1LB6A

Traf6-cd40 complex
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
155
structure length
155
Chain Sequence
QQCNGIYIWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTAQRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPELLAFQRPTIPRNPKGFGYVTFMHLEALRQRTFIKDDTLLVRCEVST
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Distinct molecular mechanism for initiating TRAF6 signalling.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords TNF receptor-associated factor 6
total genus 27
structure length 155
sequence length 155
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2002-04-02
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.210.10 Mainly Beta Sandwich Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A 1lb6A00
2XXNA 3HQHA 4JJQA 2A25A 1CA9A 1D00A 1LB4A 1YZEA 2F1WA 2F1ZA 3HQLA 1FLKA 2GKWA 3HQIA 3HU6A 3MQSC 5H9MA 3MQRA 1YY6A 2AN6A 3HQMA 3IVVA 3IVQA 4Z8MA 1CZYA 1D01A 2F1XA 1ZMSA 4O1VA 4X3GA 1CZZA 4GJHA 4M4EA 1LB5A 1D0JA 4I7DA 4K8UA 4GWMA 1KZZA 4KG9A 2CR2A 2F1YA 2FOJA 2FOOA 4YSIA 4C9ZA 5E1TA 4I7CA 3IVBA 4I7BA 4CA1A 1CA4A 1K2FA 1RF3A 1F3VB 1FLLA 1D0AA 1QSCA 2FOPA 1LB6A 1L0AA 4GWNA 3HSVA 3ZJBA 4GHUA
chains in the Genus database with same CATH superfamily
2XXNA 3HQHA 4JJQA 2A25A 1CA9A 1D00A 1LB4A 1YZEA 2F1WA 2F1ZA 3HQLA 1FLKA 2GKWA 3HQIA 3HU6A 3MQSC 5H9MA 3MQRA 1YY6A 2AN6A 3HQMA 3IVVA 3IVQA 4Z8MA 1CZYA 1D01A 2F1XA 1ZMSA 4O1VA 4X3GA 1CZZA 4GJHA 4M4EA 1LB5A 1D0JA 4I7DA 4K8UA 4GWMA 1KZZA 4KG9A 2CR2A 2F1YA 2FOJA 2FOOA 4YSIA 4C9ZA 5E1TA 4I7CA 3IVBA 4I7BA 4CA1A 1CA4A 1K2FA 1RF3A 1F3VB 1FLLA 1D0AA 1QSCA 2FOPA 1LB6A 1L0AA 4GWNA 3HSVA 3ZJBA 4GHUA
chains in the Genus database with same CATH topology
2XXNA 3HQHA 4JJQA 2A25A 1CA9A 1D00A 1LB4A 1YZEA 2F1WA 2F1ZA 3HQLA 1FLKA 2GKWA 3HQIA 3HU6A 3MQSC 5H9MA 3MQRA 1YY6A 2AN6A 3HQMA 3IVVA 3IVQA 4Z8MA 1CZYA 1D01A 2F1XA 1ZMSA 4O1VA 4X3GA 1CZZA 4GJHA 4M4EA 1LB5A 1D0JA 4I7DA 4K8UA 4GWMA 1KZZA 4KG9A 2CR2A 2F1YA 2FOJA 2FOOA 4YSIA 4C9ZA 5E1TA 4I7CA 3IVBA 4I7BA 4CA1A 1CA4A 1K2FA 1RF3A 1F3VB 1FLLA 1D0AA 1QSCA 2FOPA 1LB6A 1L0AA 4GWNA 3HSVA 3ZJBA 4GHUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XXN A;  3HQH A;  4JJQ A;  2A25 A;  1CA9 A;  1D00 A;  1LB4 A;  1YZE A;  2F1W A;  2F1Z A;  3HQL A;  1FLK A;  2GKW A;  3HQI A;  3HU6 A;  3MQS C;  5H9M A;  3MQR A;  1YY6 A;  2AN6 A;  3HQM A;  3IVV A;  3IVQ A;  4Z8M A;  1CZY A;  1D01 A;  2F1X A;  1ZMS A;  4O1V A;  4X3G A;  1CZZ A;  4GJH A;  4M4E A;  1LB5 A;  1D0J A;  4I7D A;  4K8U A;  4GWM A;  1KZZ A;  4KG9 A;  2CR2 A;  2F1Y A;  2FOJ A;  2FOO A;  4YSI A;  4C9Z A;  5E1T A;  4I7C A;  3IVB A;  4I7B A;  4CA1 A;  1CA4 A;  1K2F A;  1RF3 A;  1F3V B;  1FLL A;  1D0A A;  1QSC A;  2FOP A;  1LB6 A;  1L0A A;  4GWN A;  3HSV A;  3ZJB A;  4GHU A; 
#chains in the Genus database with same CATH topology
 2XXN A;  3HQH A;  4JJQ A;  2A25 A;  1CA9 A;  1D00 A;  1LB4 A;  1YZE A;  2F1W A;  2F1Z A;  3HQL A;  1FLK A;  2GKW A;  3HQI A;  3HU6 A;  3MQS C;  5H9M A;  3MQR A;  1YY6 A;  2AN6 A;  3HQM A;  3IVV A;  3IVQ A;  4Z8M A;  1CZY A;  1D01 A;  2F1X A;  1ZMS A;  4O1V A;  4X3G A;  1CZZ A;  4GJH A;  4M4E A;  1LB5 A;  1D0J A;  4I7D A;  4K8U A;  4GWM A;  1KZZ A;  4KG9 A;  2CR2 A;  2F1Y A;  2FOJ A;  2FOO A;  4YSI A;  4C9Z A;  5E1T A;  4I7C A;  3IVB A;  4I7B A;  4CA1 A;  1CA4 A;  1K2F A;  1RF3 A;  1F3V B;  1FLL A;  1D0A A;  1QSC A;  2FOP A;  1LB6 A;  1L0A A;  4GWN A;  3HSV A;  3ZJB A;  4GHU A; 
#chains in the Genus database with same CATH homology
 2XXN A;  3HQH A;  4JJQ A;  2A25 A;  1CA9 A;  1D00 A;  1LB4 A;  1YZE A;  2F1W A;  2F1Z A;  3HQL A;  1FLK A;  2GKW A;  3HQI A;  3HU6 A;  3MQS C;  5H9M A;  3MQR A;  1YY6 A;  2AN6 A;  3HQM A;  3IVV A;  3IVQ A;  4Z8M A;  1CZY A;  1D01 A;  2F1X A;  1ZMS A;  4O1V A;  4X3G A;  1CZZ A;  4GJH A;  4M4E A;  1LB5 A;  1D0J A;  4I7D A;  4K8U A;  4GWM A;  1KZZ A;  4KG9 A;  2CR2 A;  2F1Y A;  2FOJ A;  2FOO A;  4YSI A;  4C9Z A;  5E1T A;  4I7C A;  3IVB A;  4I7B A;  4CA1 A;  1CA4 A;  1K2F A;  1RF3 A;  1F3V B;  1FLL A;  1D0A A;  1QSC A;  2FOP A;  1LB6 A;  1L0A A;  4GWN A;  3HSV A;  3ZJB A;  4GHU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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