3TY3A

Crystal structure of homoisocitrate dehydrogenase from schizosaccharomyces pombe bound to glycyl-glycyl-glycine
Total Genus 124
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
124
sequence length
358
structure length
358
Chain Sequence
RRIVLGLIPADGIGKEVVPAARRLMENLPAKHKLKFDFIDLDAGWGTFERTGKALPERTVERLKTECNAALFGAVQSPTHKVAGYSSPIVALRKKMGLYANVRPVKSLDGAKGKPVDLVIVRENTECLYVKEERMVQNTPGKRVAEAIRRISEEASTKIGKMAFEIAKSRQKIRESGTYSIHKKPLVTIIHKSNVMSVTDGLFRESCRHAQSLDPSYASINVDEQIVDSMVYRLFREPECFDVVVAPNLYGDILSDGAASLIGSLGLVPSANVGDNFVMSEPVHGSAPDIAGRGIANPVATFRSVALMLEFMGHQDAAADIYTAVDKVLTEGKVLTPDLGGKSGTNEITDAVLANIHN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of homoisocitrate dehydrogenase from Schizosaccharomyces pombe.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Schizosaccharomyces pombe
molecule keywords Probable homoisocitrate dehydrogenase
total genus 124
structure length 358
sequence length 358
chains with identical sequence B
ec nomenclature ec 1.1.1.87: Homoisocitrate dehydrogenase.
pdb deposition date 2011-09-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00180 Iso_dh Isocitrate/isopropylmalate dehydrogenase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.718.10 Alpha Beta 3-Layer(aba) Sandwich Isopropylmalate Dehydrogenase Isopropylmalate Dehydrogenase 3ty3A00
9ICDA 3R8WA 1WALA 4UMXA 2UXRA 4P69C 5J32A 1X0LA 1VLCA 4Y1PA 3VL2A 1IPDA 3INMA 3BLVA 1GC8A 1CW4A 5GRIA 3UF6A 3AH3A 4XRXA 1XACA 4AJAA 5GRHB 3WZWA 4L06A 2HI1A 3MASB 3VMJA 3VL4A 5GREB 3UDOA 1IDMA 1PB3A 3U9EA 5K10A 8ICDA 1GROA 3BLXA 2IV0A 4XS3A 5HN3A 1OSIA 1IDEA 4JQPA 3LCBC 1A05A 1U7NA 4I3KA 5GRLB 3U1HA 3TSNA 2E0CA 1HQSA 3VL6A 5K11A 1HJ6A 3FMXX 3VL7A 3MARA 1CNZA 1T09A 5HN4A 1BL5A 5HN5A 2Y41A 3ICDA 4F7IA 5I95A 1VI1A 2D1CA 1HEXA 1YXOA 5I96A 3TY3A 1ISOA 1XGVA 4HCXA 4XXVA 1IDFA 3FLKA 1P8FA 4AOVA 1GC9A 4AJBA 1AI3A 3DMSA 5J34A 5L58A 2Y42A 5J33A 5HN6A 3US8A 1DPZA 2QFYA 1R8KA 4JA8A 4L04A 3VL3A 4ATYA 5GRFA 3UDUA 5L57A 5LGEA 3VKZA 2E5MA 1CW7A 2ZTWA 3VMLA 1YCOA 1PS7A 1CM7A 3VMKA 4AJ3A 4ICDA 3BLVB 