2FOJA

The crystal structure of the n-terminal domain of hausp/usp7 complexed with p53 peptide 364-367
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
143
structure length
137
Chain Sequence
TSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
source organism Homo sapiens
publication title Molecular recognition of p53 and MDM2 by USP7/HAUSP
pubmed doi rcsb
molecule keywords Ubiquitin carboxyl-terminal hydrolase 7
total genus 23
structure length 137
sequence length 143
ec nomenclature ec 3.4.19.12: Ubiquitinyl hydrolase 1.
pdb deposition date 2006-01-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00917 MATH MATH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.210.10 Mainly Beta Sandwich Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A 2fojA00
4O1VA 4X3GA 5H9MA 4I7CA 1K2FA 2FOOA 4CA1A 4C9ZA 2FOPA 4GWMA 1CZYA 1D0JA 3HQMA 1D00A 1L0AA 1D01A 4M4EA 2F1ZA 2AN6A 2CR2A 1FLLA 1RF3A 1CZZA 1D0AA 4GHUA 4KG9A 4I7BA 1CA9A 1LB6A 2F1YA 3HQLA 3HQIA 3MQSC 1QSCA 4Z8MA 3ZJBA 3IVQA 4I7DA 5E1TA 2F1XA 3HQHA 1F3VB 2GKWA 1CA4A 3MQRA 1ZMSA 1YY6A 2FOJA 3IVBA 1KZZA 4YSIA 1YZEA 3HSVA 4GWNA 1FLKA 1LB4A 4K8UA 3IVVA 2A25A 1LB5A 4GJHA 4JJQA 2XXNA 3HU6A 2F1WA
chains in the Genus database with same CATH superfamily
4O1VA 4X3GA 5H9MA 4I7CA 1K2FA 2FOOA 4CA1A 4C9ZA 2FOPA 4GWMA 1CZYA 1D0JA 3HQMA 1D00A 1L0AA 1D01A 4M4EA 2F1ZA 2AN6A 2CR2A 1FLLA 1RF3A 1CZZA 1D0AA 4GHUA 4KG9A 4I7BA 1CA9A 1LB6A 2F1YA 3HQLA 3HQIA 3MQSC 1QSCA 4Z8MA 3ZJBA 3IVQA 4I7DA 5E1TA 2F1XA 3HQHA 1F3VB 2GKWA 1CA4A 3MQRA 1ZMSA 1YY6A 2FOJA 3IVBA 1KZZA 4YSIA 1YZEA 3HSVA 4GWNA 1FLKA 1LB4A 4K8UA 3IVVA 2A25A 1LB5A 4GJHA 4JJQA 2XXNA 3HU6A 2F1WA
chains in the Genus database with same CATH topology
4O1VA 4X3GA 5H9MA 4I7CA 1K2FA 2FOOA 4CA1A 4C9ZA 2FOPA 4GWMA 1CZYA 1D0JA 3HQMA 1D00A 1L0AA 1D01A 4M4EA 2F1ZA 2AN6A 2CR2A 1FLLA 1RF3A 1CZZA 1D0AA 4GHUA 4KG9A 4I7BA 1CA9A 1LB6A 2F1YA 3HQLA 3HQIA 3MQSC 1QSCA 4Z8MA 3ZJBA 3IVQA 4I7DA 5E1TA 2F1XA 3HQHA 1F3VB 2GKWA 1CA4A 3MQRA 1ZMSA 1YY6A 2FOJA 3IVBA 1KZZA 4YSIA 1YZEA 3HSVA 4GWNA 1FLKA 1LB4A 4K8UA 3IVVA 2A25A 1LB5A 4GJHA 4JJQA 2XXNA 3HU6A 2F1WA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4O1V A;  4X3G A;  5H9M A;  4I7C A;  1K2F A;  2FOO A;  4CA1 A;  4C9Z A;  2FOP A;  4GWM A;  1CZY A;  1D0J A;  3HQM A;  1D00 A;  1L0A A;  1D01 A;  4M4E A;  2F1Z A;  2AN6 A;  2CR2 A;  1FLL A;  1RF3 A;  1CZZ A;  1D0A A;  4GHU A;  4KG9 A;  4I7B A;  1CA9 A;  1LB6 A;  2F1Y A;  3HQL A;  3HQI A;  3MQS C;  1QSC A;  4Z8M A;  3ZJB A;  3IVQ A;  4I7D A;  5E1T A;  2F1X A;  3HQH A;  1F3V B;  2GKW A;  1CA4 A;  3MQR A;  1ZMS A;  1YY6 A;  2FOJ A;  3IVB A;  1KZZ A;  4YSI A;  1YZE A;  3HSV A;  4GWN A;  1FLK A;  1LB4 A;  4K8U A;  3IVV A;  2A25 A;  1LB5 A;  4GJH A;  4JJQ A;  2XXN A;  3HU6 A;  2F1W A; 
#chains in the Genus database with same CATH topology
 4O1V A;  4X3G A;  5H9M A;  4I7C A;  1K2F A;  2FOO A;  4CA1 A;  4C9Z A;  2FOP A;  4GWM A;  1CZY A;  1D0J A;  3HQM A;  1D00 A;  1L0A A;  1D01 A;  4M4E A;  2F1Z A;  2AN6 A;  2CR2 A;  1FLL A;  1RF3 A;  1CZZ A;  1D0A A;  4GHU A;  4KG9 A;  4I7B A;  1CA9 A;  1LB6 A;  2F1Y A;  3HQL A;  3HQI A;  3MQS C;  1QSC A;  4Z8M A;  3ZJB A;  3IVQ A;  4I7D A;  5E1T A;  2F1X A;  3HQH A;  1F3V B;  2GKW A;  1CA4 A;  3MQR A;  1ZMS A;  1YY6 A;  2FOJ A;  3IVB A;  1KZZ A;  4YSI A;  1YZE A;  3HSV A;  4GWN A;  1FLK A;  1LB4 A;  4K8U A;  3IVV A;  2A25 A;  1LB5 A;  4GJH A;  4JJQ A;  2XXN A;  3HU6 A;  2F1W A; 
#chains in the Genus database with same CATH homology
 4O1V A;  4X3G A;  5H9M A;  4I7C A;  1K2F A;  2FOO A;  4CA1 A;  4C9Z A;  2FOP A;  4GWM A;  1CZY A;  1D0J A;  3HQM A;  1D00 A;  1L0A A;  1D01 A;  4M4E A;  2F1Z A;  2AN6 A;  2CR2 A;  1FLL A;  1RF3 A;  1CZZ A;  1D0A A;  4GHU A;  4KG9 A;  4I7B A;  1CA9 A;  1LB6 A;  2F1Y A;  3HQL A;  3HQI A;  3MQS C;  1QSC A;  4Z8M A;  3ZJB A;  3IVQ A;  4I7D A;  5E1T A;  2F1X A;  3HQH A;  1F3V B;  2GKW A;  1CA4 A;  3MQR A;  1ZMS A;  1YY6 A;  2FOJ A;  3IVB A;  1KZZ A;  4YSI A;  1YZE A;  3HSV A;  4GWN A;  1FLK A;  1LB4 A;  4K8U A;  3IVV A;  2A25 A;  1LB5 A;  4GJH A;  4JJQ A;  2XXN A;  3HU6 A;  2F1W A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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