2BZWA

The crystal structure of bcl-xl in complex with full-length bad
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
195
structure length
144
Chain Sequence
SQSNRELVVDFLSYKLSQKGYSWSQFSDIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLYG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and Biochemical Bases for the Inhibition of Autophagy and Apoptosis by Viral Bcl-2 of Murine Gamma-Herpesvirus 68.
pubmed doi rcsb
molecule tags Transcription
source organism Mus musculus
molecule keywords APOPTOSIS REGULATOR BCL-X
total genus 59
structure length 144
sequence length 195
ec nomenclature
pdb deposition date 2005-08-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00452 Bcl-2 Apoptosis regulator proteins, Bcl-2 family
A PF02180 BH4 Bcl-2 homology region 4
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.437.10 Mainly Alpha Orthogonal Bundle Apoptosis Regulator Bcl-x Blc2-like 2bzwA00
3IIHA 2KBWA 2VOFA 2W3LA 5FC4A 4ZEQA 4K5BC 2IMTA 4WMRA 1YSWA 1R2HA 2ROCA 2MHSA 5IEZA 2XA0A 2B48A 2VOGA 1F16A 4OYDA 4HW4A 1PQ1A 2K7WA 5C3FA 1AF3A 4ZBFA 4ZIFA 3ILCA 3D7VA 1OHUA 1ZY3A 1R2EA 2VOIA 1O0LA 4OQ6A 4S0PA 3IIGA 5FDOA 2V6QA 2KUAA 3QBRA 3KJ0A 2ME8A 4OQ5A 5FDRA 4QVXA 2VOHA 4ZIGA 5KU9A 1R2IA 3IO9A 1MK3A 4G35A 3I1HA 1YSNA 1Q59A 5KTGA 4BD8A 5C6HA 3WIYA 2O2FA 5IF4A 2O21A 3KJ1A 2NLAA 3PK1A 4BPIA 1DDBA 2XPXA 1G5MA 1G5JA 4ZIEA 2VM6A 1YSGA 2O2MA 4BDUA 1BXLA 4ZBIA 1R2GA 2A5YA 3KZ0A 2YV6A 1GJHA 4U2VA 3IHEA 4S0OA 1YSIA 2O2NA 2JCNA 1R2DA 4QNQA 3IHCA 3CVAX 1TY4A 1PQ0A 4ZIIA 2BZWA 2NL9A 2MEJA 2BIDA 4MI8A 2IMSA 4YK9A 2RODA 4ZIHA 3MK8A 4BD2A 2JM6B 1LXLA 2PQKA 3IHDA 3KJ2A 4BD6A 4B4SA 4HW2A 4YJ4A 3WIXA 5JSBA 1K3KA 2LR1A 4BD7A 3BL2A 4U2UA 2ABOA 4HW3A 2O22A 4BPJA 1WSXA 1MAZA 5FMIA 2M5BA 2WH6A 3MQPA 3DVUA
chains in the Genus database with same CATH superfamily
3IIHA 2KBWA 2VOFA 2VVXA 2W3LA 4M0SA 5FC4A 4ZEQA 4K5BC 4UF2A 2IMTA 4WMRA 1YSWA 1R2HA 2ROCA 2MHSA 5IEZA 2XA0A 2B48A 2VOGA 1F16A 4OYDA 4HW4A 1PQ1A 2K7WA 5C3FA 1AF3A 4ZBFA 4BBBA 4ZIFA 3ILCA 3D7VA 1OHUA 1ZY3A 4BBDA 1R2EA 2VOIA 1O0LA 4OQ6A 3JRVA 4S0PA 3IIGA 2O42A 4D2LA 5FDOA 2V6QA 2KUAA 3QBRA 3KJ0A 2ME8A 4OQ5A 5FDRA 4QVXA 2VOHA 4ZIGA 5KU9A 1R2IA 3IO9A 1MK3A 4G35A 3I1HA 1YSNA 1Q59A 5KTGA 4BD8A 5C6HA 3WIYA 2O2FA 5IF4A 2O21A 3KJ1A 2NLAA 3PK1A 4BPIA 1DDBA 2XPXA 1G5MA 1G5JA 4ZIEA 2VM6A 1YSGA 2O2MA 2VTYA 4BDUA 1BXLA 4ZBIA 1R2GA 2A5YA 3KZ0A 2YV6A 1GJHA 4U2VA 3IHEA 4S0OA 4UF1A 1YSIA 2O2NA 2JCNA 4LQKA 1R2DA 4QNQA 3IHCA 3CVAX 1TY4A 1PQ0A 4ZIIA 2BZWA 2NL9A 2MEJA 2BIDA 2VVYA 4MI8A 2IMSA 4YK9A 2RODA 4ZIHA 3MK8A 4BD2A 2JM6B 1LXLA 2UXEA 2PQKA 4UF3A 3IHDA 3KJ2A 4BD6A 4D2MA 2VVWA 4B4SA 4HW2A 4YJ4A 3WIXA 5JSBA 1K3KA 2LR1A 4BD7A 3BL2A 2K36A 4U2UA 2JBYA 2ABOA 2JBXA 4HW3A 2O22A 4BPJA 1WSXA 1MAZA 5FMIA 4BBCA 2M5BA 2WH6A 3MQPA 2I39A 3DVUA
