3MQPA

Crystal structure of human bfl-1 in complex with noxa bh3 peptide, northeast structural genomics consortium target hr2930
Total Genus 54
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
sequence length
150
structure length
150
Chain Sequence
TDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEPK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of human BFL-1 in complex with NOXA BH3 peptide
rcsb
molecule tags Apoptosis
source organism Homo sapiens
molecule keywords Bcl-2-related protein A1
total genus 54
structure length 150
sequence length 150
ec nomenclature
pdb deposition date 2010-04-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00452 Bcl-2 Apoptosis regulator proteins, Bcl-2 family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.437.10 Mainly Alpha Orthogonal Bundle Apoptosis Regulator Bcl-x Blc2-like 3mqpA00
4B4SA 4ZEQA 4QVXA 3I1HA 4ZIIA 1TY4A 1PQ1A 5C3FA 4BD2A 1O0LA 2WH6A 3PK1A 5FMIA 2JCNA 2VM6A 4ZIEA 1MK3A 2VOIA 3KZ0A 4S0OA 2IMTA 2V6QA 4BD7A 4BPJA 1YSWA 4BD8A 2LR1A 4K5BC 4QNQA 1BXLA 4MI8A 2ROCA 1R2IA 5KU9A 1WSXA 1DDBA 5FDRA 3KJ1A 3KJ2A 4HW4A 2KUAA 3IIHA 5IEZA 3IHEA 1G5MA 1R2HA 3DVUA 1G5JA 4YK9A 3MK8A 2ME8A 2IMSA 4OQ5A 2BZWA 1PQ0A 4ZBFA 1YSGA 1MAZA 3MQPA 5JSBA 2MHSA 4OQ6A 5IF4A 1AF3A 2XA0A 1R2EA 3IIGA 2O2FA 3KJ0A 5FC4A 2O22A 1YSIA 4U2VA 3IO9A 4ZIHA 2NLAA 2XPXA 4U2UA 2O21A 1LXLA 5KTGA 3QBRA 2VOFA 4HW3A 4ZIGA 3IHCA 4WMRA 2JM6B 2W3LA 2NL9A 2YV6A 1K3KA 4BDUA 5C6HA 4YJ4A 2BIDA 2VOGA 3IHDA 1ZY3A 2PQKA 2RODA 2K7WA 2KBWA 3CVAX 4OYDA 1R2GA 2B48A 1OHUA 1YSNA 2VOHA 2O2MA 4BD6A 1Q59A 4HW2A 3BL2A 5FDOA 4ZIFA 2MEJA 3WIYA 3ILCA 4BPIA 1F16A 3WIXA 2A5YA 4ZBIA 1R2DA 2O2NA 4G35A 4S0PA 3D7VA 2ABOA 1GJHA 2M5BA
chains in the Genus database with same CATH superfamily
4B4SA 4ZEQA 4QVXA 3I1HA 4ZIIA 1TY4A 1PQ1A 5C3FA 2VVWA 4BD2A 1O0LA 2WH6A 3PK1A 5FMIA 2JCNA 2VM6A 4ZIEA 1MK3A 2VOIA 3KZ0A 2VTYA 2I39A 4S0OA 4UF3A 2IMTA 2JBXA 2V6QA 4BD7A 4BPJA 1YSWA 4UF1A 4BD8A 2LR1A 4K5BC 4QNQA 1BXLA 4MI8A 4BBDA 2ROCA 1R2IA 5KU9A 1WSXA 1DDBA 5FDRA 4BBCA 3KJ1A 3KJ2A 4HW4A 2KUAA 3IIHA 5IEZA 3IHEA 1G5MA 1R2HA 4LQKA 3DVUA 1G5JA 4YK9A 3MK8A 2ME8A 2IMSA 4OQ5A 2BZWA 1PQ0A 4ZBFA 1YSGA 1MAZA 3MQPA 4UF2A 5JSBA 4D2LA 2MHSA 4OQ6A 2JBYA 5IF4A 1AF3A 2XA0A 1R2EA 2O2FA 3IIGA 3KJ0A 5FC4A 2O22A 1YSIA 4U2VA 3IO9A 4ZIHA 3JRVA 2NLAA 2XPXA 4U2UA 2O21A 1LXLA 5KTGA 3QBRA 2VOFA 4HW3A 4D2MA 4ZIGA 4M0SA 3IHCA 4WMRA 2JM6B 2W3LA 2NL9A 2YV6A 1K3KA 4BDUA 5C6HA 4YJ4A 2BIDA 2VOGA 3IHDA 1ZY3A 2PQKA 2RODA 2K7WA 2K36A 2KBWA 3CVAX 4OYDA 1R2GA 2B48A 1OHUA 1YSNA 2VOHA 2O2MA 4BD6A 1Q59A 2VVXA 4HW2A 3BL2A 5FDOA 4ZIFA 2MEJA 3WIYA 3ILCA 4BPIA 1F16A 3WIXA 2A5YA 2UXEA 4ZBIA 1R2DA 2O2NA 4BBBA 4G35A 4S0PA 2O42A 3D7VA 2ABOA 1GJHA 2M5BA 2VVYA
