1V53A

The crystal structure of 3-isopropylmalate dehydrogenase from bacillus coagulans
Total Genus 125
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
125
sequence length
356
structure length
356
Chain Sequence
MKMKLAVLPGDGIGPEVMDAAIRVLKTVLDNDGHEAVFENALIGGAAIDEAGTPLPEETLDICRRSDAILLGAVGGPKWDHNPASLRPEKGLLGLRKEMGLFANLRPVKAYATLLNASPLKRERVENVDLVIVRELTGGLYFGRPSERRGPGENEVVDTLAYTREEIERIIEKAFQLAQIRRKKLASVDKANVLESSRMWREIAEETAKKYPDVELSHMLVDSTSMQLIANPGQFDVIVTENMFGDILSDEASVITGSLGMLPSASLRSDRFGMYEPVHGSAPDIAGQGKANPLGTVLSAALMLRYSFGLEKEAAAIEKAVDDVLQDGYCTGDLQVANGKVVSTIELTDRLIEKLN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The crystal structure of 3-isopropylmalate dehydrogenase from Bacillus coagulans
rcsb
molecule tags Oxidoreductase
source organism Bacillus coagulans
molecule keywords 3-isopropylmalate dehydrogenase
total genus 125
structure length 356
sequence length 356
chains with identical sequence B
ec nomenclature ec 1.1.1.85: 3-isopropylmalate dehydrogenase.
pdb deposition date 2003-11-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00180 Iso_dh Isocitrate/isopropylmalate dehydrogenase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.718.10 Alpha Beta 3-Layer(aba) Sandwich Isopropylmalate Dehydrogenase Isopropylmalate Dehydrogenase 1v53A00
8ICDA 2Y42A 1IDFA 1OSJA 6ICDA 3U1HA 3R8WA 3U9EA 4AOVA 1IKAA 1R8KA 1CW1A 3US8A 4AOUA 1AI3A 1XAAA 3WZYA 4AOYA 1OSIA 2AYQA 4IWHA 2IV0A 4HCXA 4P69C 1AI2A 3LXYA 4WUOA 1VLCA 5GRLB 5HN4A 1XADA 1DR0A 2D4VA 1CW7A 1A05A 5GRHB 5J34A 1WALA 1PS6A 5GRLA 3VL2A 4ATYA 1XGVA 3TNGA 3VMLA 1V53A 1IDEA 5GRHA 3MAPA 5HN5A 1SJSA 1YCOA 1XKDA 5LGEA 1IDMA 5GREB 4Y1PA 3MARA 4XRXA 3WZVA 1IPDA 5I95A 2Y41A 3BLXB 1WPWA 1CM7A 1PB1A 2Y3ZA 5DE1A 4BNPA 1ZORA 5GREA 4JA8A 1HEXA 1GC9A 2QFVA 4F7IA 4I3LA 5ICDA 1PS7A 3ASJA 1W0DA 1PB3A 4AJAA 1YXOA 3BLXA 4L04A 1X0LA 1V5BA 3LCBC 2DHTA 4KZOA 4JQPA 2E5MA 3VL6A 4YB4A 3WZXA 4AJ3A 1TYOA 2HI1A 2ZTWA 5L57A 2D1CA 4UMYA 1G2UA 2UXQA 5L58A 2Y40A 3VL4A 1HQSA 3VKZA 1DPZA 5K10A 3MASB 4I3KA 3VMJA 3FMXX 4UMXA 