1SJ7A

Crystal structure of talin rod 482-655
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
167
structure length
167
Chain Sequence
LTSAQQALTGTINSSMQAVQAAQATLDDFETLPPLGQDAASKAWRKNKMDESKHEIHSQVDAITAGTASVVNLTAGDPAETDYTAVGCAVTTISSNLTEMSRGVKLLAALLEDEGGNGRPLLQAAKGLAGAVSELLRSAQPASAEPRQNLLQAAGNVGQASGELLQQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle
pubmed doi rcsb
molecule tags Structural protein
source organism Mus musculus
molecule keywords Talin 1
total genus 70
structure length 167
sequence length 167
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2004-03-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09141 Talin_middle Talin, middle domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1420.10 Mainly Alpha Up-down Bundle A middle domain of Talin 1 Talin, central domain 1sj7A00
2L10A 1SJ7A 2KBBA 5FZTA 3AY5A 1SJ8A 2KVPA 2X0CA 4F7GB 3DYJA 3FYQA 2KGXA 4W8PA 2L7NA
chains in the Genus database with same CATH superfamily
5JDNA 2KBBA 3AY5A 1SJ8A 5JDGA 5JDFA 2L10A 3AT7A 3PF0A 5JDLA 5JDMA 5HXCA 3V5UA 4ONRA 5HWXA 4F7GB 2X0CA 3WSCA 3DYJA 2L7NA 3WURA 1SJ7A 5HXRA 2XQYA 2LQUA 5HWYA 4BGOA 3PHF1 5HXHA 2MTCA 3V5SA 4W8PA 3VJZA 5JDQA 5JDHA 5FZTA 3M1CA 5HXSA 5HXEA 2KVPA 5T1DA 4ECGA 3FYQA 2KGXA 5HYAA
chains in the Genus database with same CATH topology
2L10A 1SJ7A 2KBBA 5FZTA 3AY5A 1SJ8A 2KVPA 2X0CA 4F7GB 3DYJA 3FYQA 2KGXA 4W8PA 2L7NA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2L10 A;  1SJ7 A;  2KBB A;  5FZT A;  3AY5 A;  1SJ8 A;  2KVP A;  2X0C A;  4F7G B;  3DYJ A;  3FYQ A;  2KGX A;  4W8P A;  2L7N A; 
#chains in the Genus database with same CATH topology
 5JDN A;  2KBB A;  3AY5 A;  1SJ8 A;  5JDG A;  5JDF A;  2L10 A;  3AT7 A;  3PF0 A;  5JDL A;  5JDM A;  5HXC A;  3V5U A;  4ONR A;  5HWX A;  4F7G B;  2X0C A;  3WSC A;  3DYJ A;  2L7N A;  3WUR A;  1SJ7 A;  5HXR A;  2XQY A;  2LQU A;  5HWY A;  4BGO A;  3PHF 1;  5HXH A;  2MTC A;  3V5S A;  4W8P A;  3VJZ A;  5JDQ A;  5JDH A;  5FZT A;  3M1C A;  5HXS A;  5HXE A;  2KVP A;  5T1D A;  4ECG A;  3FYQ A;  2KGX A;  5HYA A; 
#chains in the Genus database with same CATH homology
 2L10 A;  1SJ7 A;  2KBB A;  5FZT A;  3AY5 A;  1SJ8 A;  2KVP A;  2X0C A;  4F7G B;  3DYJ A;  3FYQ A;  2KGX A;  4W8P A;  2L7N A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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