2KVPA

Nmr structure of the talin vbs3 domain, 1815-1973
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
165
structure length
165
Chain Sequence
GIDPFTNEAASAAGVVGGMVDSITQAINQLDEGPMGDPEGSFVDYQTTMVRTAKAIAVTVQEMVTKSNTSPEELGPLANQLTSDYGRLASQAKPAAVAAENEEIGAHIKHRVQELGHGCSALVTKAGALQCSPSDVYTKKELIECARRVSEKVSHVLAALQAGNR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Structural protein
source organism Mus musculus
publication title The domain structure of talin: Residues 1815-1973 form a five-helix bundle containing a cryptic vinculin-binding site.
pubmed doi rcsb
molecule keywords Talin-1
total genus 57
structure length 165
sequence length 165
ec nomenclature
pdb deposition date 2010-03-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08913 VBS Vinculin Binding Site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1420.10 Mainly Alpha Up-down Bundle A middle domain of Talin 1 Talin, central domain 2kvpA00
2KGXA 3AY5A 5FZTA 2KBBA 3FYQA 1SJ7A 3DYJA 4W8PA 2KVPA 4F7GB 2X0CA 2L7NA 2L10A 1SJ8A
chains in the Genus database with same CATH superfamily
5HWXA 5JDNA 5HWYA 5JDMA 3DYJA 2XQYA 2KVPA 5T1DA 5JDGA 4ONRA 2X0CA 2L7NA 4BGOA 4ECGA 4W8PA 2L10A 1SJ8A 3V5SA 2KBBA 5HXRA 1SJ7A 5JDQA 2MTCA 3VJZA 3WURA 5HXHA 5HYAA 3V5UA 5JDHA 3PF0A 5JDFA 3FYQA 5HXCA 3WSCA 2LQUA 2KGXA 3AY5A 5FZTA 5HXEA 3M1CA 3AT7A 4F7GB 5HXSA 3PHF1 5JDLA
chains in the Genus database with same CATH topology
2KGXA 3AY5A 5FZTA 2KBBA 3FYQA 1SJ7A 3DYJA 4W8PA 2KVPA 4F7GB 2X0CA 2L7NA 2L10A 1SJ8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KGX A;  3AY5 A;  5FZT A;  2KBB A;  3FYQ A;  1SJ7 A;  3DYJ A;  4W8P A;  2KVP A;  4F7G B;  2X0C A;  2L7N A;  2L10 A;  1SJ8 A; 
#chains in the Genus database with same CATH topology
 5HWX A;  5JDN A;  5HWY A;  5JDM A;  3DYJ A;  2XQY A;  2KVP A;  5T1D A;  5JDG A;  4ONR A;  2X0C A;  2L7N A;  4BGO A;  4ECG A;  4W8P A;  2L10 A;  1SJ8 A;  3V5S A;  2KBB A;  5HXR A;  1SJ7 A;  5JDQ A;  2MTC A;  3VJZ A;  3WUR A;  5HXH A;  5HYA A;  3V5U A;  5JDH A;  3PF0 A;  5JDF A;  3FYQ A;  5HXC A;  3WSC A;  2LQU A;  2KGX A;  3AY5 A;  5FZT A;  5HXE A;  3M1C A;  3AT7 A;  4F7G B;  5HXS A;  3PHF 1;  5JDL A; 
#chains in the Genus database with same CATH homology
 2KGX A;  3AY5 A;  5FZT A;  2KBB A;  3FYQ A;  1SJ7 A;  3DYJ A;  4W8P A;  2KVP A;  4F7G B;  2X0C A;  2L7N A;  2L10 A;  1SJ8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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