2L10A

Structure of the talin rod residues, domain c
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
158
structure length
158
Chain Sequence
GIDPFTQRDVDNALRAVGDASKRLLSDLLPPSTGTFQEAQSRLNEAAAGLNQAATELVQASRGTPQDLARASGRFGQDFSTFLEAGVEMAGQAPSQEDRAQVVSNLKGISMSSSKLLLAAKALSTDPASPNLKSQLAAAARAVTDSINQLITMCTQQA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title RIAM and vinculin binding to talin are mutually exclusive and regulate adhesion assembly and turnover.
pubmed doi rcsb
molecule tags Structural protein
source organism Mus musculus
molecule keywords Talin-1
total genus 60
structure length 158
sequence length 158
ec nomenclature
pdb deposition date 2010-07-22
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1420.10 Mainly Alpha Up-down Bundle A middle domain of Talin 1 Talin, central domain 2l10A00
1SJ7A 1SJ8A 5FZTA 4F7GB 4W8PA 2KVPA 2KGXA 3DYJA 2L10A 3AY5A 3FYQA 2X0CA 2L7NA 2KBBA
chains in the Genus database with same CATH superfamily
5HXCA 5HWYA 3VJZA 1SJ8A 4W8PA 3FYQA 5HWXA 3PF0A 2XQYA 5JDNA 3WSCA 2MTCA 5HXHA 5HXSA 5JDGA 3AT7A 2X0CA 5JDFA 3V5UA 3WURA 1SJ7A 5HXRA 5JDLA 4ONRA 5JDQA 4ECGA 5HXEA 3M1CA 2KBBA 3V5SA 5HYAA 5JDHA 5T1DA 5FZTA 4F7GB 2KVPA 2KGXA 2LQUA 2L10A 3AY5A 3DYJA 3PHF1 4BGOA 5JDMA 2L7NA
chains in the Genus database with same CATH topology
1SJ7A 1SJ8A 5FZTA 4F7GB 4W8PA 2KVPA 2KGXA 3DYJA 2L10A 3AY5A 3FYQA 2X0CA 2L7NA 2KBBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1SJ7 A;  1SJ8 A;  5FZT A;  4F7G B;  4W8P A;  2KVP A;  2KGX A;  3DYJ A;  2L10 A;  3AY5 A;  3FYQ A;  2X0C A;  2L7N A;  2KBB A; 
#chains in the Genus database with same CATH topology
 5HXC A;  5HWY A;  3VJZ A;  1SJ8 A;  4W8P A;  3FYQ A;  5HWX A;  3PF0 A;  2XQY A;  5JDN A;  3WSC A;  2MTC A;  5HXH A;  5HXS A;  5JDG A;  3AT7 A;  2X0C A;  5JDF A;  3V5U A;  3WUR A;  1SJ7 A;  5HXR A;  5JDL A;  4ONR A;  5JDQ A;  4ECG A;  5HXE A;  3M1C A;  2KBB A;  3V5S A;  5HYA A;  5JDH A;  5T1D A;  5FZT A;  4F7G B;  2KVP A;  2KGX A;  2LQU A;  2L10 A;  3AY5 A;  3DYJ A;  3PHF 1;  4BGO A;  5JDM A;  2L7N A; 
#chains in the Genus database with same CATH homology
 1SJ7 A;  1SJ8 A;  5FZT A;  4F7G B;  4W8P A;  2KVP A;  2KGX A;  3DYJ A;  2L10 A;  3AY5 A;  3FYQ A;  2X0C A;  2L7N A;  2KBB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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