3WZVA

3-isopropylmalate dehydrogenase from shewanella oneidensis mr-1 at 0.1mpa - complex with ipm and mg
Total Genus 128
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
128
sequence length
364
structure length
364
Chain Sequence
SSYQIAVLAGDGIGPEVMAEARKVLKAVEARFGLNIEYTEYDVGGIAIDNHGCPLPEATLKGCEAADAILFGSVGGPKWEKLPPNEQPERGALLPLRGHFELFCNLRPAKLHDGLEHMSPLRSDISARGFDVLCVRELTGGIYFGKPKGRQGEGESEEAFDTMRYSRREISRIARIAFEAARGRRKKVTSVDKANVLACSVLWRQVVEEVAVDFPDVELEHIYIDNATMQLLRRPDEFDVMLCSNLFGDILSDEIAMLTGSMGLLSSASMNSTGFGLFEPAGGSAPDIAGKGIANPIAQILSAALMLRHSLKQEEAASAIERAVTKALNSGYLTGELLSSDQRHKAKTTVQMGDFIADAVKAGV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Pressure Adaptation of 3-Isopropylmalate Dehydrogenase from the Extremely Piezophilic Bacterium Shewanella benthica is Attributed to just One Amino Acid Substitution
rcsb
molecule tags Oxidoreductase
source organism Shewanella oneidensis mr-1
molecule keywords 3-isopropylmalate dehydrogenase
total genus 128
structure length 364
sequence length 364
ec nomenclature ec 1.1.1.85: 3-isopropylmalate dehydrogenase.
pdb deposition date 2014-10-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00180 Iso_dh Isocitrate/isopropylmalate dehydrogenase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.718.10 Alpha Beta 3-Layer(aba) Sandwich Isopropylmalate Dehydrogenase Isopropylmalate Dehydrogenase 3wzvA00
2D4VA 3VL4A 4BNPA 1G2UA 4ICDA 1BL5A 3MARA 1IPDA 3UDUA 3FLKA 2QFVA 3MASA 1V5BA 5GRIA 1CNZA 3VL3A 4Y1PA 2E0CA 1HEXA 1V53A 2Y40A 5GRLA 1XACA 4AJ3A 4L06A 1AI2A 4AJBA 4AOVA 1XADA 4F7IA 1OSIA 4XRXA 3VMJA 4I3LA 1CW1A 4UMXA 7ICDA 5GRHB 4IWHA 3AH3A 9ICDA 2HI1A 4JA8A 5HN4A 4HCXA 5HN3A 1IDEA 1WALA 1LWDA 5K10A 2D1CA 1CW7A 4L04A 3U9EA 3WZWA 3VL6A 1T09A 1PTMA 2Y41A 4WUOA 1XABA 3VMLA 3WZXA 1T0LA 5I96A 2ZTWA 4AJCA 3TSNA 1GROA 1IKAA 1PS6A 4ATYA 2E5MA 3TNGA 3VL2A 1A05A 5GRFA 5GREA 1VLCA 1ISOA 4I3KA 1PS7A 4JQPA 6ICDA 5I95A 5ICDA 3US8A 1OSJA 5GRHA 3MAPA 3DMSA 3U1HA 8ICDA 5HN6A 1TYOA 1WPWA 4XS3A 4AOUA 3MASB 2UXQA 5GRIB 4XXVA 1CM7A 3BLXB 1YCOA 1HQSA 2Y42A 