2EWFA

Crystal structure of the site-specific dna nickase n.bspd6i
Total Genus 238
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
238
sequence length
604
structure length
587
Chain Sequence
MAKKVNWYVSCSPRSPEKIQPELKVLANFEGSYWKGVKGYKAQEAFAKELAALPQFLGAFSTRDRVAPMKTYGFVFVDEEGYLRITEAGKMLANNRRPKDVFLKQLVKWQYPSFQHKGKEYPEEEWSINPLVFVLSLLKKVGGLSKLDIAMFCLTATNNNQVDEIAEEIMQFRNEREKIKGQNKKLEFTENYFFKRFEKIYGNVSHKSKIETKMRNARDVADATTRYFRYTGLFVARGNQLVLNPEKSDLIDEIISSSKVVKNYTRVEEFHEYYGNPSLPQFSFETKEQLLDLAHRIRDENTRLAEQLVEHFPNVKVEIQVLEDIYNSLNKKVDVETLKDVIYHAKELQLELKKKKLQADFNDPRQLEEVIDLLEVYHEKKNVIEEKIKARFIANKNTVFEWLTWNGFIILGNALEYKNNFVIDEELQPVTHAAGNQPDMEIIYEDFIVLGEVTTSKGATQFKMESEPVTRHYLNKKKELEKQGVEKELYCLFIAPEINKNTFEEFMKYNIVQNTRIIPLSLKQFNMLLMVQKKLIEKGRRLSSYDIKNLMVSLYRTTIECERKYTQIKAGLEETLNNWVVDKEVRF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hydrolase
molecule keywords Nicking endonuclease N.BspD6I
publication title Structural analysis of the heterodimeric type IIS restriction endonuclease R.BspD6I acting as a complex between a monomeric site-specific nickase and a catalytic subunit.
pubmed doi rcsb
source organism Bacillus sp.
total genus 238
structure length 587
sequence length 604
ec nomenclature
pdb deposition date 2005-11-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09491 RE_AlwI AlwI restriction endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.310 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Substrate Binding Domain Of Dnak; Chain:A; Domain 2 2ewfA02
3.40.91.50 Alpha Beta 3-Layer(aba) Sandwich Restriction Endonuclease Restriction Endonuclease 2ewfA03
2EWFA 2P14A
chains in the Genus database with same CATH superfamily
4AWHA 1GNLA 1X04A 1DKZA 4EZTA 4E5HA 2V0OA 4AZGA 2RAJA 1M0IA 3FD9A 3DX3A 3EJTA 2EX3B 4NQIA 3V1ZA 2ZXQA 4WPCA 1R5EA 4JWCA 3CV5A 3DX4A 3O3NB 5D8UA 1TQUA 4CHCA 3HAHA 4F01A 1ESGA 4JL9A 2ELBA 3N78A 3SOGA 2GA9D 3HW3A 1R33A 3M3WA 3O3OB 3VEAA 3T48A 3HAJA 4EZQA 1U00A 4E81A 2Z0NA 3ACOA 2F7QA 4CGSA 2YI9A 4FZOA 