2A5YA

Structure of a ced-4/ced-9 complex
Total Genus 56
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
sequence length
175
structure length
173
Chain Sequence
DGKINDWEEPRLDIEGFVVDYFTHRIRQNGMEWFGAPGLPSGVQPEHEMMRVMGTIFEKKHAENFETFSEQLLAVPRISFSLYQDVVRTVGNAQQSPMSYGRLIGLISFGGFVAAKMMESVELQGQVRNLFVYTSLFIKTRIRNNWKEHNRSWDDFMTLGKQMKEDYERAEAE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the CED-4-CED-9 complex provides insights into programmed cell death in Caenorhabditis elegans.
pubmed doi rcsb
molecule tags Apoptosis
source organism Caenorhabditis elegans
molecule keywords Apoptosis regulator ced-9
total genus 56
structure length 173
sequence length 175
ec nomenclature
pdb deposition date 2005-07-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00452 Bcl-2 Apoptosis regulator proteins, Bcl-2 family
A PF02180 BH4 Bcl-2 homology region 4
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.437.10 Mainly Alpha Orthogonal Bundle Apoptosis Regulator Bcl-x Blc2-like 2a5yA00
4BDUA 2XA0A 2JCNA 1R2GA 1YSGA 4OQ5A 4S0PA 2KBWA 2W3LA 4BD2A 5FDRA 4BD6A 4QNQA 5KU9A 3KJ2A 4WMRA 3I1HA 1OHUA 1GJHA 1PQ1A 2RODA 4ZIFA 4ZIHA 2PQKA 2MEJA 4ZBIA 3IHCA 5KTGA 1O0LA 3ILCA 3IHEA 1G5JA 2VOFA 1YSIA 2O2FA 4K5BC 1K3KA 1F16A 3BL2A 3IO9A 2A5YA 4U2UA 4B4SA 5JSBA 1Q59A 2XPXA 2IMSA 1G5MA 2B48A 4OYDA 4ZBFA 4S0OA 2NL9A 1AF3A 4YJ4A 3IHDA 3MQPA 2VOIA 3IIHA 1YSNA 4QVXA 4HW4A 4BPIA 5IF4A 2ABOA 3KJ0A 4G35A 5C3FA 4HW2A 3DVUA 1WSXA 5FDOA 1R2IA 2VM6A 2KUAA 4BD8A 2O2MA 2M5BA 4ZEQA 3QBRA 2ROCA 3CVAX 1YSWA 4U2VA 5C6HA 2WH6A 1ZY3A 2LR1A 3MK8A 4YK9A 4BD7A 2MHSA 2O2NA 1BXLA 1R2EA 2JM6B 5FMIA 1MK3A 1R2DA 5IEZA 3IIGA 2YV6A 1TY4A 2V6QA 2K7WA 4HW3A 1LXLA 1PQ0A 4MI8A 3KZ0A 2IMTA 1MAZA 4ZIEA 2BIDA 1R2HA 2O21A 3PK1A 2O22A 3WIXA 4BPJA 3D7VA 4ZIIA 2NLAA 4OQ6A 3KJ1A 2VOGA 2VOHA 1DDBA 5FC4A 4ZIGA 2BZWA 3WIYA 2ME8A
chains in the Genus database with same CATH superfamily