3LXYA 2QFVA 5GRIB 3TNGA 1SJSA 1TYOA 2G4OA 4UMYA 1CW1A 2Y40A 5GRHA 1XAAA 2DHTA 3MAPA 3MASA 2AYQA 1W0DA 4KZOA 4L03A 4AJRA 5GREA 3BLXB 1PS6A 4BNPA 3TY4A 1OSJA 4YB4A 5DE1A 1IKAA 2QFWA 1XKDA 4I3LA 1IDDA 1V94A 1XADA 4AOYA 1IDCA 2UXQA 6ICDA 7ICDA 5GRLA 1V5BA 3WZVA 3WZYA 2Y3ZA 4WUOA 4AOUA 1AI2A 2D4VA 1ZORA 1T0LA 1DR8A 5ICDA 3WZXA 3ASJA 1GRPA 1LWDA 4IWHA 1WPWA 1G2UA 4AJSA 1V53A 5GRFB 1PB1A 2QFXA 4AJCA 1XABA 1PTMA 1DR0A
chains in the Genus database with same CATH superfamily
9ICDA 3R8WA 1WALA 4UMXA 2UXRA 4P69C 5J32A 1X0LA 1VLCA 4Y1PA 3VL2A 1IPDA 3INMA 3BLVA 1GC8A 1CW4A 5GRIA 3UF6A 3AH3A 4XRXA 1XACA 4AJAA 5GRHB 3WZWA 4L06A 2HI1A 3MASB 3VMJA 3VL4A 5GREB 3UDOA 1IDMA 1PB3A 3U9EA 5K10A 8ICDA 1GROA 3BLXA 2IV0A 4XS3A 5HN3A 1OSIA 1IDEA 4JQPA 3LCBC 1A05A 1U7NA 4I3KA 5GRLB 3U1HA 3TSNA 2E0CA 1HQSA 3VL6A 5K11A 1HJ6A 3FMXX 3VL7A 3MARA 1CNZA 1T09A 5HN4A 1BL5A 5HN5A 2Y41A 3ICDA 4F7IA 5I95A 1VI1A 2D1CA 1HEXA 1YXOA 5I96A 3TY3A 1ISOA 1XGVA 4HCXA 4XXVA 1IDFA 3FLKA 1P8FA 4AOVA 1GC9A 4AJBA 1AI3A 3DMSA 5J34A 5L58A 2Y42A 5J33A 5HN6A 3US8A 1DPZA 2QFYA 1R8KA 4JA8A 4L04A 3VL3A 4ATYA 5GRFA 3UDUA 5L57A 5LGEA 3VKZA 2E5MA 1CW7A 2ZTWA 3VMLA 1YCOA 1PS7A 1CM7A 3VMKA 4AJ3A 4ICDA 3BLVB 3LXYA 2QFVA 5GRIB 3TNGA 1SJSA 1TYOA 2G4OA 4UMYA 1CW1A 2Y40A 5GRHA 1XAAA 2DHTA 3MAPA 3MASA 2AYQA 1W0DA 4KZOA 4L03A 4AJRA 5GREA 3BLXB 1PS6A 4BNPA 3TY4A 1OSJA 4YB4A 5DE1A 1IKAA 2QFWA 1XKDA 4I3LA 1IDDA 1V94A 1XADA 4AOYA 1IDCA 2UXQA 6ICDA 7ICDA 5GRLA 1V5BA 3WZVA 3WZYA 2Y3ZA 4WUOA 4AOUA 1AI2A 2D4VA 1ZORA 1T0LA 1DR8A 5ICDA 3WZXA 3ASJA 1GRPA 1LWDA 4IWHA 1WPWA 1G2UA 4AJSA 1V53A 5GRFB 1PB1A 2QFXA 4AJCA 1XABA 1PTMA 1DR0A
chains in the Genus database with same CATH topology
9ICDA 3R8WA 1WALA 4UMXA 2UXRA 4P69C 5J32A 1X0LA 1VLCA 4Y1PA 3VL2A 1IPDA 3INMA 3BLVA 1GC8A 1CW4A 5GRIA 3UF6A 3AH3A 4XRXA 1XACA 4AJAA 5GRHB 3WZWA 4L06A 2HI1A 3MASB 3VMJA 3VL4A 5GREB 3UDOA 1IDMA 1PB3A 3U9EA 5K10A 8ICDA 1GROA 3BLXA 2IV0A 4XS3A 5HN3A 1OSIA 1IDEA 4JQPA 3LCBC 1A05A 1U7NA 4I3KA 5GRLB 3U1HA 3TSNA 2E0CA 1HQSA 3VL6A 5K11A 1HJ6A 3FMXX 3VL7A 3MARA 1CNZA 