2E52A

Crystal structural analysis of hindiii restriction endonuclease in complex with cognate dna at 2.0 angstrom resolution
Total Genus 116
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
116
sequence length
299
structure length
299
Chain Sequence
KKSALEKLLSLIENLTNQEFKQATNSLISFIYKLNRNEVIELVRSIGILPEAIKPSSTQEKLFSKAGDIVLAKAFQLLNLNSKPLEQRGNAGDVIALSKEFNYGLVADAKSFRLSRTAKNQKDFKVKALSEWREDKDYAVLTAPFFQYPTTKSQIFKQSLDENVLLFSWEHLAILLQLDLEETNIFSFEQLWNFPKKQSKKTSVSDAENNFMRDFNKYFMDLFKIDKDTLNQLLQKEINFIEERSLIEKEYWKKQINIIKNFTREEAIEALLKDINMSSKIETIDSFIKGIKSNDRLYL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of restriction endonuclease HindIII in complex with its cognate DNA and divalent cations
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Haemophilus influenzae
molecule keywords Type II restriction enzyme HindIII
total genus 116
structure length 299
sequence length 299
chains with identical sequence B, C, D
ec nomenclature ec 3.1.21.4: Type II site-specific deoxyribonuclease.
pdb deposition date 2006-12-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09518 RE_HindIII HindIII restriction endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.91.70 Alpha Beta 3-Layer(aba) Sandwich Restriction Endonuclease Restriction Endonuclease 2e52A01
3WVIA 3A4KA 3WVPA 2E52A 3WVKA 3WVGA 3WVHA
chains in the Genus database with same CATH superfamily
3MQYA 3V1ZA 2FQZA 5FDGA 1ES8A 3V21A 4AWHA 1CFRA 4ZQQA 5CGVA 3V20A 1FZRA 4AWGA 2BAMA 1DFMA 2P0JA 5FDDA 3HW6A 3WVIA 5JHVA 1BAMA 3BM3A 3WVGA 5DESA 2PFJA 3HW5A 1BHMA 2P14A 4E5EA 4AWFA 1KNVA 4AWMA 4YYLA 4AVLA 4F0QA 5JHTA 5CL0A 1VRRA 4E5GA 4CHCA 1ESGA 2XI7A 1M0IA 3N7BA 2E52A 4AVGA 4NFZA 2EWFA 2FOKA 5D42A 4E5JA 3WVKA 3CAEA 3EBJA 3BAMA 4OC8A 5DBSA 3HW4A 5I13A 5DEBA 3A4KA 1FOKA 3DVOA 5CCYA 3HW3A 5D9JA 4AVQA 4ZI0A 3ODHA 5EGAA 3MQ6A 2XI5A 4ZHZA 4E5IA 4R28A 3WVHA 1M0DA 4CGXA 3N78A 5D8UA 4E5LA 5D2OA 5D4GA 1DC1A 4F0PA 4E5HA 2GB7A 5CZNA 1SDOA 3DW9A 4CGSA 3DPGA 3WVPA 1D2IA 4AWKA 4E5FA
chains in the Genus database with same CATH topology
