2JBYA

A viral protein unexpectedly mimics the structure and function of pro- survival bcl-2
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
127
structure length
127
Chain Sequence
MSRLKTAVYDYLNDVDITECTEMDLLCQLSNCCDFINETYAKNYDTLYDIMERDILSYNIVNIKNTLTFALRDASPSVKLATLTLLASVIKKLNKIQHTDAAMFSEVIDGIVAEEQQVIGFIQKKCK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A structural viral mimic of prosurvival Bcl-2: a pivotal role for sequestering proapoptotic Bax and Bak.
pubmed doi rcsb
molecule tags Apoptosis
source organism Myxoma virus
molecule keywords M11L PROTEIN
total genus 43
structure length 127
sequence length 127
ec nomenclature
pdb deposition date 2006-12-14
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.437.40 Mainly Alpha Orthogonal Bundle Apoptosis Regulator Bcl-x Apoptosis Regulator Bcl-x 2jbyA00
2JBYA 2VTYA 4UF2A 4D2LA 4UF3A 4D2MA 2JBXA 2O42A 4UF1A
chains in the Genus database with same CATH superfamily
4BDUA 4MI8A 4ZIHA 1ZY3A 2UXEA 2ME8A 2K36A 2O21A 1G5JA 1LXLA 2A5YA 2K7WA 2JCNA 5FDOA 4ZIGA 4UF3A 1R2EA 3D7VA 2O2FA 4ZBFA 5IF4A 2KBWA 3PK1A 4S0PA 1F16A 2VOHA 1YSGA 2WH6A 3WIXA 2IMSA 3MK8A 1MAZA 2MHSA 3IO9A 2O2MA 1R2GA 1R2IA 1TY4A 3I1HA 4HW2A 2LR1A 3KZ0A 1YSWA 4D2MA 4HW3A 2JBXA 1YSNA 2NL9A 1Q59A 5FMIA 4BBBA 4OQ6A 1R2HA 2BZWA 2KUAA 3IHEA 2YV6A 1R2DA 4YK9A 3IIGA 2W3LA 2O2NA 2NLAA 2IMTA 5C3FA 2VTYA 2ROCA 5FC4A 4B4SA 2VOGA 3KJ1A 2BIDA 1PQ0A 1WSXA 1BXLA 2VOFA 4M0SA 4S0OA 2O42A 4OYDA 2VVXA 1GJHA 3KJ0A 2ABOA 5JSBA 1K3KA 3IIHA 3QBRA 4ZEQA 2O22A 4QNQA 2PQKA 3WIYA 2M5BA 2VM6A 5KTGA 4ZIFA 4BBDA 2JBYA 4ZBIA 4BD8A 1YSIA 4U2UA 1MK3A 3IHCA 4OQ5A 4BD6A 4ZIEA 4LQKA 2V6QA 4UF2A 4YJ4A 3KJ2A 3CVAX 5FDRA 2XA0A 5C6HA 1AF3A 4U2VA 4BD7A 2MEJA 1OHUA 4BPJA 4K5BC 4G35A 5IEZA 2VVWA 2RODA 3ILCA 3IHDA 3MQPA 4HW4A 2I39A 2VVYA 2XPXA 4UF1A 4BD2A 3DVUA 4D2LA 4BBCA 4ZIIA 4BPIA 1DDBA 2B48A 3JRVA 3BL2A 5KU9A 1G5MA 4WMRA 2VOIA 1PQ1A 4QVXA 1O0LA 2JM6B
chains in the Genus database with same CATH topology
2UXEA 4M0SA 2O42A 2K36A 2VVXA 2VVWA 4D2MA 4UF3A 2JBXA 2I39A 4BBBA 2VVYA 4UF1A 4BBDA 2JBYA 4D2LA 4BBCA 3JRVA 4LQKA 2VTYA 4UF2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JBY A;  2VTY A;  4UF2 A;  4D2L A;  4UF3 A;  4D2M A;  2JBX A;  2O42 A;  4UF1 A; 
#chains in the Genus database with same CATH topology
 4BDU A;  4MI8 A;  4ZIH A;  1ZY3 A;  2UXE A;  2ME8 A;  2K36 A;  2O21 A;  1G5J A;  1LXL A;  2A5Y A;  2K7W A;  2JCN A;  5FDO A;  4ZIG A;  4UF3 A;  1R2E A;  3D7V A;  2O2F A;  4ZBF A;  5IF4 A;  2KBW A;  3PK1 A;  4S0P A;  1F16 A;  2VOH A;  1YSG A;  2WH6 A;  3WIX A;  2IMS A;  3MK8 A;  1MAZ A;  2MHS A;  3IO9 A;  2O2M A;  1R2G A;  1R2I A;  1TY4 A;  3I1H A;  4HW2 A;  2LR1 A;  3KZ0 A;  1YSW A;  4D2M A;  4HW3 A;  2JBX A;  1YSN A;  2NL9 A;  1Q59 A;  5FMI A;  4BBB A;  4OQ6 A;  1R2H A;  2BZW A;  2KUA A;  3IHE A;  2YV6 A;  1R2D A;  4YK9 A;  3IIG A;  2W3L A;  2O2N A;  2NLA A;  2IMT A;  5C3F A;  2VTY A;  2ROC A;  5FC4 A;  4B4S A;  2VOG A;  3KJ1 A;  2BID A;  1PQ0 A;  1WSX A;  1BXL A;  2VOF A;  4M0S A;  4S0O A;  2O42 A;  4OYD A;  2VVX A;  1GJH A;  3KJ0 A;  2ABO A;  5JSB A;  1K3K A;  3IIH A;  3QBR A;  4ZEQ A;  2O22 A;  4QNQ A;  2PQK A;  3WIY A;  2M5B A;  2VM6 A;  5KTG A;  4ZIF A;  4BBD A;  2JBY A;  4ZBI A;  4BD8 A;  1YSI A;  4U2U A;  1MK3 A;  3IHC A;  4OQ5 A;  4BD6 A;  4ZIE A;  4LQK A;  2V6Q A;  4UF2 A;  4YJ4 A;  3KJ2 A;  3CVA X;  5FDR A;  2XA0 A;  5C6H A;  1AF3 A;  4U2V A;  4BD7 A;  2MEJ A;  1OHU A;  4BPJ A;  4K5B C;  4G35 A;  5IEZ A;  2VVW A;  2ROD A;  3ILC A;  3IHD A;  3MQP A;  4HW4 A;  2I39 A;  2VVY A;  2XPX A;  4UF1 A;  4BD2 A;  3DVU A;  4D2L A;  4BBC A;  4ZII A;  4BPI A;  1DDB A;  2B48 A;  3JRV A;  3BL2 A;  5KU9 A;  1G5M A;  4WMR A;  2VOI A;  1PQ1 A;  4QVX A;  1O0L A;  2JM6 B; 
#chains in the Genus database with same CATH homology
 2UXE A;  4M0S A;  2O42 A;  2K36 A;  2VVX A;  2VVW A;  4D2M A;  4UF3 A;  2JBX A;  2I39 A;  4BBB A;  2VVY A;  4UF1 A;  4BBD A;  2JBY A;  4D2L A;  4BBC A;  3JRV A;  4LQK A;  2VTY A;  4UF2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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