chains in the Genus database with same CATH topology
3IIHA 2KBWA 2VOFA 2W3LA 5FC4A 4ZEQA 4K5BC 2IMTA 4WMRA 1YSWA 1R2HA 2ROCA 2MHSA 5IEZA 2XA0A 2B48A 2VOGA 1F16A 4OYDA 4HW4A 1PQ1A 2K7WA 5C3FA 1AF3A 4ZBFA 4ZIFA 3ILCA 3D7VA 1OHUA 1ZY3A 1R2EA 2VOIA 1O0LA 4OQ6A 4S0PA 3IIGA 5FDOA 2V6QA 2KUAA 3QBRA 3KJ0A 2ME8A 4OQ5A 5FDRA 4QVXA 2VOHA 4ZIGA 5KU9A 1R2IA 3IO9A 1MK3A 4G35A 3I1HA 1YSNA 1Q59A 5KTGA 4BD8A 5C6HA 3WIYA 2O2FA 5IF4A 2O21A 3KJ1A 2NLAA 3PK1A 4BPIA 1DDBA 2XPXA 1G5MA 1G5JA 4ZIEA 2VM6A 1YSGA 2O2MA 4BDUA 1BXLA 4ZBIA 1R2GA 2A5YA 3KZ0A 2YV6A 1GJHA 4U2VA 3IHEA 4S0OA 1YSIA 2O2NA 2JCNA 1R2DA 4QNQA 3IHCA 3CVAX 1TY4A 1PQ0A 4ZIIA 2BZWA 2NL9A 2MEJA 2BIDA 4MI8A 2IMSA 4YK9A 2RODA 4ZIHA 3MK8A 4BD2A 2JM6B 1LXLA 2PQKA 3IHDA 3KJ2A 4BD6A 4B4SA 4HW2A 4YJ4A 3WIXA 5JSBA 1K3KA 2LR1A 4BD7A 3BL2A 4U2UA 2ABOA 4HW3A 2O22A 4BPJA 1WSXA 1MAZA 5FMIA 2M5BA 2WH6A 3MQPA 3DVUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3IIH A;  2KBW A;  2VOF A;  2W3L A;  5FC4 A;  4ZEQ A;  4K5B C;  2IMT A;  4WMR A;  1YSW A;  1R2H A;  2ROC A;  2MHS A;  5IEZ A;  2XA0 A;  2B48 A;  2VOG A;  1F16 A;  4OYD A;  4HW4 A;  1PQ1 A;  2K7W A;  5C3F A;  1AF3 A;  4ZBF A;  4ZIF A;  3ILC A;  3D7V A;  1OHU A;  1ZY3 A;  1R2E A;  2VOI A;  1O0L A;  4OQ6 A;  4S0P A;  3IIG A;  5FDO A;  2V6Q A;  2KUA A;  3QBR A;  3KJ0 A;  2ME8 A;  4OQ5 A;  5FDR A;  4QVX A;  2VOH A;  4ZIG A;  5KU9 A;  1R2I A;  3IO9 A;  1MK3 A;  4G35 A;  3I1H A;  1YSN A;  1Q59 A;  5KTG A;  4BD8 A;  5C6H A;  3WIY A;  2O2F A;  5IF4 A;  2O21 A;  3KJ1 A;  2NLA A;  3PK1 A;  4BPI A;  1DDB A;  2XPX A;  1G5M A;  1G5J A;  4ZIE A;  2VM6 A;  1YSG A;  2O2M A;  4BDU A;  1BXL A;  4ZBI A;  1R2G A;  2A5Y A;  3KZ0 A;  2YV6 A;  1GJH A;  4U2V A;  3IHE A;  4S0O A;  1YSI A;  2O2N A;  2JCN A;  1R2D A;  4QNQ A;  3IHC A;  3CVA X;  1TY4 A;  1PQ0 A;  4ZII A;  2BZW A;  2NL9 A;  2MEJ A;  2BID A;  4MI8 A;  2IMS A;  4YK9 A;  2ROD A;  4ZIH A;  3MK8 A;  4BD2 A;  2JM6 B;  1LXL A;  2PQK A;  3IHD A;  3KJ2 A;  4BD6 A;  4B4S A;  4HW2 A;  4YJ4 A;  3WIX A;  5JSB A;  1K3K A;  2LR1 A;  4BD7 A;  3BL2 A;  4U2U A;  2ABO A;  4HW3 A;  2O22 A;  4BPJ A;  1WSX A;  1MAZ A;  5FMI A;  2M5B A;  2WH6 A;  3MQP A;  3DVU A; 
#chains in the Genus database with same CATH topology
