2FOOA

The crystal structure of the n-terminal domain of hausp/usp7 complexed with p53 peptide 359-362
Total Genus 24

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
143
structure length
137
Chain Sequence
TSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAW

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
EMPTYTIV3 (103-112)S6 (131-140)TI1 (63-66)S3 (90-92)S1 (68-75)S2 (85-86)TI2 (122-125)TIV6 (120-123)TIV4 (104-113)S5 (114-121)3H1 (78-80)TIV2 (91-94)S4 (95-104)TIV7 (127-130)TIV1 (75-78)Updating...
connected with : NaN
molecule tags Hydrolase
source organism Homo sapiens
publication title Molecular recognition of p53 and MDM2 by USP7/HAUSP
pubmed doi rcsb
molecule keywords Ubiquitin carboxyl-terminal hydrolase 7
total genus 24
structure length 137
sequence length 143
ec nomenclature ec 3.4.19.12: Ubiquitinyl hydrolase 1.
pdb deposition date 2006-01-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00917 MATH MATH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.210.10 Mainly Beta Sandwich Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A 2fooA00
2F1XA 2FOPA 4I7CA 4I7DA 4JJQA 4O1VA 4CA1A 2XXNA 1CA4A 3IVQA 2F1WA 2GKWA 1KZZA 4Z8MA 3HU6A 3HQHA 4GJHA 1FLKA 2CR2A 1D0JA 1QSCA 1D01A 1LB4A 3MQRA 1L0AA 4K8UA 5E1TA 2AN6A 1CZYA 2F1ZA 4GWMA 4M4EA 1ZMSA 4C9ZA 1LB6A 1YY6A 3ZJBA 1F3VB 2F1YA 1CZZA 3HQIA 4I7BA 3MQSC 1D00A 2A25A 1RF3A 4X3GA 4YSIA 1CA9A 1FLLA 1LB5A 1K2FA 3IVBA 2FOJA 3HSVA 2FOOA 3HQLA 4GWNA 5H9MA 3IVVA 1YZEA 3HQMA 1D0AA 4GHUA 4KG9A
chains in the Genus database with same CATH superfamily
2F1XA 2FOPA 4I7CA 4I7DA 4JJQA 4O1VA 4CA1A 2XXNA 1CA4A 3IVQA 2F1WA 2GKWA 1KZZA 4Z8MA 3HU6A 3HQHA 4GJHA 1FLKA 2CR2A 1D0JA 1QSCA 1D01A 1LB4A 3MQRA 1L0AA 4K8UA 5E1TA 2AN6A 1CZYA 2F1ZA 4GWMA 4M4EA 1ZMSA 4C9ZA 1LB6A 1YY6A 3ZJBA 1F3VB 2F1YA 1CZZA 3HQIA 4I7BA 3MQSC 1D00A 2A25A 1RF3A 4X3GA 4YSIA 1CA9A 1FLLA 1LB5A 1K2FA 3IVBA 2FOJA 3HSVA 2FOOA 3HQLA 4GWNA 5H9MA 3IVVA 1YZEA 3HQMA 1D0AA 4GHUA 4KG9A
chains in the Genus database with same CATH topology
2F1XA 2FOPA 4I7CA 4I7DA 4JJQA 4O1VA 4CA1A 2XXNA 1CA4A 3IVQA 2F1WA 2GKWA 1KZZA 4Z8MA 3HU6A 3HQHA 4GJHA 1FLKA 2CR2A 1D0JA 1QSCA 1D01A 1LB4A 3MQRA 1L0AA 4K8UA 5E1TA 2AN6A 1CZYA 2F1ZA 4GWMA 4M4EA 1ZMSA 4C9ZA 1LB6A 1YY6A 3ZJBA 1F3VB 2F1YA 1CZZA 3HQIA 4I7BA 3MQSC 1D00A 2A25A 1RF3A 4X3GA 4YSIA 1CA9A 1FLLA 1LB5A 1K2FA 3IVBA 2FOJA 3HSVA 2FOOA 3HQLA 4GWNA 5H9MA 3IVVA 1YZEA 3HQMA 1D0AA 4GHUA 4KG9A
