3WVPA

Time-resolved crystal structure of hindiii with 60sec soaking
Total Genus 111
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
111
sequence length
298
structure length
298
Chain Sequence
KSALEKLLSLIENLTNQEFKQATNSLISFIYKLNRNEVIELVRSIGILPEAIKPSSTQEKLFSKAGDIVLAKAFQLLNLNSKPLEQRGNAGDVIALSKEFNYGLVADAKSFRLSRTAKNQKDFKVKALSEWREDKDYAVLTAPFFQYPTTKSQIFKQSLDENVLLFSWEHLAILLQLDLEETNIFSFEQLWNFPKKQSKKTSVSDAENNFMRDFNKYFMDLFKIDKDTLNQLLQKEINFIEERSLIEKEYWKKQINIIKNFTREEAIEALLKDINMSSKIETIDSFIKGIKSNDRLYL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Analysis of the HindIII-catalyzed reaction by time-resolved crystallography
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Haemophilus influenzae
molecule keywords Type-2 restriction enzyme HindIII
total genus 111
structure length 298
sequence length 298
chains with identical sequence B, C, D
ec nomenclature ec 3.1.21.4: Type II site-specific deoxyribonuclease.
pdb deposition date 2014-06-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09518 RE_HindIII HindIII restriction endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.91.70 Alpha Beta 3-Layer(aba) Sandwich Restriction Endonuclease Restriction Endonuclease 3wvpA01
2E52A 3WVHA 3WVKA 3A4KA 3WVPA 3WVIA 3WVGA
chains in the Genus database with same CATH superfamily
3MQ6A 3V21A 4F0PA 3DVOA 5D4GA 1VRRA 4E5FA 1SDOA 1BAMA 3HW5A 3CAEA 4AWKA 3V20A 3HW6A 5CGVA 1M0DA 5D9JA 4E5GA 1D2IA 2GB7A 5CZNA 3WVPA 2E52A 3WVHA 5EGAA 3EBJA 4YYLA 3BAMA 1BHMA 2EWFA 4CGXA 3MQYA 3ODHA 4AWFA 5CL0A 5I13A 4E5JA 4E5IA 4AVGA 2FQZA 4NFZA 4ZI0A 4OC8A 4AVLA 4AVQA 4AWHA 2FOKA 4F0QA 5FDDA 1DFMA 3N78A 4E5EA 5D8UA 3DPGA 4R28A 3DW9A 2XI7A 4AWMA 5DBSA 4CHCA 2XI5A 4E5HA 4AWGA 1ES8A 2P0JA 3WVGA 1DC1A 3A4KA 4CGSA 4E5LA 4ZHZA 3HW4A 1M0IA 5D2OA 5DEBA 2PFJA 3V1ZA 1ESGA 4ZQQA 1CFRA 3N7BA 3WVKA 1FZRA 5CCYA 3BM3A 5JHVA 5JHTA 2P14A 5DESA 1FOKA 3WVIA 2BAMA 5FDGA 1KNVA 5D42A 3HW3A
chains in the Genus database with same CATH topology
3MQ6A 3V21A 4F0PA 3DVOA 5D4GA 1VRRA 4E5FA 1SDOA 1BAMA 3HW5A 3CAEA 4AWKA 3V20A 3HW6A 5CGVA 1M0DA 5D9JA 4E5GA 1D2IA 2GB7A 5CZNA 3WVPA 2E52A 3WVHA 5EGAA 3EBJA 4YYLA 3BAMA 1BHMA 2EWFA 4CGXA 3MQYA 3ODHA 4AWFA 5CL0A 5I13A 4E5JA 4E5IA 4AVGA 2FQZA 4NFZA 4ZI0A 4OC8A 4AVLA 4AVQA 4AWHA 2FOKA 4F0QA 5FDDA 1DFMA 3N78A 4E5EA 5D8UA 3DPGA 4R28A 3DW9A 2XI7A 4AWMA 5DBSA 4CHCA 2XI5A 4E5HA 4AWGA 1ES8A 2P0JA 3WVGA 1DC1A 3A4KA 4CGSA 4E5LA 4ZHZA 3HW4A 1M0IA 5D2OA 5DEBA 2PFJA 3V1ZA 1ESGA 4ZQQA 1CFRA 3N7BA 3WVKA 1FZRA 5CCYA 3BM3A 5JHVA 5JHTA 2P14A 5DESA 1FOKA 3WVIA 2BAMA 5FDGA 1KNVA 5D42A 3HW3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2E52 A;  3WVH A;  3WVK A;  3A4K A;  3WVP A;  3WVI A;  3WVG A; 
