1S0WC

1b lactamse/ b lactamase inhibitor
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
165
structure length
165
Chain Sequence
AGVMTGAKFTQIQFGMTRQQVLDIAGAENCETGGSFGDSIHCRGHAAGDYYAYATFGFTSAAADAKVDSKSQEKLLAPSAPTLTLAKFNQVTVGMTRAQVLATVGQGSCTTWSEYYPAYPSTAGVTLSLSCFDVDGYSSTGAYRGSAHLWFTDGVLQGKRQWDLV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The modular architecture of protein-protein binding interfaces.
pubmed doi rcsb
molecule keywords beta-lactamase TEM
molecule tags Hydrolase
source organism Escherichia coli
total genus 48
structure length 165
sequence length 165
chains with identical sequence D
ec nomenclature
pdb deposition date 2004-01-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF07467 BLIP Beta-lactamase inhibitor (BLIP)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1450.10 Alpha Beta 2-Layer Sandwich Beta-lactamase Inhibitory Protein; Chain:B, domain 1 Beta-lactamase Inhibitory Protein; Chain:B, domain 1 1s0wC02
3.30.1450.10 Alpha Beta 2-Layer Sandwich Beta-lactamase Inhibitory Protein; Chain:B, domain 1 Beta-lactamase Inhibitory Protein; Chain:B, domain 1 1s0wC01
2KXXA 5D0QE 5D0OE 3E2LC 5AYWE 5EKQE 4DM5A 3C7VB 2G2WB 3C4OB 1S0WC 2YH9A 3GMUB 3D4EA 1XXMC 2KM7A 3C4PB 2PXGA 2G2UB 3E2KC 1JTGB 2B5RC 3C7UB 3N4IB
chains in the Genus database with same CATH superfamily
2KXXA 5D0QE 5D0OE 3E2LC 5AYWE 4HSIA 5EKQE 4DM5A 3C7VB 2G2WB 3C4OB 1S0WC 3NWDA 2YH9A 3FVCA 3NW8A 3GMUB 3D4EA 3NWFA 1XXMC 2KM7A 3C4PB 4L1RA 2PXGA 3N4IB 2G2UB 3E2KC 2B5RC 3C7UB 3NWAA 2GUMA 1JTGB
chains in the Genus database with same CATH topology
2KXXA 5D0QE 5D0OE 3E2LC 5AYWE 4HSIA 5EKQE 4DM5A 3C7VB 2G2WB 3C4OB 1S0WC 3NWDA 2YH9A 3FVCA 3NW8A 3GMUB 3D4EA 3NWFA 1XXMC 2KM7A 3C4PB 4L1RA 2PXGA 3N4IB 2G2UB 3E2KC 2B5RC 3C7UB 3NWAA 2GUMA 1JTGB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KXX A;  5D0Q E;  5D0O E;  3E2L C;  5AYW E;  5EKQ E;  4DM5 A;  3C7V B;  2G2W B;  3C4O B;  1S0W C;  2YH9 A;  3GMU B;  3D4E A;  1XXM C;  2KM7 A;  3C4P B;  2PXG A;  2G2U B;  3E2K C;  1JTG B;  2B5R C;  3C7U B;  3N4I B; 
#chains in the Genus database with same CATH topology
 2KXX A;  5D0Q E;  5D0O E;  3E2L C;  5AYW E;  4HSI A;  5EKQ E;  4DM5 A;  3C7V B;  2G2W B;  3C4O B;  1S0W C;  3NWD A;  2YH9 A;  3FVC A;  3NW8 A;  3GMU B;  3D4E A;  3NWF A;  1XXM C;  2KM7 A;  3C4P B;  4L1R A;  2PXG A;  3N4I B;  2G2U B;  3E2K C;  2B5R C;  3C7U B;  3NWA A;  2GUM A;  1JTG B; 
#chains in the Genus database with same CATH homology
 2KXX A;  5D0Q E;  5D0O E;  3E2L C;  5AYW E;  4HSI A;  5EKQ E;  4DM5 A;  3C7V B;  2G2W B;  3C4O B;  1S0W C;  3NWD A;  2YH9 A;  3FVC A;  3NW8 A;  3GMU B;  3D4E A;  3NWF A;  1XXM C;  2KM7 A;  3C4P B;  4L1R A;  2PXG A;  3N4I B;  2G2U B;  3E2K C;  2B5R C;  3C7U B;  3NWA A;  2GUM A;  1JTG B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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