3INMA 2E0CA 3FLKA 1GRPA 1T0LA 5HN3A 3ICDA 3UF6A 1P8FA 4AJBA 2UXRA 3MASA 4L06A 3DMSA 3VL3A 5J32A 9ICDA 2QFWA 4ICDA 5HN6A 3AH3A 1U7NA 4XS3A 5K11A 1LWDA 1IDDA 5GRIB 1PTMA 2QFXA 7ICDA 4AJRA 1CW4A 1GROA 5GRFB 1BL5A 3TY4A 1GC8A 1ISOA 3BLVB 3WZWA 1DR8A 5I96A 1T09A 4AJSA 1V94A 1CNZA 3TY3A 3VL7A 2G4OA 1XABA 1IDCA 5J33A 5GRIA 4L03A 3UDOA 3UDUA 2QFYA 4XXVA 5GRFA 3BLVA 3TSNA 3VMKA 1VI1A 4AJCA 1XACA 1HJ6A
chains in the Genus database with same CATH superfamily
8ICDA 2Y42A 1IDFA 1OSJA 6ICDA 3U1HA 3R8WA 3U9EA 4AOVA 1IKAA 1R8KA 1CW1A 3US8A 4AOUA 1AI3A 1XAAA 3WZYA 4AOYA 1OSIA 2AYQA 4IWHA 2IV0A 4HCXA 4P69C 1AI2A 3LXYA 4WUOA 1VLCA 5GRLB 5HN4A 1XADA 1DR0A 2D4VA 1CW7A 1A05A 5GRHB 5J34A 1WALA 1PS6A 5GRLA 3VL2A 4ATYA 1XGVA 3TNGA 3VMLA 1V53A 1IDEA 5GRHA 3MAPA 5HN5A 1SJSA 1YCOA 1XKDA 5LGEA 1IDMA 5GREB 4Y1PA 3MARA 4XRXA 3WZVA 1IPDA 5I95A 2Y41A 3BLXB 1WPWA 1CM7A 1PB1A 2Y3ZA 5DE1A 4BNPA 1ZORA 5GREA 4JA8A 1HEXA 1GC9A 2QFVA 4F7IA 4I3LA 5ICDA 1PS7A 3ASJA 1W0DA 1PB3A 4AJAA 1YXOA 3BLXA 4L04A 1X0LA 1V5BA 3LCBC 2DHTA 4KZOA 4JQPA 2E5MA 3VL6A 4YB4A 3WZXA 4AJ3A 1TYOA 2HI1A 2ZTWA 5L57A 2D1CA 4UMYA 1G2UA 2UXQA 5L58A 2Y40A 3VL4A 1HQSA 3VKZA 1DPZA 5K10A 3MASB 4I3KA 3VMJA 3FMXX 4UMXA 3INMA 2E0CA 3FLKA 1GRPA 1T0LA 5HN3A 3ICDA 3UF6A 1P8FA 4AJBA 2UXRA 3MASA 4L06A 3DMSA 3VL3A 5J32A 9ICDA 2QFWA 4ICDA 5HN6A 3AH3A 1U7NA 4XS3A 5K11A 1LWDA 1IDDA 5GRIB 1PTMA 2QFXA 7ICDA 4AJRA 1CW4A 1GROA 5GRFB 1BL5A 3TY4A 1GC8A 1ISOA 3BLVB 3WZWA 1DR8A 5I96A 1T09A 4AJSA 1V94A 1CNZA 3TY3A 3VL7A 2G4OA 1XABA 1IDCA 5J33A 5GRIA 4L03A 3UDOA 3UDUA 2QFYA 4XXVA 5GRFA 3BLVA 3TSNA 3VMKA 1VI1A 4AJCA 1XACA 1HJ6A
chains in the Genus database with same CATH topology
8ICDA 2Y42A 1IDFA 1OSJA 6ICDA 3U1HA 3R8WA 3U9EA 4AOVA 1IKAA 1R8KA 1CW1A 3US8A 4AOUA 1AI3A 1XAAA 3WZYA 4AOYA 1OSIA 2AYQA 4IWHA 2IV0A 4HCXA 4P69C 1AI2A 3LXYA 4WUOA 1VLCA 5GRLB 5HN4A 1XADA 1DR0A 2D4VA 1CW7A 1A05A 5GRHB 5J34A 1WALA 1PS6A 5GRLA 3VL2A 4ATYA 1XGVA 3TNGA 3VMLA 1V53A 1IDEA 5GRHA 3MAPA 5HN5A 1SJSA 1YCOA 1XKDA 5LGEA 1IDMA 5GREB 4Y1PA 3MARA 4XRXA 3WZVA 1IPDA 5I95A 2Y41A 