2B5RC

1b lactamase / b lactamase inhibitor
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
165
structure length
165
Chain Sequence
AGVMTGAKFTQIQFGMTRQQVLDIAGAENCETGGSFGDSIHCRGHAAGDYYAYATFGFTSAAADAKVDSKSQEKLLAPSAPTLTLAKFNQVTVGMTRAQVLATVGQGSCTTWSEYYPAYPSTAGVTLSLSCFDVDGYSSTGFYRGSAHLWFTDGVLQGKRQWDLV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Binding Hot Spots in the TEM1-BLIP Interface in Light of its Modular Architecture.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Escherichia coli
molecule keywords Beta-lactamase TEM
total genus 46
structure length 165
sequence length 165
chains with identical sequence D
ec nomenclature
pdb deposition date 2005-09-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF07467 BLIP Beta-lactamase inhibitor (BLIP)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1450.10 Alpha Beta 2-Layer Sandwich Beta-lactamase Inhibitory Protein; Chain:B, domain 1 Beta-lactamase Inhibitory Protein; Chain:B, domain 1 2b5rC01
3.30.1450.10 Alpha Beta 2-Layer Sandwich Beta-lactamase Inhibitory Protein; Chain:B, domain 1 Beta-lactamase Inhibitory Protein; Chain:B, domain 1 2b5rC02
5D0QE 4DM5A 1S0WC 5D0OE 5AYWE 3D4EA 3E2KC 2PXGA 2G2WB 3C4OB 3N4IB 3E2LC 2YH9A 3C7VB 3GMUB 2B5RC 2G2UB 5EKQE 1XXMC 3C7UB 1JTGB 2KXXA 3C4PB 2KM7A
chains in the Genus database with same CATH superfamily
5D0QE 4DM5A 1S0WC 3NWDA 5D0OE 3NWFA 4HSIA 5AYWE 3D4EA 3E2KC 2PXGA 2G2WB 3C4OB 3NW8A 2GUMA 3N4IB 3E2LC 2YH9A 3C7VB 3GMUB 3FVCA 2B5RC 2G2UB 5EKQE 1XXMC 4L1RA 3C7UB 1JTGB 3NWAA 2KXXA 3C4PB 2KM7A
chains in the Genus database with same CATH topology
5D0QE 4DM5A 1S0WC 3NWDA 5D0OE 3NWFA 4HSIA 5AYWE 3D4EA 3E2KC 2PXGA 2G2WB 3C4OB 3NW8A 2GUMA 3N4IB 3E2LC 2YH9A 3C7VB 3GMUB 3FVCA 2B5RC 2G2UB 5EKQE 1XXMC 4L1RA 3C7UB 1JTGB 3NWAA 2KXXA 3C4PB 2KM7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5D0Q E;  4DM5 A;  1S0W C;  5D0O E;  5AYW E;  3D4E A;  3E2K C;  2PXG A;  2G2W B;  3C4O B;  3N4I B;  3E2L C;  2YH9 A;  3C7V B;  3GMU B;  2B5R C;  2G2U B;  5EKQ E;  1XXM C;  3C7U B;  1JTG B;  2KXX A;  3C4P B;  2KM7 A; 
#chains in the Genus database with same CATH topology
 5D0Q E;  4DM5 A;  1S0W C;  3NWD A;  5D0O E;  3NWF A;  4HSI A;  5AYW E;  3D4E A;  3E2K C;  2PXG A;  2G2W B;  3C4O B;  3NW8 A;  2GUM A;  3N4I B;  3E2L C;  2YH9 A;  3C7V B;  3GMU B;  3FVC A;  2B5R C;  2G2U B;  5EKQ E;  1XXM C;  4L1R A;  3C7U B;  1JTG B;  3NWA A;  2KXX A;  3C4P B;  2KM7 A; 
#chains in the Genus database with same CATH homology
 5D0Q E;  4DM5 A;  1S0W C;  3NWD A;  5D0O E;  3NWF A;  4HSI A;  5AYW E;  3D4E A;  3E2K C;  2PXG A;  2G2W B;  3C4O B;  3NW8 A;  2GUM A;  3N4I B;  3E2L C;  2YH9 A;  3C7V B;  3GMU B;  3FVC A;  2B5R C;  2G2U B;  5EKQ E;  1XXM C;  4L1R A;  3C7U B;  1JTG B;  3NWA A;  2KXX A;  3C4P B;  2KM7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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