2KVEA

C-terminal domain of mesencephalic astrocyte-derived neurotrophic factor (manf)
Total Genus 11
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
65
structure length
65
Chain Sequence
MGKYDKQIDLSTVDLKKLRVKELKKILDDWGETCKGCAEKSDYIRKINELMPKYAPKAASARTDL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Mesencephalic Astrocyte-derived Neurotrophic Factor (MANF) Has a Unique Mechanism to Rescue Apoptotic Neurons
pubmed doi rcsb
molecule keywords Mesencephalic astrocyte-derived neurotrophic factor
molecule tags Hormone
source organism Homo sapiens
total genus 11
structure length 65
sequence length 65
ec nomenclature
pdb deposition date 2010-03-12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.720.30 Mainly Alpha Orthogonal Bundle Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 SAP domain 2kveA00
1ZBHA 2KVUA 1JJRA 4UZWA 2KW9A 2KVEA 2KVDA 2RNOA 1V66A 1H1JS 2RNNA 1JEQA 2WQGA 4BITA 2JVWA
chains in the Genus database with same CATH superfamily
1ZBHA 1A63A 3L0OA 2QNCA 1JEIA 1H1JS 1E7DA 1E7LA 2HJQA 1A8VA 2LD7A 2JVWA 1JJRA 1Y02A 1GJJA 2KVDA 1GL9B 1V66A 2RNOA 2A8VA 1JEQA 4BITA 1YNSA 2ODGC 1GKUB 2QNFA 2KVUA 1KHCA 1EN7A 2G80A 3QKJA 2KW9A 4UZWA 1H9FA 3FLGA 2RNNA 2WQGA 2MPHA 2DK4A 2LC3A 1H9EA 2KVEA 2W51A 2KFVA 2ODCI 3LLRA 5CIUA 1ZS9A 1A62A
chains in the Genus database with same CATH topology
1ZBHA 2KVUA 1JJRA 4UZWA 2KW9A 2KVEA 2KVDA 2RNOA 1V66A 1H1JS 2RNNA 1JEQA 2WQGA 4BITA 2JVWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ZBH A;  2KVU A;  1JJR A;  4UZW A;  2KW9 A;  2KVE A;  2KVD A;  2RNO A;  1V66 A;  1H1J S;  2RNN A;  1JEQ A;  2WQG A;  4BIT A;  2JVW A; 
#chains in the Genus database with same CATH topology
 1ZBH A;  1A63 A;  3L0O A;  2QNC A;  1JEI A;  1H1J S;  1E7D A;  1E7L A;  2HJQ A;  1A8V A;  2LD7 A;  2JVW A;  1JJR A;  1Y02 A;  1GJJ A;  2KVD A;  1GL9 B;  1V66 A;  2RNO A;  2A8V A;  1JEQ A;  4BIT A;  1YNS A;  2ODG C;  1GKU B;  2QNF A;  2KVU A;  1KHC A;  1EN7 A;  2G80 A;  3QKJ A;  2KW9 A;  4UZW A;  1H9F A;  3FLG A;  2RNN A;  2WQG A;  2MPH A;  2DK4 A;  2LC3 A;  1H9E A;  2KVE A;  2W51 A;  2KFV A;  2ODC I;  3LLR A;  5CIU A;  1ZS9 A;  1A62 A; 
#chains in the Genus database with same CATH homology
 1ZBH A;  2KVU A;  1JJR A;  4UZW A;  2KW9 A;  2KVE A;  2KVD A;  2RNO A;  1V66 A;  1H1J S;  2RNN A;  1JEQ A;  2WQG A;  4BIT A;  2JVW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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