2B5RC

1b lactamase / b lactamase inhibitor
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
165
structure length
165
Chain Sequence
AGVMTGAKFTQIQFGMTRQQVLDIAGAENCETGGSFGDSIHCRGHAAGDYYAYATFGFTSAAADAKVDSKSQEKLLAPSAPTLTLAKFNQVTVGMTRAQVLATVGQGSCTTWSEYYPAYPSTAGVTLSLSCFDVDGYSSTGFYRGSAHLWFTDGVLQGKRQWDLV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Binding Hot Spots in the TEM1-BLIP Interface in Light of its Modular Architecture.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Escherichia coli
molecule keywords Beta-lactamase TEM
total genus 46
structure length 165
sequence length 165
chains with identical sequence D
ec nomenclature
pdb deposition date 2005-09-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF07467 BLIP Beta-lactamase inhibitor (BLIP)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1450.10 Alpha Beta 2-Layer Sandwich Beta-lactamase Inhibitory Protein; Chain:B, domain 1 Beta-lactamase Inhibitory Protein; Chain:B, domain 1 2b5rC01
3.30.1450.10 Alpha Beta 2-Layer Sandwich Beta-lactamase Inhibitory Protein; Chain:B, domain 1 Beta-lactamase Inhibitory Protein; Chain:B, domain 1 2b5rC02
3C7VB 3N4IB 2YH9A 4DM5A 1JTGB 3E2KC 5D0QE 2PXGA 2G2UB 3E2LC 1XXMC 3C4PB 5EKQE 2G2WB 3C4OB 2KM7A 5D0OE 5AYWE 1S0WC 3D4EA 2B5RC 2KXXA 3C7UB 3GMUB
chains in the Genus database with same CATH superfamily
3C7VB 3N4IB 2YH9A 4DM5A 4HSIA 1JTGB 3E2KC 5D0QE 2PXGA 2G2UB 3NW8A 3NWFA 3E2LC 3NWAA 1XXMC 3C4PB 5EKQE 3FVCA 2G2WB 3NWDA 2GUMA 3C4OB 2KM7A 5D0OE 5AYWE 1S0WC 4L1RA 3D4EA 2B5RC 2KXXA 3C7UB 3GMUB
chains in the Genus database with same CATH topology
3C7VB 3N4IB 2YH9A 4DM5A 4HSIA 1JTGB 3E2KC 5D0QE 2PXGA 2G2UB 3NW8A 3NWFA 3E2LC 3NWAA 1XXMC 3C4PB 5EKQE 3FVCA 2G2WB 3NWDA 2GUMA 3C4OB 2KM7A 5D0OE 5AYWE 1S0WC 4L1RA 3D4EA 2B5RC 2KXXA 3C7UB 3GMUB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3C7V B;  3N4I B;  2YH9 A;  4DM5 A;  1JTG B;  3E2K C;  5D0Q E;  2PXG A;  2G2U B;  3E2L C;  1XXM C;  3C4P B;  5EKQ E;  2G2W B;  3C4O B;  2KM7 A;  5D0O E;  5AYW E;  1S0W C;  3D4E A;  2B5R C;  2KXX A;  3C7U B;  3GMU B; 
#chains in the Genus database with same CATH topology
 3C7V B;  3N4I B;  2YH9 A;  4DM5 A;  4HSI A;  1JTG B;  3E2K C;  5D0Q E;  2PXG A;  2G2U B;  3NW8 A;  3NWF A;  3E2L C;  3NWA A;  1XXM C;  3C4P B;  5EKQ E;  3FVC A;  2G2W B;  3NWD A;  2GUM A;  3C4O B;  2KM7 A;  5D0O E;  5AYW E;  1S0W C;  4L1R A;  3D4E A;  2B5R C;  2KXX A;  3C7U B;  3GMU B; 
#chains in the Genus database with same CATH homology
 3C7V B;  3N4I B;  2YH9 A;  4DM5 A;  4HSI A;  1JTG B;  3E2K C;  5D0Q E;  2PXG A;  2G2U B;  3NW8 A;  3NWF A;  3E2L C;  3NWA A;  1XXM C;  3C4P B;  5EKQ E;  3FVC A;  2G2W B;  3NWD A;  2GUM A;  3C4O B;  2KM7 A;  5D0O E;  5AYW E;  1S0W C;  4L1R A;  3D4E A;  2B5R C;  2KXX A;  3C7U B;  3GMU B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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