2KVPA

Nmr structure of the talin vbs3 domain, 1815-1973
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
165
structure length
165
Chain Sequence
GIDPFTNEAASAAGVVGGMVDSITQAINQLDEGPMGDPEGSFVDYQTTMVRTAKAIAVTVQEMVTKSNTSPEELGPLANQLTSDYGRLASQAKPAAVAAENEEIGAHIKHRVQELGHGCSALVTKAGALQCSPSDVYTKKELIECARRVSEKVSHVLAALQAGNR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The domain structure of talin: Residues 1815-1973 form a five-helix bundle containing a cryptic vinculin-binding site.
pubmed doi rcsb
molecule keywords Talin-1
molecule tags Structural protein
source organism Mus musculus
total genus 57
structure length 165
sequence length 165
ec nomenclature
pdb deposition date 2010-03-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08913 VBS Vinculin Binding Site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1420.10 Mainly Alpha Up-down Bundle A middle domain of Talin 1 Talin, central domain 2kvpA00
2KBBA 2KVPA 5FZTA 4F7GB 3DYJA 1SJ8A 2KGXA 1SJ7A 2L10A 3FYQA 4W8PA 3AY5A 2X0CA 2L7NA
chains in the Genus database with same CATH superfamily
2KVPA 2KGXA 3V5SA 2LQUA 3WSCA 3M1CA 5JDHA 5JDNA 5HXHA 2KBBA 5HXEA 2MTCA 5HXCA 5HYAA 3V5UA 5T1DA 2L7NA 5FZTA 4F7GB 2XQYA 1SJ7A 3FYQA 4W8PA 3VJZA 3WURA 5JDLA 4ECGA 5JDGA 5HWXA 5HXSA 3DYJA 1SJ8A 2L10A 5HXRA 5JDMA 4BGOA 3PHF1 3AT7A 3AY5A 4ONRA 2X0CA 3PF0A 5JDFA 5HWYA 5JDQA
chains in the Genus database with same CATH topology
2KBBA 2KVPA 5FZTA 4F7GB 3DYJA 1SJ8A 2KGXA 1SJ7A 2L10A 3FYQA 4W8PA 3AY5A 2X0CA 2L7NA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KBB A;  2KVP A;  5FZT A;  4F7G B;  3DYJ A;  1SJ8 A;  2KGX A;  1SJ7 A;  2L10 A;  3FYQ A;  4W8P A;  3AY5 A;  2X0C A;  2L7N A; 
#chains in the Genus database with same CATH topology
 2KVP A;  2KGX A;  3V5S A;  2LQU A;  3WSC A;  3M1C A;  5JDH A;  5JDN A;  5HXH A;  2KBB A;  5HXE A;  2MTC A;  5HXC A;  5HYA A;  3V5U A;  5T1D A;  2L7N A;  5FZT A;  4F7G B;  2XQY A;  1SJ7 A;  3FYQ A;  4W8P A;  3VJZ A;  3WUR A;  5JDL A;  4ECG A;  5JDG A;  5HWX A;  5HXS A;  3DYJ A;  1SJ8 A;  2L10 A;  5HXR A;  5JDM A;  4BGO A;  3PHF 1;  3AT7 A;  3AY5 A;  4ONR A;  2X0C A;  3PF0 A;  5JDF A;  5HWY A;  5JDQ A; 
#chains in the Genus database with same CATH homology
 2KBB A;  2KVP A;  5FZT A;  4F7G B;  3DYJ A;  1SJ8 A;  2KGX A;  1SJ7 A;  2L10 A;  3FYQ A;  4W8P A;  3AY5 A;  2X0C A;  2L7N A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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