2JCNA

The crystal structure of bak1 - a mitochondrial apoptosis regulator
Total Genus 62
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
62
sequence length
162
structure length
157
Chain Sequence
SEEQVAQDTEEVFRSYVFYRHQQEQEAPADPEMVTLPLQPSSTMGQVGRQLAIIGDDINRRYDSEFQTMLQHLQPTAENAYEYFTKIATSLFESGINWGRVVALLGFGYRLALHVYQHGLTGFLGQVTRFVVDFMLHHCIARWIAQRGGWVAALNLG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Crystal Structure of Bak1 - an Apoptosis Trigger in the Mitochondrial Outer Membrane
rcsb
molecule tags Apoptosis
source organism Homo sapiens
molecule keywords BCL-2 HOMOLOGOUS ANTAGONIST/KILLER
total genus 62
structure length 157
sequence length 162
ec nomenclature
pdb deposition date 2006-12-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00452 Bcl-2 Apoptosis regulator proteins, Bcl-2 family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.437.10 Mainly Alpha Orthogonal Bundle Apoptosis Regulator Bcl-x Blc2-like 2jcnA00
1TY4A 2O2FA 5FDOA 3MK8A 1G5MA 4K5BC 1Q59A 5IF4A 2B48A 2BIDA 1BXLA 3MQPA 3IO9A 2JCNA 5FMIA 5KU9A 2IMSA 2M5BA 1MAZA 5KTGA 2IMTA 5FDRA 2BZWA 4ZIHA 5C3FA 2KUAA 4WMRA 2JM6B 4QVXA 4QNQA 1ZY3A 3I1HA 2O21A 2PQKA 4HW4A 2VOFA 1YSWA 3D7VA 2O22A 1R2IA 2ME8A 3IHDA 3IIGA 4YJ4A 1R2HA 2LR1A 3DVUA 4U2VA 4ZBFA 3WIYA 3WIXA 4ZEQA 3BL2A 2XPXA 3KZ0A 4OQ5A 4BD2A 1OHUA 4ZIIA 1LXLA 4HW2A 1WSXA 3IHEA 1YSGA 1R2GA 2O2MA 2A5YA 5FC4A 5C6HA 2MEJA 2W3LA 1DDBA 3PK1A 4S0PA 1R2DA 3IIHA 4HW3A 4BD6A 4G35A 2O2NA 2ABOA 2RODA 1AF3A 5JSBA 5IEZA 1YSNA 2KBWA 3KJ1A 4OYDA 2NL9A 4ZIGA 3CVAX 4OQ6A 4S0OA 4ZBIA 3ILCA 4BD8A 1R2EA 1GJHA 4BPJA 3KJ0A 4YK9A 1G5JA 4B4SA 2K7WA 2ROCA 3IHCA 2VOIA 4MI8A 1O0LA 2V6QA 1MK3A 4BD7A 3QBRA 2XA0A 2VOGA 2MHSA 1F16A 4BPIA 3KJ2A 2VM6A 4BDUA 1YSIA 1PQ1A 4U2UA 4ZIFA 1PQ0A 2NLAA 2VOHA 1K3KA 4ZIEA 2WH6A 2YV6A
chains in the Genus database with same CATH superfamily