#chains in the Genus database with same CATH topology
 3MQ6 A;  3V21 A;  4F0P A;  3DVO A;  5D4G A;  1VRR A;  4E5F A;  1SDO A;  1BAM A;  3HW5 A;  3CAE A;  4AWK A;  3V20 A;  3HW6 A;  5CGV A;  1M0D A;  5D9J A;  4E5G A;  1D2I A;  2GB7 A;  5CZN A;  3WVP A;  2E52 A;  3WVH A;  5EGA A;  3EBJ A;  4YYL A;  3BAM A;  1BHM A;  2EWF A;  4CGX A;  3MQY A;  3ODH A;  4AWF A;  5CL0 A;  5I13 A;  4E5J A;  4E5I A;  4AVG A;  2FQZ A;  4NFZ A;  4ZI0 A;  4OC8 A;  4AVL A;  4AVQ A;  4AWH A;  2FOK A;  4F0Q A;  5FDD A;  1DFM A;  3N78 A;  4E5E A;  5D8U A;  3DPG A;  4R28 A;  3DW9 A;  2XI7 A;  4AWM A;  5DBS A;  4CHC A;  2XI5 A;  4E5H A;  4AWG A;  1ES8 A;  2P0J A;  3WVG A;  1DC1 A;  3A4K A;  4CGS A;  4E5L A;  4ZHZ A;  3HW4 A;  1M0I A;  5D2O A;  5DEB A;  2PFJ A;  3V1Z A;  1ESG A;  4ZQQ A;  1CFR A;  3N7B A;  3WVK A;  1FZR A;  5CCY A;  3BM3 A;  5JHV A;  5JHT A;  2P14 A;  5DES A;  1FOK A;  3WVI A;  2BAM A;  5FDG A;  1KNV A;  5D42 A;  3HW3 A; 
#chains in the Genus database with same CATH homology
 3MQ6 A;  3V21 A;  4F0P A;  3DVO A;  5D4G A;  1VRR A;  4E5F A;  1SDO A;  1BAM A;  3HW5 A;  3CAE A;  4AWK A;  3V20 A;  3HW6 A;  5CGV A;  1M0D A;  5D9J A;  4E5G A;  1D2I A;  2GB7 A;  5CZN A;  3WVP A;  2E52 A;  3WVH A;  5EGA A;  3EBJ A;  4YYL A;  3BAM A;  1BHM A;  2EWF A;  4CGX A;  3MQY A;  3ODH A;  4AWF A;  5CL0 A;  5I13 A;  4E5J A;  4E5I A;  4AVG A;  2FQZ A;  4NFZ A;  4ZI0 A;  4OC8 A;  4AVL A;  4AVQ A;  4AWH A;  2FOK A;  4F0Q A;  5FDD A;  1DFM A;  3N78 A;  4E5E A;  5D8U A;  3DPG A;  4R28 A;  3DW9 A;  2XI7 A;  4AWM A;  5DBS A;  4CHC A;  2XI5 A;  4E5H A;  4AWG A;  1ES8 A;  2P0J A;  3WVG A;  1DC1 A;  3A4K A;  4CGS A;  4E5L A;  4ZHZ A;  3HW4 A;  1M0I A;  5D2O A;  5DEB A;  2PFJ A;  3V1Z A;  1ESG A;  4ZQQ A;  1CFR A;  3N7B A;  3WVK A;  1FZR A;  5CCY A;  3BM3 A;  5JHV A;  5JHT A;  2P14 A;  5DES A;  1FOK A;  3WVI A;  2BAM A;  5FDG A;  1KNV A;  5D42 A;  3HW3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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