The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
129
|
sequence length |
415
|
structure length |
415
|
Chain Sequence |
ESKVVVPAQGKKITLQNGKLNVPENPIIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAETLDLIREYRVAIKGPLTTPVGGGIRSLNVALRQELDLYICLRPVRYYQGTPSPVKHPELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVGGIGIAPGANIGDECALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRHMGWTEAADLIVKGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAIIENM
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
publication title |
Structure of the bifunctional isocitrate dehydrogenase kinase/phosphatase.
pubmed doi rcsb |
molecule tags |
Transferase, hydrolase
|
source organism |
Escherichia coli
|
molecule keywords |
Isocitrate dehydrogenase kinase/phosphatase
|
total genus |
129
|
structure length |
415
|
sequence length |
415
|
chains with identical sequence |
D
|
ec nomenclature |
ec
1.1.1.42: Isocitrate dehydrogenase (NADP(+)). |
pdb deposition date | 2010-01-10 |
chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
---|---|---|---|
C | PF00180 | Iso_dh | Isocitrate/isopropylmalate dehydrogenase |
cath code
| Class | Architecture | Topology | Homology | Domain |
---|---|---|---|---|---|
Alpha Beta | 3-Layer(aba) Sandwich | Isopropylmalate Dehydrogenase | Isopropylmalate Dehydrogenase |
#chains in the Genus database with same CATH superfamily 5GRE A; 1IDE A; 3AH3 A; 4AOY A; 7ICD A; 3US8 A; 2Y42 A; 5GRI A; 2G4O A; 4L03 A; 4KZO A; 1YCO A; 5HN4 A; 4AOV A; 1SJS A; 2UXQ A; 1DR0 A; 2QFW A; 3ASJ A; 1CNZ A; 1V53 A; 2ZTW A; 1AI2 A; 1PB1 A; 1BL5 A; 1W0D A; 3TSN A; 3WZX A; 5GRH A; 1T09 A; 4XRX A; 1DPZ A; 1VLC A; 5I96 A; 5GRF B; 3WZY A; 4UMY A; 5I95 A; 2Y3Z A; 3BLX B; 4F7I A; 1XAD A; 4ICD A; 4AJS A; 4AOU A; 1TYO A; 3ICD A; 5ICD A; 1IPD A; 5J34 A; 1CW7 A; 9ICD A; 1V94 A; 1ZOR A; 1V5B A; 3VL4 A; 1IKA A; 1HJ6 A; 3DMS A; 3FLK A; 5GRL B; 3VL6 A; 4JA8 A; 1A05 A; 1OSI A; 8ICD A; 1PS6 A; 5LGE A; 1DR8 A; 4Y1P A; 3TY4 A; 2AYQ A; 3UDU A; 3VL7 A; 5J32 A; 5J33 A; 3MAS B; 4AJC A; 3TY3 A; 1VI1 A; 4I3K A; 3R8W A; 4AJA A; 3BLV A; 3LXY A; 2DHT A; 1IDD A; 1WPW A; 1OSJ A; 4YB4 A; 5K11 A; 3MAP A; 1PB3 A; 4L06 A; 1GRO A; 4XS3 A; 1X0L A; 5GRF A; 2UXR A; 5L57 A; 3BLX A; 3UF6 A; 2QFX A; 2E0C A; 2Y41 A; 1G2U A; 1IDM A; 3WZV A; 1GC8 A; 2IV0 A; 1P8F A; 1XGV A; 5HN6 A; 6ICD A; 5HN5 A; 3VML A; 1U7N A; 2E5M A; 5HN3 A; 4ATY A; 5K10 A; 2QFV A; 4BNP A; 3LCB C; 4JQP A; 2HI1 A; 1XAB A; 5GRE B; 5GRL A; 4AJB A; 1HEX A; 1WAL A; 1R8K A; 1GRP A; 5GRI B; 2D4V A; 3U9E A; 1IDF A; 1GC9 A; 3VMJ A; 1PTM A; 3MAS A; 4WUO A; 1HQS A; 1ISO A; 1PS7 A; 5L58 A; 4XXV A; 1T0L A; 3FMX X; 3VL2 A; 1CW1 A; 3TNG A; 1IDC A; 4I3L A; 1XAC A; 1XAA A; 5GRH B; 3WZW A; 3BLV B; 3VL3 A; 4P69 C; 1CM7 A; 1CW4 A; 5DE1 A; 1AI3 A; 3MAR A; 1LWD A; 4UMX A; 2D1C A; 4HCX A; 4IWH A; 1YXO A; 1XKD A; 2QFY A; 3UDO A; 3VMK A; 4L04 A; 3VKZ A; 3U1H A; 2Y40 A; 4AJ3 A; 3INM A; 4AJR A; #chains in the Genus database with same CATH topology 5GRE A; 1IDE A; 3AH3 A; 4AOY A; 7ICD A; 3US8 A; 2Y42 A; 5GRI A; 2G4O A; 