2F1X | Genus

Total Genus 24

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	24
sequence length	142
structure length	137
Chain Sequence	TSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPGGSR

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 137 atoms

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137 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Hydrolase
source organism	Homo sapiens
publication title	Structural Basis of Competitive Recognition of p53 and MDM2 by HAUSP/USP7: Implications for the Regulation of the p53-MDM2 Pathway. pubmed doi rcsb
molecule keywords	HAUSP/USP7
total genus	24
structure length	137
sequence length	142
chains with identical sequence	B
ec nomenclature	ec 3.4.19.12: Ubiquitinyl hydrolase 1.
pdb deposition date	2005-11-15

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00917	MATH	MATH domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.60.210.10	Mainly Beta	Sandwich	Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A	Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A	2f1xA00

1CA9A 1CZZA 2CR2A 4JJQA 1KZZA 1ZMSA 3IVQA 4CA1A 1L0AA 1RF3A 1F3VB 2F1ZA 2FOPA 3HQIA 4I7BA 1FLLA 2GKWA 5H9MA 4K8UA 2XXNA 2F1YA 3MQRA 1D0JA 2F1WA 1FLKA 2A25A 3IVVA 1K2FA 1YZEA 3HQMA 3HU6A 3HQLA 4O1VA 3HSVA 4M4EA 4X3GA 1LB5A 3MQSC 1LB4A 2FOJA 4GJHA 4GWNA 2FOOA 4Z8MA 1CA4A 4I7DA 1D00A 3HQHA 3IVBA 4I7CA 4KG9A 1QSCA 5E1TA 1D01A 4GHUA 1D0AA 4GWMA 3ZJBA 1YY6A 1LB6A 2AN6A 2F1XA 1CZYA 4YSIA 4C9ZA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 1CA9 A;  1CZZ A;  2CR2 A;  4JJQ A;  1KZZ A;  1ZMS A;  3IVQ A;  4CA1 A;  1L0A A;  1RF3 A;  1F3V B;  2F1Z A;  2FOP A;  3HQI A;  4I7B A;  1FLL A;  2GKW A;  5H9M A;  4K8U A;  2XXN A;  2F1Y A;  3MQR A;  1D0J A;  2F1W A;  1FLK A;  2A25 A;  3IVV A;  1K2F A;  1YZE A;  3HQM A;  3HU6 A;  3HQL A;  4O1V A;  3HSV A;  4M4E A;  4X3G A;  1LB5 A;  3MQS C;  1LB4 A;  2FOJ A;  4GJH A;  4GWN A;  2FOO A;  4Z8M A;  1CA4 A;  4I7D A;  1D00 A;  3HQH A;  3IVB A;  4I7C A;  4KG9 A;  1QSC A;  5E1T A;  1D01 A;  4GHU A;  1D0A A;  4GWM A;  3ZJB A;  1YY6 A;  1LB6 A;  2AN6 A;  2F1X A;  1CZY A;  4YSI A;  4C9Z A; 
#chains in the Genus database with same CATH topology
 1CA9 A;  1CZZ A;  2CR2 A;  4JJQ A;  1KZZ A;  1ZMS A;  3IVQ A;  4CA1 A;  1L0A A;  1RF3 A;  1F3V B;  2F1Z A;  2FOP A;  3HQI A;  4I7B A;  1FLL A;  2GKW A;  5H9M A;  4K8U A;  2XXN A;  2F1Y A;  3MQR A;  1D0J A;  2F1W A;  1FLK A;  2A25 A;  3IVV A;  1K2F A;  1YZE A;  3HQM A;  3HU6 A;  3HQL A;  4O1V A;  3HSV A;  4M4E A;  4X3G A;  1LB5 A;  3MQS C;  1LB4 A;  2FOJ A;  4GJH A;  4GWN A;  2FOO A;  4Z8M A;  1CA4 A;  4I7D A;  1D00 A;  3HQH A;  3IVB A;  4I7C A;  4KG9 A;  1QSC A;  5E1T A;  1D01 A;  4GHU A;  1D0A A;  4GWM A;  3ZJB A;  1YY6 A;  1LB6 A;  2AN6 A;  2F1X A;  1CZY A;  4YSI A;  4C9Z A; 
#chains in the Genus database with same CATH homology
 1CA9 A;  1CZZ A;  2CR2 A;  4JJQ A;  1KZZ A;  1ZMS A;  3IVQ A;  4CA1 A;  1L0A A;  1RF3 A;  1F3V B;  2F1Z A;  2FOP A;  3HQI A;  4I7B A;  1FLL A;  2GKW A;  5H9M A;  4K8U A;  2XXN A;  2F1Y A;  3MQR A;  1D0J A;  2F1W A;  1FLK A;  2A25 A;  3IVV A;  1K2F A;  1YZE A;  3HQM A;  3HU6 A;  3HQL A;  4O1V A;  3HSV A;  4M4E A;  4X3G A;  1LB5 A;  3MQS C;  1LB4 A;  2FOJ A;  4GJH A;  4GWN A;  2FOO A;  4Z8M A;  1CA4 A;  4I7D A;  1D00 A;  3HQH A;  3IVB A;  4I7C A;  4KG9 A;  1QSC A;  5E1T A;  1D01 A;  4GHU A;  1D0A A;  4GWM A;  3ZJB A;  1YY6 A;  1LB6 A;  2AN6 A;  2F1X A;  1CZY A;  4YSI A;  4C9Z A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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2F1XA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations