1SJ7A

Crystal structure of talin rod 482-655
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
167
structure length
167
Chain Sequence
LTSAQQALTGTINSSMQAVQAAQATLDDFETLPPLGQDAASKAWRKNKMDESKHEIHSQVDAITAGTASVVNLTAGDPAETDYTAVGCAVTTISSNLTEMSRGVKLLAALLEDEGGNGRPLLQAAKGLAGAVSELLRSAQPASAEPRQNLLQAAGNVGQASGELLQQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle
pubmed doi rcsb
molecule keywords Talin 1
molecule tags Structural protein
source organism Mus musculus
total genus 70
structure length 167
sequence length 167
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2004-03-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09141 Talin_middle Talin, middle domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1420.10 Mainly Alpha Up-down Bundle A middle domain of Talin 1 Talin, central domain 1sj7A00
3DYJA 2L7NA 3FYQA 2KGXA 2X0CA 1SJ8A 2KBBA 2KVPA 4W8PA 4F7GB 5FZTA 2L10A 3AY5A 1SJ7A
chains in the Genus database with same CATH superfamily
3DYJA 4ONRA 5JDFA 3PF0A 2L10A 5HXHA 3V5SA 3PHF1 5HWYA 5HWXA 3V5UA 5T1DA 3WURA 4ECGA 3VJZA 4BGOA 4W8PA 2MTCA 5JDGA 2KGXA 5HXRA 3WSCA 5HYAA 2KBBA 2KVPA 2LQUA 4F7GB 5JDMA 5HXEA 3AT7A 5JDQA 5JDNA 2L7NA 3FYQA 2X0CA 1SJ8A 5JDHA 5HXSA 5HXCA 3M1CA 5FZTA 2XQYA 5JDLA 3AY5A 1SJ7A
chains in the Genus database with same CATH topology
3DYJA 2L7NA 3FYQA 2KGXA 2X0CA 1SJ8A 2KBBA 2KVPA 4W8PA 4F7GB 5FZTA 2L10A 3AY5A 1SJ7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3DYJ A;  2L7N A;  3FYQ A;  2KGX A;  2X0C A;  1SJ8 A;  2KBB A;  2KVP A;  4W8P A;  4F7G B;  5FZT A;  2L10 A;  3AY5 A;  1SJ7 A; 
#chains in the Genus database with same CATH topology
 3DYJ A;  4ONR A;  5JDF A;  3PF0 A;  2L10 A;  5HXH A;  3V5S A;  3PHF 1;  5HWY A;  5HWX A;  3V5U A;  5T1D A;  3WUR A;  4ECG A;  3VJZ A;  4BGO A;  4W8P A;  2MTC A;  5JDG A;  2KGX A;  5HXR A;  3WSC A;  5HYA A;  2KBB A;  2KVP A;  2LQU A;  4F7G B;  5JDM A;  5HXE A;  3AT7 A;  5JDQ A;  5JDN A;  2L7N A;  3FYQ A;  2X0C A;  1SJ8 A;  5JDH A;  5HXS A;  5HXC A;  3M1C A;  5FZT A;  2XQY A;  5JDL A;  3AY5 A;  1SJ7 A; 
#chains in the Genus database with same CATH homology
 3DYJ A;  2L7N A;  3FYQ A;  2KGX A;  2X0C A;  1SJ8 A;  2KBB A;  2KVP A;  4W8P A;  4F7G B;  5FZT A;  2L10 A;  3AY5 A;  1SJ7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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