2KGXA

Haddock structure of the talin f3 domain in complex with talin 1655-1822
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
174
structure length
174
Chain Sequence
GIDPFTAPGQLECETAIAALNSCLRDLDQASLAAVSQQLAPREGISQEALHTQMLTAVQEISHLIEPLASAARAEASQLGHKVSQMAQYFEPLTLAAVGAASKTLSHPQQMALLDQTKTLAESALQLLYTAKEAGGNPKQAAHTQEALEEAVQMMTEAVEDLTTTLNEAASAAG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The structure of an interdomain complex that regulates talin activity.
pubmed doi rcsb
molecule keywords Talin-1
molecule tags Cell adhesion
source organism Mus musculus
total genus 63
structure length 174
sequence length 174
ec nomenclature
pdb deposition date 2009-03-23
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1420.10 Mainly Alpha Up-down Bundle A middle domain of Talin 1 Talin, central domain 2kgxA00
5FZTA 1SJ8A 3FYQA 2L7NA 4W8PA 1SJ7A 2L10A 2X0CA 2KVPA 2KGXA 4F7GB 3DYJA 2KBBA 3AY5A
chains in the Genus database with same CATH superfamily
5FZTA 3AT7A 5JDNA 3VJZA 5JDHA 2LQUA 5HYAA 3FYQA 2KBBA 3AY5A 3WSCA 3WURA 3M1CA 1SJ8A 5HWYA 5JDQA 4W8PA 4ECGA 5JDGA 2X0CA 2KVPA 2KGXA 5HXCA 5HWXA 5JDFA 5JDMA 3PHF1 3V5SA 3PF0A 4BGOA 2L10A 3DYJA 5HXRA 5HXEA 4ONRA 5JDLA 3V5UA 2L7NA 5T1DA 5HXHA 2XQYA 1SJ7A 5HXSA 2MTCA 4F7GB
chains in the Genus database with same CATH topology
5FZTA 1SJ8A 3FYQA 2L7NA 4W8PA 1SJ7A 2L10A 2X0CA 2KVPA 2KGXA 4F7GB 3DYJA 2KBBA 3AY5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5FZT A;  1SJ8 A;  3FYQ A;  2L7N A;  4W8P A;  1SJ7 A;  2L10 A;  2X0C A;  2KVP A;  2KGX A;  4F7G B;  3DYJ A;  2KBB A;  3AY5 A; 
#chains in the Genus database with same CATH topology
 5FZT A;  3AT7 A;  5JDN A;  3VJZ A;  5JDH A;  2LQU A;  5HYA A;  3FYQ A;  2KBB A;  3AY5 A;  3WSC A;  3WUR A;  3M1C A;  1SJ8 A;  5HWY A;  5JDQ A;  4W8P A;  4ECG A;  5JDG A;  2X0C A;  2KVP A;  2KGX A;  5HXC A;  5HWX A;  5JDF A;  5JDM A;  3PHF 1;  3V5S A;  3PF0 A;  4BGO A;  2L10 A;  3DYJ A;  5HXR A;  5HXE A;  4ONR A;  5JDL A;  3V5U A;  2L7N A;  5T1D A;  5HXH A;  2XQY A;  1SJ7 A;  5HXS A;  2MTC A;  4F7G B; 
#chains in the Genus database with same CATH homology
 5FZT A;  1SJ8 A;  3FYQ A;  2L7N A;  4W8P A;  1SJ7 A;  2L10 A;  2X0C A;  2KVP A;  2KGX A;  4F7G B;  3DYJ A;  2KBB A;  3AY5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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