2LC3A

Solution nmr structure of a helical bundle domain from human e3 ligase hectd1. northeast structural genomics consortium (nesg) target ht6305a
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
88
structure length
88
Chain Sequence
MKDSDKEKENGKMGCWSIEHVEQYLGTDELPKNDLITYLQKNADAAFLRHWKLTGTNKSIRKNRNCSQLIAAYKDFCEHGTKSGLNQG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title NMR solution structure of a helical bundle from the E3 ligase HECTD1
rcsb
molecule tags Ligase
source organism Homo sapiens
molecule keywords E3 ubiquitin-protein ligase HECTD1
total genus 21
structure length 88
sequence length 88
ec nomenclature ec 2.3.2.26: HECT-type E3 ubiquitin transferase.
pdb deposition date 2011-04-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF18410 BTHB Basic tilted helix bundle domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.720.80 Mainly Alpha Orthogonal Bundle Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 2lc3A00
2KFVA 2MPHA 2LC3A
chains in the Genus database with same CATH superfamily
1A63A 2JVWA 2ODCI 1KHCA 2G80A 1GJJA 2KVUA 2MPHA 2LD7A 1JEQA 2ODGC 2W51A 2QNCA 1H9FA 1EN7A 3FLGA 2LC3A 2RNOA 3L0OA 2QNFA 1A8VA 4UZWA 1JJRA 1E7LA 1ZS9A 2KVDA 2RNNA 2DK4A 2WQGA 1GL9B 1Y02A 2KW9A 1ZBHA 1H9EA 1V66A 2HJQA 3LLRA 1GKUB 1A62A 2KFVA 1E7DA 1YNSA 2A8VA 4BITA 5CIUA 1JEIA 1H1JS 2KVEA 3QKJA
chains in the Genus database with same CATH topology
1A63A 2ODCI 2G80A 1GJJA 2MPHA 2LD7A 2ODGC 2W51A 2QNCA 1H9FA 1EN7A 2LC3A 3L0OA 2QNFA 1A8VA 1E7LA 1ZS9A 2DK4A 1GL9B 1Y02A 1H9EA 2HJQA 1GKUB 1A62A 2KFVA 1E7DA 1YNSA 2A8VA 1JEIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KFV A;  2MPH A;  2LC3 A; 
#chains in the Genus database with same CATH topology
 1A63 A;  2JVW A;  2ODC I;  1KHC A;  2G80 A;  1GJJ A;  2KVU A;  2MPH A;  2LD7 A;  1JEQ A;  2ODG C;  2W51 A;  2QNC A;  1H9F A;  1EN7 A;  3FLG A;  2LC3 A;  2RNO A;  3L0O A;  2QNF A;  1A8V A;  4UZW A;  1JJR A;  1E7L A;  1ZS9 A;  2KVD A;  2RNN A;  2DK4 A;  2WQG A;  1GL9 B;  1Y02 A;  2KW9 A;  1ZBH A;  1H9E A;  1V66 A;  2HJQ A;  3LLR A;  1GKU B;  1A62 A;  2KFV A;  1E7D A;  1YNS A;  2A8V A;  4BIT A;  5CIU A;  1JEI A;  1H1J S;  2KVE A;  3QKJ A; 
#chains in the Genus database with same CATH homology
 1A63 A;  2ODC I;  2G80 A;  1GJJ A;  2MPH A;  2LD7 A;  2ODG C;  2W51 A;  2QNC A;  1H9F A;  1EN7 A;  2LC3 A;  3L0O A;  2QNF A;  1A8V A;  1E7L A;  1ZS9 A;  2DK4 A;  1GL9 B;  1Y02 A;  1H9E A;  2HJQ A;  1GKU B;  1A62 A;  2KFV A;  1E7D A;  1YNS A;  2A8V A;  1JEI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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