3BLBA 3ER9B 4EZWA 1ZWWA 1UPXA 1QX1A 2YL8A 4IM3A 4AZBA 1TQTA 3KDRA 1DC1A 3DX0A 4R28A 2PMRA 1E1DA 4E5GA 2X5CA 3D2EA 2EFLA 1BAMA 2F1AA 1HWWA 4EZNA 3LMFA 4KIKA 2F7OA 1TQWA 4E5IA 5I13A 5TKYA 4F0QA 4WPEA 3F7WA 3WVGA 3UITA 1OAOA 3I01A 4HYBA 4OC8A 4AWKA 3DX2A 4NPHA 3CZSA 3BVVA 3L3PA 4R5IA 3BUQA 3EJQA 3G9GA 1GN9A 2Z0VA 3ERCC 2XI5A 2QKWA 3BUIA 2D4CA 4F00A 3EBJA 2YL5A 3WVHA 3DX1A 5JHVA 3BVTA 4IWPA 3CKDA 4NFZA 3BAMA 4NSWA 2WYHA 4BNEA 3T46A 1SU6A 2P0JA 4JWIA 4R5KA 5KBPA 3DVOA 3RPMA 2EWFA 4IW0A 2QXLA 3BVXA 2YLLA 4AZ6A 3D2FA 4E5JA 4AVMA 4EZVA 3BUPA 3DW9A 1W9MA 1URUA 2Z8YA 1D2IA 2WYIA 4DYLA 1X03A 4H6IA 3C7NA 1I4TA 3V20A 4R5LA 3I04A 2QFFA 1FZRA 4F0PA 2JNSA 3OHXM 3L3OM 2OZNB 5E84A 2PY6A 5C5BB 2GF4A 3QNJA 2BAMA 5FDGA 4ATMA 1HTYA 2X3XA 4CGXA 3B52X 3DDFA 3BVUA 4ZI0A 4PO2A 3HW5A 1E2UA 1JQKA 3D50A 2E52A 4H8SA 3WVPA 5FIGA 3SYVA 3WVIA 4AVLA 4EZYA 1YWMA 4AWGA 3HW4A 4AZCB 4AZIA 2LXYA 3CZNA 3D4ZA 4UDYX 3DDGA 4ZHZA 2ND0A 3LLLA 1HXKA 3KAVA 1DFMA 2P14A 1SU8A 3KAWA 2XI7A 2FYVA 3DYTA 1OA1A 3T49A 2FICA 2YL9A 5EGAA 3QE6A 4EZXA 2F7RA 4AVGA 2ALWA 3ABHA 2Q12A 4M0MA 4EZPA 1M0DA 4AZCA 2FOKA 1KNVA 3A4KA 2YI8A 3Q84A 4IM0A 2KHOA 2C08A 2Z0OA 2PFJA 4G6QA 2RAIA 2X3WA 4IM2A 1O7DB 4FM3A 4E3CA 1DKYA 2N3KA 1OA0A 4HR1B 2X3VA 4I1QA 3VKHA 3GI7A 4AWMA 1I49A 3EJSA 4JWEA 2MI7A 5FLEX 1WDZA 1MJGA 1SDOA 4E5LA 4HY9A 3T4AG 3T47A 1E9VA 3EJUA 3BVWA 1TQSA 3CVRA 2JNKA 4AVQA 1QWNA 4AWFA 4ZQQA 5CL0A 5CCYA 4D8JA 2GB7A 4R5JA 1I4DA 1FOKA 1BHMA 1SU7A 3ER8C 4IWOA 2OO2A 3ODHA 2RT6A 3B51X 4AKVA 3DPOA 4JNEA 3BUDA 4R5GA 4YYLA 3A98A 3D4YA 2O0I1 2OW7A 4FZSA 3EJPA 1GNTA 4AZHA 4JWDA 5DESA 4AZ5A 3DPQA 3OK8A 3I39X 3CAEA 3RV1A 3ZEDA 4DCNC 2EFKA 2Q13A 4UDXX 3VEBA 2F1BA 3RV0A 2FQZA 4EZUA 4AZ7A 3O3MB 4JNFA 2YIVX 4IWQA 3LVTA 3HW6A 4KIKB 4E5FA 5C5BA 2LM0A 1Y2OA 5JHTA 4EZZA 4EZOA 2F7PA 3BM3A 1TQVA 3WVKA 3V21A 3DPPA 3I2WA 3OWGA 3PLTA 3D51A 3DPGA 2D1LA 1PS3A 4JLCA 2NCZA 2ND1A 5D9JA 4JN4A 3QNIA 1ES8A 5CGVA 4FZPA 3CAZA 1VRRA 4E5EA 2YKTA 1LQ7A 3BUBA 1QWUA 3QWEA 3MQ6A 4B9QA 2YIBA 3D52A 5DEBA 1DKXA 1SUFA 1R34A 5CZNA 3N7BA 5D4GA 5D2OA 3B53X 2RAKA 2F18A 5FDDA 4H6HA 3HAIA 4EZSA 2OW6A 2OBMA 1O7DC 2YIAA 2OBLA 3Q0KA 5D42A 1ZYLA 3QA8A 4EZRA 1CFRA 3MQYA 2YLAA 2YL6A 2WINM 3EJRA 1I4LA 2GAFD 4HR1A 5DBSA
