2KVPA

Nmr structure of the talin vbs3 domain, 1815-1973
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
165
structure length
165
Chain Sequence
GIDPFTNEAASAAGVVGGMVDSITQAINQLDEGPMGDPEGSFVDYQTTMVRTAKAIAVTVQEMVTKSNTSPEELGPLANQLTSDYGRLASQAKPAAVAAENEEIGAHIKHRVQELGHGCSALVTKAGALQCSPSDVYTKKELIECARRVSEKVSHVLAALQAGNR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The domain structure of talin: Residues 1815-1973 form a five-helix bundle containing a cryptic vinculin-binding site.
pubmed doi rcsb
molecule tags Structural protein
source organism Mus musculus
molecule keywords Talin-1
total genus 57
structure length 165
sequence length 165
ec nomenclature
pdb deposition date 2010-03-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08913 VBS Vinculin Binding Site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1420.10 Mainly Alpha Up-down Bundle A middle domain of Talin 1 Talin, central domain 2kvpA00
2L7NA 2X0CA 2KBBA 3AY5A 4F7GB 4W8PA 1SJ7A 5FZTA 2KVPA 2KGXA 1SJ8A 3DYJA 3FYQA 2L10A
chains in the Genus database with same CATH superfamily
5JDQA 2X0CA 5HXHA 4F7GB 4ONRA 3WURA 3PHF1 2MTCA 5JDGA 1SJ8A 5T1DA 5JDHA 5HXRA 5HXCA 2L10A 2KBBA 3M1CA 3V5UA 3VJZA 3WSCA 5JDLA 2KVPA 5HYAA 2L7NA 5JDMA 5HWYA 3AY5A 2XQYA 4W8PA 1SJ7A 5JDFA 5HWXA 5HXEA 3FYQA 5FZTA 2LQUA 5JDNA 2KGXA 4BGOA 4ECGA 3PF0A 5HXSA 3AT7A 3V5SA 3DYJA
chains in the Genus database with same CATH topology
2L7NA 2X0CA 2KBBA 3AY5A 4F7GB 4W8PA 1SJ7A 5FZTA 2KVPA 2KGXA 1SJ8A 3DYJA 3FYQA 2L10A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2L7N A;  2X0C A;  2KBB A;  3AY5 A;  4F7G B;  4W8P A;  1SJ7 A;  5FZT A;  2KVP A;  2KGX A;  1SJ8 A;  3DYJ A;  3FYQ A;  2L10 A; 
#chains in the Genus database with same CATH topology
 5JDQ A;  2X0C A;  5HXH A;  4F7G B;  4ONR A;  3WUR A;  3PHF 1;  2MTC A;  5JDG A;  1SJ8 A;  5T1D A;  5JDH A;  5HXR A;  5HXC A;  2L10 A;  2KBB A;  3M1C A;  3V5U A;  3VJZ A;  3WSC A;  5JDL A;  2KVP A;  5HYA A;  2L7N A;  5JDM A;  5HWY A;  3AY5 A;  2XQY A;  4W8P A;  1SJ7 A;  5JDF A;  5HWX A;  5HXE A;  3FYQ A;  5FZT A;  2LQU A;  5JDN A;  2KGX A;  4BGO A;  4ECG A;  3PF0 A;  5HXS A;  3AT7 A;  3V5S A;  3DYJ A; 
#chains in the Genus database with same CATH homology
 2L7N A;  2X0C A;  2KBB A;  3AY5 A;  4F7G B;  4W8P A;  1SJ7 A;  5FZT A;  2KVP A;  2KGX A;  1SJ8 A;  3DYJ A;  3FYQ A;  2L10 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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