3VMKA 5J33A 4L03A 5GRLB 5L57A 1V94A 5DE1A 1ZORA 1IDDA 4KZOA 5J34A 1XAAA 3ASJA 3VKZA 3WZVA 2G4OA 3INMA 1YXOA 1DPZA 1CW4A 1W0DA 1X0LA 3VL7A 4AJRA 2QFXA 3UDOA 3BLVB 3LCBC 1HJ6A 1PB1A 3UF6A 1R8KA 2IV0A 3FMXX 2QFWA 1GC8A 1IDFA 1XGVA 4YB4A 5L58A 1SJSA 1VI1A 4P69C 3BLXA 4UMYA 1XKDA 2AYQA 1GC9A 1IDCA 2QFYA 2UXRA 3R8WA 2Y3ZA 1AI3A 3ICDA 5HN5A 4AJAA 4AJSA 5J32A 3WZYA 1U7NA 1DR8A 5GRFB 3TY3A 5GREB 2DHTA 1GRPA 3LXYA 1DR0A 1IDMA 1P8FA 3TY4A 5LGEA 4AOYA 3BLVA 5K11A 1PB3A
chains in the Genus database with same CATH superfamily
2D4VA 3VL4A 4BNPA 1G2UA 4ICDA 1BL5A 3MARA 1IPDA 3UDUA 3FLKA 2QFVA 3MASA 1V5BA 5GRIA 1CNZA 3VL3A 4Y1PA 2E0CA 1HEXA 1V53A 2Y40A 5GRLA 1XACA 4AJ3A 4L06A 1AI2A 4AJBA 4AOVA 1XADA 4F7IA 1OSIA 4XRXA 3VMJA 4I3LA 1CW1A 4UMXA 7ICDA 5GRHB 4IWHA 3AH3A 9ICDA 2HI1A 4JA8A 5HN4A 4HCXA 5HN3A 1IDEA 1WALA 1LWDA 5K10A 2D1CA 1CW7A 4L04A 3U9EA 3WZWA 3VL6A 1T09A 1PTMA 2Y41A 4WUOA 1XABA 3VMLA 3WZXA 1T0LA 5I96A 2ZTWA 4AJCA 3TSNA 1GROA 1IKAA 1PS6A 4ATYA 2E5MA 3TNGA 3VL2A 1A05A 5GRFA 5GREA 1VLCA 1ISOA 4I3KA 1PS7A 4JQPA 6ICDA 5I95A 5ICDA 3US8A 1OSJA 5GRHA 3MAPA 3DMSA 3U1HA 8ICDA 5HN6A 1TYOA 1WPWA 4XS3A 4AOUA 3MASB 2UXQA 5GRIB 4XXVA 1CM7A 3BLXB 1YCOA 1HQSA 2Y42A 3VMKA 5J33A 4L03A 5GRLB 5L57A 1V94A 5DE1A 1ZORA 1IDDA 4KZOA 5J34A 1XAAA 3ASJA 3VKZA 3WZVA 2G4OA 3INMA 1YXOA 1DPZA 1CW4A 1W0DA 1X0LA 3VL7A 4AJRA 2QFXA 3UDOA 3BLVB 3LCBC 1HJ6A 1PB1A 3UF6A 1R8KA 2IV0A 3FMXX 2QFWA 1GC8A 1IDFA 1XGVA 4YB4A 5L58A 1SJSA 1VI1A 4P69C 3BLXA 4UMYA 1XKDA 2AYQA 1GC9A 1IDCA 2QFYA 2UXRA 3R8WA 2Y3ZA 1AI3A 3ICDA 5HN5A 4AJAA 4AJSA 5J32A 3WZYA 1U7NA 1DR8A 5GRFB 3TY3A 5GREB 2DHTA 1GRPA 3LXYA 1DR0A 1IDMA 1P8FA 3TY4A 5LGEA 4AOYA 3BLVA 5K11A 1PB3A
chains in the Genus database with same CATH topology
2D4VA 3VL4A 4BNPA 1G2UA 4ICDA 1BL5A 3MARA 1IPDA 3UDUA 3FLKA 2QFVA 3MASA 1V5BA 5GRIA 1CNZA 3VL3A 4Y1PA 2E0CA 1HEXA 1V53A 2Y40A 5GRLA 1XACA 4AJ3A 4L06A 1AI2A 4AJBA 4AOVA 1XADA 4F7IA 1OSIA 4XRXA 3VMJA 4I3LA 1CW1A 4UMXA 7ICDA 5GRHB 4IWHA 3AH3A 9ICDA 2HI1A 4JA8A 5HN4A 4HCXA 5HN3A 1IDEA 1WALA 1LWDA 5K10A 2D1CA 1CW7A 4L04A 3U9EA 