1T09A 5HN4A 1BL5A 5HN5A 2Y41A 3ICDA 4F7IA 5I95A 1VI1A 2D1CA 1HEXA 1YXOA 5I96A 3TY3A 1ISOA 1XGVA 4HCXA 4XXVA 1IDFA 3FLKA 1P8FA 4AOVA 1GC9A 4AJBA 1AI3A 3DMSA 5J34A 5L58A 2Y42A 5J33A 5HN6A 3US8A 1DPZA 2QFYA 1R8KA 4JA8A 4L04A 3VL3A 4ATYA 5GRFA 3UDUA 5L57A 5LGEA 3VKZA 2E5MA 1CW7A 2ZTWA 3VMLA 1YCOA 1PS7A 1CM7A 3VMKA 4AJ3A 4ICDA 3BLVB 3LXYA 2QFVA 5GRIB 3TNGA 1SJSA 1TYOA 2G4OA 4UMYA 1CW1A 2Y40A 5GRHA 1XAAA 2DHTA 3MAPA 3MASA 2AYQA 1W0DA 4KZOA 4L03A 4AJRA 5GREA 3BLXB 1PS6A 4BNPA 3TY4A 1OSJA 4YB4A 5DE1A 1IKAA 2QFWA 1XKDA 4I3LA 1IDDA 1V94A 1XADA 4AOYA 1IDCA 2UXQA 6ICDA 7ICDA 5GRLA 1V5BA 3WZVA 3WZYA 2Y3ZA 4WUOA 4AOUA 1AI2A 2D4VA 1ZORA 1T0LA 1DR8A 5ICDA 3WZXA 3ASJA 1GRPA 1LWDA 4IWHA 1WPWA 1G2UA 4AJSA 1V53A 5GRFB 1PB1A 2QFXA 4AJCA 1XABA 1PTMA 1DR0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 9ICD A;  3R8W A;  1WAL A;  4UMX A;  2UXR A;  4P69 C;  5J32 A;  1X0L A;  1VLC A;  4Y1P A;  3VL2 A;  1IPD A;  3INM A;  3BLV A;  1GC8 A;  1CW4 A;  5GRI A;  3UF6 A;  3AH3 A;  4XRX A;  1XAC A;  4AJA A;  5GRH B;  3WZW A;  4L06 A;  2HI1 A;  3MAS B;  3VMJ A;  3VL4 A;  5GRE B;  3UDO A;  1IDM A;  1PB3 A;  3U9E A;  5K10 A;  8ICD A;  1GRO A;  3BLX A;  2IV0 A;  4XS3 A;  5HN3 A;  1OSI A;  1IDE A;  4JQP A;  3LCB C;  1A05 A;  1U7N A;  4I3K A;  5GRL B;  3U1H A;  3TSN A;  2E0C A;  1HQS A;  3VL6 A;  5K11 A;  1HJ6 A;  3FMX X;  3VL7 A;  3MAR A;  1CNZ A;  1T09 A;  5HN4 A;  1BL5 A;  5HN5 A;  2Y41 A;  3ICD A;  4F7I A;  5I95 A;  1VI1 A;  2D1C A;  1HEX A;  1YXO A;  5I96 A;  3TY3 A;  1ISO A;  1XGV A;  4HCX A;  4XXV A;  1IDF A;  3FLK A;  1P8F A;  4AOV A;  1GC9 A;  4AJB A;  1AI3 A;  3DMS A;  5J34 A;  5L58 A;  2Y42 A;  5J33 A;  5HN6 A;  3US8 A;  1DPZ A;  2QFY A;  1R8K A;  4JA8 A;  4L04 A;  3VL3 A;  4ATY A;  5GRF A;  3UDU A;  5L57 A;  5LGE A;  3VKZ A;  2E5M A;  1CW7 A;  2ZTW A;  3VML A;  1YCO A;  1PS7 A;  1CM7 A;  3VMK A;  4AJ3 A;  4ICD A;  3BLV B;  3LXY A;  2QFV A;  5GRI B;  3TNG A;  1SJS A;  1TYO A;  2G4O A;  4UMY A;  1CW1 A;  2Y40 A;  5GRH A;  1XAA A;  2DHT A;  3MAP A;  3MAS A;  2AYQ A;  1W0D A;  4KZO A;  