2KVEA

C-terminal domain of mesencephalic astrocyte-derived neurotrophic factor (manf)
Total Genus 11
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
65
structure length
65
Chain Sequence
MGKYDKQIDLSTVDLKKLRVKELKKILDDWGETCKGCAEKSDYIRKINELMPKYAPKAASARTDL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Mesencephalic Astrocyte-derived Neurotrophic Factor (MANF) Has a Unique Mechanism to Rescue Apoptotic Neurons
pubmed doi rcsb
molecule tags Hormone
source organism Homo sapiens
molecule keywords Mesencephalic astrocyte-derived neurotrophic factor
total genus 11
structure length 65
sequence length 65
ec nomenclature
pdb deposition date 2010-03-12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.720.30 Mainly Alpha Orthogonal Bundle Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 SAP domain 2kveA00
2WQGA 1V66A 2KVEA 2RNOA 2KVDA 4BITA 2KVUA 1JJRA 4UZWA 1ZBHA 1H1JS 2KW9A 1JEQA 2JVWA 2RNNA
chains in the Genus database with same CATH superfamily
1YNSA 1ZS9A 1GKUB 2WQGA 2LD7A 1H9FA 3QKJA 2A8VA 1JEIA 1E7LA 1A63A 2KFVA 1ZBHA 3L0OA 2G80A 2ODCI 1V66A 1A62A 2KVEA 1GJJA 1A8VA 2QNCA 1JJRA 1H1JS 1EN7A 2LC3A 1Y02A 2W51A 5CIUA 1E7DA 3LLRA 2DK4A 3FLGA 2KVUA 2JVWA 2RNNA 1KHCA 1GL9B 2ODGC 2RNOA 2MPHA 2HJQA 2KVDA 4BITA 1H9EA 4UZWA 2KW9A 1JEQA 2QNFA
chains in the Genus database with same CATH topology
2WQGA 1V66A 2KVEA 2RNOA 2KVDA 4BITA 2KVUA 1JJRA 4UZWA 1ZBHA 1H1JS 2KW9A 1JEQA 2JVWA 2RNNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2WQG A;  1V66 A;  2KVE A;  2RNO A;  2KVD A;  4BIT A;  2KVU A;  1JJR A;  4UZW A;  1ZBH A;  1H1J S;  2KW9 A;  1JEQ A;  2JVW A;  2RNN A; 
#chains in the Genus database with same CATH topology
 1YNS A;  1ZS9 A;  1GKU B;  2WQG A;  2LD7 A;  1H9F A;  3QKJ A;  2A8V A;  1JEI A;  1E7L A;  1A63 A;  2KFV A;  1ZBH A;  3L0O A;  2G80 A;  2ODC I;  1V66 A;  1A62 A;  2KVE A;  1GJJ A;  1A8V A;  2QNC A;  1JJR A;  1H1J S;  1EN7 A;  2LC3 A;  1Y02 A;  2W51 A;  5CIU A;  1E7D A;  3LLR A;  2DK4 A;  3FLG A;  2KVU A;  2JVW A;  2RNN A;  1KHC A;  1GL9 B;  2ODG C;  2RNO A;  2MPH A;  2HJQ A;  2KVD A;  4BIT A;  1H9E A;  4UZW A;  2KW9 A;  1JEQ A;  2QNF A; 
#chains in the Genus database with same CATH homology
 2WQG A;  1V66 A;  2KVE A;  2RNO A;  2KVD A;  4BIT A;  2KVU A;  1JJR A;  4UZW A;  1ZBH A;  1H1J S;  2KW9 A;  1JEQ A;  2JVW A;  2RNN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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