 3IIH A;  2KBW A;  2VOF A;  2VVX A;  2W3L A;  4M0S A;  5FC4 A;  4ZEQ A;  4K5B C;  4UF2 A;  2IMT A;  4WMR A;  1YSW A;  1R2H A;  2ROC A;  2MHS A;  5IEZ A;  2XA0 A;  2B48 A;  2VOG A;  1F16 A;  4OYD A;  4HW4 A;  1PQ1 A;  2K7W A;  5C3F A;  1AF3 A;  4ZBF A;  4BBB A;  4ZIF A;  3ILC A;  3D7V A;  1OHU A;  1ZY3 A;  4BBD A;  1R2E A;  2VOI A;  1O0L A;  4OQ6 A;  3JRV A;  4S0P A;  3IIG A;  2O42 A;  4D2L A;  5FDO A;  2V6Q A;  2KUA A;  3QBR A;  3KJ0 A;  2ME8 A;  4OQ5 A;  5FDR A;  4QVX A;  2VOH A;  4ZIG A;  5KU9 A;  1R2I A;  3IO9 A;  1MK3 A;  4G35 A;  3I1H A;  1YSN A;  1Q59 A;  5KTG A;  4BD8 A;  5C6H A;  3WIY A;  2O2F A;  5IF4 A;  2O21 A;  3KJ1 A;  2NLA A;  3PK1 A;  4BPI A;  1DDB A;  2XPX A;  1G5M A;  1G5J A;  4ZIE A;  2VM6 A;  1YSG A;  2O2M A;  2VTY A;  4BDU A;  1BXL A;  4ZBI A;  1R2G A;  2A5Y A;  3KZ0 A;  2YV6 A;  1GJH A;  4U2V A;  3IHE A;  4S0O A;  4UF1 A;  1YSI A;  2O2N A;  2JCN A;  4LQK A;  1R2D A;  4QNQ A;  3IHC A;  3CVA X;  1TY4 A;  1PQ0 A;  4ZII A;  2BZW A;  2NL9 A;  2MEJ A;  2BID A;  2VVY A;  4MI8 A;  2IMS A;  4YK9 A;  2ROD A;  4ZIH A;  3MK8 A;  4BD2 A;  2JM6 B;  1LXL A;  2UXE A;  2PQK A;  4UF3 A;  3IHD A;  3KJ2 A;  4BD6 A;  4D2M A;  2VVW A;  4B4S A;  4HW2 A;  4YJ4 A;  3WIX A;  5JSB A;  1K3K A;  2LR1 A;  4BD7 A;  3BL2 A;  2K36 A;  4U2U A;  2JBY A;  2ABO A;  2JBX A;  4HW3 A;  2O22 A;  4BPJ A;  1WSX A;  1MAZ A;  5FMI A;  4BBC A;  2M5B A;  2WH6 A;  3MQP A;  2I39 A;  3DVU A; 
#chains in the Genus database with same CATH homology
 3IIH A;  2KBW A;  2VOF A;  2W3L A;  5FC4 A;  4ZEQ A;  4K5B C;  2IMT A;  4WMR A;  1YSW A;  1R2H A;  2ROC A;  2MHS A;  5IEZ A;  2XA0 A;  2B48 A;  2VOG A;  1F16 A;  4OYD A;  4HW4 A;  1PQ1 A;  2K7W A;  5C3F A;  1AF3 A;  4ZBF A;  4ZIF A;  3ILC A;  3D7V A;  1OHU A;  1ZY3 A;  1R2E A;  2VOI A;  1O0L A;  4OQ6 A;  4S0P A;  3IIG A;  5FDO A;  2V6Q A;  2KUA A;  3QBR A;  3KJ0 A;  2ME8 A;  4OQ5 A;  5FDR A;  4QVX A;  2VOH A;  4ZIG A;  5KU9 A;  1R2I A;  3IO9 A;  1MK3 A;  4G35 A;  3I1H A;  1YSN A;  1Q59 A;  5KTG A;  4BD8 A;  5C6H A;  3WIY A;  2O2F A;  5IF4 A;  2O21 A;  3KJ1 A;  2NLA A;  3PK1 A;  4BPI A;  1DDB A;  2XPX A;  1G5M A;  1G5J A;  4ZIE A;  2VM6 A;  1YSG A;  2O2M A;  4BDU A;  1BXL A;  4ZBI A;  1R2G A;  2A5Y A;  3KZ0 A;  2YV6 A;  1GJH A;  4U2V A;  3IHE A;  4S0O A;  1YSI A;  2O2N A;  2JCN A;  1R2D A;  4QNQ A;  3IHC A;  3CVA X;  1TY4 A;  1PQ0 A;  4ZII A;  2BZW A;  2NL9 A;  2MEJ A;  2BID A;  4MI8 A;  2IMS A;  4YK9 A;  2ROD A;  4ZIH A;  3MK8 A;  4BD2 A;  2JM6 B;  1LXL A;  2PQK A;  3IHD A;  3KJ2 A;  4BD6 A;  4B4S A;  4HW2 A;  4YJ4 A;  3WIX A;  5JSB A;  1K3K A;  2LR1 A;  4BD7 A;  3BL2 A;  4U2U A;  2ABO A;  4HW3 A;  2O22 A;  4BPJ A;  1WSX A;  1MAZ A;  5FMI A;  2M5B A;  2WH6 A;  3MQP A;  3DVU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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