2GKW | Genus

Total Genus 48

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	48
sequence length	192
structure length	192
Chain Sequence	NTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIVDTSDLPDP

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Apoptosis
source organism	Homo sapiens
publication title	Key molecular contacts promote recognition of the BAFF receptor by TNF receptor-associated factor 3: implications for intracellular signaling regulation. pubmed rcsb
molecule keywords	TNF receptor-associated factor 3
total genus	48
structure length	192
sequence length	192
ec nomenclature	ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date	2006-04-03

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.60.210.10	Mainly Beta	Sandwich	Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A	Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A	2gkwA00

1LB4A 3MQSC 3HQLA 1CZYA 3HQMA 4C9ZA 4K8UA 4KG9A 1FLKA 2FOPA 2FOOA 2CR2A 4O1VA 4GJHA 1RF3A 1D00A 3HSVA 4GWMA 4Z8MA 5E1TA 1CA9A 2F1YA 1KZZA 4X3GA 4JJQA 2XXNA 3HQHA 1LB5A 1D01A 1CA4A 1ZMSA 3IVQA 4I7CA 4YSIA 3MQRA 2A25A 2GKWA 2F1WA 1LB6A 1CZZA 2AN6A 2F1ZA 2FOJA 3IVBA 4GWNA 4M4EA 1QSCA 4GHUA 1K2FA 1L0AA 3HQIA 1YY6A 5H9MA 4CA1A 1D0AA 3IVVA 1YZEA 4I7DA 1FLLA 2F1XA 4I7BA 3ZJBA 3HU6A 1F3VB 1D0JA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 1LB4 A;  3MQS C;  3HQL A;  1CZY A;  3HQM A;  4C9Z A;  4K8U A;  4KG9 A;  1FLK A;  2FOP A;  2FOO A;  2CR2 A;  4O1V A;  4GJH A;  1RF3 A;  1D00 A;  3HSV A;  4GWM A;  4Z8M A;  5E1T A;  1CA9 A;  2F1Y A;  1KZZ A;  4X3G A;  4JJQ A;  2XXN A;  3HQH A;  1LB5 A;  1D01 A;  1CA4 A;  1ZMS A;  3IVQ A;  4I7C A;  4YSI A;  3MQR A;  2A25 A;  2GKW A;  2F1W A;  1LB6 A;  1CZZ A;  2AN6 A;  2F1Z A;  2FOJ A;  3IVB A;  4GWN A;  4M4E A;  1QSC A;  4GHU A;  1K2F A;  1L0A A;  3HQI A;  1YY6 A;  5H9M A;  4CA1 A;  1D0A A;  3IVV A;  1YZE A;  4I7D A;  1FLL A;  2F1X A;  4I7B A;  3ZJB A;  3HU6 A;  1F3V B;  1D0J A; 
#chains in the Genus database with same CATH topology
 1LB4 A;  3MQS C;  3HQL A;  1CZY A;  3HQM A;  4C9Z A;  4K8U A;  4KG9 A;  1FLK A;  2FOP A;  2FOO A;  2CR2 A;  4O1V A;  4GJH A;  1RF3 A;  1D00 A;  3HSV A;  4GWM A;  4Z8M A;  5E1T A;  1CA9 A;  2F1Y A;  1KZZ A;  4X3G A;  4JJQ A;  2XXN A;  3HQH A;  1LB5 A;  1D01 A;  1CA4 A;  1ZMS A;  3IVQ A;  4I7C A;  4YSI A;  3MQR A;  2A25 A;  2GKW A;  2F1W A;  1LB6 A;  1CZZ A;  2AN6 A;  2F1Z A;  2FOJ A;  3IVB A;  4GWN A;  4M4E A;  1QSC A;  4GHU A;  1K2F A;  1L0A A;  3HQI A;  1YY6 A;  5H9M A;  4CA1 A;  1D0A A;  3IVV A;  1YZE A;  4I7D A;  1FLL A;  2F1X A;  4I7B A;  3ZJB A;  3HU6 A;  1F3V B;  1D0J A; 
#chains in the Genus database with same CATH homology
 1LB4 A;  3MQS C;  3HQL A;  1CZY A;  3HQM A;  4C9Z A;  4K8U A;  4KG9 A;  1FLK A;  2FOP A;  2FOO A;  2CR2 A;  4O1V A;  4GJH A;  1RF3 A;  1D00 A;  3HSV A;  4GWM A;  4Z8M A;  5E1T A;  1CA9 A;  2F1Y A;  1KZZ A;  4X3G A;  4JJQ A;  2XXN A;  3HQH A;  1LB5 A;  1D01 A;  1CA4 A;  1ZMS A;  3IVQ A;  4I7C A;  4YSI A;  3MQR A;  2A25 A;  2GKW A;  2F1W A;  1LB6 A;  1CZZ A;  2AN6 A;  2F1Z A;  2FOJ A;  3IVB A;  4GWN A;  4M4E A;  1QSC A;  4GHU A;  1K2F A;  1L0A A;  3HQI A;  1YY6 A;  5H9M A;  4CA1 A;  1D0A A;  3IVV A;  1YZE A;  4I7D A;  1FLL A;  2F1X A;  4I7B A;  3ZJB A;  3HU6 A;  1F3V B;  1D0J A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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2GKWA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization