1QSCA

Crystal structure of the traf domain of traf2 in a complex with a peptide from the cd40 receptor
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
179
structure length
179
Chain Sequence
QLERSIGLKDLAMADLEQKVLEMEASTYDGVFIWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQNNREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDLTGL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystallographic analysis of CD40 recognition and signaling by human TRAF2.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords TNF RECEPTOR ASSOCIATED FACTOR 2
total genus 36
structure length 179
sequence length 179
chains with identical sequence B, C
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 1999-06-20
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.210.10 Mainly Beta Sandwich Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A 1qscA00
1FLKA 4X3GA 3MQSC 4YSIA 1K2FA 3HU6A 4C9ZA 4I7DA 1CA4A 1D01A 1QSCA 2A25A 2FOPA 2CR2A 3IVVA 1LB4A 3ZJBA 1ZMSA 1D00A 2FOOA 4K8UA 2AN6A 1LB5A 2GKWA 3HQMA 4KG9A 3HQHA 4O1VA 2FOJA 1D0AA 1D0JA 2F1YA 1KZZA 4GHUA 4I7BA 3IVBA 4CA1A 4JJQA 1CZYA 4I7CA 1LB6A 1CA9A 2F1XA 2F1WA 4Z8MA 1YY6A 4M4EA 5E1TA 4GWNA 1L0AA 3HQLA 2F1ZA 1F3VB 2XXNA 1CZZA 3HQIA 3HSVA 4GJHA 4GWMA 3IVQA 5H9MA 1RF3A 3MQRA 1FLLA 1YZEA
chains in the Genus database with same CATH superfamily
1FLKA 4X3GA 3MQSC 4YSIA 1K2FA 3HU6A 4C9ZA 4I7DA 1CA4A 1D01A 1QSCA 2A25A 2FOPA 2CR2A 3IVVA 1LB4A 3ZJBA 1ZMSA 1D00A 2FOOA 4K8UA 2AN6A 1LB5A 2GKWA 3HQMA 4KG9A 3HQHA 4O1VA 2FOJA 1D0AA 1D0JA 2F1YA 1KZZA 4GHUA 4I7BA 3IVBA 4CA1A 4JJQA 1CZYA 4I7CA 1LB6A 1CA9A 2F1XA 2F1WA 4Z8MA 1YY6A 4M4EA 5E1TA 4GWNA 1L0AA 3HQLA 2F1ZA 1F3VB 2XXNA 1CZZA 3HQIA 3HSVA 4GJHA 4GWMA 3IVQA 5H9MA 1RF3A 3MQRA 1FLLA 1YZEA
chains in the Genus database with same CATH topology
1FLKA 4X3GA 3MQSC 4YSIA 1K2FA 3HU6A 4C9ZA 4I7DA 1CA4A 1D01A 1QSCA 2A25A 2FOPA 2CR2A 3IVVA 1LB4A 3ZJBA 1ZMSA 1D00A 2FOOA 4K8UA 2AN6A 1LB5A 2GKWA 3HQMA 4KG9A 3HQHA 4O1VA 2FOJA 1D0AA 1D0JA 2F1YA 1KZZA 4GHUA 4I7BA 3IVBA 4CA1A 4JJQA 1CZYA 4I7CA 1LB6A 1CA9A 2F1XA 2F1WA 4Z8MA 1YY6A 4M4EA 5E1TA 4GWNA 1L0AA 3HQLA 2F1ZA 1F3VB 2XXNA 1CZZA 3HQIA 3HSVA 4GJHA 4GWMA 3IVQA 5H9MA 1RF3A 3MQRA 1FLLA 1YZEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FLK A;  4X3G A;  3MQS C;  4YSI A;  1K2F A;  3HU6 A;  4C9Z A;  4I7D A;  1CA4 A;  1D01 A;  1QSC A;  2A25 A;  2FOP A;  2CR2 A;  3IVV A;  1LB4 A;  3ZJB A;  1ZMS A;  1D00 A;  2FOO A;  4K8U A;  2AN6 A;  1LB5 A;  2GKW A;  3HQM A;  4KG9 A;  3HQH A;  4O1V A;  2FOJ A;  1D0A A;  1D0J A;  2F1Y A;  1KZZ A;  4GHU A;  4I7B A;  3IVB A;  4CA1 A;  4JJQ A;  1CZY A;  4I7C A;  1LB6 A;  1CA9 A;  2F1X A;  2F1W A;  4Z8M A;  1YY6 A;  4M4E A;  5E1T A;  4GWN A;  1L0A A;  3HQL A;  2F1Z A;  1F3V B;  2XXN A;  1CZZ A;  3HQI A;  3HSV A;  4GJH A;  4GWM A;  3IVQ A;  5H9M A;  1RF3 A;  3MQR A;  1FLL A;  1YZE A; 
#chains in the Genus database with same CATH topology
 1FLK A;  4X3G A;  3MQS C;  4YSI A;  1K2F A;  3HU6 A;  4C9Z A;  4I7D A;  1CA4 A;  1D01 A;  1QSC A;  2A25 A;  2FOP A;  2CR2 A;  3IVV A;  1LB4 A;  3ZJB A;  1ZMS A;  1D00 A;  2FOO A;  4K8U A;  2AN6 A;  1LB5 A;  2GKW A;  3HQM A;  4KG9 A;  3HQH A;  4O1V A;  2FOJ A;  1D0A A;  1D0J A;  2F1Y A;  1KZZ A;  4GHU A;  4I7B A;  3IVB A;  4CA1 A;  4JJQ A;  1CZY A;  4I7C A;  1LB6 A;  1CA9 A;  2F1X A;  2F1W A;  4Z8M A;  1YY6 A;  4M4E A;  5E1T A;  4GWN A;  1L0A A;  3HQL A;  2F1Z A;  1F3V B;  2XXN A;  1CZZ A;  3HQI A;  3HSV A;  4GJH A;  4GWM A;  3IVQ A;  5H9M A;  1RF3 A;  3MQR A;  1FLL A;  1YZE A; 
#chains in the Genus database with same CATH homology
 1FLK A;  4X3G A;  3MQS C;  4YSI A;  1K2F A;  3HU6 A;  4C9Z A;  4I7D A;  1CA4 A;  1D01 A;  1QSC A;  2A25 A;  2FOP A;  2CR2 A;  3IVV A;  1LB4 A;  3ZJB A;  1ZMS A;  1D00 A;  2FOO A;  4K8U A;  2AN6 A;  1LB5 A;  2GKW A;  3HQM A;  4KG9 A;  3HQH A;  4O1V A;  2FOJ A;  1D0A A;  1D0J A;  2F1Y A;  1KZZ A;  4GHU A;  4I7B A;  3IVB A;  4CA1 A;  4JJQ A;  1CZY A;  4I7C A;  1LB6 A;  1CA9 A;  2F1X A;  2F1W A;  4Z8M A;  1YY6 A;  4M4E A;  5E1T A;  4GWN A;  1L0A A;  3HQL A;  2F1Z A;  1F3V B;  2XXN A;  1CZZ A;  3HQI A;  3HSV A;  4GJH A;  4GWM A;  3IVQ A;  5H9M A;  1RF3 A;  3MQR A;  1FLL A;  1YZE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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