4BDUA 2XA0A 2JCNA 1R2GA 1YSGA 4OQ5A 4S0PA 4D2LA 2VVWA 2KBWA 2W3LA 4BD2A 5FDRA 4BD6A 4M0SA 4QNQA 5KU9A 3KJ2A 4WMRA 3I1HA 1OHUA 1GJHA 4BBDA 1PQ1A 2RODA 4ZIFA 4ZIHA 2PQKA 2MEJA 4ZBIA 4BBCA 4LQKA 3IHCA 5KTGA 1O0LA 3ILCA 3IHEA 1G5JA 2VOFA 1YSIA 2O2FA 4K5BC 1K3KA 1F16A 3BL2A 2A5YA 3IO9A 4U2UA 4B4SA 5JSBA 1Q59A 2XPXA 2IMSA 1G5MA 2B48A 4OYDA 4ZBFA 4S0OA 2NL9A 1AF3A 4YJ4A 3IHDA 2O42A 3MQPA 3JRVA 2VOIA 3IIHA 1YSNA 4QVXA 4HW4A 4BPIA 5IF4A 2ABOA 3KJ0A 4G35A 5C3FA 2VTYA 4HW2A 4BBBA 2VVYA 3DVUA 4UF3A 1WSXA 5FDOA 1R2IA 2VM6A 2KUAA 4BD8A 2O2MA 2M5BA 4ZEQA 3QBRA 2ROCA 3CVAX 2JBYA 1YSWA 2UXEA 4U2VA 5C6HA 2WH6A 1ZY3A 2LR1A 3MK8A 4YK9A 4BD7A 2MHSA 2O2NA 1BXLA 1R2EA 2JM6B 5FMIA 1MK3A 1R2DA 2I39A 5IEZA 3IIGA 2YV6A 1TY4A 4D2MA 2VVXA 2V6QA 2K36A 4UF1A 2K7WA 4UF2A 4HW3A 1LXLA 1PQ0A 4MI8A 3KZ0A 2IMTA 1MAZA 4ZIEA 2BIDA 1R2HA 2O21A 3PK1A 2O22A 2JBXA 3WIXA 4BPJA 3D7VA 4ZIIA 2NLAA 4OQ6A 3KJ1A 2VOGA 2VOHA 1DDBA 5FC4A 4ZIGA 2BZWA 3WIYA 2ME8A
chains in the Genus database with same CATH topology
4BDUA 2XA0A 2JCNA 1R2GA 1YSGA 4OQ5A 4S0PA 2KBWA 2W3LA 4BD2A 5FDRA 4BD6A 4QNQA 5KU9A 3KJ2A 4WMRA 3I1HA 1OHUA 1GJHA 1PQ1A 2RODA 4ZIFA 4ZIHA 2PQKA 2MEJA 4ZBIA 3IHCA 5KTGA 1O0LA 3ILCA 3IHEA 1G5JA 2VOFA 1YSIA 2O2FA 4K5BC 1K3KA 1F16A 3BL2A 3IO9A 2A5YA 4U2UA 4B4SA 5JSBA 1Q59A 2XPXA 2IMSA 1G5MA 2B48A 4OYDA 4ZBFA 4S0OA 2NL9A 1AF3A 4YJ4A 3IHDA 3MQPA 2VOIA 3IIHA 1YSNA 4QVXA 4HW4A 4BPIA 5IF4A 2ABOA 3KJ0A 4G35A 5C3FA 4HW2A 3DVUA 1WSXA 5FDOA 1R2IA 2VM6A 2KUAA 4BD8A 2O2MA 2M5BA 4ZEQA 3QBRA 2ROCA 3CVAX 1YSWA 4U2VA 5C6HA 2WH6A 1ZY3A 2LR1A 3MK8A 4YK9A 4BD7A 2MHSA 2O2NA 1BXLA 1R2EA 2JM6B 5FMIA 1MK3A 1R2DA 5IEZA 3IIGA 2YV6A 1TY4A 2V6QA 2K7WA 4HW3A 1LXLA 1PQ0A 4MI8A 3KZ0A 2IMTA 1MAZA 4ZIEA 2BIDA 1R2HA 2O21A 3PK1A 2O22A 3WIXA 4BPJA 3D7VA 4ZIIA 2NLAA 4OQ6A 3KJ1A 2VOGA 2VOHA 1DDBA 5FC4A 4ZIGA 2BZWA 3WIYA 2ME8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BDU A;  2XA0 A;  2JCN A;  1R2G A;  1YSG A;  4OQ5 A;  4S0P A;  2KBW A;  2W3L A;  4BD2 A;  5FDR A;  4BD6 A;  4QNQ A;  5KU9 A;  3KJ2 A;  4WMR A;  3I1H A;  1OHU