3WZWA 3VL6A 1T09A 1PTMA 2Y41A 4WUOA 1XABA 3VMLA 3WZXA 1T0LA 5I96A 2ZTWA 4AJCA 3TSNA 1GROA 1IKAA 1PS6A 4ATYA 2E5MA 3TNGA 3VL2A 1A05A 5GRFA 5GREA 1VLCA 1ISOA 4I3KA 1PS7A 4JQPA 6ICDA 5I95A 5ICDA 3US8A 1OSJA 5GRHA 3MAPA 3DMSA 3U1HA 8ICDA 5HN6A 1TYOA 1WPWA 4XS3A 4AOUA 3MASB 2UXQA 5GRIB 4XXVA 1CM7A 3BLXB 1YCOA 1HQSA 2Y42A 3VMKA 5J33A 4L03A 5GRLB 5L57A 1V94A 5DE1A 1ZORA 1IDDA 4KZOA 5J34A 1XAAA 3ASJA 3VKZA 3WZVA 2G4OA 3INMA 1YXOA 1DPZA 1CW4A 1W0DA 1X0LA 3VL7A 4AJRA 2QFXA 3UDOA 3BLVB 3LCBC 1HJ6A 1PB1A 3UF6A 1R8KA 2IV0A 3FMXX 2QFWA 1GC8A 1IDFA 1XGVA 4YB4A 5L58A 1SJSA 1VI1A 4P69C 3BLXA 4UMYA 1XKDA 2AYQA 1GC9A 1IDCA 2QFYA 2UXRA 3R8WA 2Y3ZA 1AI3A 3ICDA 5HN5A 4AJAA 4AJSA 5J32A 3WZYA 1U7NA 1DR8A 5GRFB 3TY3A 5GREB 2DHTA 1GRPA 3LXYA 1DR0A 1IDMA 1P8FA 3TY4A 5LGEA 4AOYA 3BLVA 5K11A 1PB3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2D4V A;  3VL4 A;  4BNP A;  1G2U A;  4ICD A;  1BL5 A;  3MAR A;  1IPD A;  3UDU A;  3FLK A;  2QFV A;  3MAS A;  1V5B A;  5GRI A;  1CNZ A;  3VL3 A;  4Y1P A;  2E0C A;  1HEX A;  1V53 A;  2Y40 A;  5GRL A;  1XAC A;  4AJ3 A;  4L06 A;  1AI2 A;  4AJB A;  4AOV A;  1XAD A;  4F7I A;  1OSI A;  4XRX A;  3VMJ A;  4I3L A;  1CW1 A;  4UMX A;  7ICD A;  5GRH B;  4IWH A;  3AH3 A;  9ICD A;  2HI1 A;  4JA8 A;  5HN4 A;  4HCX A;  5HN3 A;  1IDE A;  1WAL A;  1LWD A;  5K10 A;  2D1C A;  1CW7 A;  4L04 A;  3U9E A;  3WZW A;  3VL6 A;  1T09 A;  1PTM A;  2Y41 A;  4WUO A;  1XAB A;  3VML A;  3WZX A;  1T0L A;  5I96 A;  2ZTW A;  4AJC A;  3TSN A;  1GRO A;  1IKA A;  1PS6 A;  4ATY A;  2E5M A;  3TNG A;  3VL2 A;  1A05 A;  5GRF A;  5GRE A;  1VLC A;  1ISO A;  4I3K A;  1PS7 A;  4JQP A;  6ICD A;  5I95 A;  5ICD A;  3US8 A;  1OSJ A;  5GRH A;  3MAP A;  3DMS A;  3U1H A;  8ICD A;  5HN6 A;  1TYO A;  1WPW A;  4XS3 A;  4AOU A;  3MAS B;  2UXQ A;  5GRI B;  4XXV A;  1CM7 A;  3BLX B;  1YCO A;  1HQS A;  2Y42 A;  3VMK A;  5J33 A;  4L03 A;  5GRL B;  5L57 A;  1V94 A;  5DE1 A;  1ZOR A;  1IDD A;  4KZO A;  5J34 A;  1XAA A;  3ASJ A;  3VKZ A;  3WZV A;  2G4O A;  3INM A;  1YXO A;  1DPZ A;  1CW4 A;  1W0D A;  1X0L A;  3VL7 A;  4AJR