2LC3A

Solution nmr structure of a helical bundle domain from human e3 ligase hectd1. northeast structural genomics consortium (nesg) target ht6305a
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
88
structure length
88
Chain Sequence
MKDSDKEKENGKMGCWSIEHVEQYLGTDELPKNDLITYLQKNADAAFLRHWKLTGTNKSIRKNRNCSQLIAAYKDFCEHGTKSGLNQG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title NMR solution structure of a helical bundle from the E3 ligase HECTD1
rcsb
molecule tags Ligase
source organism Homo sapiens
molecule keywords E3 ubiquitin-protein ligase HECTD1
total genus 21
structure length 88
sequence length 88
ec nomenclature ec 2.3.2.26: HECT-type E3 ubiquitin transferase.
pdb deposition date 2011-04-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF18410 BTHB Basic tilted helix bundle domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.720.80 Mainly Alpha Orthogonal Bundle Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 2lc3A00
2KFVA 2LC3A 2MPHA
chains in the Genus database with same CATH superfamily
4UZWA 1H9EA 2KVUA 1Y02A 1V66A 5CIUA 2ODGC 1ZS9A 1E7LA 3FLGA 2MPHA 2KW9A 2QNCA 1GKUB 2HJQA 3L0OA 2G80A 2RNNA 2WQGA 3LLRA 3QKJA 2DK4A 1JJRA 1JEQA 2KFVA 2QNFA 1A63A 1EN7A 1ZBHA 2KVDA 1A62A 2A8VA 1GL9B 1A8VA 1KHCA 4BITA 1E7DA 1H9FA 2LC3A 1H1JS 1YNSA 2W51A 1JEIA 1GJJA 2ODCI 2LD7A 2KVEA 2JVWA 2RNOA
chains in the Genus database with same CATH topology
1H9EA 1Y02A 2ODGC 1ZS9A 1E7LA 2MPHA 2QNCA 1GKUB 2HJQA 3L0OA 2G80A 2DK4A 2KFVA 2QNFA 1A63A 1EN7A 1A62A 2A8VA 1GL9B 1A8VA 1E7DA 1H9FA 2LC3A 1YNSA 2W51A 1GJJA 2ODCI 2LD7A 1JEIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KFV A;  2LC3 A;  2MPH A; 
#chains in the Genus database with same CATH topology
 4UZW A;  1H9E A;  2KVU A;  1Y02 A;  1V66 A;  5CIU A;  2ODG C;  1ZS9 A;  1E7L A;  3FLG A;  2MPH A;  2KW9 A;  2QNC A;  1GKU B;  2HJQ A;  3L0O A;  2G80 A;  2RNN A;  2WQG A;  3LLR A;  3QKJ A;  2DK4 A;  1JJR A;  1JEQ A;  2KFV A;  2QNF A;  1A63 A;  1EN7 A;  1ZBH A;  2KVD A;  1A62 A;  2A8V A;  1GL9 B;  1A8V A;  1KHC A;  4BIT A;  1E7D A;  1H9F A;  2LC3 A;  1H1J S;  1YNS A;  2W51 A;  1JEI A;  1GJJ A;  2ODC I;  2LD7 A;  2KVE A;  2JVW A;  2RNO A; 
#chains in the Genus database with same CATH homology
 1H9E A;  1Y02 A;  2ODG C;  1ZS9 A;  1E7L A;  2MPH A;  2QNC A;  1GKU B;  2HJQ A;  3L0O A;  2G80 A;  2DK4 A;  2KFV A;  2QNF A;  1A63 A;  1EN7 A;  1A62 A;  2A8V A;  1GL9 B;  1A8V A;  1E7D A;  1H9F A;  2LC3 A;  1YNS A;  2W51 A;  1GJJ A;  2ODC I;  2LD7 A;  1JEI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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