1QSCA

Crystal structure of the traf domain of traf2 in a complex with a peptide from the cd40 receptor
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
179
structure length
179
Chain Sequence
QLERSIGLKDLAMADLEQKVLEMEASTYDGVFIWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQNNREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDLTGL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
molecule tags Signaling protein
source organism Homo sapiens
publication title Crystallographic analysis of CD40 recognition and signaling by human TRAF2.
pubmed doi rcsb
molecule keywords TNF RECEPTOR ASSOCIATED FACTOR 2
total genus 36
structure length 179
sequence length 179
chains with identical sequence B, C
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 1999-06-20
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.210.10 Mainly Beta Sandwich Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A 1qscA00
2F1XA 2FOPA 4I7CA 4I7DA 4JJQA 4O1VA 4CA1A 2XXNA 1CA4A 3IVQA 2F1WA 2GKWA 1KZZA 4Z8MA 3HU6A 3HQHA 4GJHA 1FLKA 2CR2A 1D0JA 1QSCA 1D01A 1LB4A 3MQRA 1L0AA 4K8UA 5E1TA 2AN6A 1CZYA 2F1ZA 4GWMA 4M4EA 1ZMSA 4C9ZA 1LB6A 1YY6A 3ZJBA 1F3VB 2F1YA 1CZZA 3HQIA 4I7BA 3MQSC 1D00A 2A25A 1RF3A 4X3GA 4YSIA 1CA9A 1FLLA 1LB5A 1K2FA 3IVBA 2FOJA 3HSVA 2FOOA 3HQLA 4GWNA 5H9MA 3IVVA 1YZEA 3HQMA 1D0AA 4GHUA 4KG9A
chains in the Genus database with same CATH superfamily
2F1XA 2FOPA 4I7CA 4I7DA 4JJQA 4O1VA 4CA1A 2XXNA 1CA4A 3IVQA 2F1WA 2GKWA 1KZZA 4Z8MA 3HU6A 3HQHA 4GJHA 1FLKA 2CR2A 1D0JA 1QSCA 1D01A 1LB4A 3MQRA 1L0AA 4K8UA 5E1TA 2AN6A 1CZYA 2F1ZA 4GWMA 4M4EA 1ZMSA 4C9ZA 1LB6A 1YY6A 3ZJBA 1F3VB 2F1YA 1CZZA 3HQIA 4I7BA 3MQSC 1D00A 2A25A 1RF3A 4X3GA 4YSIA 1CA9A 1FLLA 1LB5A 1K2FA 3IVBA 2FOJA 3HSVA 2FOOA 3HQLA 4GWNA 5H9MA 3IVVA 1YZEA 3HQMA 1D0AA 4GHUA 4KG9A
chains in the Genus database with same CATH topology
2F1XA 2FOPA 4I7CA 4I7DA 4JJQA 4O1VA 4CA1A 2XXNA 1CA4A 3IVQA 2F1WA 2GKWA 1KZZA 4Z8MA 3HU6A 3HQHA 4GJHA 1FLKA 2CR2A 1D0JA 1QSCA 1D01A 1LB4A 3MQRA 1L0AA 4K8UA 5E1TA 2AN6A 1CZYA 2F1ZA 4GWMA 4M4EA 1ZMSA 4C9ZA 1LB6A 1YY6A 3ZJBA 1F3VB 2F1YA 1CZZA 3HQIA 4I7BA 3MQSC 1D00A 2A25A 1RF3A 4X3GA 4YSIA 1CA9A 1FLLA 1LB5A 1K2FA 3IVBA 2FOJA 3HSVA 2FOOA 3HQLA 4GWNA 5H9MA 3IVVA 1YZEA 3HQMA 1D0AA 4GHUA 4KG9A
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2F1X A;  2FOP A;  4I7C A;  4I7D A;  4JJQ A;  4O1V A;  4CA1 A;  2XXN A;  1CA4 A;  3IVQ A;  2F1W A;  2GKW A;  1KZZ A;  4Z8M A;  3HU6 A;  3HQH A;  4GJH A;  1FLK A;  2CR2 A;  1D0J A;  1QSC A;  1D01 A;  1LB4 A;  3MQR A;  1L0A A;  4K8U A;  5E1T A;  2AN6 A;  1CZY A;  2F1Z A;  4GWM A;  4M4E A;  1ZMS A;  4C9Z A;  1LB6 A;  1YY6 A;  3ZJB A;  1F3V B;  2F1Y A;  1CZZ A;  3HQI A;  4I7B A;  3MQS C;  1D00 A;  2A25 A;  1RF3 A;  4X3G A;  4YSI A;  1CA9 A;  1FLL A;  1LB5 A;  1K2F A;  3IVB A;  2FOJ A;  3HSV A;  2FOO A;  3HQL A;  4GWN A;  5H9M A;  3IVV A;  1YZE A;  3HQM A;  1D0A A;  4GHU A;  4KG9 A; 
#chains in the Genus database with same CATH topology
 2F1X A;  2FOP A;  4I7C A;  4I7D A;  4JJQ A;  4O1V A;  4CA1 A;  2XXN A;  1CA4 A;  3IVQ A;  2F1W A;  2GKW A;  1KZZ A;  4Z8M A;  3HU6 A;  3HQH A;  4GJH A;  1FLK A;  2CR2 A;  1D0J A;  1QSC A;  1D01 A;  1LB4 A;  3MQR A;  1L0A A;  4K8U A;  5E1T A;  2AN6 A;  1CZY A;  2F1Z A;  4GWM A;  4M4E A;  1ZMS A;  4C9Z A;  1LB6 A;  1YY6 A;  3ZJB A;  1F3V B;  2F1Y A;  1CZZ A;  3HQI A;  4I7B A;  3MQS C;  1D00 A;  2A25 A;  1RF3 A;  4X3G A;  4YSI A;  1CA9 A;  1FLL A;  1LB5 A;  1K2F A;  3IVB A;  2FOJ A;  3HSV A;  2FOO A;  3HQL A;  4GWN A;  5H9M A;  3IVV A;  1YZE A;  3HQM A;  1D0A A;  4GHU A;  4KG9 A; 
#chains in the Genus database with same CATH homology
 2F1X A;  2FOP A;  4I7C A;  4I7D A;  4JJQ A;  4O1V A;  4CA1 A;  2XXN A;  1CA4 A;  3IVQ A;  2F1W A;  2GKW A;  1KZZ A;  4Z8M A;  3HU6 A;  3HQH A;  4GJH A;  1FLK A;  2CR2 A;  1D0J A;  1QSC A;  1D01 A;  1LB4 A;  3MQR A;  1L0A A;  4K8U A;  5E1T A;  2AN6 A;  1CZY A;  2F1Z A;  4GWM A;  4M4E A;  1ZMS A;  4C9Z A;  1LB6 A;  1YY6 A;  3ZJB A;  1F3V B;  2F1Y A;  1CZZ A;  3HQI A;  4I7B A;  3MQS C;  1D00 A;  2A25 A;  1RF3 A;  4X3G A;  4YSI A;  1CA9 A;  1FLL A;  1LB5 A;  1K2F A;  3IVB A;  2FOJ A;  3HSV A;  2FOO A;  3HQL A;  4GWN A;  5H9M A;  3IVV A;  1YZE A;  3HQM A;  1D0A A;  4GHU A;  4KG9 A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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