chains in the Genus database with same CATH topology
5DESA 4NPHA 4AWHA 3DPQA 4UDYX 1GNLA 3I39X 4R5IA 1DKZA 3CAEA 4EZTA 4E5HA 4ZHZA 1GN9A 3RV1A 2ND0A 3ZEDA 3ERCC 3KAVA 2XI5A 1DFMA 1M0IA 3FD9A 4F00A 1SU8A 2P14A 2EX3B 3EBJA 3KAWA 3V1ZA 2XI7A 4UDXX 3WVHA 3VEBA 1OA1A 3T49A 5JHVA 4JWCA 4IWPA 3RV0A 5EGAA 4NFZA 4EZXA 3BAMA 3O3NB 5D8UA 2FQZA 4AVGA 4EZUA 4CHCA 3T46A 4M0MA 1SU6A 3O3MB 4JNFA 2YIVX 4IWQA 4EZPA 4F01A 4JWIA 4JL9A 1M0DA 3HW6A 1ESGA 2P0JA 4KIKB 4E5FA 2FOKA 1KNVA 3A4KA 2LM0A 4R5KA 2YI8A 3N78A 4IM0A 2KHOA 4EZZA 4EZOA 5JHTA 3BM3A 3DVOA 2PFJA 3WVKA 3V21A 3DPPA 4G6QA 3OWGA 2GA9D 2EWFA 3HW3A 4IM2A 4IW0A 2QXLA 4FM3A 3O3OB 3DPGA 4E3CA 3D2FA 3VEAA 4E5JA 1DKYA 3T48A 2N3KA 4JLCA 4EZVA 3DW9A 1OA0A 2NCZA 1W9MA 4HR1B 4EZQA 1U00A 4E81A 2ND1A 2Z8YA 1D2IA 5D9JA 4JN4A 3VKHA 4CGSA 2YI9A 1ES8A 5CGVA 3GI7A 4AWMA 3ER9B 4EZWA 1VRRA 4H6IA 4JWEA 4E5EA 5FLEX 3C7NA 3MQ6A 1MJGA 1SDOA 4B9QA 1UPXA 2YIBA 4E5LA 4HY9A 3V20A 4R5LA 3T4AG 5DEBA 1DKXA 3I04A 2QFFA 3T47A 1SUFA 1FZRA 1E9VA 5CZNA 4F0PA 3N7BA 2JNSA 4IM3A 5D4GA 5D2OA 3B53X 3KDRA 1DC1A 3OHXM 3L3OM 4AVQA 5FDDA 4AWFA 5E84A 4R28A 4ZQQA 2PY6A 4H6HA 5CL0A 5CCYA 1E1DA 4D8JA 2X5CA 3D2EA 4E5GA 1BAMA 2GB7A 4R5JA 3QNJA 4EZNA 4EZSA 1FOKA 3LMFA 4KIKA 1BHMA 2BAMA 1SU7A 3ER8C 4E5IA 4IWOA 5FDGA 5I13A 5TKYA 3ODHA 2OBMA 2YIAA 4F0QA 2OBLA 2RT6A 3B51X 4CGXA 3F7WA 3B52X 3DPOA 4JNEA 5D42A 4R5GA 4YYLA 4ZI0A 1ZYLA 3A98A 3QA8A 4EZRA 4PO2A 3HW5A 1CFRA 1E2UA 1JQKA 3UITA 3WVGA 3MQYA 2E52A 2WINM 3WVPA 5FIGA 1GNTA 3WVIA 1OAOA 4AVLA 4EZYA 4AWGA 3I01A 4HYBA 2GAFD 4OC8A 4AWKA 3HW4A 4HR1A 4JWDA 5DBSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EWF A;  2P14 A; 
#chains in the Genus database with same CATH topology