chains in the Genus database with same CATH topology
4B4SA 4ZEQA 4QVXA 3I1HA 4ZIIA 1TY4A 1PQ1A 5C3FA 4BD2A 1O0LA 2WH6A 3PK1A 5FMIA 2JCNA 2VM6A 4ZIEA 1MK3A 2VOIA 3KZ0A 4S0OA 2IMTA 2V6QA 4BD7A 4BPJA 1YSWA 4BD8A 2LR1A 4K5BC 4QNQA 1BXLA 4MI8A 2ROCA 1R2IA 5KU9A 1WSXA 1DDBA 5FDRA 3KJ1A 3KJ2A 4HW4A 2KUAA 3IIHA 5IEZA 3IHEA 1G5MA 1R2HA 3DVUA 1G5JA 4YK9A 3MK8A 2ME8A 2IMSA 4OQ5A 2BZWA 1PQ0A 4ZBFA 1YSGA 1MAZA 3MQPA 5JSBA 2MHSA 4OQ6A 5IF4A 1AF3A 2XA0A 1R2EA 3IIGA 2O2FA 3KJ0A 5FC4A 2O22A 1YSIA 4U2VA 3IO9A 4ZIHA 2NLAA 2XPXA 4U2UA 2O21A 1LXLA 5KTGA 3QBRA 2VOFA 4HW3A 4ZIGA 3IHCA 4WMRA 2JM6B 2W3LA 2NL9A 2YV6A 1K3KA 4BDUA 5C6HA 4YJ4A 2BIDA 2VOGA 3IHDA 1ZY3A 2PQKA 2RODA 2K7WA 2KBWA 3CVAX 4OYDA 1R2GA 2B48A 1OHUA 1YSNA 2VOHA 2O2MA 4BD6A 1Q59A 4HW2A 3BL2A 5FDOA 4ZIFA 2MEJA 3WIYA 3ILCA 4BPIA 1F16A 3WIXA 2A5YA 4ZBIA 1R2DA 2O2NA 4G35A 4S0PA 3D7VA 2ABOA 1GJHA 2M5BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4B4S A;  4ZEQ A;  4QVX A;  3I1H A;  4ZII A;  1TY4 A;  1PQ1 A;  5C3F A;  4BD2 A;  1O0L A;  2WH6 A;  3PK1 A;  5FMI A;  2JCN A;  2VM6 A;  4ZIE A;  1MK3 A;  2VOI A;  3KZ0 A;  4S0O A;  2IMT A;  2V6Q A;  4BD7 A;  4BPJ A;  1YSW A;  4BD8 A;  2LR1 A;  4K5B C;  4QNQ A;  1BXL A;  4MI8 A;  2ROC A;  1R2I A;  5KU9 A;  1WSX A;  1DDB A;  5FDR A;  3KJ1 A;  3KJ2 A;  4HW4 A;  2KUA A;  3IIH A;  5IEZ A;  3IHE A;  1G5M A;  1R2H A;  3DVU A;  1G5J A;  4YK9 A;  3MK8 A;  2ME8 A;  2IMS A;  4OQ5 A;  2BZW A;  1PQ0 A;  4ZBF A;  1YSG A;  1MAZ A;  3MQP A;  5JSB A;  2MHS A;  4OQ6 A;  5IF4 A;  1AF3 A;  2XA0 A;  1R2E A;  3IIG A;  2O2F A;  3KJ0 A;  5FC4 A;  2O22 A;  1YSI A;  4U2V A;  3IO9 A;  4ZIH A;  2NLA A;  2XPX A;  4U2U A;  2O21 A;  1LXL A;  5KTG A;  3QBR A;  2VOF A;  4HW3 A;  4ZIG A;  3IHC A;  4WMR A;  2JM6 B;  2W3L A;  2NL9 A;  2YV6 A;  1K3K A;  4BDU A;  5C6H A;  4YJ4 A;  2BID A;  2VOG A;  3IHD A;  1ZY3 A;  2PQK A;  2ROD A;  2K7W A;  2KBW A;  3CVA X;  4OYD A;  1R2G A;  2B48 A;  1OHU A;  1YSN A;  2VOH A;  2O2M A;  4BD6 A;  1Q59 A;  4HW2 A;  3BL2 A;  5FDO A;  4ZIF A;  2MEJ A;  3WIY A;  3ILC A;  4BPI A;  1F16 A;  3WIX A;  2A5Y A;  4ZBI A;  1R2D A;  2O2N A;  4G35 A;  4S0P A;  3D7V A;  2ABO A;  1GJH A;  2M5B A; 
#chains in the Genus database with same CATH topology
