1YZEA

Crystal structure of the n-terminal domain of usp7/hausp.
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
139
structure length
101
Chain Sequence
WRSEATFQFTVERFVLSPPCFVRNLPWKIMVMPRVGFFLQCNAESDSTSWSCHAQAVLKIIFSRRISHLFFHKENDWGFSNFMAWKVTFEVFVQADAPHGV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the p53 binding domain of HAUSP/USP7 bound to Epstein-Barr nuclear antigen 1 implications for EBV-mediated immortalization.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Ubiquitin carboxyl-terminal hydrolase 7
total genus 14
structure length 101
sequence length 139
chains with identical sequence B, C
ec nomenclature ec 3.4.19.12: Ubiquitinyl hydrolase 1.
pdb deposition date 2005-02-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00917 MATH MATH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.210.10 Mainly Beta Sandwich Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A 1yzeA00
2F1XA 2A25A 2F1WA 4Z8MA 2FOOA 2F1ZA 1QSCA 4YSIA 3MQSC 4O1VA 1CA9A 3IVQA 2FOPA 3MQRA 4GHUA 3HSVA 2XXNA 3IVVA 5H9MA 3IVBA 1CZYA 1K2FA 1CZZA 1LB4A 1RF3A 4I7DA 4X3GA 4CA1A 1FLLA 4GWMA 2F1YA 2GKWA 4C9ZA 4M4EA 1D01A 3HQMA 4KG9A 3HU6A 3HQLA 1CA4A 2FOJA 1ZMSA 4JJQA 4I7CA 2AN6A 1D0JA 1D00A 4GJHA 4GWNA 4I7BA 1D0AA 1FLKA 1YZEA 5E1TA 3ZJBA 3HQIA 1LB6A 4K8UA 1L0AA 1YY6A 1KZZA 1F3VB 2CR2A 1LB5A 3HQHA
chains in the Genus database with same CATH superfamily
2F1XA 2A25A 2F1WA 4Z8MA 2FOOA 2F1ZA 1QSCA 4YSIA 3MQSC 4O1VA 1CA9A 3IVQA 2FOPA 3MQRA 4GHUA 3HSVA 2XXNA 3IVVA 5H9MA 3IVBA 1CZYA 1K2FA 1CZZA 1LB4A 1RF3A 4I7DA 4X3GA 4CA1A 1FLLA 4GWMA 2F1YA 2GKWA 4C9ZA 4M4EA 1D01A 3HQMA 4KG9A 3HU6A 3HQLA 1CA4A 2FOJA 1ZMSA 4JJQA 4I7CA 2AN6A 1D0JA 1D00A 4GJHA 4GWNA 4I7BA 1D0AA 1FLKA 1YZEA 5E1TA 3ZJBA 3HQIA 1LB6A 4K8UA 1L0AA 1YY6A 1KZZA 1F3VB 2CR2A 1LB5A 3HQHA
chains in the Genus database with same CATH topology
2F1XA 2A25A 2F1WA 4Z8MA 2FOOA 2F1ZA 1QSCA 4YSIA 3MQSC 4O1VA 1CA9A 3IVQA 2FOPA 3MQRA 4GHUA 3HSVA 2XXNA 3IVVA 5H9MA 3IVBA 1CZYA 1K2FA 1CZZA 1LB4A 1RF3A 4I7DA 4X3GA 4CA1A 1FLLA 4GWMA 2F1YA 2GKWA 4C9ZA 4M4EA 1D01A 3HQMA 4KG9A 3HU6A 3HQLA 1CA4A 2FOJA 1ZMSA 4JJQA 4I7CA 2AN6A 1D0JA 1D00A 4GJHA 4GWNA 4I7BA 1D0AA 1FLKA 1YZEA 5E1TA 3ZJBA 3HQIA 1LB6A 4K8UA 1L0AA 1YY6A 1KZZA 1F3VB 2CR2A 1LB5A 3HQHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2F1X A;  2A25 A;  2F1W A;  4Z8M A;  2FOO A;  2F1Z A;  1QSC A;  4YSI A;  3MQS C;  4O1V A;  1CA9 A;  3IVQ A;  2FOP A;  3MQR A;  4GHU A;  3HSV A;  2XXN A;  3IVV A;  5H9M A;  3IVB A;  1CZY A;  1K2F A;  1CZZ A;  1LB4 A;  1RF3 A;  4I7D A;  4X3G A;  4CA1 A;  1FLL A;  4GWM A;  2F1Y A;  2GKW A;  4C9Z A;  4M4E A;  1D01 A;  3HQM A;  4KG9 A;  3HU6 A;  3HQL A;  1CA4 A;  2FOJ A;  1ZMS A;  4JJQ A;  4I7C A;  2AN6 A;  1D0J A;  1D00 A;  4GJH A;  4GWN A;  4I7B A;  1D0A A;  1FLK A;  1YZE A;  5E1T A;  3ZJB A;  3HQI A;  1LB6 A;  4K8U A;  1L0A A;  1YY6 A;  1KZZ A;  1F3V B;  2CR2 A;  1LB5 A;  3HQH A; 
#chains in the Genus database with same CATH topology
 2F1X A;  2A25 A;  2F1W A;  4Z8M A;  2FOO A;  2F1Z A;  1QSC A;  4YSI A;  3MQS C;  4O1V A;  1CA9 A;  3IVQ A;  2FOP A;  3MQR A;  4GHU A;  3HSV A;  2XXN A;  3IVV A;  5H9M A;  3IVB A;  1CZY A;  1K2F A;  1CZZ A;  1LB4 A;  1RF3 A;  4I7D A;  4X3G A;  4CA1 A;  1FLL A;  4GWM A;  2F1Y A;  2GKW A;  4C9Z A;  4M4E A;  1D01 A;  3HQM A;  4KG9 A;  3HU6 A;  3HQL A;  1CA4 A;  2FOJ A;  1ZMS A;  4JJQ A;  4I7C A;  2AN6 A;  1D0J A;  1D00 A;  4GJH A;  4GWN A;  4I7B A;  1D0A A;  1FLK A;  1YZE A;  5E1T A;  3ZJB A;  3HQI A;  1LB6 A;  4K8U A;  1L0A A;  1YY6 A;  1KZZ A;  1F3V B;  2CR2 A;  1LB5 A;  3HQH A; 
#chains in the Genus database with same CATH homology
 2F1X A;  2A25 A;  2F1W A;  4Z8M A;  2FOO A;  2F1Z A;  1QSC A;  4YSI A;  3MQS C;  4O1V A;  1CA9 A;  3IVQ A;  2FOP A;  3MQR A;  4GHU A;  3HSV A;  2XXN A;  3IVV A;  5H9M A;  3IVB A;  1CZY A;  1K2F A;  1CZZ A;  1LB4 A;  1RF3 A;  4I7D A;  4X3G A;  4CA1 A;  1FLL A;  4GWM A;  2F1Y A;  2GKW A;  4C9Z A;  4M4E A;  1D01 A;  3HQM A;  4KG9 A;  3HU6 A;  3HQL A;  1CA4 A;  2FOJ A;  1ZMS A;  4JJQ A;  4I7C A;  2AN6 A;  1D0J A;  1D00 A;  4GJH A;  4GWN A;  4I7B A;  1D0A A;  1FLK A;  1YZE A;  5E1T A;  3ZJB A;  3HQI A;  1LB6 A;  4K8U A;  1L0A A;  1YY6 A;  1KZZ A;  1F3V B;  2CR2 A;  1LB5 A;  3HQH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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