1V66A

Solution structure of human p53 binding domain of pias-1
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
65
structure length
65
Chain Sequence
MADSAELKQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKIKELYRRRF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title NMR structure of the N-terminal domain of SUMO ligase PIAS1 and its interaction with tumor suppressor p53 and A/T-rich DNA oligomers
pubmed doi rcsb
molecule tags Ligase
source organism Homo sapiens
molecule keywords Protein inhibitor of activated STAT protein 1
total genus 20
structure length 65
sequence length 65
ec nomenclature
pdb deposition date 2003-11-27
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.720.30 Mainly Alpha Orthogonal Bundle Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 SAP domain 1v66A00
2KVDA 4UZWA 2WQGA 2KVUA 1JEQA 1JJRA 1ZBHA 2KVEA 2JVWA 2RNNA 2KW9A 4BITA 1H1JS 2RNOA 1V66A
chains in the Genus database with same CATH superfamily
4UZWA 2G80A 2KFVA 2JVWA 2KW9A 2LC3A 1GKUB 1A63A 1GL9B 2W51A 2RNOA 1E7LA 3FLGA 2QNCA 2KVDA 3QKJA 1ZS9A 2ODGC 1Y02A 1GJJA 5CIUA 1JEQA 2DK4A 1E7DA 1ZBHA 2A8VA 2MPHA 1JEIA 2LD7A 1V66A 1YNSA 1A62A 1H9EA 2WQGA 3LLRA 2KVUA 2QNFA 3L0OA 1JJRA 2ODCI 2HJQA 2KVEA 2RNNA 4BITA 1H1JS 1KHCA 1H9FA 1A8VA 1EN7A
chains in the Genus database with same CATH topology
2KVDA 4UZWA 2WQGA 2KVUA 1JEQA 1JJRA 1ZBHA 2KVEA 2JVWA 2RNNA 2KW9A 4BITA 1H1JS 2RNOA 1V66A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KVD A;  4UZW A;  2WQG A;  2KVU A;  1JEQ A;  1JJR A;  1ZBH A;  2KVE A;  2JVW A;  2RNN A;  2KW9 A;  4BIT A;  1H1J S;  2RNO A;  1V66 A; 
#chains in the Genus database with same CATH topology
 4UZW A;  2G80 A;  2KFV A;  2JVW A;  2KW9 A;  2LC3 A;  1GKU B;  1A63 A;  1GL9 B;  2W51 A;  2RNO A;  1E7L A;  3FLG A;  2QNC A;  2KVD A;  3QKJ A;  1ZS9 A;  2ODG C;  1Y02 A;  1GJJ A;  5CIU A;  1JEQ A;  2DK4 A;  1E7D A;  1ZBH A;  2A8V A;  2MPH A;  1JEI A;  2LD7 A;  1V66 A;  1YNS A;  1A62 A;  1H9E A;  2WQG A;  3LLR A;  2KVU A;  2QNF A;  3L0O A;  1JJR A;  2ODC I;  2HJQ A;  2KVE A;  2RNN A;  4BIT A;  1H1J S;  1KHC A;  1H9F A;  1A8V A;  1EN7 A; 
#chains in the Genus database with same CATH homology
 2KVD A;  4UZW A;  2WQG A;  2KVU A;  1JEQ A;  1JJR A;  1ZBH A;  2KVE A;  2JVW A;  2RNN A;  2KW9 A;  4BIT A;  1H1J S;  2RNO A;  1V66 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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