2KVPA

Nmr structure of the talin vbs3 domain, 1815-1973
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
165
structure length
165
Chain Sequence
GIDPFTNEAASAAGVVGGMVDSITQAINQLDEGPMGDPEGSFVDYQTTMVRTAKAIAVTVQEMVTKSNTSPEELGPLANQLTSDYGRLASQAKPAAVAAENEEIGAHIKHRVQELGHGCSALVTKAGALQCSPSDVYTKKELIECARRVSEKVSHVLAALQAGNR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The domain structure of talin: Residues 1815-1973 form a five-helix bundle containing a cryptic vinculin-binding site.
pubmed doi rcsb
molecule keywords Talin-1
molecule tags Structural protein
source organism Mus musculus
total genus 57
structure length 165
sequence length 165
ec nomenclature
pdb deposition date 2010-03-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08913 VBS Vinculin Binding Site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1420.10 Mainly Alpha Up-down Bundle A middle domain of Talin 1 Talin, central domain 2kvpA00
2KVPA 3FYQA 2X0CA 2L7NA 5FZTA 2KGXA 1SJ8A 2L10A 3DYJA 4W8PA 2KBBA 3AY5A 1SJ7A 4F7GB
chains in the Genus database with same CATH superfamily
3FYQA 5HYAA 3AT7A 1SJ8A 5JDNA 5JDFA 5JDLA 3DYJA 3AY5A 4W8PA 2LQUA 5HXHA 3PHF1 2KVPA 5HWYA 4ONRA 2KGXA 3WSCA 2L10A 2MTCA 3PF0A 5HXEA 1SJ7A 3VJZA 2L7NA 5HWXA 3WURA 5HXCA 5HXRA 5JDGA 3V5SA 5JDHA 4ECGA 2XQYA 2X0CA 5FZTA 4BGOA 5JDMA 5HXSA 3V5UA 5JDQA 2KBBA 4F7GB 5T1DA 3M1CA
chains in the Genus database with same CATH topology
2KVPA 3FYQA 2X0CA 2L7NA 5FZTA 2KGXA 1SJ8A 2L10A 3DYJA 4W8PA 2KBBA 3AY5A 1SJ7A 4F7GB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KVP A;  3FYQ A;  2X0C A;  2L7N A;  5FZT A;  2KGX A;  1SJ8 A;  2L10 A;  3DYJ A;  4W8P A;  2KBB A;  3AY5 A;  1SJ7 A;  4F7G B; 
#chains in the Genus database with same CATH topology
 3FYQ A;  5HYA A;  3AT7 A;  1SJ8 A;  5JDN A;  5JDF A;  5JDL A;  3DYJ A;  3AY5 A;  4W8P A;  2LQU A;  5HXH A;  3PHF 1;  2KVP A;  5HWY A;  4ONR A;  2KGX A;  3WSC A;  2L10 A;  2MTC A;  3PF0 A;  5HXE A;  1SJ7 A;  3VJZ A;  2L7N A;  5HWX A;  3WUR A;  5HXC A;  5HXR A;  5JDG A;  3V5S A;  5JDH A;  4ECG A;  2XQY A;  2X0C A;  5FZT A;  4BGO A;  5JDM A;  5HXS A;  3V5U A;  5JDQ A;  2KBB A;  4F7G B;  5T1D A;  3M1C A; 
#chains in the Genus database with same CATH homology
 2KVP A;  3FYQ A;  2X0C A;  2L7N A;  5FZT A;  2KGX A;  1SJ8 A;  2L10 A;  3DYJ A;  4W8P A;  2KBB A;  3AY5 A;  1SJ7 A;  4F7G B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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