2KVPA

Nmr structure of the talin vbs3 domain, 1815-1973
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
165
structure length
165
Chain Sequence
GIDPFTNEAASAAGVVGGMVDSITQAINQLDEGPMGDPEGSFVDYQTTMVRTAKAIAVTVQEMVTKSNTSPEELGPLANQLTSDYGRLASQAKPAAVAAENEEIGAHIKHRVQELGHGCSALVTKAGALQCSPSDVYTKKELIECARRVSEKVSHVLAALQAGNR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The domain structure of talin: Residues 1815-1973 form a five-helix bundle containing a cryptic vinculin-binding site.
pubmed doi rcsb
molecule tags Structural protein
source organism Mus musculus
molecule keywords Talin-1
total genus 57
structure length 165
sequence length 165
ec nomenclature
pdb deposition date 2010-03-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08913 VBS Vinculin Binding Site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1420.10 Mainly Alpha Up-down Bundle A middle domain of Talin 1 Talin, central domain 2kvpA00
2KGXA 2X0CA 1SJ8A 2KBBA 2L10A 4W8PA 4F7GB 2KVPA 1SJ7A 5FZTA 3AY5A 2L7NA 3FYQA 3DYJA
chains in the Genus database with same CATH superfamily
5JDHA 5HWYA 5HXEA 5JDLA 5JDMA 3VJZA 2XQYA 4W8PA 5HXHA 3WURA 5T1DA 4BGOA 5HWXA 5JDQA 4ONRA 2LQUA 5HXCA 5JDFA 2MTCA 1SJ7A 5JDNA 5FZTA 3AY5A 4F7GB 2KGXA 3V5SA 1SJ8A 2KBBA 3M1CA 3PHF1 3AT7A 4ECGA 2KVPA 3DYJA 2X0CA 3PF0A 2L10A 5HXRA 3WSCA 5HXSA 5JDGA 5HYAA 2L7NA 3FYQA 3V5UA
chains in the Genus database with same CATH topology
2KGXA 2X0CA 1SJ8A 2KBBA 2L10A 4W8PA 4F7GB 2KVPA 1SJ7A 5FZTA 3AY5A 2L7NA 3FYQA 3DYJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KGX A;  2X0C A;  1SJ8 A;  2KBB A;  2L10 A;  4W8P A;  4F7G B;  2KVP A;  1SJ7 A;  5FZT A;  3AY5 A;  2L7N A;  3FYQ A;  3DYJ A; 
#chains in the Genus database with same CATH topology
 5JDH A;  5HWY A;  5HXE A;  5JDL A;  5JDM A;  3VJZ A;  2XQY A;  4W8P A;  5HXH A;  3WUR A;  5T1D A;  4BGO A;  5HWX A;  5JDQ A;  4ONR A;  2LQU A;  5HXC A;  5JDF A;  2MTC A;  1SJ7 A;  5JDN A;  5FZT A;  3AY5 A;  4F7G B;  2KGX A;  3V5S A;  1SJ8 A;  2KBB A;  3M1C A;  3PHF 1;  3AT7 A;  4ECG A;  2KVP A;  3DYJ A;  2X0C A;  3PF0 A;  2L10 A;  5HXR A;  3WSC A;  5HXS A;  5JDG A;  5HYA A;  2L7N A;  3FYQ A;  3V5U A; 
#chains in the Genus database with same CATH homology
 2KGX A;  2X0C A;  1SJ8 A;  2KBB A;  2L10 A;  4W8P A;  4F7G B;  2KVP A;  1SJ7 A;  5FZT A;  3AY5 A;  2L7N A;  3FYQ A;  3DYJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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