2B5RC

1b lactamase / b lactamase inhibitor
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
165
structure length
165
Chain Sequence
AGVMTGAKFTQIQFGMTRQQVLDIAGAENCETGGSFGDSIHCRGHAAGDYYAYATFGFTSAAADAKVDSKSQEKLLAPSAPTLTLAKFNQVTVGMTRAQVLATVGQGSCTTWSEYYPAYPSTAGVTLSLSCFDVDGYSSTGFYRGSAHLWFTDGVLQGKRQWDLV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Binding Hot Spots in the TEM1-BLIP Interface in Light of its Modular Architecture.
pubmed doi rcsb
molecule keywords Beta-lactamase TEM
molecule tags Hydrolase/hydrolase inhibitor
source organism Escherichia coli
total genus 46
structure length 165
sequence length 165
chains with identical sequence D
ec nomenclature
pdb deposition date 2005-09-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF07467 BLIP Beta-lactamase inhibitor (BLIP)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1450.10 Alpha Beta 2-Layer Sandwich Beta-lactamase Inhibitory Protein; Chain:B, domain 1 Beta-lactamase Inhibitory Protein; Chain:B, domain 1 2b5rC01
3.30.1450.10 Alpha Beta 2-Layer Sandwich Beta-lactamase Inhibitory Protein; Chain:B, domain 1 Beta-lactamase Inhibitory Protein; Chain:B, domain 1 2b5rC02
3C7UB 2PXGA 5AYWE 5EKQE 3N4IB 1XXMC 1JTGB 1S0WC 2B5RC 2KXXA 3GMUB 3C7VB 3D4EA 5D0QE 3C4PB 5D0OE 3E2LC 3E2KC 2G2WB 4DM5A 2G2UB 2KM7A 3C4OB 2YH9A
chains in the Genus database with same CATH superfamily
3C7UB 2PXGA 2GUMA 5AYWE 3NW8A 5EKQE 3N4IB 1XXMC 4L1RA 1JTGB 1S0WC 2B5RC 2KXXA 3GMUB 3NWDA 3C7VB 3D4EA 5D0QE 3C4PB 3NWAA 5D0OE 3E2LC 3FVCA 4HSIA 3E2KC 2G2WB 3NWFA 4DM5A 2G2UB 2KM7A 3C4OB 2YH9A
chains in the Genus database with same CATH topology
3C7UB 2PXGA 2GUMA 5AYWE 3NW8A 5EKQE 3N4IB 1XXMC 4L1RA 1JTGB 1S0WC 2B5RC 2KXXA 3GMUB 3NWDA 3C7VB 3D4EA 5D0QE 3C4PB 3NWAA 5D0OE 3E2LC 3FVCA 4HSIA 3E2KC 2G2WB 3NWFA 4DM5A 2G2UB 2KM7A 3C4OB 2YH9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3C7U B;  2PXG A;  5AYW E;  5EKQ E;  3N4I B;  1XXM C;  1JTG B;  1S0W C;  2B5R C;  2KXX A;  3GMU B;  3C7V B;  3D4E A;  5D0Q E;  3C4P B;  5D0O E;  3E2L C;  3E2K C;  2G2W B;  4DM5 A;  2G2U B;  2KM7 A;  3C4O B;  2YH9 A; 
#chains in the Genus database with same CATH topology
 3C7U B;  2PXG A;  2GUM A;  5AYW E;  3NW8 A;  5EKQ E;  3N4I B;  1XXM C;  4L1R A;  1JTG B;  1S0W C;  2B5R C;  2KXX A;  3GMU B;  3NWD A;  3C7V B;  3D4E A;  5D0Q E;  3C4P B;  3NWA A;  5D0O E;  3E2L C;  3FVC A;  4HSI A;  3E2K C;  2G2W B;  3NWF A;  4DM5 A;  2G2U B;  2KM7 A;  3C4O B;  2YH9 A; 
#chains in the Genus database with same CATH homology
 3C7U B;  2PXG A;  2GUM A;  5AYW E;  3NW8 A;  5EKQ E;  3N4I B;  1XXM C;  4L1R A;  1JTG B;  1S0W C;  2B5R C;  2KXX A;  3GMU B;  3NWD A;  3C7V B;  3D4E A;  5D0Q E;  3C4P B;  3NWA A;  5D0O E;  3E2L C;  3FVC A;  4HSI A;  3E2K C;  2G2W B;  3NWF A;  4DM5 A;  2G2U B;  2KM7 A;  3C4O B;  2YH9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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