1LB4A

Traf6 apo structure
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
159
structure length
155
Chain Sequence
QCNGIYIWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTAQRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPELLAFQRPTIKGFGYVTFMHLEALRQRTFIKDDTLLVRCEVSTRFDLE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Distinct molecular mechanism for initiating TRAF6 signalling.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords TNF receptor-associated factor 6
total genus 27
structure length 155
sequence length 159
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2002-04-02
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.210.10 Mainly Beta Sandwich Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A 1lb4A00
4JJQA 3MQRA 4X3GA 5H9MA 1D01A 1RF3A 4C9ZA 1ZMSA 4GWMA 1FLKA 1CZZA 4K8UA 1QSCA 2CR2A 1F3VB 1YY6A 3HQHA 2F1WA 4KG9A 1KZZA 3IVVA 4Z8MA 1FLLA 1D0AA 4I7DA 1LB6A 2GKWA 3HQIA 1CA9A 3IVQA 4CA1A 1YZEA 2XXNA 5E1TA 4O1VA 1D00A 1CZYA 2A25A 2F1YA 2FOPA 3HQLA 3IVBA 4GHUA 1D0JA 1L0AA 3ZJBA 3HSVA 2F1XA 1LB5A 1LB4A 3HU6A 4YSIA 4I7BA 1K2FA 2FOJA 1CA4A 2FOOA 3HQMA 2F1ZA 4I7CA 4GWNA 2AN6A 3MQSC 4M4EA 4GJHA
chains in the Genus database with same CATH superfamily
4JJQA 3MQRA 4X3GA 5H9MA 1D01A 1RF3A 4C9ZA 1ZMSA 4GWMA 1FLKA 1CZZA 4K8UA 1QSCA 2CR2A 1F3VB 1YY6A 3HQHA 2F1WA 4KG9A 1KZZA 3IVVA 4Z8MA 1FLLA 1D0AA 4I7DA 1LB6A 2GKWA 3HQIA 1CA9A 3IVQA 4CA1A 1YZEA 2XXNA 5E1TA 4O1VA 1D00A 1CZYA 2A25A 2F1YA 2FOPA 3HQLA 3IVBA 4GHUA 1D0JA 1L0AA 3ZJBA 3HSVA 2F1XA 1LB5A 1LB4A 3HU6A 4YSIA 4I7BA 1K2FA 2FOJA 1CA4A 2FOOA 3HQMA 2F1ZA 4I7CA 4GWNA 2AN6A 3MQSC 4M4EA 4GJHA
chains in the Genus database with same CATH topology
4JJQA 3MQRA 4X3GA 5H9MA 1D01A 1RF3A 4C9ZA 1ZMSA 4GWMA 1FLKA 1CZZA 4K8UA 1QSCA 2CR2A 1F3VB 1YY6A 3HQHA 2F1WA 4KG9A 1KZZA 3IVVA 4Z8MA 1FLLA 1D0AA 4I7DA 1LB6A 2GKWA 3HQIA 1CA9A 3IVQA 4CA1A 1YZEA 2XXNA 5E1TA 4O1VA 1D00A 1CZYA 2A25A 2F1YA 2FOPA 3HQLA 3IVBA 4GHUA 1D0JA 1L0AA 3ZJBA 3HSVA 2F1XA 1LB5A 1LB4A 3HU6A 4YSIA 4I7BA 1K2FA 2FOJA 1CA4A 2FOOA 3HQMA 2F1ZA 4I7CA 4GWNA 2AN6A 3MQSC 4M4EA 4GJHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4JJQ A;  3MQR A;  4X3G A;  5H9M A;  1D01 A;  1RF3 A;  4C9Z A;  1ZMS A;  4GWM A;  1FLK A;  1CZZ A;  4K8U A;  1QSC A;  2CR2 A;  1F3V B;  1YY6 A;  3HQH A;  2F1W A;  4KG9 A;  1KZZ A;  3IVV A;  4Z8M A;  1FLL A;  1D0A A;  4I7D A;  1LB6 A;  2GKW A;  3HQI A;  1CA9 A;  3IVQ A;  4CA1 A;  1YZE A;  2XXN A;  5E1T A;  4O1V A;  1D00 A;  1CZY A;  2A25 A;  2F1Y A;  2FOP A;  3HQL A;  3IVB A;  4GHU A;  1D0J A;  1L0A A;  3ZJB A;  3HSV A;  2F1X A;  1LB5 A;  1LB4 A;  3HU6 A;  4YSI A;  4I7B A;  1K2F A;  2FOJ A;  1CA4 A;  2FOO A;  3HQM A;  2F1Z A;  4I7C A;  4GWN A;  2AN6 A;  3MQS C;  4M4E A;  4GJH A; 
#chains in the Genus database with same CATH topology
 4JJQ A;  3MQR A;  4X3G A;  5H9M A;  1D01 A;  1RF3 A;  4C9Z A;  1ZMS A;  4GWM A;  1FLK A;  1CZZ A;  4K8U A;  1QSC A;  2CR2 A;  1F3V B;  1YY6 A;  3HQH A;  2F1W A;  4KG9 A;  1KZZ A;  3IVV A;  4Z8M A;  1FLL A;  1D0A A;  4I7D A;  1LB6 A;  2GKW A;  3HQI A;  1CA9 A;  3IVQ A;  4CA1 A;  1YZE A;  2XXN A;  5E1T A;  4O1V A;  1D00 A;  1CZY A;  2A25 A;  2F1Y A;  2FOP A;  3HQL A;  3IVB A;  4GHU A;  1D0J A;  1L0A A;  3ZJB A;  3HSV A;  2F1X A;  1LB5 A;  1LB4 A;  3HU6 A;  4YSI A;  4I7B A;  1K2F A;  2FOJ A;  1CA4 A;  2FOO A;  3HQM A;  2F1Z A;  4I7C A;  4GWN A;  2AN6 A;  3MQS C;  4M4E A;  4GJH A; 
#chains in the Genus database with same CATH homology
 4JJQ A;  3MQR A;  4X3G A;  5H9M A;  1D01 A;  1RF3 A;  4C9Z A;  1ZMS A;  4GWM A;  1FLK A;  1CZZ A;  4K8U A;  1QSC A;  2CR2 A;  1F3V B;  1YY6 A;  3HQH A;  2F1W A;  4KG9 A;  1KZZ A;  3IVV A;  4Z8M A;  1FLL A;  1D0A A;  4I7D A;  1LB6 A;  2GKW A;  3HQI A;  1CA9 A;  3IVQ A;  4CA1 A;  1YZE A;  2XXN A;  5E1T A;  4O1V A;  1D00 A;  1CZY A;  2A25 A;  2F1Y A;  2FOP A;  3HQL A;  3IVB A;  4GHU A;  1D0J A;  1L0A A;  3ZJB A;  3HSV A;  2F1X A;  1LB5 A;  1LB4 A;  3HU6 A;  4YSI A;  4I7B A;  1K2F A;  2FOJ A;  1CA4 A;  2FOO A;  3HQM A;  2F1Z A;  4I7C A;  4GWN A;  2AN6 A;  3MQS C;  4M4E A;  4GJH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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