 4AWH A;  1GNL A;  1X04 A;  1DKZ A;  4EZT A;  4E5H A;  2V0O A;  4AZG A;  2RAJ A;  1M0I A;  3FD9 A;  3DX3 A;  3EJT A;  2EX3 B;  4NQI A;  3V1Z A;  2ZXQ A;  4WPC A;  1R5E A;  4JWC A;  3CV5 A;  3DX4 A;  3O3N B;  5D8U A;  1TQU A;  4CHC A;  3HAH A;  4F01 A;  1ESG A;  4JL9 A;  2ELB A;  3N78 A;  3SOG A;  2GA9 D;  3HW3 A;  1R33 A;  3M3W A;  3O3O B;  3VEA A;  3T48 A;  3HAJ A;  4EZQ A;  1U00 A;  4E81 A;  2Z0N A;  3ACO A;  2F7Q A;  4CGS A;  2YI9 A;  4FZO A;  3BLB A;  3ER9 B;  4EZW A;  1ZWW A;  1UPX A;  1QX1 A;  2YL8 A;  4IM3 A;  4AZB A;  1TQT A;  3KDR A;  1DC1 A;  3DX0 A;  4R28 A;  2PMR A;  1E1D A;  4E5G A;  2X5C A;  3D2E A;  2EFL A;  1BAM A;  2F1A A;  1HWW A;  4EZN A;  3LMF A;  4KIK A;  2F7O A;  1TQW A;  4E5I A;  5I13 A;  5TKY A;  4F0Q A;  4WPE A;  3F7W A;  3WVG A;  3UIT A;  1OAO A;  3I01 A;  4HYB A;  4OC8 A;  4AWK A;  3DX2 A;  4NPH A;  3CZS A;  3BVV A;  3L3P A;  4R5I A;  3BUQ A;  3EJQ A;  3G9G A;  1GN9 A;  2Z0V A;  3ERC C;  2XI5 A;  2QKW A;  3BUI A;  2D4C A;  4F00 A;  3EBJ A;  2YL5 A;  3WVH A;  3DX1 A;  5JHV A;  3BVT A;  4IWP A;  3CKD A;  4NFZ A;  3BAM A;  4NSW A;  2WYH A;  4BNE A;  3T46 A;  1SU6 A;  2P0J A;  4JWI A;  4R5K A;  5KBP A;  3DVO A;  3RPM A;  2EWF A;  4IW0 A;  2QXL A;  3BVX A;  2YLL A;  4AZ6 A;  3D2F A;  4E5J A;  4AVM A;  4EZV A;  3BUP A;  3DW9 A;  1W9M A;  1URU A;  2Z8Y A;  1D2I A;  2WYI A;  4DYL A;  1X03 A;  4H6I A;  3C7N A;  1I4T A;  3V20 A;  4R5L A;  3I04 A;  2QFF A;  1FZR A;  4F0P A;  2JNS A;  3OHX M;  3L3O M;  2OZN B;  5E84 A;  2PY6 A;  5C5B B;  2GF4 A;  3QNJ A;  2BAM A;  5FDG A;  4ATM A;  1HTY A;  2X3X A;  4CGX A;  3B52 X;  3DDF A;  3BVU A;  4ZI0 A;  4PO2 A;  3HW5 A;  1E2U A;  1JQK A;  3D50 A;  2E52 A;  4H8S A;  3WVP A;  5FIG A;  3SYV A;  3WVI A;  4AVL A;  4EZY A;  1YWM A;  4AWG A;  3HW4 A;  4AZC B;  4AZI A;  2LXY A;  3CZN A;  3D4Z A;  4UDY X;  3DDG A;  4ZHZ A;  2ND0 A;  3LLL A;  1HXK A;  3KAV A;  1DFM A;  2P14 A;  1SU8 A;  3KAW A;  2XI7 A;  2FYV A;  3DYT A;  1OA1 A;  3T49 A;  2FIC A;  2YL9 A;  5EGA A;  3QE6 A;  4EZX A;  2F7R A;  4AVG A;  2ALW A;  3ABH A;  2Q12 A;  4M0M A;  4EZP A;  1M0D A;  4AZC A;  2FOK A;  1KNV A;  3A4K A;  2YI8 A;  3Q84 A;  4IM0 