A;  1GJH A;  1PQ1 A;  2ROD A;  4ZIF A;  4ZIH A;  2PQK A;  2MEJ A;  4ZBI A;  3IHC A;  5KTG A;  1O0L A;  3ILC A;  3IHE A;  1G5J A;  2VOF A;  1YSI A;  2O2F A;  4K5B C;  1K3K A;  1F16 A;  3BL2 A;  3IO9 A;  2A5Y A;  4U2U A;  4B4S A;  5JSB A;  1Q59 A;  2XPX A;  2IMS A;  1G5M A;  2B48 A;  4OYD A;  4ZBF A;  4S0O A;  2NL9 A;  1AF3 A;  4YJ4 A;  3IHD A;  3MQP A;  2VOI A;  3IIH A;  1YSN A;  4QVX A;  4HW4 A;  4BPI A;  5IF4 A;  2ABO A;  3KJ0 A;  4G35 A;  5C3F A;  4HW2 A;  3DVU A;  1WSX A;  5FDO A;  1R2I A;  2VM6 A;  2KUA A;  4BD8 A;  2O2M A;  2M5B A;  4ZEQ A;  3QBR A;  2ROC A;  3CVA X;  1YSW A;  4U2V A;  5C6H A;  2WH6 A;  1ZY3 A;  2LR1 A;  3MK8 A;  4YK9 A;  4BD7 A;  2MHS A;  2O2N A;  1BXL A;  1R2E A;  2JM6 B;  5FMI A;  1MK3 A;  1R2D A;  5IEZ A;  3IIG A;  2YV6 A;  1TY4 A;  2V6Q A;  2K7W A;  4HW3 A;  1LXL A;  1PQ0 A;  4MI8 A;  3KZ0 A;  2IMT A;  1MAZ A;  4ZIE A;  2BID A;  1R2H A;  2O21 A;  3PK1 A;  2O22 A;  3WIX A;  4BPJ A;  3D7V A;  4ZII A;  2NLA A;  4OQ6 A;  3KJ1 A;  2VOG A;  2VOH A;  1DDB A;  5FC4 A;  4ZIG A;  2BZW A;  3WIY A;  2ME8 A; 
#chains in the Genus database with same CATH topology
 4BDU A;  2XA0 A;  2JCN A;  1R2G A;  1YSG A;  4OQ5 A;  4S0P A;  4D2L A;  2VVW A;  2KBW A;  2W3L A;  4BD2 A;  5FDR A;  4BD6 A;  4M0S A;  4QNQ A;  5KU9 A;  3KJ2 A;  4WMR A;  3I1H A;  1OHU A;  1GJH A;  4BBD A;  1PQ1 A;  2ROD A;  4ZIF A;  4ZIH A;  2PQK A;  2MEJ A;  4ZBI A;  4BBC A;  4LQK A;  3IHC A;  5KTG A;  1O0L A;  3ILC A;  3IHE A;  1G5J A;  2VOF A;  1YSI A;  2O2F A;  4K5B C;  1K3K A;  1F16 A;  3BL2 A;  2A5Y A;  3IO9 A;  4U2U A;  4B4S A;  5JSB A;  1Q59 A;  2XPX A;  2IMS A;  1G5M A;  2B48 A;  4OYD A;  4ZBF A;  4S0O A;  2NL9 A;  1AF3 A;  4YJ4 A;  3IHD A;  2O42 A;  3MQP A;  3JRV A;  2VOI A;  3IIH A;  1YSN A;  4QVX A;  4HW4 A;  4BPI A;  5IF4 A;  2ABO A;  3KJ0 A;  4G35 A;  5C3F A;  2VTY A;  4HW2 A;  4BBB A;  2VVY A;  3DVU A;  4UF3 A;  1WSX A;  5FDO A;  1R2I A;  2VM6 A;  2KUA A;  4BD8 A;  2O2M A;  2M5B A;  4ZEQ A;  3QBR