3BLXB 1WPWA 1CM7A 1PB1A 2Y3ZA 5DE1A 4BNPA 1ZORA 5GREA 4JA8A 1HEXA 1GC9A 2QFVA 4F7IA 4I3LA 5ICDA 1PS7A 3ASJA 1W0DA 1PB3A 4AJAA 1YXOA 3BLXA 4L04A 1X0LA 1V5BA 3LCBC 2DHTA 4KZOA 4JQPA 2E5MA 3VL6A 4YB4A 3WZXA 4AJ3A 1TYOA 2HI1A 2ZTWA 5L57A 2D1CA 4UMYA 1G2UA 2UXQA 5L58A 2Y40A 3VL4A 1HQSA 3VKZA 1DPZA 5K10A 3MASB 4I3KA 3VMJA 3FMXX 4UMXA 3INMA 2E0CA 3FLKA 1GRPA 1T0LA 5HN3A 3ICDA 3UF6A 1P8FA 4AJBA 2UXRA 3MASA 4L06A 3DMSA 3VL3A 5J32A 9ICDA 2QFWA 4ICDA 5HN6A 3AH3A 1U7NA 4XS3A 5K11A 1LWDA 1IDDA 5GRIB 1PTMA 2QFXA 7ICDA 4AJRA 1CW4A 1GROA 5GRFB 1BL5A 3TY4A 1GC8A 1ISOA 3BLVB 3WZWA 1DR8A 5I96A 1T09A 4AJSA 1V94A 1CNZA 3TY3A 3VL7A 2G4OA 1XABA 1IDCA 5J33A 5GRIA 4L03A 3UDOA 3UDUA 2QFYA 4XXVA 5GRFA 3BLVA 3TSNA 3VMKA 1VI1A 4AJCA 1XACA 1HJ6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 8ICD A;  2Y42 A;  1IDF A;  1OSJ A;  6ICD A;  3U1H A;  3R8W A;  3U9E A;  4AOV A;  1IKA A;  1R8K A;  1CW1 A;  3US8 A;  4AOU A;  1AI3 A;  1XAA A;  3WZY A;  4AOY A;  1OSI A;  2AYQ A;  4IWH A;  2IV0 A;  4HCX A;  4P69 C;  1AI2 A;  3LXY A;  4WUO A;  1VLC A;  5GRL B;  5HN4 A;  1XAD A;  1DR0 A;  2D4V A;  1CW7 A;  1A05 A;  5GRH B;  5J34 A;  1WAL A;  1PS6 A;  5GRL A;  3VL2 A;  4ATY A;  1XGV A;  3TNG A;  3VML A;  1V53 A;  1IDE A;  5GRH A;  3MAP A;  5HN5 A;  1SJS A;  1YCO A;  1XKD A;  5LGE A;  1IDM A;  5GRE B;  4Y1P A;  3MAR A;  4XRX A;  3WZV A;  1IPD A;  5I95 A;  2Y41 A;  3BLX B;  1WPW A;  1CM7 A;  1PB1 A;  2Y3Z A;  5DE1 A;  4BNP A;  1ZOR A;  5GRE A;  4JA8 A;  1HEX A;  1GC9 A;  2QFV A;  4F7I A;  4I3L A;  5ICD A;  1PS7 A;  3ASJ A;  1W0D A;  1PB3 A;  4AJA A;  1YXO A;  3BLX A;  4L04 A;  1X0L A;  1V5B A;  3LCB C;  2DHT A;  4KZO A;  4JQP A;  2E5M A;  3VL6 A;  4YB4 A;  3WZX A;  4AJ3 A;  1TYO A;  2HI1 A;  2ZTW A;  5L57 A;  2D1C A;  4UMY A;  1G2U A;  2UXQ A;  5L58 A;  2Y40 A;  3VL4 A;  1HQS A;  3VKZ A;  1DPZ A;  5K10 A;  3MAS B;  4I3K A;  3VMJ A;  3FMX X;  4UMX A;  3INM A;  2E0C A;  3FLK A;  1GRP A;  1T0L A;  5HN3 A;  3ICD A;  3UF6 A;  1P8F A;  4AJB A;  2UXR A;  3MAS A;  4L06 A;  3DMS A;  3VL3 A;  5J32 A;  