1V66A

Solution structure of human p53 binding domain of pias-1
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
65
structure length
65
Chain Sequence
MADSAELKQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKIKELYRRRF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title NMR structure of the N-terminal domain of SUMO ligase PIAS1 and its interaction with tumor suppressor p53 and A/T-rich DNA oligomers
pubmed doi rcsb
molecule keywords Protein inhibitor of activated STAT protein 1
molecule tags Ligase
source organism Homo sapiens
total genus 20
structure length 65
sequence length 65
ec nomenclature
pdb deposition date 2003-11-27
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.720.30 Mainly Alpha Orthogonal Bundle Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 SAP domain 1v66A00
1JEQA 2RNOA 1V66A 1ZBHA 2RNNA 2KW9A 2KVDA 4UZWA 4BITA 2JVWA 2KVEA 2KVUA 1JJRA 1H1JS 2WQGA
chains in the Genus database with same CATH superfamily
2DK4A 2G80A 2RNOA 1YNSA 3L0OA 1H9EA 2QNFA 4UZWA 3FLGA 2KVEA 2HJQA 2A8VA 1EN7A 2QNCA 1GJJA 1V66A 2RNNA 2W51A 2KW9A 1ZBHA 1A63A 1E7DA 4BITA 1Y02A 1A8VA 1E7LA 1H1JS 2LD7A 5CIUA 1JEQA 1GKUB 2KFVA 2ODCI 1ZS9A 2KVDA 2ODGC 2JVWA 1H9FA 2MPHA 2WQGA 1JEIA 3LLRA 2LC3A 2KVUA 1JJRA 1KHCA 3QKJA 1A62A 1GL9B
chains in the Genus database with same CATH topology
1JEQA 2RNOA 1V66A 1ZBHA 2RNNA 2KW9A 2KVDA 4UZWA 4BITA 2JVWA 2KVEA 2KVUA 1JJRA 1H1JS 2WQGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1JEQ A;  2RNO A;  1V66 A;  1ZBH A;  2RNN A;  2KW9 A;  2KVD A;  4UZW A;  4BIT A;  2JVW A;  2KVE A;  2KVU A;  1JJR A;  1H1J S;  2WQG A; 
#chains in the Genus database with same CATH topology
 2DK4 A;  2G80 A;  2RNO A;  1YNS A;  3L0O A;  1H9E A;  2QNF A;  4UZW A;  3FLG A;  2KVE A;  2HJQ A;  2A8V A;  1EN7 A;  2QNC A;  1GJJ A;  1V66 A;  2RNN A;  2W51 A;  2KW9 A;  1ZBH A;  1A63 A;  1E7D A;  4BIT A;  1Y02 A;  1A8V A;  1E7L A;  1H1J S;  2LD7 A;  5CIU A;  1JEQ A;  1GKU B;  2KFV A;  2ODC I;  1ZS9 A;  2KVD A;  2ODG C;  2JVW A;  1H9F A;  2MPH A;  2WQG A;  1JEI A;  3LLR A;  2LC3 A;  2KVU A;  1JJR A;  1KHC A;  3QKJ A;  1A62 A;  1GL9 B; 
#chains in the Genus database with same CATH homology
 1JEQ A;  2RNO A;  1V66 A;  1ZBH A;  2RNN A;  2KW9 A;  2KVD A;  4UZW A;  4BIT A;  2JVW A;  2KVE A;  2KVU A;  1JJR A;  1H1J S;  2WQG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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