3MQYA 3V1ZA 2FQZA 5FDGA 1ES8A 3V21A 4AWHA 1CFRA 4ZQQA 5CGVA 3V20A 1FZRA 4AWGA 2BAMA 1DFMA 2P0JA 5FDDA 3HW6A 3WVIA 5JHVA 1BAMA 3BM3A 3WVGA 5DESA 2PFJA 3HW5A 1BHMA 2P14A 4E5EA 4AWFA 1KNVA 4AWMA 4YYLA 4AVLA 4F0QA 5JHTA 5CL0A 1VRRA 4E5GA 4CHCA 1ESGA 2XI7A 1M0IA 3N7BA 2E52A 4AVGA 4NFZA 2EWFA 2FOKA 5D42A 4E5JA 3WVKA 3CAEA 3EBJA 3BAMA 4OC8A 5DBSA 3HW4A 5I13A 5DEBA 3A4KA 1FOKA 3DVOA 5CCYA 3HW3A 5D9JA 4AVQA 4ZI0A 3ODHA 5EGAA 3MQ6A 2XI5A 4ZHZA 4E5IA 4R28A 3WVHA 1M0DA 4CGXA 3N78A 5D8UA 4E5LA 5D2OA 5D4GA 1DC1A 4F0PA 4E5HA 2GB7A 5CZNA 1SDOA 3DW9A 4CGSA 3DPGA 3WVPA 1D2IA 4AWKA 4E5FA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3WVI A;  3A4K A;  3WVP A;  2E52 A;  3WVK A;  3WVG A;  3WVH A; 
#chains in the Genus database with same CATH topology
 3MQY A;  3V1Z A;  2FQZ A;  5FDG A;  1ES8 A;  3V21 A;  4AWH A;  1CFR A;  4ZQQ A;  5CGV A;  3V20 A;  1FZR A;  4AWG A;  2BAM A;  1DFM A;  2P0J A;  5FDD A;  3HW6 A;  3WVI A;  5JHV A;  1BAM A;  3BM3 A;  3WVG A;  5DES A;  2PFJ A;  3HW5 A;  1BHM A;  2P14 A;  4E5E A;  4AWF A;  1KNV A;  4AWM A;  4YYL A;  4AVL A;  4F0Q A;  5JHT A;  5CL0 A;  1VRR A;  4E5G A;  4CHC A;  1ESG A;  2XI7 A;  1M0I A;  3N7B A;  2E52 A;  4AVG A;  4NFZ A;  2EWF A;  2FOK A;  5D42 A;  4E5J A;  3WVK A;  3CAE A;  3EBJ A;  3BAM A;  4OC8 A;  5DBS A;  3HW4 A;  5I13 A;  5DEB A;  3A4K A;  1FOK A;  3DVO A;  5CCY A;  3HW3 A;  5D9J A;  4AVQ A;  4ZI0 A;  3ODH A;  5EGA A;  3MQ6 A;  2XI5 A;  4ZHZ A;  4E5I A;  4R28 A;  3WVH A;  1M0D A;  4CGX A;  3N78 A;  5D8U A;  4E5L A;  5D2O A;  5D4G A;  1DC1 A;  4F0P A;  4E5H A;  2GB7 A;  5CZN A;  1SDO A;  3DW9 A;  4CGS A;  3DPG A;  3WVP A;  1D2I A;  4AWK A;  4E5F A; 
#chains in the Genus database with same CATH homology
 3MQY A;  3V1Z A;  2FQZ A;  5FDG A;  1ES8 A;  3V21 A;  4AWH A;  1CFR A;  4ZQQ A;  5CGV A;  3V20 A;  1FZR A;  4AWG A;  2BAM A;  1DFM A;  2P0J A;  5FDD A;  3HW6 A;  3WVI A;  5JHV A;  1BAM A;  3BM3 A;  3WVG A;  5DES A;  2PFJ A;  3HW5 A;  1BHM A;  2P14 A;  4E5E A;  4AWF A;  1KNV A;  4AWM A;  4YYL A;  4AVL A;  4F0Q A;  5JHT A;  5CL0 A;  1VRR A;  4E5G A;  4CHC A;  1ESG A;  2XI7 A;  1M0I A;  3N7B A;  2E52 A;  4AVG A;  4NFZ A;  2EWF A;  2FOK A;  5D42 A;  4E5J A;  3WVK A;  3CAE A;  3EBJ A;  3BAM A;  4OC8 A;  5DBS A;  3HW4 A;  5I13 A;  5DEB A;  3A4K A;  1FOK A;  3DVO A;  5CCY A;  3HW3 A;  5D9J A;  4AVQ A;  4ZI0 A;  3ODH A;  5EGA A;  3MQ6 A;  2XI5 A;  4ZHZ A;  4E5I A;  4R28 A;  3WVH A;  1M0D A;  4CGX A;  3N78 A;  5D8U A;  4E5L A;  5D2O A;  5D4G A;  1DC1 A;  4F0P A;  4E5H A;  2GB7 A;  5CZN A;  1SDO A;  3DW9 A;  4CGS A;  3DPG A;  3WVP A;  1D2I A;  4AWK A;  4E5F A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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