3AY5A

Crystal structure of hhm (human homologue of murine maternal id-like molecule)
Total Genus 122
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
122
sequence length
347
structure length
298
Chain Sequence
LASPLEQLRHLAEELRLLLPRVRVGEATEEFNREMFWRRLNEAAVTVSREATTLTIVFSQLPLPSPQETQKFCEQVHAAIKAFIAVYYLLPKDQGITLRKLVRGATLDIVDGMAQLMEVLSVNSVWVACQQMPQIPRDNKAAALLMLTKNVDFVKDAHEEMEQAVEESDPQDLYWSEDDQELIIPCLALVRASKACLKKIRMLVAENGKKDQVAQLDDIVDISDEISPSVDDLALSIYPPMSHLTVRINSAKLVSVLKKALEITKASHVTPSWIPLLINAIDHCMNRIKELTQSELEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of a dominant-negative helix-loop-helix transcriptional regulator suggests mechanisms of autoinhibition.
pubmed doi rcsb
molecule tags Cell cycle
source organism Homo sapiens
molecule keywords Cyclin-D1-binding protein 1
total genus 122
structure length 298
sequence length 347
ec nomenclature
pdb deposition date 2011-04-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13324 GCIP Grap2 and cyclin-D-interacting
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1410.10 Mainly Alpha Up-down Bundle I/LWEQ domain I/LWEQ domain 3ay5A02
1.20.1420.10 Mainly Alpha Up-down Bundle A middle domain of Talin 1 Talin, central domain 3ay5A01
2JSWA 2X0CA 2L10A 3AY5A 2KGXA 1R0DA 4W8PA 3FYQA 1SJ8A 2L7NA 5FZTA 3DYJA 2KVPA 2KBBA 4F7GB 1SJ7A
chains in the Genus database with same CATH superfamily
3AT7A 5HXRA 4BGOA 4ONRA 3DYJA 4F7GB 5HXHA 2X0CA 5HXEA 3PF0A 3AY5A 4W8PA 2XQYA 2MTCA 5FZTA 4ECGA 2KVPA 2KBBA 5JDLA 2JSWA 2L10A 2LQUA 2KGXA 1R0DA 5HXCA 5HWXA 5JDFA 3V5SA 5T1DA 5JDHA 1SJ7A 3VJZA 5JDMA 3PHF1 5HXSA 3M1CA 3WSCA 3FYQA 1SJ8A 2L7NA 5JDQA 5JDNA 5JDGA 3V5UA 5HWYA 3WURA 5HYAA
chains in the Genus database with same CATH topology
2JSWA 2X0CA 2L10A 3AY5A 2KGXA 1R0DA 4W8PA 3FYQA 1SJ8A 2L7NA 5FZTA 3DYJA 2KVPA 2KBBA 4F7GB 1SJ7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JSW A;  2X0C A;  2L10 A;  3AY5 A;  2KGX A;  1R0D A;  4W8P A;  3FYQ A;  1SJ8 A;  2L7N A;  5FZT A;  3DYJ A;  2KVP A;  2KBB A;  4F7G B;  1SJ7 A; 
#chains in the Genus database with same CATH topology
 3AT7 A;  5HXR A;  4BGO A;  4ONR A;  3DYJ A;  4F7G B;  5HXH A;  2X0C A;  5HXE A;  3PF0 A;  3AY5 A;  4W8P A;  2XQY A;  2MTC A;  5FZT A;  4ECG A;  2KVP A;  2KBB A;  5JDL A;  2JSW A;  2L10 A;  2LQU A;  2KGX A;  1R0D A;  5HXC A;  5HWX A;  5JDF A;  3V5S A;  5T1D A;  5JDH A;  1SJ7 A;  3VJZ A;  5JDM A;  3PHF 1;  5HXS A;  3M1C A;  3WSC A;  3FYQ A;  1SJ8 A;  2L7N A;  5JDQ A;  5JDN A;  5JDG A;  3V5U A;  5HWY A;  3WUR A;  5HYA A; 
#chains in the Genus database with same CATH homology
 2JSW A;  2X0C A;  2L10 A;  3AY5 A;  2KGX A;  1R0D A;  4W8P A;  3FYQ A;  1SJ8 A;  2L7N A;  5FZT A;  3DYJ A;  2KVP A;  2KBB A;  4F7G B;  1SJ7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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