1CA9A

Structure of tnf receptor associated factor 2 in complex with a peptide from tnf-r2
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
191
structure length
191
Chain Sequence
QDKIEALSSKVQQLERSIGLKDLAMADLEQKVLEMEASTYDGVFIWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQNNREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDLTGL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis for self-association and receptor recognition of human TRAF2.
pubmed doi rcsb
molecule tags Tnf signaling
source organism Homo sapiens
molecule keywords PROTEIN (TNF RECEPTOR ASSOCIATED FACTOR 2)
total genus 47
structure length 191
sequence length 191
chains with identical sequence B, C, D, E, F
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 1999-02-25
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.210.10 Mainly Beta Sandwich Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A 1ca9A00
1D01A 3MQSC 4GHUA 1FLKA 4JJQA 1LB5A 4O1VA 1RF3A 3IVBA 1D0JA 1FLLA 1D0AA 1F3VB 1KZZA 2F1ZA 3HU6A 3HSVA 1YY6A 3IVVA 4GWMA 1CZZA 1L0AA 4K8UA 2AN6A 2FOJA 1YZEA 1K2FA 5E1TA 2XXNA 4GWNA 4I7DA 1D00A 4I7BA 4I7CA 5H9MA 2FOPA 1CZYA 1LB4A 4X3GA 2A25A 1LB6A 4M4EA 2F1XA 4Z8MA 2F1WA 1ZMSA 3IVQA 1QSCA 4C9ZA 3HQMA 3HQHA 3ZJBA 4GJHA 4KG9A 4CA1A 2FOOA 2GKWA 4YSIA 3HQLA 1CA4A 3MQRA 2F1YA 3HQIA 1CA9A 2CR2A
chains in the Genus database with same CATH superfamily
1D01A 3MQSC 4GHUA 1FLKA 4JJQA 1LB5A 4O1VA 1RF3A 3IVBA 1D0JA 1FLLA 1D0AA 1F3VB 1KZZA 2F1ZA 3HU6A 3HSVA 1YY6A 3IVVA 4GWMA 1CZZA 1L0AA 4K8UA 2AN6A 2FOJA 1YZEA 1K2FA 5E1TA 2XXNA 4GWNA 4I7DA 1D00A 4I7BA 4I7CA 5H9MA 2FOPA 1CZYA 1LB4A 4X3GA 2A25A 1LB6A 4M4EA 2F1XA 4Z8MA 2F1WA 1ZMSA 3IVQA 1QSCA 4C9ZA 3HQMA 3HQHA 3ZJBA 4GJHA 4KG9A 4CA1A 2FOOA 2GKWA 4YSIA 3HQLA 1CA4A 3MQRA 2F1YA 3HQIA 1CA9A 2CR2A
chains in the Genus database with same CATH topology
1D01A 3MQSC 4GHUA 1FLKA 4JJQA 1LB5A 4O1VA 1RF3A 3IVBA 1D0JA 1FLLA 1D0AA 1F3VB 1KZZA 2F1ZA 3HU6A 3HSVA 1YY6A 3IVVA 4GWMA 1CZZA 1L0AA 4K8UA 2AN6A 2FOJA 1YZEA 1K2FA 5E1TA 2XXNA 4GWNA 4I7DA 1D00A 4I7BA 4I7CA 5H9MA 2FOPA 1CZYA 1LB4A 4X3GA 2A25A 1LB6A 4M4EA 2F1XA 4Z8MA 2F1WA 1ZMSA 3IVQA 1QSCA 4C9ZA 3HQMA 3HQHA 3ZJBA 4GJHA 4KG9A 4CA1A 2FOOA 2GKWA 4YSIA 3HQLA 1CA4A 3MQRA 2F1YA 3HQIA 1CA9A 2CR2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1D01 A;  3MQS C;  4GHU A;  1FLK A;  4JJQ A;  1LB5 A;  4O1V A;  1RF3 A;  3IVB A;  1D0J A;  1FLL A;  1D0A A;  1F3V B;  1KZZ A;  2F1Z A;  3HU6 A;  3HSV A;  1YY6 A;  3IVV A;  4GWM A;  1CZZ A;  1L0A A;  4K8U A;  2AN6 A;  2FOJ A;  1YZE A;  1K2F A;  5E1T A;  2XXN A;  4GWN A;  4I7D A;  1D00 A;  4I7B A;  4I7C A;  5H9M A;  2FOP A;  1CZY A;  1LB4 A;  4X3G A;  2A25 A;  1LB6 A;  4M4E A;  2F1X A;  4Z8M A;  2F1W A;  1ZMS A;  3IVQ A;  1QSC A;  4C9Z A;  3HQM A;  3HQH A;  3ZJB A;  4GJH A;  4KG9 A;  4CA1 A;  2FOO A;  2GKW A;  4YSI A;  3HQL A;  1CA4 A;  3MQR A;  2F1Y A;  3HQI A;  1CA9 A;  2CR2 A; 
#chains in the Genus database with same CATH topology
 1D01 A;  3MQS C;  4GHU A;  1FLK A;  4JJQ A;  1LB5 A;  4O1V A;  1RF3 A;  3IVB A;  1D0J A;  1FLL A;  1D0A A;  1F3V B;  1KZZ A;  2F1Z A;  3HU6 A;  3HSV A;  1YY6 A;  3IVV A;  4GWM A;  1CZZ A;  1L0A A;  4K8U A;  2AN6 A;  2FOJ A;  1YZE A;  1K2F A;  5E1T A;  2XXN A;  4GWN A;  4I7D A;  1D00 A;  4I7B A;  4I7C A;  5H9M A;  2FOP A;  1CZY A;  1LB4 A;  4X3G A;  2A25 A;  1LB6 A;  4M4E A;  2F1X A;  4Z8M A;  2F1W A;  1ZMS A;  3IVQ A;  1QSC A;  4C9Z A;  3HQM A;  3HQH A;  3ZJB A;  4GJH A;  4KG9 A;  4CA1 A;  2FOO A;  2GKW A;  4YSI A;  3HQL A;  1CA4 A;  3MQR A;  2F1Y A;  3HQI A;  1CA9 A;  2CR2 A; 
#chains in the Genus database with same CATH homology
 1D01 A;  3MQS C;  4GHU A;  1FLK A;  4JJQ A;  1LB5 A;  4O1V A;  1RF3 A;  3IVB A;  1D0J A;  1FLL A;  1D0A A;  1F3V B;  1KZZ A;  2F1Z A;  3HU6 A;  3HSV A;  1YY6 A;  3IVV A;  4GWM A;  1CZZ A;  1L0A A;  4K8U A;  2AN6 A;  2FOJ A;  1YZE A;  1K2F A;  5E1T A;  2XXN A;  4GWN A;  4I7D A;  1D00 A;  4I7B A;  4I7C A;  5H9M A;  2FOP A;  1CZY A;  1LB4 A;  4X3G A;  2A25 A;  1LB6 A;  4M4E A;  2F1X A;  4Z8M A;  2F1W A;  1ZMS A;  3IVQ A;  1QSC A;  4C9Z A;  3HQM A;  3HQH A;  3ZJB A;  4GJH A;  4KG9 A;  4CA1 A;  2FOO A;  2GKW A;  4YSI A;  3HQL A;  1CA4 A;  3MQR A;  2F1Y A;  3HQI A;  1CA9 A;  2CR2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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