 4B4S A;  4ZEQ A;  4QVX A;  3I1H A;  4ZII A;  1TY4 A;  1PQ1 A;  5C3F A;  2VVW A;  4BD2 A;  1O0L A;  2WH6 A;  3PK1 A;  5FMI A;  2JCN A;  2VM6 A;  4ZIE A;  1MK3 A;  2VOI A;  3KZ0 A;  2VTY A;  2I39 A;  4S0O A;  4UF3 A;  2IMT A;  2JBX A;  2V6Q A;  4BD7 A;  4BPJ A;  1YSW A;  4UF1 A;  4BD8 A;  2LR1 A;  4K5B C;  4QNQ A;  1BXL A;  4MI8 A;  4BBD A;  2ROC A;  1R2I A;  5KU9 A;  1WSX A;  1DDB A;  5FDR A;  4BBC A;  3KJ1 A;  3KJ2 A;  4HW4 A;  2KUA A;  3IIH A;  5IEZ A;  3IHE A;  1G5M A;  1R2H A;  4LQK A;  3DVU A;  1G5J A;  4YK9 A;  3MK8 A;  2ME8 A;  2IMS A;  4OQ5 A;  2BZW A;  1PQ0 A;  4ZBF A;  1YSG A;  1MAZ A;  3MQP A;  4UF2 A;  5JSB A;  4D2L A;  2MHS A;  4OQ6 A;  2JBY A;  5IF4 A;  1AF3 A;  2XA0 A;  1R2E A;  2O2F A;  3IIG A;  3KJ0 A;  5FC4 A;  2O22 A;  1YSI A;  4U2V A;  3IO9 A;  4ZIH A;  3JRV A;  2NLA A;  2XPX A;  4U2U A;  2O21 A;  1LXL A;  5KTG A;  3QBR A;  2VOF A;  4HW3 A;  4D2M A;  4ZIG A;  4M0S A;  3IHC A;  4WMR A;  2JM6 B;  2W3L A;  2NL9 A;  2YV6 A;  1K3K A;  4BDU A;  5C6H A;  4YJ4 A;  2BID A;  2VOG A;  3IHD A;  1ZY3 A;  2PQK A;  2ROD A;  2K7W A;  2K36 A;  2KBW A;  3CVA X;  4OYD A;  1R2G A;  2B48 A;  1OHU A;  1YSN A;  2VOH A;  2O2M A;  4BD6 A;  1Q59 A;  2VVX A;  4HW2 A;  3BL2 A;  5FDO A;  4ZIF A;  2MEJ A;  3WIY A;  3ILC A;  4BPI A;  1F16 A;  3WIX A;  2A5Y A;  2UXE A;  4ZBI A;  1R2D A;  2O2N A;  4BBB A;  4G35 A;  4S0P A;  2O42 A;  3D7V A;  2ABO A;  1GJH A;  2M5B A;  2VVY A; 
#chains in the Genus database with same CATH homology
 4B4S A;  4ZEQ A;  4QVX A;  3I1H A;  4ZII A;  1TY4 A;  1PQ1 A;  5C3F A;  4BD2 A;  1O0L A;  2WH6 A;  3PK1 A;  5FMI A;  2JCN A;  2VM6 A;  4ZIE A;  1MK3 A;  2VOI A;  3KZ0 A;  4S0O A;  2IMT A;  2V6Q A;  4BD7 A;  4BPJ A;  1YSW A;  4BD8 A;  2LR1 A;  4K5B C;  4QNQ A;  1BXL A;  4MI8 A;  2ROC A;  1R2I A;  5KU9 A;  1WSX A;  1DDB A;  5FDR A;  3KJ1 A;  3KJ2 A;  4HW4 A;  2KUA A;  3IIH A;  5IEZ A;  3IHE A;  1G5M A;  1R2H A;  3DVU A;  1G5J A;  4YK9 A;  3MK8 A;  2ME8 A;  2IMS A;  4OQ5 A;  2BZW A;  1PQ0 A;  4ZBF A;  1YSG A;  1MAZ A;  3MQP A;  5JSB A;  2MHS A;  4OQ6 A;  5IF4 A;  1AF3 A;  2XA0 A;  1R2E A;  3IIG A;  2O2F A;  3KJ0 A;  5FC4 A;  2O22 A;  1YSI A;  4U2V A;  3IO9 A;  4ZIH A;  2NLA A;  2XPX A;  4U2U A;  2O21 A;  1LXL A;  5KTG A;  3QBR A;  2VOF A;  4HW3 A;  4ZIG A;  3IHC A;  4WMR A;  2JM6 B;  2W3L A;  2NL9 A;  2YV6 A;  1K3K A;  4BDU A;  5C6H A;  4YJ4 A;  2BID A;  2VOG A;  3IHD A;  1ZY3 A;  2PQK A;  2ROD A;  2K7W A;  2KBW A;  3CVA X;  4OYD A;  1R2G A;  2B48 A;  1OHU A;  1YSN A;  2VOH A;  2O2M A;  4BD6 A;  1Q59 A;  4HW2 A;  3BL2 A;  5FDO A;  4ZIF A;  2MEJ A;  3WIY A;  3ILC A;  4BPI A;  1F16 A;  3WIX A;  2A5Y A;  4ZBI A;  1R2D A;  2O2N A;  4G35 A;  4S0P A;  3D7V A;  2ABO A;  1GJH A;  2M5B A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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