3HQMA

Structures of spop-substrate complexes: insights into molecular architectures of btb-cul3 ubiquitin ligases: spopmathx-cisbc2
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
138
structure length
135
Chain Sequence
KVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRGFLLDEANGLLPDDKLTLFCEVSVVQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases.
pubmed doi rcsb
molecule tags Protein binding, ligase
source organism Homo sapiens
molecule keywords Speckle-type POZ protein
total genus 25
structure length 135
sequence length 138
chains with identical sequence B
ec nomenclature
pdb deposition date 2009-06-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00917 MATH MATH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.210.10 Mainly Beta Sandwich Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A 3hqmA01
2F1XA 5E1TA 1LB6A 5H9MA 2FOOA 1CZYA 3IVQA 4I7CA 4X3GA 3HQHA 1D00A 3IVVA 2F1WA 2FOPA 4Z8MA 3HQLA 3IVBA 1D0AA 1CZZA 4GHUA 4GJHA 2GKWA 1CA9A 1FLKA 4C9ZA 3ZJBA 3HU6A 1KZZA 1D01A 1QSCA 1YZEA 1F3VB 3HSVA 1RF3A 1YY6A 4K8UA 4KG9A 1K2FA 1D0JA 1LB4A 1CA4A 2AN6A 1L0AA 1LB5A 3HQIA 4GWMA 4CA1A 1FLLA 4JJQA 4YSIA 4I7BA 2A25A 3MQRA 3HQMA 4I7DA 2F1YA 2XXNA 4GWNA 4O1VA 1ZMSA 2CR2A 2FOJA 4M4EA 3MQSC 2F1ZA
chains in the Genus database with same CATH superfamily
2F1XA 5E1TA 1LB6A 5H9MA 2FOOA 1CZYA 3IVQA 4I7CA 4X3GA 3HQHA 1D00A 3IVVA 2F1WA 2FOPA 4Z8MA 3HQLA 3IVBA 1D0AA 1CZZA 4GHUA 4GJHA 2GKWA 1CA9A 1FLKA 4C9ZA 3ZJBA 3HU6A 1KZZA 1D01A 1QSCA 1YZEA 1F3VB 3HSVA 1RF3A 1YY6A 4K8UA 4KG9A 1K2FA 1D0JA 1LB4A 1CA4A 2AN6A 1L0AA 1LB5A 3HQIA 4GWMA 4CA1A 1FLLA 4JJQA 4YSIA 4I7BA 2A25A 3MQRA 3HQMA 4I7DA 2F1YA 2XXNA 4GWNA 4O1VA 1ZMSA 2CR2A 2FOJA 4M4EA 3MQSC 2F1ZA
chains in the Genus database with same CATH topology
2F1XA 5E1TA 1LB6A 5H9MA 2FOOA 1CZYA 3IVQA 4I7CA 4X3GA 3HQHA 1D00A 3IVVA 2F1WA 2FOPA 4Z8MA 3HQLA 3IVBA 1D0AA 1CZZA 4GHUA 4GJHA 2GKWA 1CA9A 1FLKA 4C9ZA 3ZJBA 3HU6A 1KZZA 1D01A 1QSCA 1YZEA 1F3VB 3HSVA 1RF3A 1YY6A 4K8UA 4KG9A 1K2FA 1D0JA 1LB4A 1CA4A 2AN6A 1L0AA 1LB5A 3HQIA 4GWMA 4CA1A 1FLLA 4JJQA 4YSIA 4I7BA 2A25A 3MQRA 3HQMA 4I7DA 2F1YA 2XXNA 4GWNA 4O1VA 1ZMSA 2CR2A 2FOJA 4M4EA 3MQSC 2F1ZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2F1X A;  5E1T A;  1LB6 A;  5H9M A;  2FOO A;  1CZY A;  3IVQ A;  4I7C A;  4X3G A;  3HQH A;  1D00 A;  3IVV A;  2F1W A;  2FOP A;  4Z8M A;  3HQL A;  3IVB A;  1D0A A;  1CZZ A;  4GHU A;  4GJH A;  2GKW A;  1CA9 A;  1FLK A;  4C9Z A;  3ZJB A;  3HU6 A;  1KZZ A;  1D01 A;  1QSC A;  1YZE A;  1F3V B;  3HSV A;  1RF3 A;  1YY6 A;  4K8U A;  4KG9 A;  1K2F A;  1D0J A;  1LB4 A;  1CA4 A;  2AN6 A;  1L0A A;  1LB5 A;  3HQI A;  4GWM A;  4CA1 A;  1FLL A;  4JJQ A;  4YSI A;  4I7B A;  2A25 A;  3MQR A;  3HQM A;  4I7D A;  2F1Y A;  2XXN A;  4GWN A;  4O1V A;  1ZMS A;  2CR2 A;  2FOJ A;  4M4E A;  3MQS C;  2F1Z A; 
#chains in the Genus database with same CATH topology
 2F1X A;  5E1T A;  1LB6 A;  5H9M A;  2FOO A;  1CZY A;  3IVQ A;  4I7C A;  4X3G A;  3HQH A;  1D00 A;  3IVV A;  2F1W A;  2FOP A;  4Z8M A;  3HQL A;  3IVB A;  1D0A A;  1CZZ A;  4GHU A;  4GJH A;  2GKW A;  1CA9 A;  1FLK A;  4C9Z A;  3ZJB A;  3HU6 A;  1KZZ A;  1D01 A;  1QSC A;  1YZE A;  1F3V B;  3HSV A;  1RF3 A;  1YY6 A;  4K8U A;  4KG9 A;  1K2F A;  1D0J A;  1LB4 A;  1CA4 A;  2AN6 A;  1L0A A;  1LB5 A;  3HQI A;  4GWM A;  4CA1 A;  1FLL A;  4JJQ A;  4YSI A;  4I7B A;  2A25 A;  3MQR A;  3HQM A;  4I7D A;  2F1Y A;  2XXN A;  4GWN A;  4O1V A;  1ZMS A;  2CR2 A;  2FOJ A;  4M4E A;  3MQS C;  2F1Z A; 
#chains in the Genus database with same CATH homology
 2F1X A;  5E1T A;  1LB6 A;  5H9M A;  2FOO A;  1CZY A;  3IVQ A;  4I7C A;  4X3G A;  3HQH A;  1D00 A;  3IVV A;  2F1W A;  2FOP A;  4Z8M A;  3HQL A;  3IVB A;  1D0A A;  1CZZ A;  4GHU A;  4GJH A;  2GKW A;  1CA9 A;  1FLK A;  4C9Z A;  3ZJB A;  3HU6 A;  1KZZ A;  1D01 A;  1QSC A;  1YZE A;  1F3V B;  3HSV A;  1RF3 A;  1YY6 A;  4K8U A;  4KG9 A;  1K2F A;  1D0J A;  1LB4 A;  1CA4 A;  2AN6 A;  1L0A A;  1LB5 A;  3HQI A;  4GWM A;  4CA1 A;  1FLL A;  4JJQ A;  4YSI A;  4I7B A;  2A25 A;  3MQR A;  3HQM A;  4I7D A;  2F1Y A;  2XXN A;  4GWN A;  4O1V A;  1ZMS A;  2CR2 A;  2FOJ A;  4M4E A;  3MQS C;  2F1Z A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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