2KVEA

C-terminal domain of mesencephalic astrocyte-derived neurotrophic factor (manf)
Total Genus 11
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
65
structure length
65
Chain Sequence
MGKYDKQIDLSTVDLKKLRVKELKKILDDWGETCKGCAEKSDYIRKINELMPKYAPKAASARTDL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Mesencephalic Astrocyte-derived Neurotrophic Factor (MANF) Has a Unique Mechanism to Rescue Apoptotic Neurons
pubmed doi rcsb
molecule keywords Mesencephalic astrocyte-derived neurotrophic factor
molecule tags Hormone
source organism Homo sapiens
total genus 11
structure length 65
sequence length 65
ec nomenclature
pdb deposition date 2010-03-12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.720.30 Mainly Alpha Orthogonal Bundle Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 SAP domain 2kveA00
4BITA 2KVDA 2RNNA 1JEQA 2KVUA 4UZWA 1V66A 2WQGA 1JJRA 2KW9A 1ZBHA 2JVWA 2RNOA 2KVEA 1H1JS
chains in the Genus database with same CATH superfamily
2ODCI 1JEIA 1GJJA 3LLRA 2A8VA 2QNFA 1V66A 3QKJA 1E7DA 2LC3A 2KVEA 2QNCA 5CIUA 1A63A 2MPHA 1GKUB 1KHCA 1EN7A 2KVUA 1H9FA 2WQGA 2KW9A 1ZS9A 2KFVA 1E7LA 1A8VA 2KVDA 1Y02A 2RNOA 3FLGA 1A62A 1JEQA 2W51A 3L0OA 2JVWA 2ODGC 2LD7A 1H9EA 2HJQA 4BITA 2RNNA 2DK4A 4UZWA 1JJRA 1ZBHA 1YNSA 2G80A 1GL9B 1H1JS
chains in the Genus database with same CATH topology
4BITA 2KVDA 2RNNA 1JEQA 2KVUA 4UZWA 1V66A 2WQGA 1JJRA 2KW9A 1ZBHA 2JVWA 2RNOA 2KVEA 1H1JS
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BIT A;  2KVD A;  2RNN A;  1JEQ A;  2KVU A;  4UZW A;  1V66 A;  2WQG A;  1JJR A;  2KW9 A;  1ZBH A;  2JVW A;  2RNO A;  2KVE A;  1H1J S; 
#chains in the Genus database with same CATH topology
 2ODC I;  1JEI A;  1GJJ A;  3LLR A;  2A8V A;  2QNF A;  1V66 A;  3QKJ A;  1E7D A;  2LC3 A;  2KVE A;  2QNC A;  5CIU A;  1A63 A;  2MPH A;  1GKU B;  1KHC A;  1EN7 A;  2KVU A;  1H9F A;  2WQG A;  2KW9 A;  1ZS9 A;  2KFV A;  1E7L A;  1A8V A;  2KVD A;  1Y02 A;  2RNO A;  3FLG A;  1A62 A;  1JEQ A;  2W51 A;  3L0O A;  2JVW A;  2ODG C;  2LD7 A;  1H9E A;  2HJQ A;  4BIT A;  2RNN A;  2DK4 A;  4UZW A;  1JJR A;  1ZBH A;  1YNS A;  2G80 A;  1GL9 B;  1H1J S; 
#chains in the Genus database with same CATH homology
 4BIT A;  2KVD A;  2RNN A;  1JEQ A;  2KVU A;  4UZW A;  1V66 A;  2WQG A;  1JJR A;  2KW9 A;  1ZBH A;  2JVW A;  2RNO A;  2KVE A;  1H1J S; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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