4L03 A; 4KZO A; 1YCO A; 5HN4 A; 4AOV A; 1SJS A; 2UXQ A; 1DR0 A; 2QFW A; 3ASJ A; 1CNZ A; 1V53 A; 2ZTW A; 1AI2 A; 1PB1 A; 1BL5 A; 1W0D A; 3TSN A; 3WZX A; 5GRH A; 1T09 A; 4XRX A; 1DPZ A; 1VLC A; 5I96 A; 5GRF B; 3WZY A; 4UMY A; 5I95 A; 2Y3Z A; 3BLX B; 4F7I A; 1XAD A; 4ICD A; 4AJS A; 4AOU A; 1TYO A; 3ICD A; 5ICD A; 1IPD A; 5J34 A; 1CW7 A; 9ICD A; 1V94 A; 1ZOR A; 1V5B A; 3VL4 A; 1IKA A; 1HJ6 A; 3DMS A; 3FLK A; 5GRL B; 3VL6 A; 4JA8 A; 1A05 A; 1OSI A; 8ICD A; 1PS6 A; 5LGE A; 1DR8 A; 4Y1P A; 3TY4 A; 2AYQ A; 3UDU A; 3VL7 A; 5J32 A; 5J33 A; 3MAS B; 4AJC A; 3TY3 A; 1VI1 A; 4I3K A; 3R8W A; 4AJA A; 3BLV A; 3LXY A; 2DHT A; 1IDD A; 1WPW A; 1OSJ A; 4YB4 A; 5K11 A; 3MAP A; 1PB3 A; 4L06 A; 1GRO A; 4XS3 A; 1X0L A; 5GRF A; 2UXR A; 5L57 A; 3BLX A; 3UF6 A; 2QFX A; 2E0C A; 2Y41 A; 1G2U A; 1IDM A; 3WZV A; 1GC8 A; 2IV0 A; 1P8F A; 1XGV A; 5HN6 A; 6ICD A; 5HN5 A; 3VML A; 1U7N A; 2E5M A; 5HN3 A; 4ATY A; 5K10 A; 2QFV A; 4BNP A; 3LCB C; 4JQP A; 2HI1 A; 1XAB A; 5GRE B; 5GRL A; 4AJB A; 1HEX A; 1WAL A; 1R8K A; 1GRP A; 5GRI B; 2D4V A; 3U9E A; 1IDF A; 1GC9 A; 3VMJ A; 1PTM A; 3MAS A; 4WUO A; 1HQS A; 1ISO A; 1PS7 A; 5L58 A; 4XXV A; 1T0L A; 3FMX X; 3VL2 A; 1CW1 A; 3TNG A; 1IDC A; 4I3L A; 1XAC A; 1XAA A; 5GRH B; 3WZW A; 3BLV B; 3VL3 A; 4P69 C; 1CM7 A; 1CW4 A; 5DE1 A; 1AI3 A; 3MAR A; 1LWD A; 4UMX A; 2D1C A; 4HCX A; 4IWH A; 1YXO A; 1XKD A; 2QFY A; 3UDO A; 3VMK A; 4L04 A; 3VKZ A; 3U1H A; 2Y40 A; 4AJ3 A; 3INM A; 4AJR A; #chains in the Genus database with same CATH homology 5GRE A; 1IDE A; 3AH3 A; 4AOY A; 7ICD A; 3US8 A; 2Y42 A; 5GRI A; 2G4O A; 4L03 A; 4KZO A; 1YCO A; 5HN4 A; 4AOV A; 1SJS A; 2UXQ A; 1DR0 A; 2QFW A; 3ASJ A; 1CNZ A; 1V53 A; 2ZTW A; 1AI2 A; 1PB1 A; 1BL5 A; 1W0D A; 3TSN A; 3WZX A; 5GRH A; 1T09 A; 4XRX A; 1DPZ A; 1VLC A; 5I96 A; 5GRF B; 3WZY A; 4UMY A; 5I95 A; 2Y3Z A; 3BLX B; 4F7I A; 1XAD A; 4ICD A; 4AJS A; 4AOU A; 1TYO A; 3ICD A; 5ICD A; 1IPD A; 5J34 A; 1CW7 A; 9ICD A; 1V94 A; 1ZOR A; 1V5B A; 3VL4 A; 1IKA A; 1HJ6 A; 3DMS A; 3FLK A; 5GRL B; 3VL6 A; 4JA8 A; 1A05 A; 1OSI A; 8ICD A; 1PS6 A; 5LGE A; 1DR8 A; 4Y1P A; 3TY4 A; 2AYQ A; 3UDU A; 3VL7 A; 5J32 A; 5J33 A; 3MAS B; 4AJC A; 3TY3 A; 1VI1 A; 4I3K A; 3R8W A; 4AJA A; 3BLV A; 3LXY A; 2DHT A; 1IDD A; 1WPW A; 1OSJ A; 4YB4 A; 5K11 A; 3MAP A; 1PB3 A; 4L06 A; 1GRO A; 4XS3 A; 1X0L A; 5GRF A; 2UXR A; 5L57 A; 3BLX A; 3UF6 A; 2QFX A; 2E0C A; 2Y41 A; 1G2U A; 1IDM A; 3WZV A; 1GC8 A; 2IV0 A; 1P8F A; 1XGV A; 5HN6 A; 6ICD A; 5HN5 A; 3VML A; 1U7N A; 2E5M A; 5HN3 A; 4ATY A; 5K10 A; 2QFV A; 4BNP A; 3LCB C; 4JQP A; 2HI1 A; 1XAB A; 5GRE B; 5GRL A; 4AJB A; 1HEX A; 1WAL A; 1R8K A; 1GRP A; 5GRI B; 2D4V A; 3U9E A; 1IDF A; 1GC9 A; 3VMJ A; 1PTM A; 3MAS A; 4WUO A; 1HQS A; 1ISO A; 1PS7 A; 5L58 A; 4XXV A; 1T0L A; 3FMX X; 3VL2 A; 1CW1 A; 3TNG A; 1IDC A; 4I3L A; 1XAC A; 1XAA A; 5GRH B; 3WZW A; 3BLV B; 3VL3 A; 4P69 C; 1CM7 A; 1CW4 A; 5DE1 A; 1AI3 A; 3MAR A; 1LWD A; 4UMX A; 2D1C A; 4HCX A; 4IWH A; 1YXO A; 1XKD A; 2QFY A; 3UDO A; 3VMK A; 4L04 A; 3VKZ A; 3U1H A; 2Y40 A; 4AJ3 A; 3INM A; 4AJR A;
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