2KVEA

C-terminal domain of mesencephalic astrocyte-derived neurotrophic factor (manf)
Total Genus 11
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
65
structure length
65
Chain Sequence
MGKYDKQIDLSTVDLKKLRVKELKKILDDWGETCKGCAEKSDYIRKINELMPKYAPKAASARTDL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Mesencephalic Astrocyte-derived Neurotrophic Factor (MANF) Has a Unique Mechanism to Rescue Apoptotic Neurons
pubmed doi rcsb
molecule keywords Mesencephalic astrocyte-derived neurotrophic factor
molecule tags Hormone
source organism Homo sapiens
total genus 11
structure length 65
sequence length 65
ec nomenclature
pdb deposition date 2010-03-12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.720.30 Mainly Alpha Orthogonal Bundle Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 SAP domain 2kveA00
2RNOA 1JJRA 2KVUA 4BITA 1JEQA 2KVDA 2RNNA 2WQGA 1H1JS 4UZWA 2KVEA 1V66A 2JVWA 1ZBHA 2KW9A
chains in the Genus database with same CATH superfamily
2LD7A 2KVDA 2RNNA 2ODCI 3QKJA 1EN7A 1GJJA 2JVWA 1GKUB 1A63A 3FLGA 3L0OA 1V66A 1KHCA 2QNCA 2KW9A 1E7LA 2MPHA 2RNOA 2W51A 1Y02A 4BITA 2HJQA 2ODGC 3LLRA 4UZWA 2G80A 1ZBHA 1H9EA 5CIUA 1JJRA 2KVUA 1YNSA 1JEQA 1H1JS 2WQGA 1H9FA 1E7DA 2A8VA 2KVEA 2LC3A 1A62A 2DK4A 1ZS9A 2QNFA 1GL9B 1JEIA 2KFVA 1A8VA
chains in the Genus database with same CATH topology
2RNOA 1JJRA 2KVUA 4BITA 1JEQA 2KVDA 2RNNA 2WQGA 1H1JS 4UZWA 2KVEA 1V66A 2JVWA 1ZBHA 2KW9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2RNO A;  1JJR A;  2KVU A;  4BIT A;  1JEQ A;  2KVD A;  2RNN A;  2WQG A;  1H1J S;  4UZW A;  2KVE A;  1V66 A;  2JVW A;  1ZBH A;  2KW9 A; 
#chains in the Genus database with same CATH topology
 2LD7 A;  2KVD A;  2RNN A;  2ODC I;  3QKJ A;  1EN7 A;  1GJJ A;  2JVW A;  1GKU B;  1A63 A;  3FLG A;  3L0O A;  1V66 A;  1KHC A;  2QNC A;  2KW9 A;  1E7L A;  2MPH A;  2RNO A;  2W51 A;  1Y02 A;  4BIT A;  2HJQ A;  2ODG C;  3LLR A;  4UZW A;  2G80 A;  1ZBH A;  1H9E A;  5CIU A;  1JJR A;  2KVU A;  1YNS A;  1JEQ A;  1H1J S;  2WQG A;  1H9F A;  1E7D A;  2A8V A;  2KVE A;  2LC3 A;  1A62 A;  2DK4 A;  1ZS9 A;  2QNF A;  1GL9 B;  1JEI A;  2KFV A;  1A8V A; 
#chains in the Genus database with same CATH homology
 2RNO A;  1JJR A;  2KVU A;  4BIT A;  1JEQ A;  2KVD A;  2RNN A;  2WQG A;  1H1J S;  4UZW A;  2KVE A;  1V66 A;  2JVW A;  1ZBH A;  2KW9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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