9ICD A;  2QFW A;  4ICD A;  5HN6 A;  3AH3 A;  1U7N A;  4XS3 A;  5K11 A;  1LWD A;  1IDD A;  5GRI B;  1PTM A;  2QFX A;  7ICD A;  4AJR A;  1CW4 A;  1GRO A;  5GRF B;  1BL5 A;  3TY4 A;  1GC8 A;  1ISO A;  3BLV B;  3WZW A;  1DR8 A;  5I96 A;  1T09 A;  4AJS A;  1V94 A;  1CNZ A;  3TY3 A;  3VL7 A;  2G4O A;  1XAB A;  1IDC A;  5J33 A;  5GRI A;  4L03 A;  3UDO A;  3UDU A;  2QFY A;  4XXV A;  5GRF A;  3BLV A;  3TSN A;  3VMK A;  1VI1 A;  4AJC A;  1XAC A;  1HJ6 A; 
#chains in the Genus database with same CATH topology
 8ICD A;  2Y42 A;  1IDF A;  1OSJ A;  6ICD A;  3U1H A;  3R8W A;  3U9E A;  4AOV A;  1IKA A;  1R8K A;  1CW1 A;  3US8 A;  4AOU A;  1AI3 A;  1XAA A;  3WZY A;  4AOY A;  1OSI A;  2AYQ A;  4IWH A;  2IV0 A;  4HCX A;  4P69 C;  1AI2 A;  3LXY A;  4WUO A;  1VLC A;  5GRL B;  5HN4 A;  1XAD A;  1DR0 A;  2D4V A;  1CW7 A;  1A05 A;  5GRH B;  5J34 A;  1WAL A;  1PS6 A;  5GRL A;  3VL2 A;  4ATY A;  1XGV A;  3TNG A;  3VML A;  1V53 A;  1IDE A;  5GRH A;  3MAP A;  5HN5 A;  1SJS A;  1YCO A;  1XKD A;  5LGE A;  1IDM A;  5GRE B;  4Y1P A;  3MAR A;  4XRX A;  3WZV A;  1IPD A;  5I95 A;  2Y41 A;  3BLX B;  1WPW A;  1CM7 A;  1PB1 A;  2Y3Z A;  5DE1 A;  4BNP A;  1ZOR A;  5GRE A;  4JA8 A;  1HEX A;  1GC9 A;  2QFV A;  4F7I A;  4I3L A;  5ICD A;  1PS7 A;  3ASJ A;  1W0D A;  1PB3 A;  4AJA A;  1YXO A;  3BLX A;  4L04 A;  1X0L A;  1V5B A;  3LCB C;  2DHT A;  4KZO A;  4JQP A;  2E5M A;  3VL6 A;  4YB4 A;  3WZX A;  4AJ3 A;  1TYO A;  2HI1 A;  2ZTW A;  5L57 A;  2D1C A;  4UMY A;  1G2U A;  2UXQ A;  5L58 A;  2Y40 A;  3VL4 A;  1HQS A;  3VKZ A;  1DPZ A;  5K10 A;  3MAS B;  4I3K A;  3VMJ A;  3FMX X;  4UMX A;  3INM A;  2E0C A;  3FLK A;  1GRP A;  1T0L A;  5HN3 A;  3ICD A;  3UF6 A;  1P8F A;  4AJB A;  2UXR A;  3MAS A;  4L06 A;  3DMS A;  3VL3 A;  5J32 A;  9ICD A;  2QFW A;  4ICD A;  5HN6 A;  3AH3 A;  1U7N A;  4XS3 A;  5K11 A;  1LWD A;  1IDD A;  5GRI B;  1PTM A;  2QFX A;  7ICD A;  4AJR A;  1CW4 A;  1GRO A;  5GRF B;  1BL5 A;  3TY4 A;  1GC8 A;  1ISO A;  3BLV B;  3WZW A;  1DR8 A;  5I96 A;  1T09 A;  4AJS A;  1V94 A;  1CNZ A;  3TY3 A;  3VL7 A;  2G4O A;  1XAB A;  1IDC A;  5J33 A;  5GRI A;  4L03 A;  3UDO A;  3UDU A;  2QFY A;  4XXV A;  5GRF A;  3BLV A;  3TSN A;  3VMK A;  1VI1 A;  4AJC A;  1XAC A;  1HJ6 A; 
