4F7GB

Crystal structure of talin autoinhibition complex
Total Genus 73
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
73
sequence length
170
structure length
170
Chain Sequence
APGQLECETAIAALNSCLRDLDQASLAAVSQQLAPREGISQEALHTQMLTAVQEISHLIEPLASAARAEASQLGHKVSQMAQYFEPLTLAAVGAASKTLSHPQQMALLDQTKTLAESALQLLYTAKEAGGNPKQAAHTQEALEEAVQMMTEAVEDLTTTLNEAASAAGVV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title A novel membrane-dependent on/off switch mechanism of talin FERM domain at sites of cell adhesion.
pubmed doi rcsb
molecule tags Cell adhesion
source organism Mus musculus
molecule keywords Talin-1
total genus 73
structure length 170
sequence length 170
ec nomenclature
pdb deposition date 2012-05-16
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1420.10 Mainly Alpha Up-down Bundle A middle domain of Talin 1 Talin, central domain 4f7gB00
3DYJA 4W8PA 2L10A 1SJ7A 2KVPA 2L7NA 5FZTA 2X0CA 2KGXA 3AY5A 2KBBA 3FYQA 1SJ8A 4F7GB
chains in the Genus database with same CATH superfamily
3DYJA 3VJZA 5JDLA 5HWYA 2XQYA 3V5SA 3AY5A 2KBBA 3FYQA 2LQUA 4BGOA 5JDMA 5HXEA 5HXSA 3PF0A 5HWXA 5JDNA 2L10A 5FZTA 3WSCA 3PHF1 2KGXA 4ECGA 5HYAA 5JDFA 1SJ8A 5HXCA 2MTCA 2L7NA 3V5UA 2X0CA 3WURA 3M1CA 4W8PA 4ONRA 3AT7A 5HXHA 5T1DA 5JDQA 1SJ7A 5HXRA 2KVPA 5JDGA 5JDHA 4F7GB
chains in the Genus database with same CATH topology
3DYJA 4W8PA 2L10A 1SJ7A 2KVPA 2L7NA 5FZTA 2X0CA 2KGXA 3AY5A 2KBBA 3FYQA 1SJ8A 4F7GB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3DYJ A;  4W8P A;  2L10 A;  1SJ7 A;  2KVP A;  2L7N A;  5FZT A;  2X0C A;  2KGX A;  3AY5 A;  2KBB A;  3FYQ A;  1SJ8 A;  4F7G B; 
#chains in the Genus database with same CATH topology
 3DYJ A;  3VJZ A;  5JDL A;  5HWY A;  2XQY A;  3V5S A;  3AY5 A;  2KBB A;  3FYQ A;  2LQU A;  4BGO A;  5JDM A;  5HXE A;  5HXS A;  3PF0 A;  5HWX A;  5JDN A;  2L10 A;  5FZT A;  3WSC A;  3PHF 1;  2KGX A;  4ECG A;  5HYA A;  5JDF A;  1SJ8 A;  5HXC A;  2MTC A;  2L7N A;  3V5U A;  2X0C A;  3WUR A;  3M1C A;  4W8P A;  4ONR A;  3AT7 A;  5HXH A;  5T1D A;  5JDQ A;  1SJ7 A;  5HXR A;  2KVP A;  5JDG A;  5JDH A;  4F7G B; 
#chains in the Genus database with same CATH homology
 3DYJ A;  4W8P A;  2L10 A;  1SJ7 A;  2KVP A;  2L7N A;  5FZT A;  2X0C A;  2KGX A;  3AY5 A;  2KBB A;  3FYQ A;  1SJ8 A;  4F7G B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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