2KVPA

Nmr structure of the talin vbs3 domain, 1815-1973
Total Genus 57
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
165
structure length
165
Chain Sequence
GIDPFTNEAASAAGVVGGMVDSITQAINQLDEGPMGDPEGSFVDYQTTMVRTAKAIAVTVQEMVTKSNTSPEELGPLANQLTSDYGRLASQAKPAAVAAENEEIGAHIKHRVQELGHGCSALVTKAGALQCSPSDVYTKKELIECARRVSEKVSHVLAALQAGNR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The domain structure of talin: Residues 1815-1973 form a five-helix bundle containing a cryptic vinculin-binding site.
pubmed doi rcsb
molecule keywords Talin-1
molecule tags Structural protein
source organism Mus musculus
total genus 57
structure length 165
sequence length 165
ec nomenclature
pdb deposition date 2010-03-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08913 VBS Vinculin Binding Site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1420.10 Mainly Alpha Up-down Bundle A middle domain of Talin 1 Talin, central domain 2kvpA00
2L7NA 2KVPA 5FZTA 2X0CA 3AY5A 3FYQA 2L10A 2KGXA 4W8PA 4F7GB 2KBBA 1SJ8A 3DYJA 1SJ7A
chains in the Genus database with same CATH superfamily
5HXSA 4BGOA 5JDNA 5JDHA 2MTCA 5JDGA 2L7NA 3AT7A 2KVPA 5FZTA 2X0CA 4ECGA 3FYQA 5HXCA 3PF0A 4W8PA 5T1DA 5HXEA 4F7GB 3WSCA 5HWYA 1SJ8A 1SJ7A 2XQYA 5HYAA 5HWXA 5HXHA 3AY5A 2L10A 5JDFA 3V5SA 4ONRA 3VJZA 2KBBA 5JDQA 3DYJA 5HXRA 3M1CA 2KGXA 5JDMA 3PHF1 3WURA 5JDLA 2LQUA 3V5UA
chains in the Genus database with same CATH topology
2L7NA 2KVPA 5FZTA 2X0CA 3AY5A 3FYQA 2L10A 2KGXA 4W8PA 4F7GB 2KBBA 1SJ8A 3DYJA 1SJ7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2L7N A;  2KVP A;  5FZT A;  2X0C A;  3AY5 A;  3FYQ A;  2L10 A;  2KGX A;  4W8P A;  4F7G B;  2KBB A;  1SJ8 A;  3DYJ A;  1SJ7 A; 
#chains in the Genus database with same CATH topology
 5HXS A;  4BGO A;  5JDN A;  5JDH A;  2MTC A;  5JDG A;  2L7N A;  3AT7 A;  2KVP A;  5FZT A;  2X0C A;  4ECG A;  3FYQ A;  5HXC A;  3PF0 A;  4W8P A;  5T1D A;  5HXE A;  4F7G B;  3WSC A;  5HWY A;  1SJ8 A;  1SJ7 A;  2XQY A;  5HYA A;  5HWX A;  5HXH A;  3AY5 A;  2L10 A;  5JDF A;  3V5S A;  4ONR A;  3VJZ A;  2KBB A;  5JDQ A;  3DYJ A;  5HXR A;  3M1C A;  2KGX A;  5JDM A;  3PHF 1;  3WUR A;  5JDL A;  2LQU A;  3V5U A; 
#chains in the Genus database with same CATH homology
 2L7N A;  2KVP A;  5FZT A;  2X0C A;  3AY5 A;  3FYQ A;  2L10 A;  2KGX A;  4W8P A;  4F7G B;  2KBB A;  1SJ8 A;  3DYJ A;  1SJ7 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...