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2F1X A;  2FOP A;  4I7C A;  4I7D A;  4JJQ A;  4O1V A;  4CA1 A;  2XXN A;  1CA4 A;  3IVQ A;  2F1W A;  2GKW A;  1KZZ A;  4Z8M A;  3HU6 A;  3HQH A;  4GJH A;  1FLK A;  2CR2 A;  1D0J A;  1QSC A;  1D01 A;  1LB4 A;  3MQR A;  1L0A A;  4K8U A;  5E1T A;  2AN6 A;  1CZY A;  2F1Z A;  4GWM A;  4M4E A;  1ZMS A;  4C9Z A;  1LB6 A;  1YY6 A;  3ZJB A;  1F3V B;  2F1Y A;  1CZZ A;  3HQI A;  4I7B A;  3MQS C;  1D00 A;  2A25 A;  1RF3 A;  4X3G A;  4YSI A;  1CA9 A;  1FLL A;  1LB5 A;  1K2F A;  3IVB A;  2FOJ A;  3HSV A;  2FOO A;  3HQL A;  4GWN A;  5H9M A;  3IVV A;  1YZE A;  3HQM A;  1D0A A;  4GHU A;  4KG9 A; 
#chains in the Genus database with same CATH topology
 2F1X A;  2FOP A;  4I7C A;  4I7D A;  4JJQ A;  4O1V A;  4CA1 A;  2XXN A;  1CA4 A;  3IVQ A;  2F1W A;  2GKW A;  1KZZ A;  4Z8M A;  3HU6 A;  3HQH A;  4GJH A;  1FLK A;  2CR2 A;  1D0J A;  1QSC A;  1D01 A;  1LB4 A;  3MQR A;  1L0A A;  4K8U A;  5E1T A;  2AN6 A;  1CZY A;  2F1Z A;  4GWM A;  4M4E A;  1ZMS A;  4C9Z A;  1LB6 A;  1YY6 A;  3ZJB A;  1F3V B;  2F1Y A;  1CZZ A;  3HQI A;  4I7B A;  3MQS C;  1D00 A;  2A25 A;  1RF3 A;  4X3G A;  4YSI A;  1CA9 A;  1FLL A;  1LB5 A;  1K2F A;  3IVB A;  2FOJ A;  3HSV A;  2FOO A;  3HQL A;  4GWN A;  5H9M A;  3IVV A;  1YZE A;  3HQM A;  1D0A A;  4GHU A;  4KG9 A; 
#chains in the Genus database with same CATH homology
 2F1X A;  2FOP A;  4I7C A;  4I7D A;  4JJQ A;  4O1V A;  4CA1 A;  2XXN A;  1CA4 A;  3IVQ A;  2F1W A;  2GKW A;  1KZZ A;  4Z8M A;  3HU6 A;  3HQH A;  4GJH A;  1FLK A;  2CR2 A;  1D0J A;  1QSC A;  1D01 A;  1LB4 A;  3MQR A;  1L0A A;  4K8U A;  5E1T A;  2AN6 A;  1CZY A;  2F1Z A;  4GWM A;  4M4E A;  1ZMS A;  4C9Z A;  1LB6 A;  1YY6 A;  3ZJB A;  1F3V B;  2F1Y A;  1CZZ A;  3HQI A;  4I7B A;  3MQS C;  1D00 A;  2A25 A;  1RF3 A;  4X3G A;  4YSI A;  1CA9 A;  1FLL A;  1LB5 A;  1K2F A;  3IVB A;  2FOJ A;  3HSV A;  2FOO A;  3HQL A;  4GWN A;  5H9M A;  3IVV A;  1YZE A;  3HQM A;  1D0A A;  4GHU A;  4KG9 A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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