A;  2KHO A;  2C08 A;  2Z0O A;  2PFJ A;  4G6Q A;  2RAI A;  2X3W A;  4IM2 A;  1O7D B;  4FM3 A;  4E3C A;  1DKY A;  2N3K A;  1OA0 A;  4HR1 B;  2X3V A;  4I1Q A;  3VKH A;  3GI7 A;  4AWM A;  1I49 A;  3EJS A;  4JWE A;  2MI7 A;  5FLE X;  1WDZ A;  1MJG A;  1SDO A;  4E5L A;  4HY9 A;  3T4A G;  3T47 A;  1E9V A;  3EJU A;  3BVW A;  1TQS A;  3CVR A;  2JNK A;  4AVQ A;  1QWN A;  4AWF A;  4ZQQ A;  5CL0 A;  5CCY A;  4D8J A;  2GB7 A;  4R5J A;  1I4D A;  1FOK A;  1BHM A;  1SU7 A;  3ER8 C;  4IWO A;  2OO2 A;  3ODH A;  2RT6 A;  3B51 X;  4AKV A;  3DPO A;  4JNE A;  3BUD A;  4R5G A;  4YYL A;  3A98 A;  3D4Y A;  2O0I 1;  2OW7 A;  4FZS A;  3EJP A;  1GNT A;  4AZH A;  4JWD A;  5DES A;  4AZ5 A;  3DPQ A;  3OK8 A;  3I39 X;  3CAE A;  3RV1 A;  3ZED A;  4DCN C;  2EFK A;  2Q13 A;  4UDX X;  3VEB A;  2F1B A;  3RV0 A;  2FQZ A;  4EZU A;  4AZ7 A;  3O3M B;  4JNF A;  2YIV X;  4IWQ A;  3LVT A;  3HW6 A;  4KIK B;  4E5F A;  5C5B A;  2LM0 A;  1Y2O A;  5JHT A;  4EZZ A;  4EZO A;  2F7P A;  3BM3 A;  1TQV A;  3WVK A;  3V21 A;  3DPP A;  3I2W A;  3OWG A;  3PLT A;  3D51 A;  3DPG A;  2D1L A;  1PS3 A;  4JLC A;  2NCZ A;  2ND1 A;  5D9J A;  4JN4 A;  3QNI A;  1ES8 A;  5CGV A;  4FZP A;  3CAZ A;  1VRR A;  4E5E A;  2YKT A;  1LQ7 A;  3BUB A;  1QWU A;  3QWE A;  3MQ6 A;  4B9Q A;  2YIB A;  3D52 A;  5DEB A;  1DKX A;  1SUF A;  1R34 A;  5CZN A;  3N7B A;  5D4G A;  5D2O A;  3B53 X;  2RAK A;  2F18 A;  5FDD A;  4H6H A;  3HAI A;  4EZS A;  2OW6 A;  2OBM A;  1O7D C;  2YIA A;  2OBL A;  3Q0K A;  5D42 A;  1ZYL A;  3QA8 A;  4EZR A;  1CFR A;  3MQY A;  2YLA A;  2YL6 A;  2WIN M;  3EJR A;  1I4L A;  2GAF D;  4HR1 A;  5DBS A; 
#chains in the Genus database with same CATH homology
 5DES A;  4NPH A;  4AWH A;  3DPQ A;  4UDY X;  1GNL A;  3I39 X;  4R5I A;  1DKZ A;  3CAE A;  4EZT A;  4E5H A;  4ZHZ A;  1GN9 A;  3RV1 A;  2ND0 A;  3ZED A;  3ERC C;  3KAV A;  2XI5 A;  1DFM A;  1M0I A;  3FD9 A;  4F00 A;  1SU8 A;  2P14 A;  2EX3 B;  3EBJ A;  3KAW A;  3V1Z A;  2XI7 A;  4UDX X;  3WVH A;  3VEB A;  1OA1 A;  3T49 A;  5JHV A;  4JWC A;  