1TY4A 2O2FA 2JBXA 5FDOA 3MK8A 1G5MA 4K5BC 1Q59A 5IF4A 2B48A 2BIDA 1BXLA 3MQPA 3IO9A 2JCNA 4UF2A 5FMIA 5KU9A 2IMSA 2M5BA 1MAZA 5KTGA 2IMTA 5FDRA 2BZWA 4ZIHA 4BBBA 5C3FA 2KUAA 4WMRA 2JM6B 2UXEA 4QVXA 4QNQA 1ZY3A 3I1HA 2VVYA 2VVWA 4BBDA 2O21A 2PQKA 4HW4A 2VOFA 2I39A 1YSWA 2VTYA 2O22A 1R2IA 3D7VA 2ME8A 3IHDA 3IIGA 2K36A 4YJ4A 1R2HA 2LR1A 4UF1A 4D2MA 3DVUA 4U2VA 4ZBFA 3WIYA 3WIXA 4ZEQA 3BL2A 2XPXA 3KZ0A 4OQ5A 4BD2A 1OHUA 4ZIIA 1LXLA 4HW2A 1WSXA 3IHEA 1YSGA 1R2GA 2O2MA 2A5YA 5FC4A 5C6HA 2MEJA 2W3LA 1DDBA 3PK1A 4S0PA 1R2DA 3IIHA 4HW3A 4M0SA 4BD6A 4G35A 2O2NA 2ABOA 2RODA 1AF3A 5JSBA 4UF3A 1YSNA 5IEZA 2KBWA 3KJ1A 2JBYA 4OYDA 2NL9A 4ZIGA 2O42A 3CVAX 3JRVA 4OQ6A 4S0OA 4ZBIA 3ILCA 4BD8A 4LQKA 1R2EA 1GJHA 4BPJA 3KJ0A 4YK9A 1G5JA 4B4SA 2K7WA 2ROCA 3IHCA 2VOIA 4MI8A 1O0LA 2V6QA 4D2LA 1MK3A 4BD7A 3QBRA 2XA0A 2VOGA 2MHSA 2VVXA 1F16A 4BPIA 3KJ2A 2VM6A 4BDUA 1YSIA 1PQ1A 4U2UA 4ZIFA 1PQ0A 2NLAA 4BBCA 2VOHA 1K3KA 4ZIEA 2WH6A 2YV6A
chains in the Genus database with same CATH topology
1TY4A 2O2FA 5FDOA 3MK8A 1G5MA 4K5BC 1Q59A 5IF4A 2B48A 2BIDA 1BXLA 3MQPA 3IO9A 2JCNA 5FMIA 5KU9A 2IMSA 2M5BA 1MAZA 5KTGA 2IMTA 5FDRA 2BZWA 4ZIHA 5C3FA 2KUAA 4WMRA 2JM6B 4QVXA 4QNQA 1ZY3A 3I1HA 2O21A 2PQKA 4HW4A 2VOFA 1YSWA 3D7VA 2O22A 1R2IA 2ME8A 3IHDA 3IIGA 4YJ4A 1R2HA 2LR1A 3DVUA 4U2VA 4ZBFA 3WIYA 3WIXA 4ZEQA 3BL2A 2XPXA 3KZ0A 4OQ5A 4BD2A 1OHUA 4ZIIA 1LXLA 4HW2A 1WSXA 3IHEA 1YSGA 1R2GA 2O2MA 2A5YA 5FC4A 5C6HA 2MEJA 2W3LA 1DDBA 3PK1A 4S0PA 1R2DA 3IIHA 4HW3A 4BD6A 4G35A 2O2NA 2ABOA 2RODA 1AF3A 5JSBA 5IEZA 1YSNA 2KBWA 3KJ1A 4OYDA 2NL9A 4ZIGA 3CVAX 4OQ6A 4S0OA 4ZBIA 3ILCA 4BD8A 1R2EA 1GJHA 4BPJA 3KJ0A 4YK9A 1G5JA 4B4SA 2K7WA 2ROCA 3IHCA 2VOIA 4MI8A 1O0LA 2V6QA 1MK3A 4BD7A 3QBRA 2XA0A 2VOGA 2MHSA 1F16A 4BPIA 3KJ2A 2VM6A 4BDUA 1YSIA 1PQ1A 4U2UA 4ZIFA 1PQ0A 2NLAA 2VOHA 1K3KA 4ZIEA 2WH6A 2YV6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TY4 A;  2O2F A;  5FDO A;  3MK8 A;  1G5M A;  4K5B C;  1Q59 A;  5IF4 A;  2B48 A;  2BID A;  1BXL A;  3MQP A;  3IO9 A;  2JCN A;  5FMI A;  5KU9 A;  2IMS A;  2M5B A;  1MAZ A;  5KTG A;  