2KVEA

C-terminal domain of mesencephalic astrocyte-derived neurotrophic factor (manf)
Total Genus 11
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
65
structure length
65
Chain Sequence
MGKYDKQIDLSTVDLKKLRVKELKKILDDWGETCKGCAEKSDYIRKINELMPKYAPKAASARTDL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Mesencephalic Astrocyte-derived Neurotrophic Factor (MANF) Has a Unique Mechanism to Rescue Apoptotic Neurons
pubmed doi rcsb
molecule tags Hormone
source organism Homo sapiens
molecule keywords Mesencephalic astrocyte-derived neurotrophic factor
total genus 11
structure length 65
sequence length 65
ec nomenclature
pdb deposition date 2010-03-12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.720.30 Mainly Alpha Orthogonal Bundle Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 SAP domain 2kveA00
2KVDA 2RNNA 2RNOA 1JJRA 2KVUA 4UZWA 1JEQA 2JVWA 1V66A 2KW9A 1H1JS 4BITA 1ZBHA 2WQGA 2KVEA
chains in the Genus database with same CATH superfamily
1ZS9A 3L0OA 1A63A 2DK4A 2HJQA 1H9EA 1JEQA 1GJJA 2JVWA 2KFVA 2MPHA 2KVEA 2A8VA 1E7LA 3QKJA 1JEIA 1GKUB 1H9FA 1EN7A 2LC3A 1YNSA 2QNCA 1A62A 3LLRA 4UZWA 1H1JS 2KW9A 2QNFA 5CIUA 2ODCI 1E7DA 2LD7A 1A8VA 3FLGA 2KVUA 1V66A 4BITA 1Y02A 2ODGC 2RNNA 2G80A 2RNOA 1JJRA 1GL9B 1KHCA 1ZBHA 2WQGA 2KVDA 2W51A
chains in the Genus database with same CATH topology
2KVDA 2RNNA 2RNOA 1JJRA 2KVUA 4UZWA 1JEQA 2JVWA 1V66A 2KW9A 1H1JS 4BITA 1ZBHA 2WQGA 2KVEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KVD A;  2RNN A;  2RNO A;  1JJR A;  2KVU A;  4UZW A;  1JEQ A;  2JVW A;  1V66 A;  2KW9 A;  1H1J S;  4BIT A;  1ZBH A;  2WQG A;  2KVE A; 
#chains in the Genus database with same CATH topology
 1ZS9 A;  3L0O A;  1A63 A;  2DK4 A;  2HJQ A;  1H9E A;  1JEQ A;  1GJJ A;  2JVW A;  2KFV A;  2MPH A;  2KVE A;  2A8V A;  1E7L A;  3QKJ A;  1JEI A;  1GKU B;  1H9F A;  1EN7 A;  2LC3 A;  1YNS A;  2QNC A;  1A62 A;  3LLR A;  4UZW A;  1H1J S;  2KW9 A;  2QNF A;  5CIU A;  2ODC I;  1E7D A;  2LD7 A;  1A8V A;  3FLG A;  2KVU A;  1V66 A;  4BIT A;  1Y02 A;  2ODG C;  2RNN A;  2G80 A;  2RNO A;  1JJR A;  1GL9 B;  1KHC A;  1ZBH A;  2WQG A;  2KVD A;  2W51 A; 
#chains in the Genus database with same CATH homology
 2KVD A;  2RNN A;  2RNO A;  1JJR A;  2KVU A;  4UZW A;  1JEQ A;  2JVW A;  1V66 A;  2KW9 A;  1H1J S;  4BIT A;  1ZBH A;  2WQG A;  2KVE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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