4L03 A;  4AJR A;  5GRE A;  3BLX B;  1PS6 A;  4BNP A;  3TY4 A;  1OSJ A;  4YB4 A;  5DE1 A;  1IKA A;  2QFW A;  1XKD A;  4I3L A;  1IDD A;  1V94 A;  1XAD A;  4AOY A;  1IDC A;  2UXQ A;  6ICD A;  7ICD A;  5GRL A;  1V5B A;  3WZV A;  3WZY A;  2Y3Z A;  4WUO A;  4AOU A;  1AI2 A;  2D4V A;  1ZOR A;  1T0L A;  1DR8 A;  5ICD A;  3WZX A;  3ASJ A;  1GRP A;  1LWD A;  4IWH A;  1WPW A;  1G2U A;  4AJS A;  1V53 A;  5GRF B;  1PB1 A;  2QFX A;  4AJC A;  1XAB A;  1PTM A;  1DR0 A; 
#chains in the Genus database with same CATH topology
 9ICD A;  3R8W A;  1WAL A;  4UMX A;  2UXR A;  4P69 C;  5J32 A;  1X0L A;  1VLC A;  4Y1P A;  3VL2 A;  1IPD A;  3INM A;  3BLV A;  1GC8 A;  1CW4 A;  5GRI A;  3UF6 A;  3AH3 A;  4XRX A;  1XAC A;  4AJA A;  5GRH B;  3WZW A;  4L06 A;  2HI1 A;  3MAS B;  3VMJ A;  3VL4 A;  5GRE B;  3UDO A;  1IDM A;  1PB3 A;  3U9E A;  5K10 A;  8ICD A;  1GRO A;  3BLX A;  2IV0 A;  4XS3 A;  5HN3 A;  1OSI A;  1IDE A;  4JQP A;  3LCB C;  1A05 A;  1U7N A;  4I3K A;  5GRL B;  3U1H A;  3TSN A;  2E0C A;  1HQS A;  3VL6 A;  5K11 A;  1HJ6 A;  3FMX X;  3VL7 A;  3MAR A;  1CNZ A;  1T09 A;  5HN4 A;  1BL5 A;  5HN5 A;  2Y41 A;  3ICD A;  4F7I A;  5I95 A;  1VI1 A;  2D1C A;  1HEX A;  1YXO A;  5I96 A;  3TY3 A;  1ISO A;  1XGV A;  4HCX A;  4XXV A;  1IDF A;  3FLK A;  1P8F A;  4AOV A;  1GC9 A;  4AJB A;  1AI3 A;  3DMS A;  5J34 A;  5L58 A;  2Y42 A;  5J33 A;  5HN6 A;  3US8 A;  1DPZ A;  2QFY A;  1R8K A;  4JA8 A;  4L04 A;  3VL3 A;  4ATY A;  5GRF A;  3UDU A;  5L57 A;  5LGE A;  3VKZ A;  2E5M A;  1CW7 A;  2ZTW A;  3VML A;  1YCO A;  1PS7 A;  1CM7 A;  3VMK A;  4AJ3 A;  4ICD A;  3BLV B;  3LXY A;  2QFV A;  5GRI B;  3TNG A;  1SJS A;  1TYO A;  2G4O A;  4UMY A;  1CW1 A;  2Y40 A;  5GRH A;  1XAA A;  2DHT A;  3MAP A;  3MAS A;  2AYQ A;  1W0D A;  4KZO A;  4L03 A;  4AJR A;  5GRE A;  3BLX B;  1PS6 A;  4BNP A;  3TY4 A;  1OSJ A;  4YB4 A;  5DE1 A;  1IKA A;  2QFW A;  1XKD A;  4I3L A;  1IDD A;  1V94 A;  1XAD A;  4AOY A;  1IDC A;  2UXQ A;  6ICD A;  7ICD A;  5GRL A;  1V5B A;  3WZV A;  3WZY A;  2Y3Z A;  4WUO A;  4AOU A;  1AI2 A;  2D4V A;  1ZOR A;  1T0L A;  1DR8 A;  5ICD A;  3WZX A;  3ASJ A;  1GRP A;  1LWD A;  4IWH A;  1WPW A;  1G2U A;  4AJS A;  1V53 A;  5GRF B;  1PB1 A;  2QFX A;  4AJC A;  1XAB A;  1PTM A;  1DR0 A; 