2IMT A;  5FDR A;  2BZW A;  4ZIH A;  5C3F A;  2KUA A;  4WMR A;  2JM6 B;  4QVX A;  4QNQ A;  1ZY3 A;  3I1H A;  2O21 A;  2PQK A;  4HW4 A;  2VOF A;  1YSW A;  3D7V A;  2O22 A;  1R2I A;  2ME8 A;  3IHD A;  3IIG A;  4YJ4 A;  1R2H A;  2LR1 A;  3DVU A;  4U2V A;  4ZBF A;  3WIY A;  3WIX A;  4ZEQ A;  3BL2 A;  2XPX A;  3KZ0 A;  4OQ5 A;  4BD2 A;  1OHU A;  4ZII A;  1LXL A;  4HW2 A;  1WSX A;  3IHE A;  1YSG A;  1R2G A;  2O2M A;  2A5Y A;  5FC4 A;  5C6H A;  2MEJ A;  2W3L A;  1DDB A;  3PK1 A;  4S0P A;  1R2D A;  3IIH A;  4HW3 A;  4BD6 A;  4G35 A;  2O2N A;  2ABO A;  2ROD A;  1AF3 A;  5JSB A;  5IEZ A;  1YSN A;  2KBW A;  3KJ1 A;  4OYD A;  2NL9 A;  4ZIG A;  3CVA X;  4OQ6 A;  4S0O A;  4ZBI A;  3ILC A;  4BD8 A;  1R2E A;  1GJH A;  4BPJ A;  3KJ0 A;  4YK9 A;  1G5J A;  4B4S A;  2K7W A;  2ROC A;  3IHC A;  2VOI A;  4MI8 A;  1O0L A;  2V6Q A;  1MK3 A;  4BD7 A;  3QBR A;  2XA0 A;  2VOG A;  2MHS A;  1F16 A;  4BPI A;  3KJ2 A;  2VM6 A;  4BDU A;  1YSI A;  1PQ1 A;  4U2U A;  4ZIF A;  1PQ0 A;  2NLA A;  2VOH A;  1K3K A;  4ZIE A;  2WH6 A;  2YV6 A; 
#chains in the Genus database with same CATH topology
 1TY4 A;  2O2F A;  2JBX A;  5FDO A;  3MK8 A;  1G5M A;  4K5B C;  1Q59 A;  5IF4 A;  2B48 A;  2BID A;  1BXL A;  3MQP A;  3IO9 A;  2JCN A;  4UF2 A;  5FMI A;  5KU9 A;  2IMS A;  2M5B A;  1MAZ A;  5KTG A;  2IMT A;  5FDR A;  2BZW A;  4ZIH A;  4BBB A;  5C3F A;  2KUA A;  4WMR A;  2JM6 B;  2UXE A;  4QVX A;  4QNQ A;  1ZY3 A;  3I1H A;  2VVY A;  2VVW A;  4BBD A;  2O21 A;  2PQK A;  4HW4 A;  2VOF A;  2I39 A;  1YSW A;  2VTY A;  2O22 A;  1R2I A;  3D7V A;  2ME8 A;  3IHD A;  3IIG A;  2K36 A;  4YJ4 A;  1R2H A;  2LR1 A;  4UF1 A;  4D2M A;  3DVU A;  4U2V A;  4ZBF A;  3WIY A;  3WIX A;  4ZEQ A;  3BL2 A;  2XPX A;  3KZ0 A;  4OQ5 A;  4BD2 A;  1OHU A;  4ZII A;  1LXL A;  4HW2 A;  1WSX A;  3IHE A;  1YSG A;  1R2G A;  2O2M A;  2A5Y A;  5FC4 A;  5C6H A;  2MEJ A;  2W3L A;  1DDB A;  3PK1 A;  4S0P A;  1R2D A;  3IIH A;  4HW3 A;  4M0S A;  4BD6 A;  4G35 A;  2O2N