#chains in the Genus database with same CATH homology
 8ICD A;  2Y42 A;  1IDF A;  1OSJ A;  6ICD A;  3U1H A;  3R8W A;  3U9E A;  4AOV A;  1IKA A;  1R8K A;  1CW1 A;  3US8 A;  4AOU A;  1AI3 A;  1XAA A;  3WZY A;  4AOY A;  1OSI A;  2AYQ A;  4IWH A;  2IV0 A;  4HCX A;  4P69 C;  1AI2 A;  3LXY A;  4WUO A;  1VLC A;  5GRL B;  5HN4 A;  1XAD A;  1DR0 A;  2D4V A;  1CW7 A;  1A05 A;  5GRH B;  5J34 A;  1WAL A;  1PS6 A;  5GRL A;  3VL2 A;  4ATY A;  1XGV A;  3TNG A;  3VML A;  1V53 A;  1IDE A;  5GRH A;  3MAP A;  5HN5 A;  1SJS A;  1YCO A;  1XKD A;  5LGE A;  1IDM A;  5GRE B;  4Y1P A;  3MAR A;  4XRX A;  3WZV A;  1IPD A;  5I95 A;  2Y41 A;  3BLX B;  1WPW A;  1CM7 A;  1PB1 A;  2Y3Z A;  5DE1 A;  4BNP A;  1ZOR A;  5GRE A;  4JA8 A;  1HEX A;  1GC9 A;  2QFV A;  4F7I A;  4I3L A;  5ICD A;  1PS7 A;  3ASJ A;  1W0D A;  1PB3 A;  4AJA A;  1YXO A;  3BLX A;  4L04 A;  1X0L A;  1V5B A;  3LCB C;  2DHT A;  4KZO A;  4JQP A;  2E5M A;  3VL6 A;  4YB4 A;  3WZX A;  4AJ3 A;  1TYO A;  2HI1 A;  2ZTW A;  5L57 A;  2D1C A;  4UMY A;  1G2U A;  2UXQ A;  5L58 A;  2Y40 A;  3VL4 A;  1HQS A;  3VKZ A;  1DPZ A;  5K10 A;  3MAS B;  4I3K A;  3VMJ A;  3FMX X;  4UMX A;  3INM A;  2E0C A;  3FLK A;  1GRP A;  1T0L A;  5HN3 A;  3ICD A;  3UF6 A;  1P8F A;  4AJB A;  2UXR A;  3MAS A;  4L06 A;  3DMS A;  3VL3 A;  5J32 A;  9ICD A;  2QFW A;  4ICD A;  5HN6 A;  3AH3 A;  1U7N A;  4XS3 A;  5K11 A;  1LWD A;  1IDD A;  5GRI B;  1PTM A;  2QFX A;  7ICD A;  4AJR A;  1CW4 A;  1GRO A;  5GRF B;  1BL5 A;  3TY4 A;  1GC8 A;  1ISO A;  3BLV B;  3WZW A;  1DR8 A;  5I96 A;  1T09 A;  4AJS A;  1V94 A;  1CNZ A;  3TY3 A;  3VL7 A;  2G4O A;  1XAB A;  1IDC A;  5J33 A;  5GRI A;  4L03 A;  3UDO A;  3UDU A;  2QFY A;  4XXV A;  5GRF A;  3BLV A;  3TSN A;  3VMK A;  1VI1 A;  4AJC A;  1XAC A;  1HJ6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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