4F7GB

Crystal structure of talin autoinhibition complex
Total Genus 73
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
73
sequence length
170
structure length
170
Chain Sequence
APGQLECETAIAALNSCLRDLDQASLAAVSQQLAPREGISQEALHTQMLTAVQEISHLIEPLASAARAEASQLGHKVSQMAQYFEPLTLAAVGAASKTLSHPQQMALLDQTKTLAESALQLLYTAKEAGGNPKQAAHTQEALEEAVQMMTEAVEDLTTTLNEAASAAGVV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Cell adhesion
molecule keywords Talin-1
publication title A novel membrane-dependent on/off switch mechanism of talin FERM domain at sites of cell adhesion.
pubmed doi rcsb
source organism Mus musculus
total genus 73
structure length 170
sequence length 170
ec nomenclature
pdb deposition date 2012-05-16
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1420.10 Mainly Alpha Up-down Bundle A middle domain of Talin 1 Talin, central domain 4f7gB00
2X0CA 2KGXA 4W8PA 5FZTA 2KVPA 2L7NA 4F7GB 2KBBA 1SJ8A 3AY5A 3DYJA 2L10A 1SJ7A 3FYQA
chains in the Genus database with same CATH superfamily
4ONRA 5HWYA 2KBBA 5JDLA 5JDMA 3WURA 2X0CA 3VJZA 5JDHA 4W8PA 5FZTA 2KVPA 3V5SA 3PHF1 3V5UA 5JDQA 1SJ8A 5JDFA 3PF0A 5HXCA 3WSCA 5HXSA 5HXEA 2MTCA 2KGXA 4ECGA 5HXHA 5JDNA 5JDGA 2LQUA 5HXRA 3M1CA 3DYJA 2L10A 3AT7A 1SJ7A 5HWXA 3FYQA 2L7NA 5HYAA 4F7GB 5T1DA 3AY5A 2XQYA 4BGOA
chains in the Genus database with same CATH topology
2X0CA 2KGXA 4W8PA 5FZTA 2KVPA 2L7NA 4F7GB 2KBBA 1SJ8A 3AY5A 3DYJA 2L10A 1SJ7A 3FYQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2X0C A;  2KGX A;  4W8P A;  5FZT A;  2KVP A;  2L7N A;  4F7G B;  2KBB A;  1SJ8 A;  3AY5 A;  3DYJ A;  2L10 A;  1SJ7 A;  3FYQ A; 
#chains in the Genus database with same CATH topology
 4ONR A;  5HWY A;  2KBB A;  5JDL A;  5JDM A;  3WUR A;  2X0C A;  3VJZ A;  5JDH A;  4W8P A;  5FZT A;  2KVP A;  3V5S A;  3PHF 1;  3V5U A;  5JDQ A;  1SJ8 A;  5JDF A;  3PF0 A;  5HXC A;  3WSC A;  5HXS A;  5HXE A;  2MTC A;  2KGX A;  4ECG A;  5HXH A;  5JDN A;  5JDG A;  2LQU A;  5HXR A;  3M1C A;  3DYJ A;  2L10 A;  3AT7 A;  1SJ7 A;  5HWX A;  3FYQ A;  2L7N A;  5HYA A;  4F7G B;  5T1D A;  3AY5 A;  2XQY A;  4BGO A; 
#chains in the Genus database with same CATH homology
 2X0C A;  2KGX A;  4W8P A;  5FZT A;  2KVP A;  2L7N A;  4F7G B;  2KBB A;  1SJ8 A;  3AY5 A;  3DYJ A;  2L10 A;  1SJ7 A;  3FYQ A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...