A;  2ABO A;  2ROD A;  1AF3 A;  5JSB A;  4UF3 A;  1YSN A;  5IEZ A;  2KBW A;  3KJ1 A;  2JBY A;  4OYD A;  2NL9 A;  4ZIG A;  2O42 A;  3CVA X;  3JRV A;  4OQ6 A;  4S0O A;  4ZBI A;  3ILC A;  4BD8 A;  4LQK A;  1R2E A;  1GJH A;  4BPJ A;  3KJ0 A;  4YK9 A;  1G5J A;  4B4S A;  2K7W A;  2ROC A;  3IHC A;  2VOI A;  4MI8 A;  1O0L A;  2V6Q A;  4D2L A;  1MK3 A;  4BD7 A;  3QBR A;  2XA0 A;  2VOG A;  2MHS A;  2VVX A;  1F16 A;  4BPI A;  3KJ2 A;  2VM6 A;  4BDU A;  1YSI A;  1PQ1 A;  4U2U A;  4ZIF A;  1PQ0 A;  2NLA A;  4BBC A;  2VOH A;  1K3K A;  4ZIE A;  2WH6 A;  2YV6 A; 
#chains in the Genus database with same CATH homology
 1TY4 A;  2O2F A;  5FDO A;  3MK8 A;  1G5M A;  4K5B C;  1Q59 A;  5IF4 A;  2B48 A;  2BID A;  1BXL A;  3MQP A;  3IO9 A;  2JCN A;  5FMI A;  5KU9 A;  2IMS A;  2M5B A;  1MAZ A;  5KTG A;  2IMT A;  5FDR A;  2BZW A;  4ZIH A;  5C3F A;  2KUA A;  4WMR A;  2JM6 B;  4QVX A;  4QNQ A;  1ZY3 A;  3I1H A;  2O21 A;  2PQK A;  4HW4 A;  2VOF A;  1YSW A;  3D7V A;  2O22 A;  1R2I A;  2ME8 A;  3IHD A;  3IIG A;  4YJ4 A;  1R2H A;  2LR1 A;  3DVU A;  4U2V A;  4ZBF A;  3WIY A;  3WIX A;  4ZEQ A;  3BL2 A;  2XPX A;  3KZ0 A;  4OQ5 A;  4BD2 A;  1OHU A;  4ZII A;  1LXL A;  4HW2 A;  1WSX A;  3IHE A;  1YSG A;  1R2G A;  2O2M A;  2A5Y A;  5FC4 A;  5C6H A;  2MEJ A;  2W3L A;  1DDB A;  3PK1 A;  4S0P A;  1R2D A;  3IIH A;  4HW3 A;  4BD6 A;  4G35 A;  2O2N A;  2ABO A;  2ROD A;  1AF3 A;  5JSB A;  5IEZ A;  1YSN A;  2KBW A;  3KJ1 A;  4OYD A;  2NL9 A;  4ZIG A;  3CVA X;  4OQ6 A;  4S0O A;  4ZBI A;  3ILC A;  4BD8 A;  1R2E A;  1GJH A;  4BPJ A;  3KJ0 A;  4YK9 A;  1G5J A;  4B4S A;  2K7W A;  2ROC A;  3IHC A;  2VOI A;  4MI8 A;  1O0L A;  2V6Q A;  1MK3 A;  4BD7 A;  3QBR A;  2XA0 A;  2VOG A;  2MHS A;  1F16 A;  4BPI A;  3KJ2 A;  2VM6 A;  4BDU A;  1YSI A;  1PQ1 A;  4U2U A;  4ZIF A;  1PQ0 A;  2NLA A;  2VOH A;  1K3K A;  4ZIE A;  2WH6 A;  2YV6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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