3WVIA

Time-resolved crystal structure of hindiii with 40 sec soaking
Total Genus 113
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
113
sequence length
298
structure length
298
Chain Sequence
KSALEKLLSLIENLTNQEFKQATNSLISFIYKLNRNEVIELVRSIGILPEAIKPSSTQEKLFSKAGDIVLAKAFQLLNLNSKPLEQRGNAGDVIALSKEFNYGLVADAKSFRLSRTAKNQKDFKVKALSEWREDKDYAVLTAPFFQYPTTKSQIFKQSLDENVLLFSWEHLAILLQLDLEETNIFSFEQLWNFPKKQSKKTSVSDAENNFMRDFNKYFMDLFKIDKDTLNQLLQKEINFIEERSLIEKEYWKKQINIIKNFTREEAIEALLKDINMSSKIETIDSFIKGIKSNDRLYL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Analysis of the HindIII-catalyzed reaction by time-resolved crystallography
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Haemophilus influenzae
molecule keywords Type-2 restriction enzyme HindIII
total genus 113
structure length 298
sequence length 298
chains with identical sequence B, C, D
ec nomenclature ec 3.1.21.4: Type II site-specific deoxyribonuclease.
pdb deposition date 2014-05-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09518 RE_HindIII HindIII restriction endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.91.70 Alpha Beta 3-Layer(aba) Sandwich Restriction Endonuclease Restriction Endonuclease 3wviA01
3WVGA 3WVIA 3WVHA 2E52A 3WVPA 3WVKA 3A4KA
chains in the Genus database with same CATH superfamily
3HW5A 5DEBA 1D2IA 4AVGA 4F0PA 5I13A 5D2OA 1SDOA 4E5EA 4R28A 3HW6A 4AWFA 1ES8A 3WVHA 4E5FA 1M0DA 5D8UA 3HW3A 4ZQQA 3ODHA 4NFZA 3WVIA 4E5GA 3DW9A 3N7BA 3A4KA 3CAEA 3V20A 4AVQA 4AWMA 3WVGA 2P0JA 4CGSA 3BAMA 5FDGA 4CHCA 5EGAA 1ESGA 2FQZA 5CL0A 3N78A 3V1ZA 2BAMA 2E52A 2XI7A 3V21A 3DVOA 2EWFA 5DBSA 5D9JA 4CGXA 1KNVA 1DC1A 1M0IA 2FOKA 3MQYA 2P14A 4E5HA 3EBJA 1BHMA 4E5LA 3HW4A 5CZNA 4YYLA 1FOKA 3DPGA 1BAMA 2XI5A 5DESA 4F0QA 4E5JA 3WVPA 2GB7A 4E5IA 3BM3A 4OC8A 5FDDA 1FZRA 4ZHZA 4ZI0A 5CCYA 2PFJA 4AWHA 5D4GA 5JHVA 1CFRA 1VRRA 5JHTA 5CGVA 4AWGA 4AVLA 3MQ6A 1DFMA 5D42A 3WVKA 4AWKA
chains in the Genus database with same CATH topology
3HW5A 5DEBA 1D2IA 4AVGA 4F0PA 5I13A 5D2OA 1SDOA 4E5EA 4R28A 3HW6A 4AWFA 1ES8A 3WVHA 4E5FA 1M0DA 5D8UA 3HW3A 4ZQQA 3ODHA 4NFZA 3WVIA 4E5GA 3DW9A 3N7BA 3A4KA 3CAEA 3V20A 4AVQA 4AWMA 3WVGA 2P0JA 4CGSA 3BAMA 5FDGA 4CHCA 5EGAA 1ESGA 2FQZA 5CL0A 3N78A 3V1ZA 2BAMA 2E52A 2XI7A 3V21A 3DVOA 2EWFA 5DBSA 5D9JA 4CGXA 1KNVA 1DC1A 1M0IA 2FOKA 3MQYA 2P14A 4E5HA 3EBJA 1BHMA 4E5LA 3HW4A 5CZNA 4YYLA 1FOKA 3DPGA 1BAMA 2XI5A 5DESA 4F0QA 4E5JA 3WVPA 2GB7A 4E5IA 3BM3A 4OC8A 5FDDA 1FZRA 4ZHZA 4ZI0A 5CCYA 2PFJA 4AWHA 5D4GA 5JHVA 1CFRA 1VRRA 5JHTA 5CGVA 4AWGA 4AVLA 3MQ6A 1DFMA 5D42A 3WVKA 4AWKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3WVG A;  3WVI A;  3WVH A;  2E52 A;  3WVP A;  3WVK A;  3A4K A; 
