2L7NA

Nmr structure of the b domain of talin
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
168
structure length
168
Chain Sequence
GIDPFTGPLEMDSALSVVQNLEKDLQEIKAAARDGKLKPLPGETMEKCTQDLGNSTKAVSSAIAKLLGEIAQGNENYAGIAARDVAGGLRSLAQAARGVAALTSDPAVQAIVLDTASDVLDKASSLIEEAKKASGHPGDPESQQRLAQVAKAVTQALNRCVSCLPGQR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title RIAM and vinculin binding to talin are mutually exclusive and regulate adhesion assembly and turnover.
pubmed doi rcsb
molecule keywords Talin-1
molecule tags Structural protein
source organism Mus musculus
total genus 69
structure length 168
sequence length 168
ec nomenclature
pdb deposition date 2010-12-14
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1420.10 Mainly Alpha Up-down Bundle A middle domain of Talin 1 Talin, central domain 2l7nA00
2KBBA 2KVPA 3AY5A 3FYQA 2L10A 3DYJA 4F7GB 2L7NA 5FZTA 2X0CA 4W8PA 2KGXA 1SJ7A 1SJ8A
chains in the Genus database with same CATH superfamily
2XQYA 2KBBA 2KVPA 3FYQA 5T1DA 3DYJA 5HXSA 5HXHA 5HXEA 1SJ7A 2X0CA 3PF0A 5JDHA 3VJZA 5HWYA 2L10A 4F7GB 3V5UA 3AT7A 4ECGA 4BGOA 5JDFA 5HYAA 5HWXA 2L7NA 5JDLA 4W8PA 3M1CA 3WSCA 1SJ8A 3WURA 5JDNA 4ONRA 5JDMA 3AY5A 5HXCA 5JDQA 2LQUA 2MTCA 5FZTA 3PHF1 5JDGA 3V5SA 2KGXA 5HXRA
chains in the Genus database with same CATH topology
2KBBA 2KVPA 3AY5A 3FYQA 2L10A 3DYJA 4F7GB 2L7NA 5FZTA 2X0CA 4W8PA 2KGXA 1SJ7A 1SJ8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KBB A;  2KVP A;  3AY5 A;  3FYQ A;  2L10 A;  3DYJ A;  4F7G B;  2L7N A;  5FZT A;  2X0C A;  4W8P A;  2KGX A;  1SJ7 A;  1SJ8 A; 
#chains in the Genus database with same CATH topology
 2XQY A;  2KBB A;  2KVP A;  3FYQ A;  5T1D A;  3DYJ A;  5HXS A;  5HXH A;  5HXE A;  1SJ7 A;  2X0C A;  3PF0 A;  5JDH A;  3VJZ A;  5HWY A;  2L10 A;  4F7G B;  3V5U A;  3AT7 A;  4ECG A;  4BGO A;  5JDF A;  5HYA A;  5HWX A;  2L7N A;  5JDL A;  4W8P A;  3M1C A;  3WSC A;  1SJ8 A;  3WUR A;  5JDN A;  4ONR A;  5JDM A;  3AY5 A;  5HXC A;  5JDQ A;  2LQU A;  2MTC A;  5FZT A;  3PHF 1;  5JDG A;  3V5S A;  2KGX A;  5HXR A; 
#chains in the Genus database with same CATH homology
 2KBB A;  2KVP A;  3AY5 A;  3FYQ A;  2L10 A;  3DYJ A;  4F7G B;  2L7N A;  5FZT A;  2X0C A;  4W8P A;  2KGX A;  1SJ7 A;  1SJ8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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