2L10A

Structure of the talin rod residues, domain c
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
158
structure length
158
Chain Sequence
GIDPFTQRDVDNALRAVGDASKRLLSDLLPPSTGTFQEAQSRLNEAAAGLNQAATELVQASRGTPQDLARASGRFGQDFSTFLEAGVEMAGQAPSQEDRAQVVSNLKGISMSSSKLLLAAKALSTDPASPNLKSQLAAAARAVTDSINQLITMCTQQA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title RIAM and vinculin binding to talin are mutually exclusive and regulate adhesion assembly and turnover.
pubmed doi rcsb
molecule tags Structural protein
source organism Mus musculus
molecule keywords Talin-1
total genus 60
structure length 158
sequence length 158
ec nomenclature
pdb deposition date 2010-07-22
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1420.10 Mainly Alpha Up-down Bundle A middle domain of Talin 1 Talin, central domain 2l10A00
2KVPA 2KGXA 3AY5A 2L7NA 3FYQA 4W8PA 5FZTA 4F7GB 2L10A 3DYJA 1SJ7A 2KBBA 1SJ8A 2X0CA
chains in the Genus database with same CATH superfamily
5JDQA 2KVPA 5JDFA 3AT7A 4ONRA 5HXCA 4ECGA 3DYJA 5HWYA 5HYAA 2X0CA 2LQUA 5HXEA 3VJZA 2L7NA 5FZTA 4F7GB 5JDHA 3V5UA 3M1CA 5T1DA 3PF0A 3PHF1 5JDMA 3FYQA 4W8PA 5HXRA 2L10A 2MTCA 3V5SA 5JDGA 2KBBA 5JDNA 1SJ8A 5HXSA 3AY5A 4BGOA 5HWXA 3WSCA 2XQYA 3WURA 1SJ7A 5HXHA 2KGXA 5JDLA
chains in the Genus database with same CATH topology
2KVPA 2KGXA 3AY5A 2L7NA 3FYQA 4W8PA 5FZTA 4F7GB 2L10A 3DYJA 1SJ7A 2KBBA 1SJ8A 2X0CA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KVP A;  2KGX A;  3AY5 A;  2L7N A;  3FYQ A;  4W8P A;  5FZT A;  4F7G B;  2L10 A;  3DYJ A;  1SJ7 A;  2KBB A;  1SJ8 A;  2X0C A; 
#chains in the Genus database with same CATH topology
 5JDQ A;  2KVP A;  5JDF A;  3AT7 A;  4ONR A;  5HXC A;  4ECG A;  3DYJ A;  5HWY A;  5HYA A;  2X0C A;  2LQU A;  5HXE A;  3VJZ A;  2L7N A;  5FZT A;  4F7G B;  5JDH A;  3V5U A;  3M1C A;  5T1D A;  3PF0 A;  3PHF 1;  5JDM A;  3FYQ A;  4W8P A;  5HXR A;  2L10 A;  2MTC A;  3V5S A;  5JDG A;  2KBB A;  5JDN A;  1SJ8 A;  5HXS A;  3AY5 A;  4BGO A;  5HWX A;  3WSC A;  2XQY A;  3WUR A;  1SJ7 A;  5HXH A;  2KGX A;  5JDL A; 
#chains in the Genus database with same CATH homology
 2KVP A;  2KGX A;  3AY5 A;  2L7N A;  3FYQ A;  4W8P A;  5FZT A;  4F7G B;  2L10 A;  3DYJ A;  1SJ7 A;  2KBB A;  1SJ8 A;  2X0C A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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