#chains in the Genus database with same CATH homology
 9ICD A;  3R8W A;  1WAL A;  4UMX A;  2UXR A;  4P69 C;  5J32 A;  1X0L A;  1VLC A;  4Y1P A;  3VL2 A;  1IPD A;  3INM A;  3BLV A;  1GC8 A;  1CW4 A;  5GRI A;  3UF6 A;  3AH3 A;  4XRX A;  1XAC A;  4AJA A;  5GRH B;  3WZW A;  4L06 A;  2HI1 A;  3MAS B;  3VMJ A;  3VL4 A;  5GRE B;  3UDO A;  1IDM A;  1PB3 A;  3U9E A;  5K10 A;  8ICD A;  1GRO A;  3BLX A;  2IV0 A;  4XS3 A;  5HN3 A;  1OSI A;  1IDE A;  4JQP A;  3LCB C;  1A05 A;  1U7N A;  4I3K A;  5GRL B;  3U1H A;  3TSN A;  2E0C A;  1HQS A;  3VL6 A;  5K11 A;  1HJ6 A;  3FMX X;  3VL7 A;  3MAR A;  1CNZ A;  1T09 A;  5HN4 A;  1BL5 A;  5HN5 A;  2Y41 A;  3ICD A;  4F7I A;  5I95 A;  1VI1 A;  2D1C A;  1HEX A;  1YXO A;  5I96 A;  3TY3 A;  1ISO A;  1XGV A;  4HCX A;  4XXV A;  1IDF A;  3FLK A;  1P8F A;  4AOV A;  1GC9 A;  4AJB A;  1AI3 A;  3DMS A;  5J34 A;  5L58 A;  2Y42 A;  5J33 A;  5HN6 A;  3US8 A;  1DPZ A;  2QFY A;  1R8K A;  4JA8 A;  4L04 A;  3VL3 A;  4ATY A;  5GRF A;  3UDU A;  5L57 A;  5LGE A;  3VKZ A;  2E5M A;  1CW7 A;  2ZTW A;  3VML A;  1YCO A;  1PS7 A;  1CM7 A;  3VMK A;  4AJ3 A;  4ICD A;  3BLV B;  3LXY A;  2QFV A;  5GRI B;  3TNG A;  1SJS A;  1TYO A;  2G4O A;  4UMY A;  1CW1 A;  2Y40 A;  5GRH A;  1XAA A;  2DHT A;  3MAP A;  3MAS A;  2AYQ A;  1W0D A;  4KZO A;  4L03 A;  4AJR A;  5GRE A;  3BLX B;  1PS6 A;  4BNP A;  3TY4 A;  1OSJ A;  4YB4 A;  5DE1 A;  1IKA A;  2QFW A;  1XKD A;  4I3L A;  1IDD A;  1V94 A;  1XAD A;  4AOY A;  1IDC A;  2UXQ A;  6ICD A;  7ICD A;  5GRL A;  1V5B A;  3WZV A;  3WZY A;  2Y3Z A;  4WUO A;  4AOU A;  1AI2 A;  2D4V A;  1ZOR A;  1T0L A;  1DR8 A;  5ICD A;  3WZX A;  3ASJ A;  1GRP A;  1LWD A;  4IWH A;  1WPW A;  1G2U A;  4AJS A;  1V53 A;  5GRF B;  1PB1 A;  2QFX A;  4AJC A;  1XAB A;  1PTM A;  1DR0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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