A;  2QFX A;  3UDO A;  3BLV B;  3LCB C;  1HJ6 A;  1PB1 A;  3UF6 A;  1R8K A;  2IV0 A;  3FMX X;  2QFW A;  1GC8 A;  1IDF A;  1XGV A;  4YB4 A;  5L58 A;  1SJS A;  1VI1 A;  4P69 C;  3BLX A;  4UMY A;  1XKD A;  2AYQ A;  1GC9 A;  1IDC A;  2QFY A;  2UXR A;  3R8W A;  2Y3Z A;  1AI3 A;  3ICD A;  5HN5 A;  4AJA A;  4AJS A;  5J32 A;  3WZY A;  1U7N A;  1DR8 A;  5GRF B;  3TY3 A;  5GRE B;  2DHT A;  1GRP A;  3LXY A;  1DR0 A;  1IDM A;  1P8F A;  3TY4 A;  5LGE A;  4AOY A;  3BLV A;  5K11 A;  1PB3 A; 
#chains in the Genus database with same CATH topology
 2D4V A;  3VL4 A;  4BNP A;  1G2U A;  4ICD A;  1BL5 A;  3MAR A;  1IPD A;  3UDU A;  3FLK A;  2QFV A;  3MAS A;  1V5B A;  5GRI A;  1CNZ A;  3VL3 A;  4Y1P A;  2E0C A;  1HEX A;  1V53 A;  2Y40 A;  5GRL A;  1XAC A;  4AJ3 A;  4L06 A;  1AI2 A;  4AJB A;  4AOV A;  1XAD A;  4F7I A;  1OSI A;  4XRX A;  3VMJ A;  4I3L A;  1CW1 A;  4UMX A;  7ICD A;  5GRH B;  4IWH A;  3AH3 A;  9ICD A;  2HI1 A;  4JA8 A;  5HN4 A;  4HCX A;  5HN3 A;  1IDE A;  1WAL A;  1LWD A;  5K10 A;  2D1C A;  1CW7 A;  4L04 A;  3U9E A;  3WZW A;  3VL6 A;  1T09 A;  1PTM A;  2Y41 A;  4WUO A;  1XAB A;  3VML A;  3WZX A;  1T0L A;  5I96 A;  2ZTW A;  4AJC A;  3TSN A;  1GRO A;  1IKA A;  1PS6 A;  4ATY A;  2E5M A;  3TNG A;  3VL2 A;  1A05 A;  5GRF A;  5GRE A;  1VLC A;  1ISO A;  4I3K A;  1PS7 A;  4JQP A;  6ICD A;  5I95 A;  5ICD A;  3US8 A;  1OSJ A;  5GRH A;  3MAP A;  3DMS A;  3U1H A;  8ICD A;  5HN6 A;  1TYO A;  1WPW A;  4XS3 A;  4AOU A;  3MAS B;  2UXQ A;  5GRI B;  4XXV A;  1CM7 A;  3BLX B;  1YCO A;  1HQS A;  2Y42 A;  3VMK A;  5J33 A;  4L03 A;  5GRL B;  5L57 A;  1V94 A;  5DE1 A;  1ZOR A;  1IDD A;  4KZO A;  5J34 A;  1XAA A;  3ASJ A;  3VKZ A;  3WZV A;  2G4O A;  3INM A;  1YXO A;  1DPZ A;  1CW4 A;  1W0D A;  1X0L A;  3VL7 A;  4AJR A;  2QFX A;  3UDO A;  3BLV B;  3LCB C;  1HJ6 A;  1PB1 A;  3UF6 A;  1R8K A;  2IV0 A;  3FMX X;  2QFW A;  1GC8 A;  1IDF A;  1XGV A;  4YB4 A;  5L58 A;  1SJS A;  1VI1 A;  4P69 C;  3BLX A;  4UMY A;  1XKD A;  2AYQ A;  1GC9 A;  1IDC A;  2QFY A;  2UXR A;  3R8W A;  2Y3Z A;  1AI3 A;  3ICD A;  5HN5 A;  4AJA A;  4AJS A;  5J32 A;  3WZY A;  1U7N A;  1DR8 A;  5GRF B;  3TY3 A;  5GRE B;  2DHT A;  1GRP A;  3LXY A;  1DR0 A;  1IDM A;  1P8F A;  3TY4 A;  5LGE A;  4AOY A;  3BLV A;  5K11 A;  1PB3 A; 
