;  2NL9 A;  2VOI A;  4BBB A;  3CVA X;  2ROC A;  4QVX A;  3DVU A;  2O21 A;  3MK8 A;  1PQ0 A;  3KJ0 A;  4BBD A;  1YSW A;  2JCN A;  4BD6 A;  2VVX A;  1LXL A;  4BD8 A;  4OYD A;  2JBX A;  2BZW A;  2VOH A;  4HW4 A;  2ROD A;  5FDR A;  1G5J A;  1ZY3 A;  3I1H A;  4BBC A;  4G35 A;  2IMT A;  5JSB A;  4ZII A;  4YK9 A;  2V6Q A;  1WSX A;  1GJH A;  3IO9 A; 
#chains in the Genus database with same CATH homology
 2BID A;  4ZBF A;  2NLA A;  2O2M A;  4K5B C;  1OHU A;  2VOG A;  1MK3 A;  3IHC A;  4BD7 A;  3IIG A;  2O2N A;  2O2F A;  1BXL A;  5FDO A;  4ZBI A;  1R2E A;  2KUA A;  2PQK A;  1G5M A;  1Q59 A;  2VOF A;  3ILC A;  1O0L A;  1AF3 A;  5KTG A;  4ZEQ A;  2KBW A;  2MHS A;  3KZ0 A;  3QBR A;  4ZIE A;  5IF4 A;  2VM6 A;  4ZIF A;  5C6H A;  1DDB A;  3MQP A;  1YSG A;  3BL2 A;  2A5Y A;  3IHE A;  5KU9 A;  4ZIG A;  2MEJ A;  3IHD A;  1TY4 A;  2WH6 A;  2W3L A;  2ME8 A;  2XA0 A;  2O22 A;  4QNQ A;  1PQ1 A;  1YSI A;  4OQ6 A;  4BDU A;  3KJ1 A;  4BPJ A;  1F16 A;  4U2V A;  2LR1 A;  2JM6 B;  1K3K A;  4WMR A;  2IMS A;  4BD2 A;  4BPI A;  4OQ5 A;  2K7W A;  1R2D A;  4YJ4 A;  4S0P A;  3IIH A;  1YSN A;  4U2U A;  4S0O A;  1R2H A;  2XPX A;  4MI8 A;  4B4S A;  4ZIH A;  2M5B A;  3D7V A;  3WIY A;  4HW2 A;  3PK1 A;  5IEZ A;  2YV6 A;  3KJ2 A;  1R2G A;  1MAZ A;  5FC4 A;  5C3F A;  3WIX A;  2B48 A;  5FMI A;  4HW3 A;  2ABO A;  1R2I A;  2NL9 A;  2VOI A;  3CVA X;  2ROC A;  4QVX A;  3DVU A;  2O21 A;  3MK8 A;  1PQ0 A;  3KJ0 A;  1YSW A;  2JCN A;  4BD6 A;  4BD8 A;  1LXL A;  4OYD A;  2BZW A;  2VOH A;  4HW4 A;  2ROD A;  5FDR A;  1G5J A;  1ZY3 A;  3I1H A;  4G35 A;  2IMT A;  5JSB A;  4ZII A;  4YK9 A;  2V6Q A;  1WSX A;  1GJH A;  3IO9 A; 
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similar chains in the pdb database (?% sequence similarity)

 
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