2JBYA

A viral protein unexpectedly mimics the structure and function of pro- survival bcl-2
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
127
structure length
127
Chain Sequence
MSRLKTAVYDYLNDVDITECTEMDLLCQLSNCCDFINETYAKNYDTLYDIMERDILSYNIVNIKNTLTFALRDASPSVKLATLTLLASVIKKLNKIQHTDAAMFSEVIDGIVAEEQQVIGFIQKKCK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A structural viral mimic of prosurvival Bcl-2: a pivotal role for sequestering proapoptotic Bax and Bak.
pubmed doi rcsb
molecule tags Apoptosis
source organism Myxoma virus
molecule keywords M11L PROTEIN
total genus 43
structure length 127
sequence length 127
ec nomenclature
pdb deposition date 2006-12-14
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.437.40 Mainly Alpha Orthogonal Bundle Apoptosis Regulator Bcl-x Apoptosis Regulator Bcl-x 2jbyA00
2VTYA 4UF2A 2JBXA 4D2MA 2O42A 4UF3A 4D2LA 2JBYA 4UF1A
chains in the Genus database with same CATH superfamily
1O0LA 2NL9A 4BBBA 1R2IA 1AF3A 2VOGA 2VOHA 2UXEA 1R2DA 2O21A 4BD2A 4MI8A 5C3FA 4ZEQA 1PQ1A 1WSXA 2RODA 4BD7A 4S0OA 3BL2A 2ABOA 3MQPA 2M5BA 2JBXA 3IHDA 4ZIFA 4OQ6A 1G5MA 3I1HA 2KBWA 5JSBA 2NLAA 3IHEA 1YSGA 2WH6A 4BDUA 1R2HA 3KZ0A 4G35A 4BD6A 4YK9A 2ROCA 4QVXA 2O2NA 5FDRA 2MEJA 4UF1A 4ZIHA 1TY4A 4ZIEA 3IO9A 4HW2A 4BBDA 1ZY3A 5IF4A 2JM6B 2W3LA 2BZWA 2A5YA 3PK1A 2XPXA 2I39A 2O42A 4U2UA 3WIYA 5C6HA 4OYDA 2VVWA 4B4SA 1MAZA 3JRVA 4D2MA 2BIDA 1R2GA 4LQKA 2KUAA 4UF2A 1YSWA 2MHSA 3ILCA 3QBRA 5KTGA 1Q59A 1DDBA 5FC4A 1G5JA 3IIGA 2O22A 3KJ2A 5KU9A 1BXLA 2VTYA 1PQ0A 1F16A 2B48A 4D2LA 4HW3A 2JBYA 2K36A 2ME8A 2YV6A 1LXLA 1K3KA 1YSIA 1MK3A 4WMRA 2IMSA 2VM6A 2VVXA 4ZBFA 2O2FA 4HW4A 2XA0A 4BBCA 2IMTA 1OHUA 3DVUA 4BPIA 2VOFA 4UF3A 4BPJA 2VVYA 3IIHA 3WIXA 3KJ0A 1GJHA 4OQ5A 2LR1A 4S0PA 5FMIA 4U2VA 1R2EA 5FDOA 3D7VA 3IHCA 3KJ1A 2K7WA 3CVAX 4K5BC 2PQKA 4ZBIA 4ZIGA 2O2MA 4YJ4A 1YSNA 2V6QA 2VOIA 2JCNA 4ZIIA 3MK8A 5IEZA 4M0SA 4QNQA 4BD8A
chains in the Genus database with same CATH topology
2VVYA 4BBBA 2UXEA 4UF1A 2VTYA 4BBDA 2JBXA 4D2LA 2JBYA 2K36A 2I39A 2O42A 2VVXA 2VVWA 4BBCA 3JRVA 4D2MA 4UF3A 4M0SA 4LQKA 4UF2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2VTY A;  4UF2 A;  2JBX A;  4D2M A;  2O42 A;  4UF3 A;  4D2L A;  2JBY A;  4UF1 A; 
#chains in the Genus database with same CATH topology
 1O0L A;  2NL9 A;  4BBB A;  1R2I A;  1AF3 A;  2VOG A;  2VOH A;  2UXE A;  1R2D A;  2O21 A;  4BD2 A;  4MI8 A;  5C3F A;  4ZEQ A;  1PQ1 A;  1WSX A;  2ROD A;  4BD7 A;  4S0O A;  3BL2 A;  2ABO A;  3MQP A;  2M5B A;  2JBX A;  3IHD A;  4ZIF A;  4OQ6 A;  1G5M A;  3I1H A;  2KBW A;  5JSB A;  2NLA A;  3IHE A;  1YSG A;  2WH6 A;  4BDU A;  1R2H A;  3KZ0 A;  4G35 A;  4BD6 A;  4YK9 A;  2ROC A;  4QVX A;  2O2N A;  5FDR A;  2MEJ A;  4UF1 A;  4ZIH A;  1TY4 A;  4ZIE A;  3IO9 A;  4HW2 A;  4BBD A;  1ZY3 A;  5IF4 A;  2JM6 B;  2W3L A;  2BZW A;  2A5Y A;  3PK1 A;  2XPX A;  2I39 A;  2O42 A;  4U2U A;  3WIY A;  5C6H A;  4OYD A;  2VVW A;  4B4S A;  1MAZ A;  3JRV A;  4D2M A;  2BID A;  1R2G A;  4LQK A;  2KUA A;  4UF2 A;  1YSW A;  2MHS A;  3ILC A;  3QBR A;  5KTG A;  1Q59 A;  1DDB A;  5FC4 A;  1G5J A;  3IIG A;  2O22 A;  3KJ2 A;  5KU9 A;  1BXL A;  2VTY A;  1PQ0 A;  1F16 A;  2B48 A;  4D2L A;  4HW3 A;  2JBY A;  2K36 A;  2ME8 A;  2YV6 A;  1LXL A;  1K3K A;  1YSI A;  1MK3 A;  4WMR A;  2IMS A;  2VM6 A;  2VVX A;  4ZBF A;  2O2F A;  4HW4 A;  2XA0 A;  4BBC A;  2IMT A;  1OHU A;  3DVU A;  4BPI A;  2VOF A;  4UF3 A;  4BPJ A;  2VVY A;  3IIH A;  3WIX A;  3KJ0 A;  1GJH A;  4OQ5 A;  2LR1 A;  4S0P A;  5FMI A;  4U2V A;  1R2E A;  5FDO A;  3D7V A;  3IHC A;  3KJ1 A;  2K7W A;  3CVA X;  4K5B C;  2PQK A;  4ZBI A;  4ZIG A;  2O2M A;  4YJ4 A;  1YSN A;  2V6Q A;  2VOI A;  2JCN A;  4ZII A;  3MK8 A;  5IEZ A;  4M0S A;  4QNQ A;  4BD8 A; 
#chains in the Genus database with same CATH homology
 2VVY A;  4BBB A;  2UXE A;  4UF1 A;  2VTY A;  4BBD A;  2JBX A;  4D2L A;  2JBY A;  2K36 A;  2I39 A;  2O42 A;  2VVX A;  2VVW A;  4BBC A;  3JRV A;  4D2M A;  4UF3 A;  4M0S A;  4LQK A;  4UF2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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