1SJ7A

Crystal structure of talin rod 482-655
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
167
structure length
167
Chain Sequence
LTSAQQALTGTINSSMQAVQAAQATLDDFETLPPLGQDAASKAWRKNKMDESKHEIHSQVDAITAGTASVVNLTAGDPAETDYTAVGCAVTTISSNLTEMSRGVKLLAALLEDEGGNGRPLLQAAKGLAGAVSELLRSAQPASAEPRQNLLQAAGNVGQASGELLQQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle
pubmed doi rcsb
molecule keywords Talin 1
molecule tags Structural protein
source organism Mus musculus
total genus 70
structure length 167
sequence length 167
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2004-03-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09141 Talin_middle Talin, middle domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1420.10 Mainly Alpha Up-down Bundle A middle domain of Talin 1 Talin, central domain 1sj7A00
3FYQA 3DYJA 2KGXA 2X0CA 1SJ7A 1SJ8A 2L10A 2KBBA 2L7NA 3AY5A 4F7GB 4W8PA 5FZTA 2KVPA
chains in the Genus database with same CATH superfamily
5HXCA 3M1CA 5T1DA 3DYJA 2MTCA 1SJ7A 5JDFA 3VJZA 2KBBA 5HXSA 5JDNA 4ONRA 3V5UA 4BGOA 4ECGA 5FZTA 2X0CA 5HXHA 5HWXA 5JDLA 5JDHA 3PF0A 5HYAA 2LQUA 5HXEA 3WSCA 3V5SA 5HWYA 3PHF1 4F7GB 3WURA 5JDGA 3FYQA 2KGXA 2XQYA 5JDMA 2L10A 3AT7A 3AY5A 4W8PA 2KVPA 1SJ8A 5JDQA 5HXRA 2L7NA
chains in the Genus database with same CATH topology
3FYQA 3DYJA 2KGXA 2X0CA 1SJ7A 1SJ8A 2L10A 2KBBA 2L7NA 3AY5A 4F7GB 4W8PA 5FZTA 2KVPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3FYQ A;  3DYJ A;  2KGX A;  2X0C A;  1SJ7 A;  1SJ8 A;  2L10 A;  2KBB A;  2L7N A;  3AY5 A;  4F7G B;  4W8P A;  5FZT A;  2KVP A; 
#chains in the Genus database with same CATH topology
 5HXC A;  3M1C A;  5T1D A;  3DYJ A;  2MTC A;  1SJ7 A;  5JDF A;  3VJZ A;  2KBB A;  5HXS A;  5JDN A;  4ONR A;  3V5U A;  4BGO A;  4ECG A;  5FZT A;  2X0C A;  5HXH A;  5HWX A;  5JDL A;  5JDH A;  3PF0 A;  5HYA A;  2LQU A;  5HXE A;  3WSC A;  3V5S A;  5HWY A;  3PHF 1;  4F7G B;  3WUR A;  5JDG A;  3FYQ A;  2KGX A;  2XQY A;  5JDM A;  2L10 A;  3AT7 A;  3AY5 A;  4W8P A;  2KVP A;  1SJ8 A;  5JDQ A;  5HXR A;  2L7N A; 
#chains in the Genus database with same CATH homology
 3FYQ A;  3DYJ A;  2KGX A;  2X0C A;  1SJ7 A;  1SJ8 A;  2L10 A;  2KBB A;  2L7N A;  3AY5 A;  4F7G B;  4W8P A;  5FZT A;  2KVP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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