1YZEA

Crystal structure of the n-terminal domain of usp7/hausp.
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
139
structure length
101
Chain Sequence
WRSEATFQFTVERFVLSPPCFVRNLPWKIMVMPRVGFFLQCNAESDSTSWSCHAQAVLKIIFSRRISHLFFHKENDWGFSNFMAWKVTFEVFVQADAPHGV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
source organism Homo sapiens
publication title Structure of the p53 binding domain of HAUSP/USP7 bound to Epstein-Barr nuclear antigen 1 implications for EBV-mediated immortalization.
pubmed doi rcsb
molecule keywords Ubiquitin carboxyl-terminal hydrolase 7
total genus 14
structure length 101
sequence length 139
chains with identical sequence B, C
ec nomenclature ec 3.4.19.12: Ubiquitinyl hydrolase 1.
pdb deposition date 2005-02-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00917 MATH MATH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.210.10 Mainly Beta Sandwich Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A 1yzeA00
2CR2A 4YSIA 2FOJA 4CA1A 1D00A 4GHUA 2F1WA 2F1YA 3HSVA 2FOOA 2XXNA 1CA9A 1F3VB 4X3GA 1FLKA 3HQIA 3HQHA 4C9ZA 1LB4A 2F1ZA 1CA4A 3MQSC 1D0AA 1QSCA 2AN6A 3HU6A 1KZZA 4GWMA 4M4EA 4Z8MA 1LB5A 2GKWA 4JJQA 4KG9A 1K2FA 1CZYA 4I7DA 3HQMA 3HQLA 1L0AA 4I7CA 3IVBA 1YY6A 1FLLA 2F1XA 3MQRA 5H9MA 1D01A 2A25A 3IVVA 3ZJBA 1YZEA 1LB6A 4K8UA 1ZMSA 4I7BA 1RF3A 4O1VA 1D0JA 5E1TA 1CZZA 2FOPA 4GWNA 4GJHA 3IVQA
chains in the Genus database with same CATH superfamily
2CR2A 4YSIA 2FOJA 4CA1A 1D00A 4GHUA 2F1WA 2F1YA 3HSVA 2FOOA 2XXNA 1CA9A 1F3VB 4X3GA 1FLKA 3HQIA 3HQHA 4C9ZA 1LB4A 2F1ZA 1CA4A 3MQSC 1D0AA 1QSCA 2AN6A 3HU6A 1KZZA 4GWMA 4M4EA 4Z8MA 1LB5A 2GKWA 4JJQA 4KG9A 1K2FA 1CZYA 4I7DA 3HQMA 3HQLA 1L0AA 4I7CA 3IVBA 1YY6A 1FLLA 2F1XA 3MQRA 5H9MA 1D01A 2A25A 3IVVA 3ZJBA 1YZEA 1LB6A 4K8UA 1ZMSA 4I7BA 1RF3A 4O1VA 1D0JA 5E1TA 1CZZA 2FOPA 4GWNA 4GJHA 3IVQA
chains in the Genus database with same CATH topology
2CR2A 4YSIA 2FOJA 4CA1A 1D00A 4GHUA 2F1WA 2F1YA 3HSVA 2FOOA 2XXNA 1CA9A 1F3VB 4X3GA 1FLKA 3HQIA 3HQHA 4C9ZA 1LB4A 2F1ZA 1CA4A 3MQSC 1D0AA 1QSCA 2AN6A 3HU6A 1KZZA 4GWMA 4M4EA 4Z8MA 1LB5A 2GKWA 4JJQA 4KG9A 1K2FA 1CZYA 4I7DA 3HQMA 3HQLA 1L0AA 4I7CA 3IVBA 1YY6A 1FLLA 2F1XA 3MQRA 5H9MA 1D01A 2A25A 3IVVA 3ZJBA 1YZEA 1LB6A 4K8UA 1ZMSA 4I7BA 1RF3A 4O1VA 1D0JA 5E1TA 1CZZA 2FOPA 4GWNA 4GJHA 3IVQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2CR2 A;  4YSI A;  2FOJ A;  4CA1 A;  1D00 A;  4GHU A;  2F1W A;  2F1Y A;  3HSV A;  2FOO A;  2XXN A;  1CA9 A;  1F3V B;  4X3G A;  1FLK A;  3HQI A;  3HQH A;  4C9Z A;  1LB4 A;  2F1Z A;  1CA4 A;  3MQS C;  1D0A A;  1QSC A;  2AN6 A;  3HU6 A;  1KZZ A;  4GWM A;  4M4E A;  4Z8M A;  1LB5 A;  2GKW A;  4JJQ A;  4KG9 A;  1K2F A;  1CZY A;  4I7D A;  3HQM A;  3HQL A;  1L0A A;  4I7C A;  3IVB A;  1YY6 A;  1FLL A;  2F1X A;  3MQR A;  5H9M A;  1D01 A;  2A25 A;  3IVV A;  3ZJB A;  1YZE A;  1LB6 A;  4K8U A;  1ZMS A;  4I7B A;  1RF3 A;  4O1V A;  1D0J A;  5E1T A;  1CZZ A;  2FOP A;  4GWN A;  4GJH A;  3IVQ A; 
#chains in the Genus database with same CATH topology
 2CR2 A;  4YSI A;  2FOJ A;  4CA1 A;  1D00 A;  4GHU A;  2F1W A;  2F1Y A;  3HSV A;  2FOO A;  2XXN A;  1CA9 A;  1F3V B;  4X3G A;  1FLK A;  3HQI A;  3HQH A;  4C9Z A;  1LB4 A;  2F1Z A;  1CA4 A;  3MQS C;  1D0A A;  1QSC A;  2AN6 A;  3HU6 A;  1KZZ A;  4GWM A;  4M4E A;  4Z8M A;  1LB5 A;  2GKW A;  4JJQ A;  4KG9 A;  1K2F A;  1CZY A;  4I7D A;  3HQM A;  3HQL A;  1L0A A;  4I7C A;  3IVB A;  1YY6 A;  1FLL A;  2F1X A;  3MQR A;  5H9M A;  1D01 A;  2A25 A;  3IVV A;  3ZJB A;  1YZE A;  1LB6 A;  4K8U A;  1ZMS A;  4I7B A;  1RF3 A;  4O1V A;  1D0J A;  5E1T A;  1CZZ A;  2FOP A;  4GWN A;  4GJH A;  3IVQ A; 
#chains in the Genus database with same CATH homology
 2CR2 A;  4YSI A;  2FOJ A;  4CA1 A;  1D00 A;  4GHU A;  2F1W A;  2F1Y A;  3HSV A;  2FOO A;  2XXN A;  1CA9 A;  1F3V B;  4X3G A;  1FLK A;  3HQI A;  3HQH A;  4C9Z A;  1LB4 A;  2F1Z A;  1CA4 A;  3MQS C;  1D0A A;  1QSC A;  2AN6 A;  3HU6 A;  1KZZ A;  4GWM A;  4M4E A;  4Z8M A;  1LB5 A;  2GKW A;  4JJQ A;  4KG9 A;  1K2F A;  1CZY A;  4I7D A;  3HQM A;  3HQL A;  1L0A A;  4I7C A;  3IVB A;  1YY6 A;  1FLL A;  2F1X A;  3MQR A;  5H9M A;  1D01 A;  2A25 A;  3IVV A;  3ZJB A;  1YZE A;  1LB6 A;  4K8U A;  1ZMS A;  4I7B A;  1RF3 A;  4O1V A;  1D0J A;  5E1T A;  1CZZ A;  2FOP A;  4GWN A;  4GJH A;  3IVQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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