#chains in the Genus database with same CATH topology
 3HW5 A;  5DEB A;  1D2I A;  4AVG A;  4F0P A;  5I13 A;  5D2O A;  1SDO A;  4E5E A;  4R28 A;  3HW6 A;  4AWF A;  1ES8 A;  3WVH A;  4E5F A;  1M0D A;  5D8U A;  3HW3 A;  4ZQQ A;  3ODH A;  4NFZ A;  3WVI A;  4E5G A;  3DW9 A;  3N7B A;  3A4K A;  3CAE A;  3V20 A;  4AVQ A;  4AWM A;  3WVG A;  2P0J A;  4CGS A;  3BAM A;  5FDG A;  4CHC A;  5EGA A;  1ESG A;  2FQZ A;  5CL0 A;  3N78 A;  3V1Z A;  2BAM A;  2E52 A;  2XI7 A;  3V21 A;  3DVO A;  2EWF A;  5DBS A;  5D9J A;  4CGX A;  1KNV A;  1DC1 A;  1M0I A;  2FOK A;  3MQY A;  2P14 A;  4E5H A;  3EBJ A;  1BHM A;  4E5L A;  3HW4 A;  5CZN A;  4YYL A;  1FOK A;  3DPG A;  1BAM A;  2XI5 A;  5DES A;  4F0Q A;  4E5J A;  3WVP A;  2GB7 A;  4E5I A;  3BM3 A;  4OC8 A;  5FDD A;  1FZR A;  4ZHZ A;  4ZI0 A;  5CCY A;  2PFJ A;  4AWH A;  5D4G A;  5JHV A;  1CFR A;  1VRR A;  5JHT A;  5CGV A;  4AWG A;  4AVL A;  3MQ6 A;  1DFM A;  5D42 A;  3WVK A;  4AWK A; 
#chains in the Genus database with same CATH homology
 3HW5 A;  5DEB A;  1D2I A;  4AVG A;  4F0P A;  5I13 A;  5D2O A;  1SDO A;  4E5E A;  4R28 A;  3HW6 A;  4AWF A;  1ES8 A;  3WVH A;  4E5F A;  1M0D A;  5D8U A;  3HW3 A;  4ZQQ A;  3ODH A;  4NFZ A;  3WVI A;  4E5G A;  3DW9 A;  3N7B A;  3A4K A;  3CAE A;  3V20 A;  4AVQ A;  4AWM A;  3WVG A;  2P0J A;  4CGS A;  3BAM A;  5FDG A;  4CHC A;  5EGA A;  1ESG A;  2FQZ A;  5CL0 A;  3N78 A;  3V1Z A;  2BAM A;  2E52 A;  2XI7 A;  3V21 A;  3DVO A;  2EWF A;  5DBS A;  5D9J A;  4CGX A;  1KNV A;  1DC1 A;  1M0I A;  2FOK A;  3MQY A;  2P14 A;  4E5H A;  3EBJ A;  1BHM A;  4E5L A;  3HW4 A;  5CZN A;  4YYL A;  1FOK A;  3DPG A;  1BAM A;  2XI5 A;  5DES A;  4F0Q A;  4E5J A;  3WVP A;  2GB7 A;  4E5I A;  3BM3 A;  4OC8 A;  5FDD A;  1FZR A;  4ZHZ A;  4ZI0 A;  5CCY A;  2PFJ A;  4AWH A;  5D4G A;  5JHV A;  1CFR A;  1VRR A;  5JHT A;  5CGV A;  4AWG A;  4AVL A;  3MQ6 A;  1DFM A;  5D42 A;  3WVK A;  4AWK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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