1SJ7A

Crystal structure of talin rod 482-655
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
167
structure length
167
Chain Sequence
LTSAQQALTGTINSSMQAVQAAQATLDDFETLPPLGQDAASKAWRKNKMDESKHEIHSQVDAITAGTASVVNLTAGDPAETDYTAVGCAVTTISSNLTEMSRGVKLLAALLEDEGGNGRPLLQAAKGLAGAVSELLRSAQPASAEPRQNLLQAAGNVGQASGELLQQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle
pubmed doi rcsb
molecule tags Structural protein
source organism Mus musculus
molecule keywords Talin 1
total genus 70
structure length 167
sequence length 167
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2004-03-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09141 Talin_middle Talin, middle domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1420.10 Mainly Alpha Up-down Bundle A middle domain of Talin 1 Talin, central domain 1sj7A00
1SJ8A 3FYQA 1SJ7A 2KBBA 2KGXA 2L10A 3AY5A 3DYJA 4W8PA 2L7NA 4F7GB 5FZTA 2X0CA 2KVPA
chains in the Genus database with same CATH superfamily
5HXEA 5HXRA 5HXSA 2LQUA 4W8PA 1SJ7A 2KBBA 3AY5A 3DYJA 3WURA 5JDQA 2L7NA 5JDNA 4ONRA 5JDHA 3V5UA 3M1CA 5HXCA 2L10A 3AT7A 3PHF1 4F7GB 2MTCA 2X0CA 3PF0A 5HYAA 5HWYA 5HWXA 4ECGA 3V5SA 3FYQA 5JDLA 5T1DA 5HXHA 2KVPA 5JDFA 1SJ8A 4BGOA 5JDGA 2XQYA 2KGXA 3WSCA 3VJZA 5JDMA 5FZTA
chains in the Genus database with same CATH topology
1SJ8A 3FYQA 1SJ7A 2KBBA 2KGXA 2L10A 3AY5A 3DYJA 4W8PA 2L7NA 4F7GB 5FZTA 2X0CA 2KVPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1SJ8 A;  3FYQ A;  1SJ7 A;  2KBB A;  2KGX A;  2L10 A;  3AY5 A;  3DYJ A;  4W8P A;  2L7N A;  4F7G B;  5FZT A;  2X0C A;  2KVP A; 
#chains in the Genus database with same CATH topology
 5HXE A;  5HXR A;  5HXS A;  2LQU A;  4W8P A;  1SJ7 A;  2KBB A;  3AY5 A;  3DYJ A;  3WUR A;  5JDQ A;  2L7N A;  5JDN A;  4ONR A;  5JDH A;  3V5U A;  3M1C A;  5HXC A;  2L10 A;  3AT7 A;  3PHF 1;  4F7G B;  2MTC A;  2X0C A;  3PF0 A;  5HYA A;  5HWY A;  5HWX A;  4ECG A;  3V5S A;  3FYQ A;  5JDL A;  5T1D A;  5HXH A;  2KVP A;  5JDF A;  1SJ8 A;  4BGO A;  5JDG A;  2XQY A;  2KGX A;  3WSC A;  3VJZ A;  5JDM A;  5FZT A; 
#chains in the Genus database with same CATH homology
 1SJ8 A;  3FYQ A;  1SJ7 A;  2KBB A;  2KGX A;  2L10 A;  3AY5 A;  3DYJ A;  4W8P A;  2L7N A;  4F7G B;  5FZT A;  2X0C A;  2KVP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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