1QSCA

Crystal structure of the traf domain of traf2 in a complex with a peptide from the cd40 receptor
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
179
structure length
179
Chain Sequence
QLERSIGLKDLAMADLEQKVLEMEASTYDGVFIWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQNNREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDLTGL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystallographic analysis of CD40 recognition and signaling by human TRAF2.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords TNF RECEPTOR ASSOCIATED FACTOR 2
total genus 36
structure length 179
sequence length 179
chains with identical sequence B, C
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 1999-06-20
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.210.10 Mainly Beta Sandwich Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A 1qscA00
1FLKA 2CR2A 4GJHA 1ZMSA 4O1VA 4KG9A 1CZYA 1KZZA 2F1ZA 4I7BA 3IVVA 5H9MA 5E1TA 4Z8MA 3HQIA 4M4EA 1D01A 2F1YA 3HQHA 1LB4A 2FOPA 1D0JA 4X3GA 1CZZA 4I7CA 2GKWA 3ZJBA 2XXNA 2FOOA 2A25A 2F1XA 1CA9A 4GWNA 4K8UA 1F3VB 2AN6A 3HU6A 4YSIA 1YY6A 1D0AA 3MQSC 1CA4A 4GWMA 4CA1A 1LB6A 4C9ZA 3IVQA 3HQLA 1L0AA 3HQMA 1D00A 2F1WA 3MQRA 4JJQA 1K2FA 2FOJA 1RF3A 4GHUA 3IVBA 1YZEA 1LB5A 4I7DA 1QSCA 1FLLA 3HSVA
chains in the Genus database with same CATH superfamily
1FLKA 2CR2A 4GJHA 1ZMSA 4O1VA 4KG9A 1CZYA 1KZZA 2F1ZA 4I7BA 3IVVA 5H9MA 5E1TA 4Z8MA 3HQIA 4M4EA 1D01A 2F1YA 3HQHA 1LB4A 2FOPA 1D0JA 4X3GA 1CZZA 4I7CA 2GKWA 3ZJBA 2XXNA 2FOOA 2A25A 2F1XA 1CA9A 4GWNA 4K8UA 1F3VB 2AN6A 3HU6A 4YSIA 1YY6A 1D0AA 3MQSC 1CA4A 4GWMA 4CA1A 1LB6A 4C9ZA 3IVQA 3HQLA 1L0AA 3HQMA 1D00A 2F1WA 3MQRA 4JJQA 1K2FA 2FOJA 1RF3A 4GHUA 3IVBA 1YZEA 1LB5A 4I7DA 1QSCA 1FLLA 3HSVA
chains in the Genus database with same CATH topology
1FLKA 2CR2A 4GJHA 1ZMSA 4O1VA 4KG9A 1CZYA 1KZZA 2F1ZA 4I7BA 3IVVA 5H9MA 5E1TA 4Z8MA 3HQIA 4M4EA 1D01A 2F1YA 3HQHA 1LB4A 2FOPA 1D0JA 4X3GA 1CZZA 4I7CA 2GKWA 3ZJBA 2XXNA 2FOOA 2A25A 2F1XA 1CA9A 4GWNA 4K8UA 1F3VB 2AN6A 3HU6A 4YSIA 1YY6A 1D0AA 3MQSC 1CA4A 4GWMA 4CA1A 1LB6A 4C9ZA 3IVQA 3HQLA 1L0AA 3HQMA 1D00A 2F1WA 3MQRA 4JJQA 1K2FA 2FOJA 1RF3A 4GHUA 3IVBA 1YZEA 1LB5A 4I7DA 1QSCA 1FLLA 3HSVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FLK A;  2CR2 A;  4GJH A;  1ZMS A;  4O1V A;  4KG9 A;  1CZY A;  1KZZ A;  2F1Z A;  4I7B A;  3IVV A;  5H9M A;  5E1T A;  4Z8M A;  3HQI A;  4M4E A;  1D01 A;  2F1Y A;  3HQH A;  1LB4 A;  2FOP A;  1D0J A;  4X3G A;  1CZZ A;  4I7C A;  2GKW A;  3ZJB A;  2XXN A;  2FOO A;  2A25 A;  2F1X A;  1CA9 A;  4GWN A;  4K8U A;  1F3V B;  2AN6 A;  3HU6 A;  4YSI A;  1YY6 A;  1D0A A;  3MQS C;  1CA4 A;  4GWM A;  4CA1 A;  1LB6 A;  4C9Z A;  3IVQ A;  3HQL A;  1L0A A;  3HQM A;  1D00 A;  2F1W A;  3MQR A;  4JJQ A;  1K2F A;  2FOJ A;  1RF3 A;  4GHU A;  3IVB A;  1YZE A;  1LB5 A;  4I7D A;  1QSC A;  1FLL A;  3HSV A; 
#chains in the Genus database with same CATH topology
 1FLK A;  2CR2 A;  4GJH A;  1ZMS A;  4O1V A;  4KG9 A;  1CZY A;  1KZZ A;  2F1Z A;  4I7B A;  3IVV A;  5H9M A;  5E1T A;  4Z8M A;  3HQI A;  4M4E A;  1D01 A;  2F1Y A;  3HQH A;  1LB4 A;  2FOP A;  1D0J A;  4X3G A;  1CZZ A;  4I7C A;  2GKW A;  3ZJB A;  2XXN A;  2FOO A;  2A25 A;  2F1X A;  1CA9 A;  4GWN A;  4K8U A;  1F3V B;  2AN6 A;  3HU6 A;  4YSI A;  1YY6 A;  1D0A A;  3MQS C;  1CA4 A;  4GWM A;  4CA1 A;  1LB6 A;  4C9Z A;  3IVQ A;  3HQL A;  1L0A A;  3HQM A;  1D00 A;  2F1W A;  3MQR A;  4JJQ A;  1K2F A;  2FOJ A;  1RF3 A;  4GHU A;  3IVB A;  1YZE A;  1LB5 A;  4I7D A;  1QSC A;  1FLL A;  3HSV A; 
#chains in the Genus database with same CATH homology
 1FLK A;  2CR2 A;  4GJH A;  1ZMS A;  4O1V A;  4KG9 A;  1CZY A;  1KZZ A;  2F1Z A;  4I7B A;  3IVV A;  5H9M A;  5E1T A;  4Z8M A;  3HQI A;  4M4E A;  1D01 A;  2F1Y A;  3HQH A;  1LB4 A;  2FOP A;  1D0J A;  4X3G A;  1CZZ A;  4I7C A;  2GKW A;  3ZJB A;  2XXN A;  2FOO A;  2A25 A;  2F1X A;  1CA9 A;  4GWN A;  4K8U A;  1F3V B;  2AN6 A;  3HU6 A;  4YSI A;  1YY6 A;  1D0A A;  3MQS C;  1CA4 A;  4GWM A;  4CA1 A;  1LB6 A;  4C9Z A;  3IVQ A;  3HQL A;  1L0A A;  3HQM A;  1D00 A;  2F1W A;  3MQR A;  4JJQ A;  1K2F A;  2FOJ A;  1RF3 A;  4GHU A;  3IVB A;  1YZE A;  1LB5 A;  4I7D A;  1QSC A;  1FLL A;  3HSV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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