4IWP A;  3RV0 A;  5EGA A;  4NFZ A;  4EZX A;  3BAM A;  3O3N B;  5D8U A;  2FQZ A;  4AVG A;  4EZU A;  4CHC A;  3T46 A;  4M0M A;  1SU6 A;  3O3M B;  4JNF A;  2YIV X;  4IWQ A;  4EZP A;  4F01 A;  4JWI A;  4JL9 A;  1M0D A;  3HW6 A;  1ESG A;  2P0J A;  4KIK B;  4E5F A;  2FOK A;  1KNV A;  3A4K A;  2LM0 A;  4R5K A;  2YI8 A;  3N78 A;  4IM0 A;  2KHO A;  4EZZ A;  4EZO A;  5JHT A;  3BM3 A;  3DVO A;  2PFJ A;  3WVK A;  3V21 A;  3DPP A;  4G6Q A;  3OWG A;  2GA9 D;  2EWF A;  3HW3 A;  4IM2 A;  4IW0 A;  2QXL A;  4FM3 A;  3O3O B;  3DPG A;  4E3C A;  3D2F A;  3VEA A;  4E5J A;  1DKY A;  3T48 A;  2N3K A;  4JLC A;  4EZV A;  3DW9 A;  1OA0 A;  2NCZ A;  1W9M A;  4HR1 B;  4EZQ A;  1U00 A;  4E81 A;  2ND1 A;  2Z8Y A;  1D2I A;  5D9J A;  4JN4 A;  3VKH A;  4CGS A;  2YI9 A;  1ES8 A;  5CGV A;  3GI7 A;  4AWM A;  3ER9 B;  4EZW A;  1VRR A;  4H6I A;  4JWE A;  4E5E A;  5FLE X;  3C7N A;  3MQ6 A;  1MJG A;  1SDO A;  4B9Q A;  1UPX A;  2YIB A;  4E5L A;  4HY9 A;  3V20 A;  4R5L A;  3T4A G;  5DEB A;  1DKX A;  3I04 A;  2QFF A;  3T47 A;  1SUF A;  1FZR A;  1E9V A;  5CZN A;  4F0P A;  3N7B A;  2JNS A;  4IM3 A;  5D4G A;  5D2O A;  3B53 X;  3KDR A;  1DC1 A;  3OHX M;  3L3O M;  4AVQ A;  5FDD A;  4AWF A;  5E84 A;  4R28 A;  4ZQQ A;  2PY6 A;  4H6H A;  5CL0 A;  5CCY A;  1E1D A;  4D8J A;  2X5C A;  3D2E A;  4E5G A;  1BAM A;  2GB7 A;  4R5J A;  3QNJ A;  4EZN A;  4EZS A;  1FOK A;  3LMF A;  4KIK A;  1BHM A;  2BAM A;  1SU7 A;  3ER8 C;  4E5I A;  4IWO A;  5FDG A;  5I13 A;  5TKY A;  3ODH A;  2OBM A;  2YIA A;  4F0Q A;  2OBL A;  2RT6 A;  3B51 X;  4CGX A;  3F7W A;  3B52 X;  3DPO A;  4JNE A;  5D42 A;  4R5G A;  4YYL A;  4ZI0 A;  1ZYL A;  3A98 A;  3QA8 A;  4EZR A;  4PO2 A;  3HW5 A;  1CFR A;  1E2U A;  1JQK A;  3UIT A;  3WVG A;  3MQY A;  2E52 A;  2WIN M;  3WVP A;  5FIG A;  1GNT A;  3WVI A;  1OAO A;  4AVL A;  4EZY A;  4AWG A;  3I01 A;  4HYB A;  2GAF D;  4OC8 A;  4AWK A;  3HW4 A;  4HR1 A;  4JWD A;  5DBS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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