A;  2ROC A;  3CVA X;  2JBY A;  1YSW A;  2UXE A;  4U2V A;  5C6H A;  2WH6 A;  1ZY3 A;  2LR1 A;  3MK8 A;  4YK9 A;  4BD7 A;  2MHS A;  2O2N A;  1BXL A;  1R2E A;  2JM6 B;  5FMI A;  1MK3 A;  1R2D A;  2I39 A;  5IEZ A;  3IIG A;  2YV6 A;  1TY4 A;  4D2M A;  2VVX A;  2V6Q A;  2K36 A;  4UF1 A;  2K7W A;  4UF2 A;  4HW3 A;  1LXL A;  1PQ0 A;  4MI8 A;  3KZ0 A;  2IMT A;  1MAZ A;  4ZIE A;  2BID A;  1R2H A;  2O21 A;  3PK1 A;  2O22 A;  2JBX A;  3WIX A;  4BPJ A;  3D7V A;  4ZII A;  2NLA A;  4OQ6 A;  3KJ1 A;  2VOG A;  2VOH A;  1DDB A;  5FC4 A;  4ZIG A;  2BZW A;  3WIY A;  2ME8 A; 
#chains in the Genus database with same CATH homology
 4BDU A;  2XA0 A;  2JCN A;  1R2G A;  1YSG A;  4OQ5 A;  4S0P A;  2KBW A;  2W3L A;  4BD2 A;  5FDR A;  4BD6 A;  4QNQ A;  5KU9 A;  3KJ2 A;  4WMR A;  3I1H A;  1OHU A;  1GJH A;  1PQ1 A;  2ROD A;  4ZIF A;  4ZIH A;  2PQK A;  2MEJ A;  4ZBI A;  3IHC A;  5KTG A;  1O0L A;  3ILC A;  3IHE A;  1G5J A;  2VOF A;  1YSI A;  2O2F A;  4K5B C;  1K3K A;  1F16 A;  3BL2 A;  3IO9 A;  2A5Y A;  4U2U A;  4B4S A;  5JSB A;  1Q59 A;  2XPX A;  2IMS A;  1G5M A;  2B48 A;  4OYD A;  4ZBF A;  4S0O A;  2NL9 A;  1AF3 A;  4YJ4 A;  3IHD A;  3MQP A;  2VOI A;  3IIH A;  1YSN A;  4QVX A;  4HW4 A;  4BPI A;  5IF4 A;  2ABO A;  3KJ0 A;  4G35 A;  5C3F A;  4HW2 A;  3DVU A;  1WSX A;  5FDO A;  1R2I A;  2VM6 A;  2KUA A;  4BD8 A;  2O2M A;  2M5B A;  4ZEQ A;  3QBR A;  2ROC A;  3CVA X;  1YSW A;  4U2V A;  5C6H A;  2WH6 A;  1ZY3 A;  2LR1 A;  3MK8 A;  4YK9 A;  4BD7 A;  2MHS A;  2O2N A;  1BXL A;  1R2E A;  2JM6 B;  5FMI A;  1MK3 A;  1R2D A;  5IEZ A;  3IIG A;  2YV6 A;  1TY4 A;  2V6Q A;  2K7W A;  4HW3 A;  1LXL A;  1PQ0 A;  4MI8 A;  3KZ0 A;  2IMT A;  1MAZ A;  4ZIE A;  2BID A;  1R2H A;  2O21 A;  3PK1 A;  2O22 A;  3WIX A;  4BPJ A;  3D7V A;  4ZII A;  2NLA A;  4OQ6 A;  3KJ1 A;  2VOG A;  2VOH A;  1DDB A;  5FC4 A;  4ZIG A;  2BZW A;  3WIY A;  2ME8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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