#chains in the Genus database with same CATH homology
 2D4V A;  3VL4 A;  4BNP A;  1G2U A;  4ICD A;  1BL5 A;  3MAR A;  1IPD A;  3UDU A;  3FLK A;  2QFV A;  3MAS A;  1V5B A;  5GRI A;  1CNZ A;  3VL3 A;  4Y1P A;  2E0C A;  1HEX A;  1V53 A;  2Y40 A;  5GRL A;  1XAC A;  4AJ3 A;  4L06 A;  1AI2 A;  4AJB A;  4AOV A;  1XAD A;  4F7I A;  1OSI A;  4XRX A;  3VMJ A;  4I3L A;  1CW1 A;  4UMX A;  7ICD A;  5GRH B;  4IWH A;  3AH3 A;  9ICD A;  2HI1 A;  4JA8 A;  5HN4 A;  4HCX A;  5HN3 A;  1IDE A;  1WAL A;  1LWD A;  5K10 A;  2D1C A;  1CW7 A;  4L04 A;  3U9E A;  3WZW A;  3VL6 A;  1T09 A;  1PTM A;  2Y41 A;  4WUO A;  1XAB A;  3VML A;  3WZX A;  1T0L A;  5I96 A;  2ZTW A;  4AJC A;  3TSN A;  1GRO A;  1IKA A;  1PS6 A;  4ATY A;  2E5M A;  3TNG A;  3VL2 A;  1A05 A;  5GRF A;  5GRE A;  1VLC A;  1ISO A;  4I3K A;  1PS7 A;  4JQP A;  6ICD A;  5I95 A;  5ICD A;  3US8 A;  1OSJ A;  5GRH A;  3MAP A;  3DMS A;  3U1H A;  8ICD A;  5HN6 A;  1TYO A;  1WPW A;  4XS3 A;  4AOU A;  3MAS B;  2UXQ A;  5GRI B;  4XXV A;  1CM7 A;  3BLX B;  1YCO A;  1HQS A;  2Y42 A;  3VMK A;  5J33 A;  4L03 A;  5GRL B;  5L57 A;  1V94 A;  5DE1 A;  1ZOR A;  1IDD A;  4KZO A;  5J34 A;  1XAA A;  3ASJ A;  3VKZ A;  3WZV A;  2G4O A;  3INM A;  1YXO A;  1DPZ A;  1CW4 A;  1W0D A;  1X0L A;  3VL7 A;  4AJR A;  2QFX A;  3UDO A;  3BLV B;  3LCB C;  1HJ6 A;  1PB1 A;  3UF6 A;  1R8K A;  2IV0 A;  3FMX X;  2QFW A;  1GC8 A;  1IDF A;  1XGV A;  4YB4 A;  5L58 A;  1SJS A;  1VI1 A;  4P69 C;  3BLX A;  4UMY A;  1XKD A;  2AYQ A;  1GC9 A;  1IDC A;  2QFY A;  2UXR A;  3R8W A;  2Y3Z A;  1AI3 A;  3ICD A;  5HN5 A;  4AJA A;  4AJS A;  5J32 A;  3WZY A;  1U7N A;  1DR8 A;  5GRF B;  3TY3 A;  5GRE B;  2DHT A;  1GRP A;  3LXY A;  1DR0 A;  1IDM A;  1P8F A;  3TY4 A;  5LGE A;  4AOY A;  3BLV A;  5K11 A;  1PB3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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